Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,866 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05838950Recruiting
Short high-intensity exercise program for cardiometabolic health
This trial studies whether a structured, short high-intensity exercise program can improve health markers related to weight, blood sugar, and blood fats in young adults with obesity. It may help you see if this kind of exercise leads to measurable health improvements.
Syracuse, New YorkAges 18–25 - NCT05839314RecruitingPhase 4
Huaier granules for idiopathic membranous nephropathy with PLA2R
This trial studies whether Huaier granules can improve kidney disease activity in people with “idiopathic membranous nephropathy” who test positive for PLA2R antibodies and are still not in remission. Participants will also have been on standard blood-pressure/kidney-protecting treatment (called RASI) for at least 4 weeks.
Beijing, Beijing MunicipalityAges 18–75 - NCT05839535RecruitingPhase 2
Baduanjin plus brain stimulation for knee osteoarthritis pain
This Phase 2 study tests whether combining Baduanjin (a guided mind-body movement) with neuromodulation can improve knee osteoarthritis symptoms and function. It compares education-based stretching/control and uses MRI scanning as part of the research.
Charlestown, MassachusettsAges 45–75 - NCT05840497Recruiting
Exercise program to help lower gestational diabetes risk
This trial tests whether a strength and resistance exercise program during pregnancy can help reduce gestational diabetes in people who are overweight or obese. It may help by improving how your body handles sugar during pregnancy.
Pamplona, NavarreAges 18 years+ - NCT05840302Recruiting
Pain education program to increase activity in chronic low back pain
This trial studies whether teaching “pain neuroscience” (how pain works in the body and brain) helps people with long-term low back pain move more. It compares an education program as part of a multidisciplinary rehab to usual care during your planned hospital stay.
Lamalou-les-BainsAges 18 years+ - NCT05842382RecruitingPhase 2
High-dose IV vitamin C for severe pneumonia
This trial tests whether high-dose vitamin C given through an IV can improve outcomes in people with severe pneumonia. It may help your body fight infection and reduce complications, but it also has several safety checks.
Alor Star, KedahAges 18 years+ - NCT05844644RecruitingPhase 2
Golo plan for weight and blood sugar in prediabetes
This trial tests whether the Golo for Life plan (with a release supplement) can improve blood sugar and help with weight in adults who have prediabetes or type 2 diabetes. If you join, you’ll follow the program and attend clinic visits while your health, diet, and weight are tracked.
LaSalle, OntarioAges 18–75 - NCT05845905Recruiting
Remote arm treatment to lower blood pressure in older adults
This study tests whether a simple “remote conditioning” method done on the arm can help lower blood pressure in older adults with hypertension. It may help people whose blood pressure is high but not dangerously high at the time of screening.
Changchun, JilinAges 65–85 - NCT05846438Recruiting
Drain care check after breast implant surgery
This study looks at whether a specific way of caring for surgical drains can lower infection rates and improve quality of life after breast reconstruction with a tissue expander. You may be asked to follow the study’s drain-care steps during recovery.
Columbia, MissouriAges 18–100 - NCT05847478Recruiting
Acupressure vs eating plan breaks for specific stomach syndrome
This study compares ear (auricular) acupressure to an intermittent dietary restriction approach in children who have a particular “stomach heat and dampness” pattern from Traditional Chinese Medicine. The goal is to see which method better helps children with certain weight and blood-sugar or cholesterol risks.
ShanghaiAges 6–18 - NCT05895019Recruiting
Propofol’s effects on brain function in Parkinson’s surgery
This study tests how propofol, a common anesthesia medicine, affects brain activity in people with Parkinson’s disease during planned surgery. It also compares them with people without Parkinson’s during similar non-brain, non-heart surgery.
Beijing, Beijing MunicipalityAges 18–80 - NCT05851859Recruiting
Breathing training for long COVID symptoms
This study tests whether a structured breathing control technique can improve symptoms of long COVID. It may help by training how you breathe, but you must meet specific health and medication criteria to join.
