Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07085923Recruiting
Heart health study for people with mental illness
This study tests a program to improve heart health in people with schizophrenia or bipolar disorder who take antipsychotic medication or lithium and have a high body weight. The goal is to help reduce heart disease risk.
OsloAges 25–70 - NCT07090473Recruiting
Electrical stimulation for recent spinal cord injury recovery
This trial tests whether a mild electrical stimulation (called TENS) can help recovery after a recent spinal cord injury. It is for people who are already in the ICU with a drain in their lower back and had a blunt injury within the past 12 hours.
San Francisco, CaliforniaAges 21 years+ - NCT07086612Recruiting
Sleep apnea and dental crossbite in children
This study looks at the link between sleep apnea (pauses in breathing during sleep) and a narrow upper jaw (crossbite) in children ages 6 to 16. It may help understand if treating the jaw can improve sleep breathing.
RouenAges 6–16 - NCT07095426Recruiting
Fiber supplement study for gut and blood vessel health
This study tests whether taking a fiber supplement can improve gut health and blood vessel health in people with obesity. It may help you understand how your body responds to extra fiber.
Muncie, IndianaAges 18–55 - NCT07093905Recruiting
Comparing two anesthetics for rotator cuff repair surgery
This study compares two types of anesthesia (numbing medicine) for rotator cuff repair surgery. It will help find which method works better for pain control and recovery.
MarseilleAges 18 years+ - NCT07090551Recruiting
Mouthguard for jaw and neck muscle pain from grinding
This study tests whether a custom mouthguard (occlusal splint) can reduce pain and tension in the jaw and neck muscles. It is for people with bruxism (teeth grinding) and myofascial pain, a type of muscle pain in the jaw area.
IstanbulAges 18–50 - NCT07087587Recruiting
Sleep apnea treatment for AFib: a personalized trial
This study tests whether treating sleep apnea with a CPAP machine can reduce the number of AFib episodes you have. It's a personalized 'N-of-1' trial, meaning you'll try both CPAP and no CPAP at different times to see what works best for you.
Cleveland, OhioAges 18–85 - NCT03994874RecruitingPhase 1/Phase 2
Testing fluid removal through the belly in heart-kidney failure
This trial studies a treatment that removes extra fluid through a catheter placed in the abdomen (peritoneal ultrafiltration) for people with “cardio-renal syndrome” (heart and kidney problems together). It may help those who stay congested despite high-dose water pills (diuretics) and have certain heart circulation and fluid signs.
ChietiAges 18 years+ - NCT05650905Recruiting
Eye and blood-vessel function study after COVID-19
This study measures how well the nerves in your retina and the tiny blood vessels in your eye “couple” (work together) after COVID-19. It may help researchers understand eye-related effects of COVID-19 and long COVID, and how these processes change over time.
Vienna, State of ViennaAges 18 years+ - NCT06353607Recruiting
Genetics of aortic aneurysm and dissection
This study looks at the genetic reasons behind aortic aneurysms and sudden aortic tears. By studying people who had surgery at the University Hospital Basel, researchers hope to find inherited patterns that could help predict and prevent these serious conditions.
BaselAges 18 years+ - NCT06512168Recruiting
Measuring aided language development in children
This study tests whether using an iPad communication app helps children with Down syndrome or cerebral palsy who have trouble speaking. It looks at how their language skills grow over time.
Orlando, FloridaAges 3.5 years–5 years - NCT07079137Recruiting
Snakebite severity score study
This study tests a new scoring system to predict how serious a snakebite is and what symptoms may develop. If you've been bitten by a snake in the last 24 hours, this study could help improve care for others like you.
Thrissur, KeralaAges 18 years+ - NCT07083713Enrolling by invitation
Group coaching for life goals with chronic conditions
This study tests if group coaching helps people with certain chronic conditions set and achieve life goals. You would join phone or video sessions with a coach and others like you.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07083973Recruiting
Monitoring lung function with 3D imaging in ARDS
This study is testing a new way to monitor lung function using a 3D electrical imaging device (EIT) while patients with ARDS lie on their stomach to improve breathing. The goal is to see if this imaging helps doctors better understand how the lungs are working.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07081412Recruiting
Home-based nerve stimulation for overactive bladder
This trial tests if a nerve stimulation treatment, usually done in a clinic, can be done at home using a mobile app. It aims to help women with overactive bladder symptoms like sudden urges to urinate.
Izmir, İzmirAges 18 years+ - NCT07077057Recruiting
AI tool for heart attack detection
This trial tests an artificial intelligence system that helps doctors quickly identify heart attacks (myocardial infarction) in patients with symptoms like chest pain or shortness of breath. It aims to speed up diagnosis and treatment.
Lugano, Canton TicinoAges 18 years+ - NCT07084714Recruiting
Can moderate exercise help with period symptoms?
This trial tests whether moderate aerobic exercise can help manage menstrual cycle symptoms in people who are not very active. You would exercise for a few weeks while tracking your symptoms to see if exercise makes a difference.
Colorado Springs, ColoradoAges 18–40 - NCT07085676RecruitingPhase 1
CAR-T cell therapy for autoimmune diseases that resist treatment
This study tests a new cell therapy called CAR-T (using your own immune cells) for people with severe autoimmune diseases like lupus, scleroderma, or myositis that have not improved with standard treatments. The goal is to see if it can safely reduce disease activity.
JerusalemAges 18–80 - NCT07082972RecruitingPhase 4
Study of splint therapy and Botox for jaw muscle pain
This trial compares two treatments—a dental splint and Botox injections into the jaw muscle (masseter)—to see which one better relaxes head and neck muscles in people with myofascial pain syndrome. It may help you if you have facial pain related to muscle tension.
Istanbul, VeznecilerAges 18–55 - NCT04460859Recruiting
Testing an electrical monitor in moderately severe lung failure
This trial tests a bedside breathing and lung-monitoring method that uses small electrodes on the chest. It is meant for people with moderate to severe ARDS (a serious lung inflammation problem) who are on a breathing machine, to help guide care.
São PauloAges 18 years+ - NCT06962202Recruiting
Modified Desmopressin PET/CT for Cushing's Syndrome
This trial tests a new way to use a medicine called desmopressin with a special type of imaging (PET/CT) to help find cortisol-producing tumors in people with Cushing's syndrome. It may help doctors better locate the problem without needing as much radiation.
ChandigarhAges 5–75 - NCT05305482Recruiting
Compare two stents after heart attack treatment
This trial compares two types of stents that release medicine to help keep arteries open after an acute coronary syndrome event (often called a heart attack or unstable angina). It tests whether the standard short course of two blood-thinning medicines for one month is enough, and which stent strategy works best.
SeoulAges 19 years+ - NCT06979427Recruiting
Predicting heart artery blockages with CT and FFR
This study tests whether a CT scan combined with blood-flow measurements can better predict which heart artery blockages are serious. It may help avoid unnecessary invasive tests.
Shiraz, FarsAges 20–80 - NCT06203405Recruiting
Sedation guided by breathing effort in ICU patients
This trial tests a new way to manage sedation (medication to keep you calm and comfortable) for people on a breathing machine. The goal is to see if adjusting sedation based on your breathing effort leads to better outcomes and shorter time on the machine.
Bangkok, BangkokAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.