Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,173 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06411028RecruitingPhase 4
Studying botulinum toxin for arm tremor in dystonia
This study looks at whether botulinum toxin (Botox) injections can help reduce arm tremors in people with dystonia. Researchers hope to understand which patients benefit most.
Nijmegen, GelderlandAges 18 years+ - NCT06412536Recruiting
Heart, weight, and hormone trial screening survey
This trial is a quick survey to find out if you may be eligible for future studies on heart health, weight, or hormone-related conditions. It helps researchers match you with the right treatment options.
Brooklyn, New YorkAges 18 years+ - NCT06414096RecruitingPhase 1
Can a fertility drug help women with obesity get pregnant?
This study tests if a special way of giving a fertility drug (FSH) can improve pregnancy chances in women with obesity who are having trouble conceiving. It aims to understand how the drug affects reproductive health.
Aurora, ColoradoAges 19–37 - NCT06416488Recruiting
HIIT for heart health in school-age kids
This trial tests whether a high-intensity interval training (HIIT) program can improve heart health and reduce risk factors like high blood sugar, cholesterol, and blood pressure in school-age children. It's for children who have at least one of these problems and are not already doing intense exercise.
Shanghai, Shanghai MunicipalityAges 7–18 - NCT06421818RecruitingPhase 2
Baitouweng Decoction for ulcerative colitis with damp-heat
This trial tests a traditional Chinese herbal formula called Baitouweng Decoction for people with mild to moderate ulcerative colitis who also have a specific pattern of symptoms called 'damp-heat' in the large intestine. It aims to see if the medicine can help reduce inflammation and improve symptoms.
Nanjing, JiangsuAges Any age - NCT06427694Recruiting
Long-Term Follow-Up of Low-Dose IL-2 After Heart Attack
This study is checking on people who finished a previous trial (IVORY) that tested a low-dose treatment called IL-2 for reducing inflammation after a heart attack. It will see how they are doing over time and if the treatment helped their heart health.
Cambridge, CambridgeshireAges 18–85 - NCT06428019RecruitingPhase 3
Comparing drug combinations for untreated CLL or SLL
This trial tests two different drug combinations (venetoclax with obinutuzumab or with acalabrutinib) to see how they affect the risk of tumor lysis syndrome in people with untreated CLL or SLL. It may help find the safest and most effective way to start treatment.
Tucson, ArizonaAges 18 years+ - NCT06428188RecruitingPhase 1/Phase 2
CAR-T cells targeting BCMA/CD19 for autoimmune diseases
This trial tests a new treatment called CAR-T cells that target two proteins (BCMA and CD19) on immune cells. It is for people with certain autoimmune diseases that have not improved with standard treatments.
Beijing, Beijing MunicipalityAges 21–90 - NCT06430528Recruiting
Osilodrostat and steroid replacement for Cushing syndrome
This trial tests a new approach, called 'block-and-replace', for treating Cushing syndrome. You will take osilodrostat to lower high cortisol levels, along with a glucocorticoid (a steroid) to replace what your body needs. This study may help control the disease if surgery hasn't worked or isn't an option.
Ann Arbor, MichiganAges 18–75 - NCT06436092Recruiting
Stent treatment for left main coronary artery disease
This trial studies a new way to treat blockages in the left main coronary artery using a drug-coated stent. It aims to find out if a careful approach with a single stent and temporary side-branch support works well for people with heart disease.
Ichinomiya, Aichi-kenAges 18 years+ - NCT06439199Recruiting
Blood protein study in non-intensive chemotherapy for AML and MDS
This study looks at certain proteins in the blood (called FLT3 ligand and IL6) of people being treated for blood cancers like AML, MDS, or CMML. The goal is to understand how these proteins change during non-intensive chemotherapy, which may help doctors better personalize treatment.
Nantes, Loire-AtlantiqueAges 18–99 - NCT06440070Recruiting
Ultrasound-guided needle thread release for carpal tunnel
This trial tests a new, less invasive way to release the tight ligament in the wrist that causes carpal tunnel syndrome. It uses ultrasound to guide a curved needle and thread to cut the ligament, which may lead to less pain and faster recovery.
