Clinical trials
Drug Use Disorders clinical trials
Below are recruiting drug use disorders clinical trials, each written for real people, not researchers. We’re tracking 291 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06048172Recruiting
Trauma therapy for PTSD with a psychotic disorder
This trial tests if prolonged exposure therapy, a common PTSD treatment, can help people who also have a psychotic disorder (like schizophrenia or bipolar with psychosis). The goal is to reduce PTSD symptoms.
HamburgAges 18 years+ - NCT06638710RecruitingPhase 2
Testing oral midazolam for care in elderly with dementia who refuse care
This trial tests if giving a medication called midazolam by mouth can help older adults with memory problems who refuse care to accept it more calmly. It is for people in certain hospital or long-term care units, with moderate to severe memory loss and a history of resisting care.
Grenoble, IsereAges 60 years+ - NCT07143266Recruiting
Sleep study for people with pituitary and hypothalamus conditions
This study looks at sleep problems in people whose hypothalamus or pituitary gland does not work normally. It compares their sleep with healthy volunteers to better understand how these conditions affect rest.
BarcelonaAges 18–70 - NCT07137442Recruiting
Tic study: comparing tics and functional tics with brain tests
This study uses EEG and EMG tests to tell the difference between tics and functional tics. You may help doctors better understand and diagnose these conditions.
Bethesda, MarylandAges 18–80 - NCT07411664Enrolling by invitation
Balance and walking study for stroke, Parkinson's, or multiple sclerosis
This study uses special motion-tracking tools to measure balance and trunk control in people with first-time stroke, Parkinson’s, or multiple sclerosis. It aims to understand how these conditions affect stability, which could help tailor rehabilitation.
Kaposvár, Somogy CountyAges 18–80 - NCT07012148Recruiting
Seizure forecasting with EEG and wearables for epilepsy
This study tests a wearable device that records brain waves to help predict and track seizures in people with temporal lobe epilepsy. It may help you better understand your seizure patterns and reduce uncertainty.
Rochester, MinnesotaAges 18–75 - NCT07185555Recruiting
Low-carb diet for type 1 diabetes and obesity
This study tests a very low-energy ketogenic diet (a special low-carb, low-calorie diet) in adults with type 1 diabetes and obesity who use an automated insulin pump. It aims to see if this diet helps with weight loss and blood sugar control.
Bari, ItalyAges 18–99 - NCT07229924Recruiting
Cognitive improvement after weight-loss surgery with virtual reality
This trial tests whether a virtual reality exercise program can help improve thinking skills (like memory and attention) after bariatric (weight-loss) surgery. It may benefit people with severe obesity who are planning to have surgery.
Montreal, QuebecAges 18–65 - NCT05518617Recruiting
Imaging study for inherited Parkinson’s using PET, SPECT, and spinal fluid
This trial tests how well special brain scans (PET/SPECT) and spinal fluid tests can show changes in people with inherited (genetic) Parkinson’s. It may help researchers understand what’s happening in the brain and improve how these conditions are measured.
Exeter, DevonAges 25–80 - NCT07105475Recruiting
Deep brain stimulation for ADHD treatment
This trial uses a non-invasive technique called deep transcranial magnetic stimulation (dTMS) to treat ADHD. You will receive either high or low frequency paired stimulation to see if it helps improve symptoms.
BeershebaAges 18–65 - NCT07197138Recruiting
TMS for depression with long COVID
This trial tests whether accelerated TMS (a brain stimulation treatment) can help people with depression who also have long COVID. It may be an option if your depression hasn't improved enough with medication alone.
Munich, BavariaAges 18–65 - NCT07491380Recruiting
Blood monitoring for breast cancer drugs at home
This study tests a finger-prick blood test you can do at home to check levels of your breast cancer medication (ribociclib, abemaciclib, or palbociclib). The goal is to make monitoring easier and more convenient.
