Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,871 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04425395Recruiting
Sounds without words may change pain tolerance
This study looks at whether nonverbal vocal sounds (like certain tones or sounds) change how much pain you can tolerate. You might be asked to listen to or produce sounds while your pain response is measured.
Saint-EtienneAges 18–60 - NCT04433052Recruiting
Personalized heart-protection program for people at high risk
This trial tests whether a tailored prevention plan can improve outcomes and help with costs for people at high risk of coronary heart disease. You may join if you’ve had recent heart events or scans show significant blockage, and if you can follow the visit and app requirements.
HelsinkiAges 30–80 - NCT04436965RecruitingPhase 3
Standard nutrition support for malnourished nasopharyngeal cancer patients
This Phase 3 study tests whether giving a standard nutrition plan can improve nutritional status and outcomes in people with locally advanced nasopharyngeal cancer who are malnourished. It mainly checks whether nutrition support helps you tolerate treatment and do better over time.
Guangzhou, GuangdongAges 18–65 - NCT04436081RecruitingPhase 2
CBD oil without THC for agitation in Alzheimer’s dementia
This trial studies whether a THC-free CBD oil softgel can reduce agitation in people with Alzheimer’s-related dementia. It compares CBD to a control to see if it improves difficult behaviors and is safe over the study period.
Norfolk, VirginiaAges 50–90 - NCT04441034RecruitingPhase 4
Compare two medicines for long-term pain in real life
This trial compares two types of medicines—anti-convulsants and anti-depressants—for people with persistent pain lasting more than 3 months. It aims to find out which option works better in everyday care and for which patients.
Redwood City, CaliforniaAges 18 years+ - NCT04441151Recruiting
Pulmonary rehab for adults on high-flow oxygen therapy
This trial tests whether pulmonary rehabilitation (supervised breathing and activity training) improves outcomes for adults who need high-flow oxygen. You may be eligible if your breathing and heart/vital signs are stable and your oxygen level is above a certain threshold.
Beijing, Beijing MunicipalityAges 18–100 - NCT04442971Recruiting
Music therapy for consciousness recovery after brain injury
This trial studies whether music therapy can help improve the level of consciousness in people recovering from a traumatic brain injury. If you are in early neurological rehabilitation, it may be offered as an add-on approach to support recovery.
Hessisch OldendorfAges 18–85 - NCT04443530Recruiting
Testing Ultimaster stents in everyday patient care
This trial looks at how safe and effective two specific stents are when doctors use them as part of routine care. You may be a candidate if you’re an adult receiving one of these Ultimaster stents and can follow the study check-in schedule.
ChuncheonAges 19 years+ - NCT04444349Recruiting
CoQ10 to reduce inflammation after heart surgery
This study tests whether CoQ10 (a natural nutrient) can lessen harmful inflammation and help protect organs after cardiovascular surgery. If you qualify, you may receive CoQ10 during the surgical period and be followed for how your body responds.
Beijing, Beijing MunicipalityAges 18–90 - NCT04446273Recruiting
Robotic therapy timing to improve arm movement after stroke
This trial studies whether giving robotic therapy to the shoulder and arm in a “priority” way (instead of focusing on the hand first) helps improve arm movement in people with chronic stroke. It may help by improving how your arm muscles and joints are trained to work together.
Taipei, TaipeiAges 20–75 - NCT04447911RecruitingPhase 4
Empagliflozin for chronic low blood sodium in certain fluid states
This trial studies whether empagliflozin, a blood-sugar–related medicine, can safely improve chronic low blood sodium when you are not too “dry” or have an imbalanced fluid state. It may help stabilize sodium levels and related health symptoms, but you must meet specific blood and organ-function criteria.
WürzburgAges 18 years+ - NCT04449211RecruitingEarly Phase 1
3D-printed implant for large bone defects
This trial studies whether a custom 3D-printed implant helps heal a large bone defect after injury or tumor removal. If you have a bone gap bigger than 5 centimeters and can safely have surgery, this may be a treatment option being tested.
