Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,873 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01477957Recruiting
Bariatric surgery and changes in insulin and body energy use
This study tests whether weight-loss surgery improves how your body uses insulin and energy. It compares insulin sensitivity and related measurements before and after surgery to understand who benefits.
Düsseldorf, North Rhine-WestphaliaAges 20–70 - NCT00981396RecruitingEarly Phase 1
EFT therapy to help smokers who struggle to quit
This early-stage study tests Emotional Freedom Techniques (EFT), a gentle talking-and-tapping method, for people who feel very anxious about quitting and still have strong cravings. It may help improve confidence and reduce the emotional triggers that make quitting harder.
Ormskirk, LancashireAges 12–99 - NCT01143480Recruiting
Testing how the body responds to endotoxin
This study checks how your immune system (your body’s defense system) reacts to a controlled substance that triggers inflammation. It may help researchers understand why some people have stronger or weaker inflammatory responses.
Research Triangle Park, North CarolinaAges 18–100 - NCT01631617RecruitingPhase 2
Atopic dermatitis treatments and how they affect skin
This Phase 2 study tests different treatments for atopic dermatitis (eczema) by looking at changes in skin health. It may help people find safer, more effective ways to control moderate to severe eczema and related skin infections.
Bethesda, MarylandAges 2–50 - NCT01653223Recruiting
Simvastatin to protect the heart during heart surgery
This trial looks at whether simvastatin (a cholesterol medicine) can help protect the heart during cardiac surgery. You might be invited if you’re having surgery for certain, non-complex heart conditions, but not if you have some specific related health problems.
Guangzhou, GuangdongAges 18 years+ - NCT01719055Recruiting
Long-term follow-up for Boston Scientific pain nerve stimulation
This study looks at how well a Boston Scientific nerve stimulation device works over the long term for pain in everyday care. You may be able to join if you’re already being set up to use one of these approved systems and can reliably report your pain outcomes.
Phoenix, ArizonaAges 18 years+ - NCT02410850Recruiting
Test how well long-term mouth devices work for sleep apnea
This trial looks at how effective an oral (mouth) appliance is over the long term for people with obstructive sleep apnea. If you already use a mouth device, this study may help doctors understand whether it continues to work well over time.
Vancouver, British ColumbiaAges 18–90 - NCT02823665RecruitingEarly Phase 1
Compare how bariatric surgery affects blood sugar changes
This early trial studies how blood sugar moves in people after certain weight-loss surgery compared with people without surgery. It may help researchers understand why blood sugar can drop too low and how treatments like atropine affect that process.
San Antonio, TexasAges 18–65 - NCT02216500Recruiting
Study ketogenic diet effects in people with epilepsy
This study looks at how a high-fat, low-carbohydrate ketogenic diet may change electrical activity in the brain and related body measurements in people with epilepsy. You may be asked to follow the diet and keep records so the researchers can compare changes over time.
Gainesville, FloridaAges Up to 50 years - NCT02784210RecruitingPhase 2
Steroid treatment to reduce inflammation in active MS lesions
This Phase 2 study tests whether corticosteroid medicine can reduce inflammation at the edge of active multiple sclerosis (MS) plaques seen on MRI. It may help calm “hot” areas in the brain where MS activity is happening.
Bethesda, MarylandAges 18–120 - NCT02299921Recruiting
Alcohol and drug effects on immunity in ICU breathing patients
This study looks at how alcohol and other drugs can affect the body’s immune system in people who are very sick in the ICU due to breathing problems. It may help doctors better understand immune changes during critical illness and respiratory failure.
Aurora, ColoradoAges 18–90 - NCT02890485Recruiting
Dry needling for knee pain with stair or squat pain
This study tests whether dry needling can reduce ongoing knee pain in people who feel pain around the kneecap when going up or down stairs, squatting, or running. You may be able to join if your knee pain has lasted at least 3 months and you’re referred to physical therapy.