ParisAges 18 years+ - NCT05205291Recruiting
Imaging inflammation in Parkinson’s using PET/MR scans
This study uses special brain scans (PET/MR) to see inflammation in people with Parkinson’s disease or related conditions. It may help researchers better understand what drives symptoms and how inflammation changes in the brain.
ExeterAges 50–85 - NCT06805695Recruiting
Long-term follow-up for iECURE trial participants
This study follows up with people who took part in an earlier iECURE trial (such as a gene therapy study) to check on their health over time. It collects information to see how safe and lasting the treatment effects are.
LondonAges 7 months–1.3 years - NCT06868615Recruiting
MIRIA laser for skin conditions
This trial tests a laser device for various skin concerns like wrinkles, scars, acne, dark spots, or loose skin. It aims to see how well the laser works for these common issues.
Waltham, MassachusettsAges 18–70 - NCT07149428Enrolling by invitation
Deep study of smell loss causes using brain scans
This study uses brain imaging and electrical recordings to understand the brain's role in smell loss from any cause—like COVID, sinus problems, or chemotherapy. You may be eligible if you have any degree of smell loss lasting under a year.
Bethesda, MarylandAges 18–99 - NCT03973268RecruitingPhase 1
Ketamine study to understand treatment response in hard-to-treat depression
This early-stage study tests ketamine and looks at what brain changes may explain why it helps people with major depression that hasn’t improved with usual treatments. You may be asked to stay in the hospital and complete detailed interviews, mood rating scales, and brain imaging.
Bethesda, MarylandAges 18–70 - NCT04883411Recruiting
First-in-human test of new cervical spine plate and cage
This study tests a new implanted metal plate and cage to treat problems in the neck caused by worn spinal discs and nerve or spinal cord compression. It is aimed at people whose symptoms have not improved with non-surgical care for at least 6 weeks (or who have worsening nerve/spinal cord symptoms).
Union, New JerseyAges 22–79 - NCT05565833RecruitingPhase 2
Online sleep program for insomnia and thinking problems
This Phase 2 study tests an internet-based sleep program to help older adults with insomnia and related thinking difficulties. It may help improve sleep and reduce how much tiredness and sleep disruption affect daily life.
Charlottesville, VirginiaAges 65 years+ - NCT06752759RecruitingPhase 3
Ketamine mist for depression
This trial tests if a ketamine mist you breathe in can help treat moderate to severe depression. It is for adults who are not helped enough by other treatments.
Brooklyn, New YorkAges 18–88 - NCT07432867RecruitingPhase 1/Phase 2
Gene therapy for severe sickle cell disease in teens and adults
This trial tests a new gene therapy for sickle cell disease. It uses your own blood stem cells (collected from bone marrow) that are modified in a lab to help produce healthy red blood cells, then given back to you after a short chemotherapy. The goal is to reduce or stop severe complications like pain crises and lung problems.
Paris, Île-de-France RegionAges 12–35 - NCT06462196Recruiting
Study of Depression, Bipolar Disorder & Suicide Risk
This study looks at how depression, bipolar disorder, and suicide risk naturally change over time. It aims to better understand these conditions so doctors can improve treatments.
Bethesda, MarylandAges 18–120 - NCT06399107RecruitingPhase 1/Phase 2
Gene therapy trial for sickle cell disease using BAH243
This trial tests a gene therapy that uses a modified virus to deliver a healthy gene to your blood stem cells. It aims to help people with sickle cell disease produce normal red blood cells and reduce painful crises.
Beijing, Beijing MunicipalityAges 2–90 - NCT06852443Recruiting
Therapeutic chat to reduce CSAM use
This trial tests a therapeutic chat program designed to help people reduce their use of child sexual abuse material (CSAM). It is for adults who have used CSAM recently or worry about their risk.
BerlinAges 18–99
Hear when a new Drug Use Disorders trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for drug use disorders?
- Yes. Clin2 currently lists 291 recruiting drug use disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a drug use disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a drug use disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.