Ho Chi Minh CityAges 18 years+ - NCT04458688Recruiting
Ocrelizumab study for relapsing MS in African Americans and Caucasians
This study looks at how ocrelizumab works in people with relapsing-remitting multiple sclerosis (MS), and it specifically includes African American and Caucasian participants. Your neurologist may already be choosing ocrelizumab as the best standard treatment for you, and the study then follows you with medical visits and MRI scans.
Detroit, MichiganAges 18–60 - NCT04469387Recruiting
Reduce adjacent back pain after lumbar surgery
This trial looks at whether a limited decompression (a careful nerve-space “freeing” procedure) can help prevent future problems in the spinal level next to your planned surgery. It targets people with spinal canal narrowing next to the surgery level but who do not yet have symptoms there.
Beijing, Beijing MunicipalityAges 18–80 - NCT04471506Recruiting
Breathing and walking program for hormonal and tumor markers
This study tests whether a combined program of interval aerobic training (alternate “hard/easy” exercise) and mindfulness breathing can improve hormone, metabolic (body chemistry/energy), and tumor marker measures in women after menopause. If you meet the criteria, you may benefit from structured activity and breathing techniques while researchers track health changes over time.
CairoAges 55–65 - NCT04473196Recruiting
See if weight-bearing changes recovery after first toe joint fusion
This study looks at whether doing more or less weight-bearing affects recovery after a first toe (1st MTP) joint fusion. It may help improve walking comfort and healing after surgery for people whose non-surgical treatments did not work.
Halifax, Nova ScotiaAges 18 years+ - NCT04472845Recruiting
Shorter or longer breast radiation after surgery for high-risk cancer
This trial compares two schedules of radiation after breast surgery in people with high-risk, node-positive breast cancer. The goal is to see whether giving radiation in 1 week or 2 weeks works well and is safe after standard treatments.
ChandigarhAges 18 years+ - NCT04477460Recruiting
Testing thicker feeds for babies after unexplained brief events
This trial looks at whether using thicker baby feeds can improve health outcomes for infants who have had their first “brief resolved unexplained event” (a short episode with no clear cause). It may help babies who are being monitored after this first episode.
Boston, MassachusettsAges birth–1 year - NCT04483076RecruitingPhase 3
Chemo before stomach surgery with different cycles
This trial studies whether giving oxaliplatin plus S-1 (SOX) chemotherapy before stomach surgery works best when given for different cycle lengths. It may help shrink stage III gastric cancer before a standard D2 gastrectomy and improve outcomes.
Beijing, Beijing MunicipalityAges 18–70 - NCT04490733Recruiting
Test dual-task walking to improve thinking in colorectal cancer
This study looks at a walking exercise that makes you do two tasks at once (for example, walking while focusing on something) to see if it can improve thinking and memory. It is for people newly diagnosed with early to mid-stage colorectal cancer, and excludes people with other cancers or cancer coming back.
TaipeiAges 40–75 - NCT04502225Recruiting
Trial of bed head elevation for high blood pressure
This study checks whether raising the head of the bed lowers blood pressure while you’re lying down in people with autonomic failure. It may help find a simple positioning change to reduce risks from high lying blood pressure.
Nashville, TennesseeAges 18–85 - NCT04504227Recruiting
Testing thickened feeds to improve safe swallowing
This study looks at how using thickened feeds may change swallowing safety and function in children who have swallowing problems (dysphagia) or who are at risk for a type of concerning breathing event. The goal is to see whether thicker liquids help protect the airway and improve swallow patterns.
Boston, MassachusettsAges Up to 21 years - NCT04505865Recruiting
Mindfulness program to reduce inflammation in heart disease
This trial studies whether a mindfulness (stress-reducing) program can lower “vascular inflammation” (inflammation in blood vessel walls) in people with stable coronary disease. It may help by improving stress and related inflammation markers while you stay on your usual heart medicines.
Boston, MassachusettsAges 45–65 - NCT04506359Recruiting
Computer-assisted clinic support after early lung cancer surgery
This trial tests a computer-assisted program that helps people with early lung cancer after tumor-removal surgery, during regular clinic visits. It may help with care planning and support tailored to you. The study is only for people who meet specific safety and language requirements.
TaipeiAges Any age
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,871 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.