Guangzhou, GuangdongAges 40–70 - NCT06444321Recruiting
Integrated care for frail patients with heart failure
This trial tests a special care program for people with both frailty (being weak or vulnerable) and heart failure (when the heart doesn't pump well). The program brings together different types of support to help you manage your health better after a hospital stay.
Drammen, AkershusAges 18 years+ - NCT06446947Recruiting
Blood markers for poor outcomes after sepsis in cancer surgery
This study looks at blood markers (epigenetics) to better understand why some people have a harder time recovering from a severe infection after major cancer surgery. The goal is to find early signs of poor outcomes in men aged 45–75 with post-surgery sepsis.
Marseille, Bouches du RhôneAges 45–75 - NCT06449274Recruiting
Imaging study for heart artery blockages after stenting
This trial uses special imaging (OCT or IVUS) to look at other blockages in your heart arteries that weren't treated during your stent procedure. It helps doctors decide if those blockages might need treatment later.
Harbin, HeilongjiangAges 18–80 - NCT06450301Recruiting
Studying aging cells in thin uterine lining
This study is looking at aging cells in the lining of the uterus in women who have a thin endometrial lining. It aims to understand what causes this problem and how to improve fertility treatment.
Toronto, OntarioAges 18–39 - NCT06450327Recruiting
Resistant Hypertension: A Complex Condition Study
This study looks at why some people with hard-to-control high blood pressure (resistant hypertension) may also have other health problems. It aims to better understand the condition and how to help patients like you.
Votuporanga, São PauloAges 18–85 - NCT06451198RecruitingPhase 4
Indobufen vs aspirin after stent in older heart patients
This trial tests whether a blood thinner called indobufen works as well as aspirin for older people (65+) who have had a heart attack or unstable angina, received a drug-eluting stent, and are already taking two blood thinners. The goal is to find a safer or better option for long-term prevention.
Shanghai, Shanghai MunicipalityAges 65 years+ - NCT06453499Recruiting
Silent Lower Back Disc Herniation Study
This study looks at people who have a herniated disc in their lower back that is pressing on a nerve, but who have no back pain or leg pain. The goal is to understand this 'silent' condition and why some people have no symptoms.
GizaAges 20–40 - NCT06453447Recruiting
Prednisone to prevent CRPS after wrist fracture surgery
This trial tests whether a short course of the steroid prednisone can prevent or reduce complex regional pain syndrome (CRPS) after wrist surgery. It is for people who had a broken wrist fixed with a plate and screws and have a higher chance of developing CRPS.
Vancouver, British ColumbiaAges 19 years+ - NCT06456502Recruiting
Non-invasive brain stimulation for long COVID symptoms
This trial tests whether a gentle, non-invasive brain stimulation device can help relieve long COVID symptoms. It involves wearing special gloves and socks that deliver mild electrical pulses to improve how you feel.
Alcorcón, MadridAges 18 years+ - NCT06458374Recruiting
Heart Amyloidosis in Carpal Tunnel Surgery Patients
This study looks for people who had carpal tunnel surgery at Ålesund Hospital to check for a rare heart condition called ATTR amyloidosis. It aims to find the disease early and see how common it is.
Ålesund, Møre og RomsdalAges 50 years+ - NCT06462287RecruitingPhase 2
Testing a substance P blocker for high blood pressure and sleep apnea
This study tests if a drug that blocks substance P can lower a hormone called aldosterone in people with both severe sleep apnea and high blood pressure. If you have these conditions, this trial may help find a new treatment option.
Rouen, FranceAges 18–75 - NCT06462365RecruitingPhase 1
Preventing GvHD after stem cell transplant for blood cancers
This trial tests a new way to prevent graft-versus-host disease (GvHD), a common complication after a stem cell transplant. It is for people with certain blood cancers who are getting a stem cell transplant from a half-matched family member or unrelated donor.
Duarte, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,173 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.