Clinical trials
Drug Use Disorders clinical trials
Below are recruiting drug use disorders clinical trials, each written for real people, not researchers. We’re tracking 290 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07480525Recruiting
Escitalopram for first-time depression
This trial tests whether escitalopram, a common antidepressant, helps people who are experiencing their first episode of depression and have never taken medication for it. It also looks at how the drug works in the brain.
Beijing, Beijing MunicipalityAges 18–65 - NCT04065438Recruiting
Study of a blood-filter treatment for FSGS not responding to meds
This study looks at how well a specialized blood-filter device (the LIPOSORBER® LA-15) works for people with primary FSGS—especially when standard steroid and other medicines don’t work or can’t be tolerated. It may help reduce disease activity, particularly in people with kidney function that is still moderate or in those after kidney transplant.
Loma Linda, CaliforniaAges Up to 75 years - NCT05951660Recruiting
Study sexual side effects in schizophrenia with diabetes
This study looks at how sexual functioning is affected in people with schizophrenia, especially in those who also have diabetes or weight-related risk. It also examines how psychiatric medicines and diabetes/weight factors may be connected, which could help improve care for patients.
SlagelseAges 18 years+ - NCT06726590Recruiting
Gene testing for better medication outcomes
This study collects blood, urine, and cheek swabs, along with health information, to see how your genes affect your response to medications. You may be eligible if you take many medications or are on blood pressure or depression medication.
Bryan, TexasAges 18 years+ - NCT06388707RecruitingPhase 1/Phase 2
Ultrasound brain stimulation for drug-resistant epilepsy
This trial tests a low-intensity focused ultrasound device that aims to calm overactive brain areas causing seizures. It's for people whose seizures are not controlled by medication.
Palo Alto, CaliforniaAges 18 years+ - NCT06373016Recruiting
Ketone drink study for stable bipolar disorder
This study tests whether a ketone drink can change how the body uses energy in people with bipolar disorder. It may help understand new ways to manage the condition.
Belmont, MassachusettsAges 18–45 - NCT05658796Recruiting
Program to reduce opioid use after hip or knee replacement
This trial tests a support program called RXWell to help people use less opioid pain medicine after elective hip or knee replacement surgery. It may help by addressing anxiety and depression symptoms that can affect pain and recovery.
Monroeville, PennsylvaniaAges 18–100 - NCT07330349Recruiting
Trauma and substance use in penetrating abdominal injury
This study looks at alcohol, drug use, and painkiller use in people with a penetrating abdominal injury (like a stab or gunshot wound to the belly). It aims to understand how these substances affect patient outcomes.
Cali, Valle del Cauca DepartmentAges 15 years+ - NCT06639061RecruitingPhase 2
Brain stimulation to reduce PTSD flashbacks
This study tests whether a non-invasive brain stimulation technique called TMS can help reduce intrusive memories in people with PTSD. It uses MRI to guide the stimulation, and you will be randomly assigned to receive either active TMS or a placebo-like treatment.
Tel AvivAges 20–65 - NCT07680842Recruiting
Non-invasive ultrasound for drug-resistant epilepsy
This study tests a non-invasive focused ultrasound treatment for people with epilepsy that doesn't respond to medications. The goal is to see if this gentle ultrasound can reduce seizures without surgery.
San Francisco, CaliforniaAges 21–65 - NCT05267808Recruiting
Using sleep study patterns to guide future OSA treatment
This study looks at results from a sleep test to better understand the different types (“endotypes”) of obstructive sleep apnea. Your information may help doctors choose the next best step—often a procedure called drug-induced sleep endoscopy (DISE)—to guide treatment.
EdegemAges 18 years+ - NCT05510401Recruiting
Safe use study of an at-bed safety mattress system
This study checks whether a special bed-safety device (SÉCURIDRAP® SELFIA®) can be used safely for adults who get confused, move at night, or are at risk of falling out of bed. You may be able to join if you already have a prescription for the device and meet other safety and consent requirements.