Saint-DenisAges 18 years+ - NCT05853094Recruiting
Testing different ways to create a stoma after rectal cancer surgery
This trial looks at how different stoma (opening in the belly) approaches affect recovery after curative rectal cancer surgery. It may help doctors choose the safest, most comfortable option for bowel function and healing after surgery.
ShanghaiAges 18–80 - NCT05853627RecruitingPhase 4
Propranolol versus standard therapy for trauma imagery reactions
This study tests whether propranolol (a beta-blocker) changed alongside a standard approach can reduce how strongly your body reacts during traumatic imagery. It’s meant for adults who have had a traumatic event and may help lessen fear and stress responses tied to those memories.
Charlestown, MassachusettsAges 18–65 - NCT05854706Recruiting
Theta-burst brain stimulation for major depression
This study tests whether a type of brain stimulation (theta-burst stimulation) changes a blood marker called BDNF in people with major depressive disorder. It may help researchers understand whether this treatment can improve depression biology.
Taipei, Taipei CITYAges 20–65 - NCT05857371RecruitingPhase 2
Stem cell–like treatment injection after urethrotomy for urethral narrowing
This Phase 2 trial tests whether injecting a patient’s own fat-derived cells during an endoscopic procedure can safely improve healing in bulbar urethral narrowing. It’s mainly for men with a specific type and short length of narrowing who can temporarily stop certain immune-suppressing medicines.
MarseilleAges 18–85 - NCT05857800Recruiting
Studying how lung tumor treatment affects the tumor environment
This trial studies how “before-surgery” (neoadjuvant) lung cancer treatments change the tumor environment by monitoring patients during care. It may help doctors better choose therapies and predict who benefits from treatment.
ShanghaiAges 18 years+ - NCT05857891Recruiting
Erythropoietin to help clear lung fluid in ARDS
This trial tests whether erythropoietin (EPO), a medicine that affects red blood cell production, can help clear extra fluid from the lungs in people with acute respiratory distress syndrome (ARDS). If it works, it could improve breathing and reduce lung fluid buildup during critical illness.
Wenzhou, ZhejiangAges 18 years+ - NCT05858255Recruiting
Exergaming program for people with psychosis
This study tests whether an “exergaming” exercise program (video games that make you move) can help people with schizophrenia-spectrum conditions. It’s meant to see if this kind of guided activity is safe and beneficial for symptoms and wellbeing.
Tønsberg, VestfoldAges 18–65 - NCT05858411Recruiting
Biologic gum treatments added to non-surgical cleaning
This trial studies whether adding a biologic medicine to standard non-surgical gum (periodontal) treatment can improve deep gum pockets in certain bone defects. It may help people whose gum disease has specific “intrabony” defects, but you must meet several health and medication rules.
TiranaAges 18 years+ - NCT05859022Recruiting
Bariatric treatment methods compared for diabetes and metabolism
This trial compares a less invasive heart/artery-based bariatric treatment (bariatric arterial embolization) with standard weight-loss surgery to see how they affect metabolism and type 2 diabetes. You might be considered if you have obesity with type 2 diabetes and have not had prior bariatric surgery.
LisbonAges 18–75 - NCT05859451Recruiting
Heated tobacco product study for surgically treated leg fractures
This study looks at whether a tobacco heating system (instead of cigarettes) affects how well a surgically repaired tibia or femur fracture heals. It mainly targets smokers with a certain smoking history who do not want to join free smoking-cessation seminars.
Tübingen, Baden-WurttembergAges 18 years+ - NCT05861505RecruitingPhase 3
Treatment for new liver spread from colon cancer recurrence
This Phase 3 trial studies a treatment approach for people whose colorectal cancer has come back in the liver within 12 months and can be treated with local procedures. It aims to see whether the study treatment can improve outcomes compared with standard care for people with a limited number of liver tumors.
AmsterdamAges 18 years+ - NCT05861999RecruitingPhase 4
Risdiplam for young children with SMA after gene therapy plateau
This trial studies whether risdiplam is safe and helpful for children under 2 with spinal muscular atrophy (SMA) whose function has leveled off or declined after gene therapy. It may be an option if you saw benefits from gene therapy but then noticed a stop or setback in key abilities.
Little Rock, ArkansasAges 3 months–2 years
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,866 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.