Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07013903Recruiting
Hydrotherapy for post-COVID recovery
This trial tests if Kneipp hydrotherapy (a type of water treatment) helps people recover from post-COVID syndrome. You would receive this therapy during a rehabilitation stay and answer questions on your smartphone.
Schönau am Königssee, BavariaAges 18 years+ - NCT07019519Recruiting
Gut hormones and blood flow in POTS
This study looks at how gut hormones control blood flow after eating in people with POTS. It may help explain symptoms like dizziness and rapid heartbeat after meals.
CopenhagenAges 18–50 - NCT07020858Recruiting
FAPI imaging for heart attack risk in blocked arteries
This trial tests whether a special scan called FAPI-PET can predict heart problems in people with a chronic total occlusion (a completely blocked heart artery for at least 3 months). If you have this type of blockage and are planning to have a procedure to open it, this study may help guide your care.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07019857Recruiting
Thymus removal and immunity in infant heart surgery
This study looks at how removing the thymus gland during infant heart surgery affects the immune system. It compares babies who have their thymus removed with those who have heart surgery without removing it, and with babies having other types of surgery.
NantesAges Up to 6 months - NCT07018960Recruiting
Chest wall repair with custom 3D-printed titanium implant
This study is testing a new way to repair large chest wall defects using a custom-made 3D-printed titanium implant. It may help people who need chest wall reconstruction after cancer surgery, a bad injury, or damage from infection or radiation.
Cruces, Basque CountryAges 18 years+ - NCT04802707RecruitingPhase 2
Study drug for mitochondrial depletion disorder due to gene changes
This Phase 2 trial tests a treatment made from deoxynucleosides to help people with mitochondrial depletion disorder caused by certain gene changes. If you match the genetic diagnosis, the study may see whether the treatment improves symptoms or disease markers.
Montreal, QuebecAges 1 month–60 years - NCT07006025RecruitingPhase 1
Oral THU-decitabine for MDS that has returned or not improved
This trial tests an oral combination of two drugs (THU and decitabine) for people with myelodysplastic syndromes (MDS) whose disease has come back or not responded to at least one prior standard treatment. The goal is to see if it can help control the disease.
The Bronx, New YorkAges 18 years+ - NCT07009691Recruiting
Hydrogen water for ME/CFS patients
This trial tests whether drinking hydrogen-rich water can improve heart rate variability (a measure of nervous system function) in people with ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome). The goal is to see if this simple intervention helps reduce symptoms.
Stony Brook, New YorkAges 18–65 - NCT07010328Recruiting
AI-guided posture training for Parkinson's disease
This trial tests whether a special training program that uses artificial intelligence can help improve posture in people with Parkinson's disease who have a forward bend or lean to one side. If you have Parkinson's and a noticeable postural problem, this might be a way to try a new approach to rehabilitation.
Pavullo nel Frignano, PaviaAges 18 years+ - NCT07008989Recruiting
Phone app to improve memory in Down syndrome
This study tests a smartphone app called HippoCamera to see if it can help teenagers and young adults with Down syndrome remember everyday events better. You would use the app at home with some help from a parent or guardian.
Chestnut Hill, MassachusettsAges 15–35 - NCT07010250Recruiting
Kidney Energy Use and Scarring in ANCA Vasculitis
This study looks at how kidney cells use energy and how that leads to scarring in people with ANCA vasculitis. It compares findings with people who have other kidney diseases to better understand and possibly treat kidney damage.
ParisAges 18–90 - NCT07013344Recruiting
Link between NT-proBNP and heart artery disease
This study looks at a blood test called NT-proBNP to see if it can help predict how much blockage is in the heart's arteries. It may help doctors better understand heart disease risk.
Milan, ItalyAges 18 years+ - NCT07008365RecruitingPhase 3
Measuring belly pressure and ultrasound to guide fluid removal in heart failure
This trial tests whether using belly pressure and bedside ultrasound can help doctors better manage fluid removal (decongestion) in people hospitalized with heart failure. The goal is to see if this approach leads to better outcomes.
