Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,871 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05678452Recruiting
High-power vs low-power HOLEP for large prostates
This study compares two surgical settings (high power versus low power) during a prostate procedure called HOLEP to see which is safer and works better for people with a large prostate. If you need surgery for an enlarged prostate, this trial may help improve how the procedure is done.
CairoAges 45 years+ - NCT05678556Recruiting
Relationship education to help prevent HIV in gay and bisexual men
This trial tests a relationship education program to help reduce HIV risk by supporting safer sex choices. It is for people who are currently at higher risk and are HIV-negative.
Chicago, IllinoisAges 16–34 - NCT05681299RecruitingPhase 4
Testing growth hormone and liraglutide effects on hunger hormones
This study tests how growth hormone (GH) and liraglutide affect a hunger-related hormone system called AgRP. It compares effects in healthy people (lean or overweight) and in people with isolated GH deficiency, aiming to understand how these treatments change appetite and metabolism.
New York, New YorkAges 18–45 - NCT05686525Recruiting
TUMT vs PAE to ease severe urinary symptoms from an enlarged prostate
This trial compares two catheter-based treatments—TUMT and PAE—to see which better reduces severe urinary symptoms caused by an enlarged prostate (BPH). It may help you choose a treatment option if medicines are not suitable or you still have significant symptoms.
Copenhagen, Copenhagen NAges 40 years+ - NCT05688618Recruiting
Probiotic and fiber supplement for mild memory problems
This trial studies whether a daily supplement containing a probiotic and a fiber called inulin can improve mild cognitive impairment (mild memory/thinking difficulties) in older adults. If you have mild cognitive impairment (not dementia), you may be asked to take the supplement and be monitored over time.
Mexico CityAges 70–85 - NCT05691465RecruitingPhase 2
Radiation drug for metastatic prostate cancer with neuroendocrine cells
This Phase 2 study tests whether a radioactive medicine called lutetium Lu 177 dotatate is safe and effective for metastatic prostate cancer that has neuroendocrine features. It also checks whether patients’ scans show the cancer absorbs the drug (a requirement to start treatment).
Duarte, CaliforniaAges 18 years+ - NCT05691491RecruitingPhase 1/Phase 2
Temozolomide plus M1774 for advanced metastatic cancers
This Phase 1/2 trial tests a combination of temozolomide and M1774 to see how safe it is and whether it can help shrink advanced cancers that have spread. It focuses on certain tumor types and specific biomarker results, and it may be an option if standard treatments have been tried or aren’t possible.
Irvine, CaliforniaAges 18 years+ - NCT05696561Recruiting
Testing a glaucoma procedure called canaloplasty device
This trial studies whether a canaloplasty device is safe and effective for people with open-angle glaucoma who are planning cataract surgery. It may help lower eye pressure when using eye drops is being reduced or stopped.
SantiagoAges 22 years+ - NCT05697406RecruitingPhase 1/Phase 2
Uses MRI to study tumors in people with cancer
This early study tests how well MRI (a type of scan) can help measure a substance related to tumors. If you already have cancer and are able to have an MRI scan, you may be able to take part.
Baltimore, MarylandAges 18–88 - NCT05698576Recruiting
Laser treatment through the skin for men with prostate cancer
This trial tests a laser procedure done through the skin between the scrotum and anus, guided by MRI and ultrasound, for men with certain prostate cancer types. It aims to heat and treat prostate cancer while checking safety and outcomes over follow-up visits.
Hialeah, FloridaAges 50–80 - NCT05699174RecruitingPhase 3
Compare two antibiotic routes for infected broken bones after surgery
This Phase 3 trial tests whether giving antibiotics by mouth (PO) works as well as giving antibiotics through a vein (IV) for an infected fracture that has not healed after prior surgery. It may help you understand which approach is safer and more effective for getting the bone to heal.
Indianapolis, IndianaAges 18 years+ - NCT05701865Recruiting
Study of alcohol effects on people who help others
This study looks at how a one-time intoxication (drinking a measured amount of alcohol) may affect a person’s willingness and ability to intervene and help in a bystander situation. It’s mainly about understanding behavior and decision-making, not treatment for alcohol use problems.
