Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,173 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06366269Recruiting
Acupuncture first for bladder pain syndrome
This trial tests whether acupuncture can help relieve pain and pressure from bladder pain syndrome (also called interstitial cystitis). Researchers want to see if using acupuncture early can improve symptoms better than usual care.
Cleveland, OhioAges 18–89 - NCT06366230RecruitingPhase 1/Phase 2
Adding urea to final dialysis fluid
This trial tests adding urea to the final dialysis fluid for people with very high urea levels. It aims to make dialysis safer and more effective for those who need it urgently.
San Francisco, CaliforniaAges 18 years+ - NCT06369753Recruiting
Study on visible belly swelling after meals
This study looks at people whose belly visibly swells after eating. The goal is to understand this condition and track symptoms over time.
Los Angeles, CaliforniaAges 18–80 - NCT06371300Recruiting
Red vs Blue Light for Dry Eye With Mites
This study tests whether a special light (photobiomodulation) using red or blue light can help people with dry eye that is caused by both blocked oil glands and tiny eyelash mites. You'd receive 3 treatments, and we'd check how your eyes feel for a month after.
AucklandAges 18 years+ - NCT06371937Recruiting
Heart and blood vessel disease biobank study
This study creates a collection of skin cells (turned into stem cells in a lab) from people with various heart and blood vessel conditions. It aims to find new ways to understand and treat these diseases.
London, OntarioAges 18–80 - NCT06377059Recruiting
Early detection of complications during immunotherapy
This trial uses special equipment to watch for early side effects in people getting CAR T-cell therapy or bispecific antibodies for blood cancers, like lymphoma. It aims to catch problems early so they can be treated faster.
Copenhagen OAges 18 years+ - NCT06377254Recruiting
How activity or inactivity changes your body
This study looks at how changing your physical activity level (either becoming more or less active) affects your whole body over 6 months. It is for people aged 50–65 who are overweight and either quite sedentary or fairly active, and who are willing to change their routine.
Nottingham, NottsAges 50–65 - NCT06377878Recruiting
The Preeclampsia Registry
This study is building a registry of people who have had preeclampsia or related high blood pressure disorders during pregnancy, as well as their family members and healthy volunteers. The goal is to collect information that can help researchers better understand these conditions and improve care.
Melbourne, FloridaAges 13 years+ - NCT06378437RecruitingPhase 1
GLB-001 for blood cancers that have returned or not responded
This trial is testing a new drug called GLB-001 for people with certain blood cancers or bone marrow disorders that have not gotten better with standard treatments. The goal is to see if the drug is safe and how well it works.
Hefei, AnhuiAges 18 years+ - NCT06382844Recruiting
Better detection of tumor cells in cutaneous T-cell lymphoma
This study uses advanced blood tests (flow cytometry) to find cancer cells more accurately in people with cutaneous T-cell lymphoma. It could lead to better monitoring of your condition.
SalamancaAges 18 years+ - NCT06385977Recruiting
Risk Factors for Chronic Prostatitis in Northwest China
This study looks for risk factors in men from Northwest China with long-term pelvic or perineal pain (chronic prostatitis) compared to healthy volunteers.
Xi'an, ShaanxiAges 18 years+ - NCT06387329RecruitingPhase 4
Antibiotic to prevent UTI after bladder Botox
This study tests whether taking a low-dose antibiotic (nitrofurantoin) before a Botox bladder injection can help prevent urinary tract infections. You may be able to join if you are getting Botox for overactive bladder or painful bladder syndrome and do not have frequent UTIs or other health issues that would make the antibiotic unsafe.
Bethesda, MarylandAges 18 years+ - NCT06387823Recruiting
Testing Sivelestat Sodium and Dexamethasone for Severe ARDS
This trial tests a combination of two medicines (Sivelestat Sodium and Dexamethasone) to see if they can help people with severe lung injury (ARDS) who need a breathing machine. It is for patients whose condition has just worsened and who are on a ventilator early in their illness.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06388174Recruiting
Idiopathic Generalized Epilepsy Study
This study is looking at people with a specific type of epilepsy called idiopathic generalized epilepsy (IGE). The goal is to collect health information and use a 24-hour brain wave test to learn more about the condition.
Hangzhou, ZhejiangAges 4–40 - NCT06389474RecruitingPhase 3
Testing a new treatment for children with a serious kidney condition
This study tests a new medicine called INM004 in children with STEC-HUS, a serious illness that damages the kidneys and blood cells. It may help speed up recovery and prevent complications.
Bahía Blanca, Buenos AiresAges 9 months–17 years - NCT06394934Recruiting
Home blood pressure changes and artery health in hypertension
This study looks at how changes in home blood pressure readings over time relate to hardening of the arteries and metabolic problems in people with high blood pressure. If you take medication for high blood pressure and monitor your pressure at home, you may help researchers understand these connections better.
SeoulAges 19 years+ - NCT06395285RecruitingPhase 1
Testing DF-003 for ROSAH syndrome with eye inflammation
This trial tests an oral medication called DF-003 for people with ROSAH syndrome who have eye inflammation (uveitis). The goal is to see if the drug is safe and tolerable. It might help reduce eye inflammation and other symptoms.
Bethesda, MarylandAges 18–65 - NCT06397365Recruiting
Hypnosis for better CPAP use
This trial tests if hypnosis sessions can help people with sleep-disordered breathing use their CPAP machine more consistently, especially if they are currently using it less than 3 hours a night.
Lausanne, Canton of VaudAges 18 years+ - NCT06398457RecruitingEarly Phase 1
Darzalex Before Stem Cell Transplant for High-Risk Graft Failure
This trial tests giving a drug called Darzalex Faspro before the usual desensitization and a stem cell transplant for people at high risk of graft failure due to donor-specific antibodies. The goal is to prevent the transplant from failing.
Baltimore, MarylandAges 18 years+ - NCT06399952Recruiting
Natural history study for Baker Gordon syndrome
This study follows people with Baker Gordon syndrome over time to better understand the condition. Participants and their caregivers share medical records and complete tests and questionnaires.
Columbia, MissouriAges birth–99 years - NCT06402318Recruiting
Quick breath test for COVID, flu, and RSV
This study tests a breathalyzer device that quickly detects COVID-19, flu, and RSV from your breath. If you are already being tested for these viruses, you may join to see if this new method works as well as the usual swab test.
Fort Sam Houston, TexasAges 18–89 - NCT06403189Recruiting
Studying choroid plexus function in brain diseases
This study looks at how a part of the brain called the choroid plexus works in people with different brain conditions. It may help find better ways to diagnose or treat these diseases.
ParisAges 18 years+ - NCT06408662Recruiting
Remote mindfulness program for tics (Tourette or tic disorder)
This study tests a mindfulness program delivered remotely (via phone or tablet) to help people with moderate to severe tics. It aims to see if mindfulness can reduce tic severity and improve quality of life.
Baltimore, MarylandAges 18 years+ - NCT06410833RecruitingPhase 4
Combination therapy for resistant Sjögren's in children
This trial tests a combination of two medicines, rituximab then belimumab, for children and teens with Sjögren's syndrome that hasn't improved with other treatments. The goal is to see if this two-step approach can better control symptoms like joint pain, skin rashes, and blood problems.
Beijing, Beijing MunicipalityAges 5–18
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,173 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.