ZaragozaAges 18–100 - NCT06130579RecruitingPhase 2
Interferon-α for TP53-mutated blood cancer after transplant
This trial tests whether a medicine called interferon-α can help people with a specific gene mutation (TP53) in their blood cancer after they've had a donor stem cell transplant. It aims to prevent the cancer from coming back.
Beijing, Beijing MunicipalityAges 12–65 - NCT06994676RecruitingPhase 1
Study of CBX-250 for advanced myeloid leukemias
This study tests an experimental drug, CBX-250, for people with certain advanced blood cancers (like AML) that have not responded to standard treatments or have returned. The drug works only for people who have a specific genetic marker (HLA-A*02:01). The goal is to see if it is safe and how well it works.
Duarte, CaliforniaAges 12 years+ - NCT07001891Recruiting
Brain activity study for restless legs syndrome
This study looks at brain connections related to body awareness in people with restless legs syndrome (RLS). It may help researchers understand RLS better.
BordeauxAges 18–70 - NCT07000227Recruiting
Low FODMAP diet study for IBS or functional dyspepsia
This study looks at how a low FODMAP diet affects people with irritable bowel syndrome (IBS) or functional dyspepsia (FD). It aims to understand why this diet helps some patients and may offer a way to manage your symptoms.
Kuala Lumpur, Kuala LumpurAges 18 years+ - NCT06996119RecruitingPhase 1
Preventing graft-versus-host disease after stem cell transplant
This trial tests adding a drug called emapalumab to standard medications (cyclophosphamide, tacrolimus, mycophenolate mofetil) to prevent graft-versus-host disease in adults receiving a donor stem cell transplant. This approach aims to reduce complications after transplant.
Duarte, CaliforniaAges 18–75 - NCT07002710Recruiting
Long-term ventilation and inflammation study
This study looks at how long-term inflammation affects the breathing of people who have been on a ventilator for 10 days or more. It aims to help doctors better understand and support your recovery.
TaipeiAges 20 years+ - NCT06721884RecruitingPhase 1/Phase 2
Artemisia annua for small intestinal bacterial overgrowth (SIBO)
This trial tests whether a supplement made from Artemisia annua (sweet wormwood) can help people with SIBO, a gut condition. You will take the supplement or a placebo for 5 weeks and have breath tests and blood draws to see how it affects your symptoms.
Portland, OregonAges 18 years+ - NCT06991114RecruitingPhase 2
AlloNK and rituximab for relapsing rheumatologic diseases
This trial tests a new natural killer (NK) cell therapy called AlloNK given with rituximab for people with certain autoimmune diseases (rheumatoid arthritis, Sjögren's disease, inflammatory myopathies, or systemic sclerosis) that have not responded well to standard treatments. The goal is to see if this combination can better control the disease.
Tuscaloosa, AlabamaAges 18 years+ - NCT06987058Enrolling by invitationPhase 2
Continued RVU120 treatment study for current participants
This trial is for people who are already in a RVU120 study and have been receiving the drug for at least 5 cycles. It allows you to keep getting RVU120 if you are benefiting from it and don't have other treatment options.
NiceAges 18 years+ - NCT06983028RecruitingPhase 2
Testing atacicept for multiple kidney diseases
This trial tests a medicine called atacicept in adults and children with several types of kidney disease. The goal is to see if it can reduce protein in the urine and help protect kidney function.
Brisbane, CaliforniaAges 2 years+ - NCT06990477Recruiting
EIT-guided breathing machine settings for ARDS
This trial tests a special monitoring technique called EIT (electrical impedance tomography) to help doctors set the best breathing machine pressure for people with ARDS. It may help improve oxygen levels and protect the lungs.
Hefei, AnhuiAges 19–90
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.