Atlanta, GeorgiaAges 21–30 - NCT05701254Recruiting
Study how type 1 diabetes affects fracture risk bones
This study compares bone structure in women with type 1 diabetes versus women without diabetes, to understand why fractures can happen more easily. You may need blood tests, scans, and a small bone biopsy (a surgical sample from your hip/thigh area).
Omaha, NebraskaAges 50 years+ - NCT05701982Recruiting
Walking plus Tai Chi coach via video for COPD and pain
This study tests whether a phone/computer program that combines walking training with Tai Chi improves physical function (how well you move) in people who have COPD and long-term body or muscle pain. It may help you build strength, balance, and safer movement—especially if pain makes activity hard.
Boston, MassachusettsAges 40–100 - NCT05701969RecruitingEarly Phase 1
Melatonin for sleep during night shifts in residents
This early study tests whether melatonin can improve sleep patterns for doctors-in-training during overnight “night float” shifts. It may help you feel more rested and adjust to night work.
Charlottesville, VirginiaAges 18 years+ - NCT05706155Recruiting
Switching some animal protein to plant protein for Type 2 diabetes
This study tests whether replacing part of your animal protein with plant-based protein can improve Type 2 diabetes control. It may help your blood sugar and weight management without changing everything about your diet.
Porto Alegre, Rio Grande do SulAges 18–65 - NCT05706831Recruiting
Music and gentle brain stimulation after neurological injury
This trial tests whether combining music with gentle electrical brain stimulation can improve symptoms after a neurologic event, such as language and attention problems. It’s meant for adults who are living with effects of stroke and certain levels of reduced awareness.
Bari, BaAges 18 years+ - NCT05707871RecruitingEarly Phase 1
Testing how low-nicotine cigarettes affect heart measurements
This early study checks whether very low-nicotine cigarettes change heart-related measurements during a lab visit. It may help researchers understand how lowering nicotine could affect cardiovascular (heart and blood vessel) function.
Winston-Salem, North CarolinaAges 21 years+ - NCT05708443Recruiting
Exercise training to improve walking and daily activities in COPD
This trial studies whether doing a combination of endurance exercises can help people with COPD walk better and do everyday activities with less limitation. It compares an exercise approach aimed at improving walking function and daily movement.
Lumezzane, BresciaAges Any age - NCT05708859RecruitingPhase 4
Tirzepatide to slow plaque buildup in coronary arteries
This trial studies tirzepatide to see if it can slow the progression of coronary artery plaque in people with type 2 diabetes. It uses special heart CT scans to track changes over time.
Torrance, CaliforniaAges 40–80 - NCT05711849RecruitingPhase 2
Stem cell treatment for long-lasting chest pain not helped by meds
This Phase 2 trial tests whether stem cells placed into the heart artery can safely reduce symptoms in people with “refractory” angina (chest pain) despite maximum heart-healthy medication. You may qualify if your chest pain is limiting your activity and other heart procedures (stents/bypass) aren’t possible or are too risky.
London, EnglandAges 18 years+ - NCT05712395Recruiting
Pain-free exercise program for people with leg artery disease
This trial tests a new kind of exercise that is meant to be non-ischemic (not reduce blood flow) and pain-free, to see if it helps people with peripheral artery disease (PAD) who get leg pain when walking. You may be eligible if you have PAD confirmed by specific treadmill and blood-pressure measurements and meet the exercise and health safety requirements.
Oklahoma City, OklahomaAges 40 years+ - NCT05718622Recruiting
EECP for people with stable first stroke and blocked artery
This study looks at whether EECP (a non-surgical therapy that helps blood flow) improves outcomes in people who recently had their first ischemic stroke and have a narrowed or blocked artery. It also aims to predict who may benefit most based on health data.
Xi'an, ShaanxiAges 18–80 - NCT05721599Recruiting
Nutrition and lifestyle counseling for older adults with diabetes
This trial tests whether a combined nutrition and lifestyle counseling program can improve health and daily functioning in frail older adults with type 2 diabetes. It may help by giving structured guidance to support safer, healthier routines.
Hualien CityAges 65 years+
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,871 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.