Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,173 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06464042Recruiting
Air Quality and Early Heart Disease Study
This trial studies how air quality affects early heart disease in young adults aged 18 to 40. It looks at people in Galicia, Spain, who already have coronary artery disease and compares them to healthy individuals.
Vigo, PontevedraAges 18–40 - NCT06465160RecruitingPhase 1
Study of MNV-201 for low-risk MDS with anemia
This study tests a new therapy called MNV-201 for people with low-risk myelodysplastic syndromes (MDS) who have anemia and need regular blood transfusions. The goal is to see if this treatment can help reduce or stop the need for transfusions.
Jerusalem, IsraelAges 18–100 - NCT06468774Recruiting
Test for gut ischemia in chronic belly artery disease
This study tests a blood marker for chronic mesenteric ischemia (poor blood flow to the gut). If it works, it could help doctors diagnose the condition faster and more easily.
Oslo, OsloAges 18 years+ - NCT06469437Recruiting
Geriatric check for older adults with type 2 diabetes
This study looks at how a full health check for older adults with type 2 diabetes can help doctors choose the best treatment plan. It aims to improve care for people 60 and older.
Porto Alegre, Rio Grande do SulAges 60 years+ - NCT06469632Recruiting
Radiofrequency for pelvic pain after first vaginal birth
This trial tests whether a non-surgical treatment called radiofrequency can help relieve pelvic pain that starts after a first vaginal birth. The study focuses on a type of muscle pain called myofascial pain syndrome.
Alcalá de Henares, MadridAges 18–45 - NCT06471374Recruiting
Circadian rhythm in delayed sleep-wake phase disorder
This study looks at how your body's internal clock works in people with delayed sleep-wake phase disorder, especially those living at high altitudes. It aims to understand the causes of this sleep problem and may help find better treatments.
Boulder, ColoradoAges 16–40 - NCT06471751Recruiting
Muscle training for moderate sleep apnea
This trial tests whether a 3-month program of muscle exercises for breathing and mouth strengthens the airway, to help people with moderate sleep apnea breathe better during sleep and possibly reduce their symptoms.
GrenobleAges 18 years+ - NCT06472622RecruitingEarly Phase 1
Brain imaging study of pain and effort
This study uses brain scans to understand how people experience pain and effort. It compares healthy volunteers to people with ME/CFS to see if there are differences in brain activity.
Bethesda, MarylandAges 18–50 - NCT06473142Recruiting
Body posture and shoulder pain study
This study looks at how your body posture might be related to shoulder pain. It is for people with shoulder impingement (pain when lifting the arm) who are not athletes. The goal is to understand if posture plays a role in shoulder problems.
CairoAges 20–40 - NCT06473844Recruiting
SGLT2 inhibitors for adults with sepsis
This trial tests whether a type of diabetes medicine (SGLT2 inhibitors) can help adults with sepsis, a life-threatening response to infection. If you have new-onset sepsis and can take oral medicine, you may be eligible.
Hong Kong, Hong KongAges 18 years+ - NCT06477549RecruitingPhase 2
Comparing Two Drug Combinations for Stem Cell Transplant
This study compares two different drug combinations (BeFluBu and FluBuRux) used before a stem cell transplant from a half-matched (haploidentical) donor. The goal is to see which combination works better to prepare your body for the transplant and control your blood cancer.
Saint PetersburgAges 18–75 - NCT06477861Recruiting
Elastic power predicts ARDS severity and death risk
This study looks at a new way to predict how serious ARDS (a severe lung injury from pneumonia) is and the chance of death. Doctors will measure something called "elastic power" to see if it helps guide treatment for patients on a breathing machine.
Banhā, Al QalubeyahAges 18–65 - NCT06480786Recruiting
Spinal cord stimulator for diabetic nerve and artery pain
This study tests if a spinal cord stimulator (a device that sends mild electrical pulses to the spine) can relieve severe leg pain caused by diabetic nerve damage and poor blood flow. It may help people who have not found enough relief from other treatments.
Omaha, NebraskaAges 19–89 - NCT06481943Recruiting
Testing a new heart scan for blocked arteries
This study tests a new magnetic heart scan (MCG) to see if it can better detect blocked arteries causing chest pain or heart attacks. It may help doctors decide the best treatment for you.
Rochester, MinnesotaAges 18 years+ - NCT05027945RecruitingPhase 2
Stem cell transplant for people with VEXAS syndrome
This Phase 2 trial tests whether an allogeneic stem cell transplant (from a donor) can treat VEXAS syndrome. It may help calm the body’s overactive inflammation and improve symptoms in eligible adults.
Bethesda, MarylandAges 18–75 - NCT06332859Recruiting
Resilience training for heart recovery
This study tests a resilience training program (a way to build mental strength and coping skills) for people recovering from certain heart conditions. It aims to help you feel better and manage stress, which is important for heart health.
Bad Tatzmannsdorf, BurgenlandAges 18 years+ - NCT07309783Recruiting
Lung imaging to guide breathing support in ARDS
This trial uses a special lung imaging technique (EIT) to guide ventilator settings for people with ARDS. It may help improve breathing support and reduce lung injury.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06880016Recruiting
Lung ultrasound after surfactant in preterm babies
This study uses lung ultrasound to see how different ways of giving surfactant (a medicine for breathing problems) affect preterm babies born before 32 weeks. It may help doctors choose the best method for your baby.
Konya, KaratayAges 1 day–5 days - NCT07421167RecruitingPhase 2
Ianalumab with TPO-RA for immune thrombocytopenia
This trial tests a new drug called ianalumab combined with a standard platelet-boosting medicine (TPO-RA) for adults with immune thrombocytopenia (ITP) or Evans syndrome. The goal is to see if the combination is well-tolerated and helps raise platelet counts.
Stamford, ConnecticutAges 18 years+ - NCT06486233Recruiting
Early invasive treatment for elderly heart attack patients
This trial tests whether early invasive treatment (like stenting) is safe and effective for patients 60 or older who have a certain type of heart attack called high-risk non-ST-segment elevation acute coronary syndrome. The goal is to see if this approach improves outcomes for older adults.
Ho Chi Minh CityAges 60 years+ - NCT06487247Recruiting
Home transfusion program for blood cancer patients
This trial offers red blood cell or platelet transfusions at home for people with blood cancer who are no longer responding to treatment. It aims to improve comfort and quality of life by avoiding hospital visits.
Boston, MassachusettsAges 18 years+ - NCT06492798RecruitingPhase 1/Phase 2
Stem cells for Long COVID: a safety and effectiveness study
This study tests whether a single infusion of mesenchymal stem cells can help with Long COVID symptoms—without causing serious side effects. It’s for people who are still struggling with COVID-related health problems months after their initial infection.
ShanghaiAges 18–70 - NCT06495177Recruiting
Survey on heart disease and diabetes prevention
This survey studies how well heart disease, diabetes, and kidney disease are being prevented and managed across Europe. If you've had a heart event or are taking medicines for high blood pressure, cholesterol, or diabetes, this study wants to learn from your experience.
IstanbulAges 18 years+ - NCT06497153Recruiting
Lung ultrasound for children with sickle cell disease
This study tests whether using lung ultrasound can help doctors quickly spot and treat acute chest syndrome in children with sickle cell disease. It may lead to faster, safer care for kids in the intensive care unit.
ParisAges 1 month–17 years
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,173 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.