Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,048 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07664709Recruiting
Eye problems in granulomatosis with polyangiitis study
This study looks at eye problems in people who have a disease called granulomatosis with polyangiitis (GPA), which is a type of blood vessel inflammation that can also affect the eyes. They want to understand what eye issues happen in this disease.
WarsawAges 18 years+ - NCT03314974RecruitingPhase 2
Stem cell transplant study for blood cancers
This Phase 2 study tests a strong (myeloablative) stem cell transplant using donor stem cells (allogeneic transplant) for certain blood and bone marrow cancers. The goal is to see how well this approach works and whether it can improve outcomes for people who need transplant-level treatment.
Minneapolis, MinnesotaAges Up to 60 years - NCT06269965Recruiting
Collagen membrane for rotator cuff repair
This trial tests whether using a special collagen membrane helps improve healing when repairing a torn rotator cuff tendon. It is for people who have a tear in the upper part of the rotator cuff and are having surgery to fix it.
LyonAges 18 years+ - NCT06265519Recruiting
Urine markers for enlarged prostate check
This study looks at two natural substances in urine (BDNF and NGF) to see if they can help doctors understand how the lower urinary tract is working in men with an enlarged prostate. It is a simple, non-invasive test that may lead to better ways to diagnose and treat bladder problems.
IstanbulAges 50–80 - NCT06265584RecruitingPhase 2
Using ATG to prevent graft-versus-host disease after stem cell transplant
This trial tests if a two-step course of a drug called ATG (anti-thymocyte globulin) can help prevent a serious side effect called graft-versus-host disease (GVHD) after a donor stem cell transplant. It is for people with certain blood cancers who are receiving a reduced-intensity transplant.
Birmingham, AlabamaAges 18–75 - NCT06252948Recruiting
Gut bacteria study for POEMS and related plasma cell disorders
This study looks at the gut microbiome (the bacteria living in your digestive system) in people with POEMS syndrome, multiple myeloma, MGUS, amyloidosis, and healthy household members. It may help researchers understand how gut health relates to these conditions.
Rochester, MinnesotaAges 18 years+ - NCT06254313Recruiting
Studying neutrophils in flu-related lung injury
This trial looks at how a type of white blood cell affects lung inflammation in people with severe influenza. It may help researchers find better treatments for respiratory failure caused by the flu or other infections.
BordeauxAges 18 years+ - NCT06270771Recruiting
Using a wearable ring to monitor MDS patients at home
This study tests if people with MDS can comfortably wear the OURA ring (a smart ring) at home to track their health. The goal is to see if this is a useful way to monitor symptoms and well-being between doctor visits.
Toronto, OntarioAges 18 years+ - NCT06265038Recruiting
Study of a new implant for lower back fusion surgery
This study tests a new implant called ReSpace TiCell Cage for TLIF surgery, which is a procedure to stabilize the lower back by fusing two vertebrae. It may be a good option if you have a degenerative spine condition causing pain or instability and are a candidate for this type of surgery.
Budapest, Pest CountyAges 18–80 - NCT07552038Recruiting
Dental Care Management for People Living With HIV
This study looks at how dentists can best care for people with HIV. Researchers will review dental and health records at hospitals in the Pays de la Loire region to understand what works best for keeping teeth and gums healthy when you have HIV.
Nantes, NantesAges 18 years+ - NCT06246357RecruitingPhase 2
Testing adrenal gland function with a special scan
This trial uses a special PET scan (68Ga-PentixaFor) to check how well your adrenal glands are working if you have high aldosterone or cortisol levels. It helps doctors see if the glands are making too much hormone, which may guide treatment.
Bethesda, MarylandAges 18–120 - NCT06250699Recruiting
Rapid recovery after urologic surgery
This trial tests a program to help patients recover faster after urologic surgery. It focuses on making sure you heal well and get back to your normal life quickly.
Wuhan, HubeiAges 18–70 - NCT06247046RecruitingPhase 3
Probiotic powder for IBS-D (SK08) trial
This study tests a new probiotic powder (SK08) to see if it reduces belly pain and diarrhea in people with IBS-D (irritable bowel syndrome with diarrhea). It lasts several months and involves taking the study powder twice a day.
Wuxi, JiangsuAges 18–70 - NCT06230861Recruiting
Quercetin supplement for heart and metabolic health
This study tests whether taking a supplement called quercetin (a natural plant compound) improves heart and metabolic health markers in healthy adults. You'd take the supplement for a period of time, and researchers will measure things like blood sugar and cholesterol.
Preston, LancashireAges 18–65 - NCT06248957Recruiting
Immune system study for people with hard-to-treat immune diseases
This study aims to understand the immune system in people who have immune problems or whose immune-related diseases are not helped by standard treatments. It may lead to better ways to diagnose and treat these conditions.
StockholmAges Any age - NCT05537298Recruiting
Help for muscle recovery after serious ICU illness
This trial looks at how to improve muscle strength and function after a stay in the ICU for sepsis or acute respiratory failure. If you recover from the illness but your muscles become weak, this study may test an approach to help rebuild strength faster.
Birmingham, AlabamaAges 18 years+ - NCT06209346Recruiting
Remote physical therapy for chronic pelvic pain from endometriosis
This trial tests if a physical therapy program done at home through video calls can help reduce chronic pelvic pain in people with endometriosis. If you have ongoing pelvic pain and have already had medical or surgical treatment, this study may offer a new way to manage your pain.
Alcalà de Henares, MadridAges 18–55 - NCT06222866Recruiting
Blood thinner and inflammation monitoring after heart procedures
This study looks at how well blood thinners (anticoagulants) and inflammation markers work in people having heart or blood vessel procedures. It aims to better monitor these treatments to improve patient safety.
Innsbruck, TyrolAges 18 years+ - NCT06215222Recruiting
Studying gut bacteria in IBS and digestive issues
This study uses a tiny capsule to collect samples from your small intestine to learn about gut bacteria in people with IBS or other functional gut disorders. It could help researchers understand what causes digestive symptoms.
Redwood City, CaliforniaAges 18–70 - NCT06212492Recruiting
Muscle relaxants and stomach positioning for ARDS
This trial tests whether combining two treatments—medications that relax muscles (neuromuscular blocking agents) and lying on your stomach (prone positioning)—can reduce lung damage in people with severe ARDS on a breathing machine.
MarseilleAges 18 years+ - NCT06216821Recruiting
Personalized guide for timing blood-thinner reduction after a heart attack
This study tests whether a personalized score (OPT-CAD) can help decide the best time to stop or reduce blood-thinning medication in people who have had a heart attack and a stent placed. It aims to balance preventing future heart issues while lowering the risk of bleeding.
Shenyang, LiaoningAges 18–80 - NCT06207591Recruiting
Brain implant study for locked-in communication
This study tests a new brain implant (CortiCom) that may help people who are locked-in or nearly locked-in communicate again. It involves surgery to place the device in the brain and requires a caregiver and commitment to follow-up visits.
UtrechtAges 18–70 - NCT06211868Recruiting
Early heart disease risk study for adults 40-70
This study looks at whether changing your immune system, fats, and metabolism can lower your risk of early heart disease. It is for people with an intermediate to high risk score but who have not yet had a heart attack or stroke.
SingaporeAges 40–70 - NCT06208709Recruiting
Carpal tunnel treatment for right hand without surgery
This study tests a new way to treat carpal tunnel syndrome in the right hand without surgery. It may help people with mild to moderate symptoms who have not had recent injections or other treatments.
Tucson, ArizonaAges 18 years+
Hear when a new Down Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,048 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.