BailleulAges 18 years+ - NCT05929144Recruiting
MRI testing to improve brain scans in neurodegenerative diseases
This study aims to improve MRI scan settings used when studying brain diseases that affect memory and movement. You would be asked to undergo MRI scanning as a healthy volunteer to help optimize the imaging process.
CaenAges 18 years+ - NCT07556692Recruiting
Home Brain Stimulation for Bipolar Depression
This study tests whether a device you use at home can help reduce depression symptoms in people with bipolar disorder. The device uses gentle electrical stimulation on the scalp to potentially improve mood.
LondonAges 18 years+ - NCT06788119Recruiting
Smartphone tool for facing fears in anxiety
This study tests a smartphone tool called SYMPTOMS-JIT to help people with anxiety disorders face their fears in real life. It might be a good option if you have a specific phobia, agoraphobia, panic disorder, or social phobia and want to try a new, guided approach.
Castellon, CastellónAges 18 years+ - NCT06544226Recruiting
Using smart devices to track eating disorder recovery
This study tests whether smart devices can help monitor recovery in people with eating disorders. You will use a device to track health signs and attend weekly clinic visits.
LiverpoolAges 10 years+ - NCT03816345RecruitingPhase 1
Nivolumab for advanced cancer with autoimmune conditions
This Phase 1 study tests nivolumab, an immunotherapy “anti-cancer accelerator,” in people with advanced cancer who also have an autoimmune disorder. It aims to see if nivolumab can be given safely and whether it may help shrink or control cancer.
Birmingham, AlabamaAges 18 years+ - NCT06732414Recruiting
Long-term study of multiple allergic diseases
This study creates a biorepository to collect and store samples (blood, nasal fluid, skin swabs) from people with allergies, asthma, sinus disorders, or immune dysregulation. It aims to better understand these conditions over time, which may help develop better treatments.
Bethesda, MarylandAges 3–100 - NCT07264803RecruitingPhase 2
Tumor testing to guide treatment for advanced cancers
This trial uses a patient's own tumor tissue to test which drugs might work best for cancers that have returned or not responded to previous treatments. It focuses on advanced gastric cancer and other solid tumors.
Jinan, ShandongAges 18–75 - NCT07280065RecruitingPhase 3
Testing a smartphone tool for PTSD diagnosis
This study tests a new tool (Senseye) that uses an iPhone camera to help diagnose PTSD. You will have a few video visits and answer questions about your mood and experiences.
Aurora, ColoradoAges 18 years+ - NCT07164040Recruiting
Study of Glow800 device during brain or reconstructive surgery
This study tests the GLOW800 device which uses a special dye (ICG) to help surgeons see blood flow during brain or reconstructive surgery. It aims to confirm the device works as intended.
PortoAges 18 years+ - NCT03781765RecruitingPhase 4
Testing stimulant vs non-stimulant ADHD treatments in young kids
This study compares stimulant and non-stimulant ADHD medicines in kids who have not taken ADHD medication before. It also studies how these treatments affect brain “reward” processes, which may be linked to substance-use risk.
New York, New YorkAges 7–12 - NCT06924008Recruiting
Eye contact therapy for adults with autism
This study tests a new program to help adults with autism feel more comfortable using eye contact. It is for people who are already getting treatment at a specialized autism center in the Netherlands.
Deventer, OverijsselAges 18–65 - NCT06048172Recruiting
Trauma therapy for PTSD with a psychotic disorder
This trial tests if prolonged exposure therapy, a common PTSD treatment, can help people who also have a psychotic disorder (like schizophrenia or bipolar with psychosis). The goal is to reduce PTSD symptoms.
HamburgAges 18 years+
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Common questions
- Are there clinical trials for drug use disorders?
- Yes. Clin2 currently lists 290 recruiting drug use disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a drug use disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a drug use disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.