Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,871 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04510025Recruiting
MRI study of whole-body effects of moderate to severe COVID
This study looks at how COVID-19 affects multiple organs in the body, using MRI scans and related measurements. It may help researchers better understand who is at risk for longer-lasting or widespread effects after COVID.
OxfordAges 18–100 - NCT04512456Recruiting
Exercise training study for people with HIV and heart health
This study looks at how a structured exercise program affects the heart and blood flow in people living with HIV. It may help your care team understand who benefits most from exercise and how to do it safely.
Rio de Janeiro, Rio de JaneiroAges 30–50 - NCT04513028Recruiting
Beta-glucan with immunotherapy for melanoma immune response
This study tests whether taking beta-glucan alongside pembrolizumab changes how your immune system responds in people with stage III–IV melanoma. It may help researchers understand whether beta-glucan improves immunotherapy activity after cancer has been controlled.
Louisville, KentuckyAges 18 years+ - NCT04517383Recruiting
Sedation after clot-removal brain procedure: which helps recovery
This trial compares different types of calming medicine (sedation) after a procedure to remove a brain blood clot. It aims to see whether post-procedure sedation can improve recovery in people with a serious type of stroke.
ShanghaiAges 18–85 - NCT04520126Recruiting
Olive extract for blood vessel and heart function after heart procedures
This trial tests whether an olive extract supplement (Olivomed) improves how your blood vessels, heart, and circulation work. It focuses on people with stable or recently treated coronary heart disease and certain cholesterol patterns.
Athens, AtticaAges 18–70 - NCT04520178RecruitingPhase 2/Phase 3
5HTP trial for long-term spinal cord injury
This trial tests whether 5HTP can help people with spinal cord injury caused by trauma at least 6 months ago. It is mainly designed to see if the treatment is safe and helpful over the study period.
Louisville, KentuckyAges 18–65 - NCT04525716Recruiting
Study of how COVID-19 affected surgery patients
This study looks at how the COVID-19 pandemic changed outcomes and experiences for people who had surgery in Stockholm during the study period. It may help hospitals prepare better plans for patients during future outbreaks.
StockholmAges Any age - NCT04544969Recruiting
Testing blood markers to guide chemo for metastatic nasopharyngeal cancer
This study looks at special blood markers (CTCs) to see how sensitive your cancer is to chemotherapy and to better predict how well treatment may work. If you have metastatic nasopharyngeal cancer and can’t have local treatment, this may help match you to more effective chemo plans.
Guangzhou, GuangdongAges 18–70 - NCT04551378Recruiting
Study of how COVID affected young people with cancer
This study looks at how the COVID-19 pandemic affected the experiences of teenagers and young adults with cancer, including people who finished treatment. It may help improve support for cancer patients and survivors during public health crises.
Houston, TexasAges 18–39 - NCT04558450Recruiting
Study how COVID-19 affects blood vessel stiffness and aging
This study looks at how having COVID-19 may affect your blood vessels over the following months. It may help doctors understand long-term “vascular aging” and who is most at risk, based on how sick you were during your COVID illness.
NancyAges 18 years+ - NCT04570085RecruitingPhase 3
Caffeine treatment to improve thinking in Alzheimer’s disease
This trial tests whether changing caffeine intake can improve thinking and brain function in people with Alzheimer’s disease. You may qualify if you can follow a low-caffeine diet and have stable Alzheimer’s treatment and sleep/heart conditions.
AmiensAges 50 years+ - NCT04576078RecruitingPhase 2
Nefopam for less pain after knee replacement surgery
This Phase 2 study tests whether oral nefopam can reduce pain after total knee replacement done with spinal anesthesia. It looks at whether this medicine works better than the usual post-surgery pain plan and how safely it can be used.
Lyon, LyonAges 18–75 - NCT04575844RecruitingPhase 4
Exercise and GLP-1 to improve insulin and muscle blood flow
This study looks at whether doing exercise and a GLP-1 medicine (liraglutide or similar) can improve how your body uses insulin and how blood flows to your muscles. It is aimed at adults with metabolic syndrome who do not already have diabetes.
Charlottesville, VirginiaAges 21–60 - NCT04578249Recruiting
Blocking blue light at night after heart surgery
This trial tests whether reducing blue light at night after certain planned heart surgeries helps protect mood, thinking, and recovery. If you have no history of major mental health problems or organ problems, you may be able to join the study.
Morgantown, West VirginiaAges 45–75 - NCT04590001Recruiting
Test MobiusHD device for certain heart failure patients
This trial studies whether the MobiusHD® implant can improve symptoms or function in people with heart failure who are still limited in everyday activity. You may be eligible if your heart failure tests show moderate heart weakness and you meet specific walking and lab criteria.
Darlinghurst, SydneyAges 18 years+ - NCT04596592Recruiting
Puberty blockers and estradiol effects on heart health
This study looks at how puberty blockers and then estradiol (estrogen) may affect heart and metabolism health in teens. It may help doctors understand risks and benefits for transgender youth starting gender-affirming hormone care.
Aurora, ColoradoAges 13–16 - NCT04598399Recruiting
Mindfulness program for alcohol relapse prevention
This study compares two non-medication programs to help people with alcohol use disorder stay away from relapse. It tests whether mindfulness-based relapse prevention works better than relaxation meditation without a guide.
AngersAges 18 years+ - NCT04605146Recruiting
Telemonitoring to manage side effects from immunotherapy
This trial tests whether using home digital monitoring (telemonitoring) can help people with melanoma, lung, or kidney (renal) cancer manage side effects while on immunotherapy. It may help catch side effects earlier and support you during treatment with nivolumab plus ipilimumab or nivolumab alone.
BronAges 18 years+ - NCT04612907Recruiting
Radiation timing options for low-burden metastatic prostate cancer
This study compares different radiation schedules to the main prostate tumor in men with low-burden metastatic (spread) hormone-sensitive prostate cancer. It may help find a radiation timing approach that controls the cancer while balancing side effects.
UmeåAges 18 years+ - NCT04621279Recruiting
Cooling treatment study for babies with mild brain injury
This study compares different approaches to “cooling” treatment in newborns with mild hypoxic-ischemic encephalopathy (mild brain injury from not enough oxygen around birth). The goal is to see which approach works best and is safest for babies like yours.
Dallas, TexasAges 8 months+ - NCT04623593Recruiting
Study of cost and value of neck disc surgery
This study looks at how cost-effective (good value for the money) anterior neck disc surgery is for people with nerve or spinal cord symptoms. If you need this type of operation, it may help doctors better choose treatments and plan healthcare resources.
Maastricht, LimburgAges 18 years+ - NCT04623463Recruiting
Exercise and how it affects sleep apnea severity
This study looks at whether regular physical activity can make obstructive sleep apnea (OSA) less severe. It focuses on people who are not yet receiving OSA treatment and checks changes in severity over time.
GrenobleAges 18–80 - NCT04629352Recruiting
tDCS brain-stimulation for hearing voices in schizophrenia
This study tests whether a non-invasive brain-stimulation treatment (tDCS) can improve response to care in people who experience clinically significant hearing voices. It may help by changing brain activity, aiming to reduce or improve auditory hallucinations.
Bengaluru, KarnatakaAges 18–45 - NCT04630392Recruiting
Treadmill and vibration therapy for children with spastic cerebral palsy
This study tests whether treadmill training, with or without whole-body vibration, can improve walking and movement in children with spastic cerebral palsy. If you qualify, the goal is to see whether this exercise approach is safe and helpful.
Atlanta, GeorgiaAges 6–17
Hear when a new Effectiveness trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,871 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.