Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06112964Recruiting
Brain and behavior changes in cancer-related weight loss
This study looks at changes in thinking, behavior, and brain structure that can happen when people with cancer lose weight and appetite (called cachexia). Researchers will use questionnaires and brain scans to understand these changes, which may help improve care for people with cancer.
CambridgeAges 18 years+ - NCT06115122Recruiting
PEPPI Study: Finding early signs of placental problems in pregnancy
This study looks at blood markers to find women at risk for placental problems during pregnancy. It involves blood tests in early and late pregnancy, and at birth, to see how iron levels and other factors affect the placenta and baby's health.
OuluAges Any age - NCT06117579Recruiting
Breathing Muscle Training for Sleep Apnea
This trial tests whether a simple breathing exercise (training the muscles you use to breathe in) can improve sleep apnea symptoms in people who already use CPAP. The goal is to see if adding this training helps you feel better or need less CPAP pressure.
OrléansAges 18 years+ - NCT06123962Recruiting
Identifying lung injury subtypes to guide treatment
This study looks at different patterns in patients with a severe lung condition called ARDS, to better understand why some respond to treatments differently. You may help doctors learn how to personalize care.
BeijingAges 18 years+ - NCT06124586Recruiting
Early angioplasty for diabetic foot ulcers
This trial tests if an early procedure to open blocked leg arteries (angioplasty) helps heal foot ulcers in people with type 2 diabetes. It aims to improve blood flow and prevent amputation.
DüsseldorfAges 18 years+ - NCT06124599Recruiting
Early signs of menstrual toxic shock syndrome
This study looks at what happens in the days just before menstrual toxic shock syndrome starts. If you are a young woman who uses tampons or cups and recently got very sick with fever, rash, and low blood pressure during your period, you may be able to join as a case participant.
LyonAges 13–30 - NCT06128317Recruiting
Heart attack and chest pain registry study
This study is a registry that collects information from people who come to the hospital with heart-related symptoms like chest pain or high troponin levels. It helps doctors better understand different heart conditions and improve care.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT06130579RecruitingPhase 2
Interferon-α for TP53-mutated blood cancer after transplant
This trial tests whether a medicine called interferon-α can help people with a specific gene mutation (TP53) in their blood cancer after they've had a donor stem cell transplant. It aims to prevent the cancer from coming back.
Beijing, Beijing MunicipalityAges 12–65 - NCT06131658Recruiting
Functional training for iliotibial band syndrome in runners
This trial tests whether functional motor control exercises can reduce pain and improve flexibility and leg function in runners with IT band syndrome. It may help you run without pain on the outside of your knee.
Faisalābad, Punjab ProvinceAges 19–40 - NCT06132477RecruitingPhase 4
Study of GLP-1 medicines after weight loss surgery
This study looks at what happens when people taking a GLP-1 medication (like Ozempic) either stop or continue it after weight loss surgery. The goal is to learn whether staying on the medicine helps with long-term weight control.
Columbia, MissouriAges 18 years+ - NCT06133712Recruiting
Injection treatment for carpal tunnel pain
This trial tests whether a local injection of three medications (dexmedetomidine, ozone, and dexamethasone) can relieve pain and symptoms in people with mild-to-moderate carpal tunnel syndrome. It aims to provide a non-surgical option for those who haven't improved with other treatments.
Tanta, El GharbiaAges 20–60 - NCT06138587RecruitingPhase 1
NK cell therapy after stem cell transplant for high-risk blood cancers
This trial tests whether giving specially trained natural killer (NK) cells after a stem cell transplant can help prevent relapse in people with high-risk blood cancers like AML, MDS, or MDS/MPN. You receive one infusion of these cells about a week after your transplant.
Boston, MassachusettsAges 18 years+ - NCT06144593Recruiting
Carb cutting for people with type 2 diabetes
This study looks at whether cutting carbs on certain days can improve metabolism for people with type 2 diabetes. It may help if you have mild to moderate diabetes and are overweight or obese.
HvidovreAges 35–75 - NCT06146231Recruiting
Breast reconstruction with Motiva implants and fat grafting
This study tests a new breast reconstruction method using Motiva Flora implants and your own fat to rebuild the breast after a mastectomy. It is for women who need tissue expansion as part of their reconstruction and have completed cancer treatments at least one year earlier.
GhentAges 18 years+ - NCT06148818Recruiting
Neck exercises for jaw pain relief
This study tests whether special neck exercises can help reduce jaw pain in people who have both jaw (TMJ) problems and neck pain. If you have had jaw pain for at least 3 months and also have achy neck pain, you may be able to join.
TrabzonAges 18–55 - NCT06148467Recruiting
Understanding breathing patterns and adjusting ventilator support
This study looks at a specific breathing pattern called reverse triggering in people with ARDS (a serious lung condition) who are on a ventilator. The goal is to see how adjusting the ventilator settings affects this pattern and improves breathing coordination.
GuadalajaraAges 18–90 - NCT06154252RecruitingPhase 2/Phase 3
Study of CABA-201 for active myositis in adults and children
This trial tests a new treatment called CABA-201, which uses your own immune cells modified to attack the overactive cells causing myositis. It is for people with active disease that hasn't improved enough with standard therapies.
Orange, CaliforniaAges 6–75 - NCT06155708Recruiting
Ketone drink study for women with PCOS
This study tests if a special ketone drink can help women with polycystic ovary syndrome (PCOS). Researchers want to see if it improves health markers related to the condition.
Montreal, QuebecAges 18–40 - NCT06161805RecruitingPhase 3
Esketamine for chronic pain from endometriosis
This trial tests if esketamine, a nasal spray, can reduce chronic pelvic pain in women with endometriosis that hasn't improved with standard painkillers. You may qualify if you have severe pain and are scheduled for endometriosis surgery.
DelftAges 18–50 - NCT06161636Recruiting
Studying hand movement to diagnose Parkinson's early
This trial looks at how analyzing hand movements might help doctors tell the difference between Parkinson's disease and other similar conditions early on. It may help improve diagnosis so patients get the right care sooner.
Montreal, QuebecAges 50–75 - NCT06161701Recruiting
Steroid-related diabetes in kidney disease patients
This trial looks at how steroids affect blood sugar in people with certain kidney diseases. If you are starting steroid treatment, this study may help understand and manage the risk of developing diabetes.
Hangzhou, ZhejiangAges 18–75 - NCT06162013RecruitingPhase 2
NAD supplement trial for atypical parkinsonism
This trial tests whether a supplement called nicotinamide riboside (NR) can help people with rare forms of parkinsonism (PSP, MSA, or CBS). It is a double-blind study, meaning neither you nor the doctors will know if you are getting the real supplement or a placebo.
Oslo, OsloAges 30–85 - NCT06162247Recruiting
Registry study for heart patients in intensive care
This study tracks patients with sudden heart problems admitted to a special heart intensive care unit. It helps doctors learn more about these conditions to improve future care.
NaplesAges 18 years+ - NCT06163768Recruiting
Insulin's role in non-diabetic heart attack patients
This study looks at how insulin resistance affects recovery after a heart attack or unstable angina in people without diabetes. It may help understand why some patients have worse outcomes.
Ho Chi Minh City, FiveAges 18–60
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.