Columbus, OhioAges 18–40 - NCT02691858Recruiting
Hydrocortisone for babies with bowel telescoping after air treatment
This trial looks at whether giving hydrocortisone (a steroid medicine) can improve outcomes for infants with intussusception, a condition where part of the bowel slips into another part. It specifically focuses on babies treated with a non-surgical air method to push the bowel back in place.
CairoAges 3 months–4 years - NCT02323399RecruitingPhase 4
IV medicine study for blood pressure effects during anesthesia
This trial studies how phenylephrine given through an IV affects blood pressure during procedures under general or spinal/epidural anesthesia. It may help doctors understand how to control blood pressure more safely during surgery.
Wilmington, DelawareAges 12–16 - NCT02781519RecruitingPhase 1
Study how THC affects men and women who have used cannabis before
This Phase 1 study tests how delta-9 THC (the main active ingredient in cannabis) affects healthy adults, and whether the effects differ by gender. It may help researchers understand risks and responses to THC, which could guide safer use and future treatments.
West Haven, ConnecticutAges 18–55 - NCT02883647Recruiting
Stopping antiviral treatment in chronic hepatitis B
This trial studies what happens after stopping long-term hepatitis B antiviral medicine in people whose virus has stayed controlled. It also follows patients over time to see how well they remain stable and safe after stopping.
Guangzhou, GuangdongAges 18–65 - NCT02573753Recruiting
Study how sleep affects gut bacteria and health
This study looks at how different sleep patterns change the microorganisms in your gut (gut bacteria) and what that may mean for health. It’s mainly for people who can take part in other approved research studies at the same time.
Rochester, MinnesotaAges 18 years+ - NCT02880891Recruiting
Splinting vs not splinting dental crowns on implants
This trial compares two ways of connecting single dental crowns (splinted vs not splinted) on dental implants. It looks at how well the gums and bone stay stable around the implants over time, after the crowns are put in.
Beijing, Beijing MunicipalityAges 20 years+ - NCT02195050Recruiting
Study links between abnormal blood fats and health risks
This study looks at why triglycerides and cholesterol can be abnormal and how that may affect organs like nerves, liver, and metabolism. You may be included if you already take a statin, have certain triglyceride levels, diabetes, kidney disease, or specific lab patterns suggesting inherited fat disorders.
ManchesterAges 18 years+ - NCT02811510RecruitingPhase 1
Study of THC effects on people with past cannabis use
This Phase 1 study tests how THC (the main active ingredient in cannabis) affects healthy adults, and whether effects differ by gender. It’s designed to learn about short-term body and brain responses to THC.
West Haven, ConnecticutAges 18–55 - NCT02646475RecruitingPhase 1
Study angiotensin medicine to improve metabolism in obesity
This Phase 1 study tests how a medication that affects the body’s angiotensin system (angiotensin-(1-7)) changes metabolism in adults with obesity, insulin resistance, and high blood pressure. It may help researchers understand whether this approach can improve blood sugar/insulin function and related body changes.
Nashville, TennesseeAges 18–60 - NCT02844738RecruitingPhase 2
Cell therapy for shoulder osteoarthritis pain and inflammation
This trial tests a treatment using your own (autologous) regenerative cells to reduce pain and inflammation from shoulder osteoarthritis. It may help people with long-lasting shoulder pain, but you must meet several health and medication timing requirements.
Grove City, PennsylvaniaAges 18–90 - NCT02844764RecruitingPhase 2
Cell therapy test for hip osteoarthritis pain and swelling
This trial tests an “autologous” regenerative cell treatment, meaning cells taken from you, to reduce hip osteoarthritis pain and inflammation. It checks safety first and looks for improvements in how you feel and move.
Grove City, PennsylvaniaAges 18–90 - NCT02844751RecruitingPhase 2
Regenerative knee cell therapy for arthritis pain and swelling
This Phase 2 study tests a patient’s own (autologous) regenerative cell treatment to reduce knee pain and inflammation from osteoarthritis. It mainly looks at whether the treatment is safe and whether it can improve symptoms over time.
Grove City, PennsylvaniaAges 18–90
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,873 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.