Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,873 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02257723Recruiting
Testing combined Korean herbal and therapy for hospitalized spine or joint pain
This trial studies whether a combined complementary treatment approach helps people who are hospitalized for spine or joint problems. It may help reduce the types of pain that come from those areas.
Seoul, Gangnam-GuAges Any age - NCT02455193Recruiting
Exercise study for people with schizophrenia
This study looks at how exercise affects brain function in people with schizophrenia or schizoaffective disorder. It may help researchers understand whether exercise can improve brain-related outcomes alongside standard treatment.
Aurora, ColoradoAges 21–70 - NCT02323945Recruiting
Low-oxygen breathing to improve leg movement after spinal injury
This study tests whether breathing brief, mild low-oxygen air (under supervision) can improve leg mobility in people with a certain type of spinal cord injury. It may help with regaining movement, especially if you can already move your legs voluntarily but still have mobility limits.
Cambridge, MassachusettsAges 18–75 - NCT02630121RecruitingPhase 4
Nasal spray treatment to reduce mild sleep apnea congestion
This study tests whether using oxymetazoline with fluticasone nasal spray can improve mild obstructive sleep apnea by lowering nasal congestion. If your nose stays blocked most days despite current spray use, this may help your breathing during sleep.
Tampa, FloridaAges 18–65 - NCT02897063RecruitingPhase 1
Test medicines for low blood pressure in nerve-related disorders
This early (Phase 1) study tests whether midodrine and droxidopa can improve blood-flow pooling in the belly in people with nerve problems that affect blood pressure when standing. It’s looking at safety and how the body responds, which may help reduce dizziness or fainting for some participants.
Nashville, TennesseeAges 40–80 - NCT02391519Recruiting
Study how high altitude affects body energy signaling
This study compares how the body responds to high altitude around the time of a planned C-section, including a signal involved in energy use. It may help researchers understand why pregnancy and blood-vessel function can differ at higher elevations.
Aurora, ColoradoAges 18–45 - NCT02918188RecruitingPhase 2
Hydrogen therapy for steroid-resistant graft-versus-host disease
This Phase 2 study tests whether hydrogen therapy can improve symptoms in people with chronic graft-versus-host disease (cGVHD) who cannot tolerate steroid treatment. If steroids aren’t working or can’t be used, this trial may offer an alternative approach to help control the illness.
Beijing, Beijing MunicipalityAges Up to 65 years - NCT02954939Recruiting
Test medicines to change immune cells in lupus kidney flare
This study tests whether mycophenolate mofetil and cyclophosphamide can improve active lupus kidney inflammation by changing immune cell patterns in your blood. It may help patients whose lupus nephritis is currently active, shown by worsening urine protein and/or kidney blood tests.
Hong KongAges 18–80 - NCT03155854Recruiting
Surgery to prevent scarring in trigger finger
This study looks at whether doing a limited surgery in advance can improve outcomes and reduce scarring for people with trigger finger who also have a specific palm cord condition. It may help you heal better if you’ve already tried non-surgical treatment or chose surgery.
Rochester, MinnesotaAges 18 years+ - NCT02977468RecruitingPhase 1
Pembrolizumab for early triple-negative breast cancer tumor changes
This Phase 1 study tests pembrolizumab (an immune medicine) to see how it affects the tumor and its surroundings in triple-negative breast cancer. It’s mainly looking at safety and early signs of benefit, especially in a limited, early-stage breast tumor.
Atlanta, GeorgiaAges 21–80 - NCT02920554Recruiting
Surgery comparison for T2–T3 gallbladder cancer
This study looks at whether a specific type of liver surgery (removing tissue in a wedge shape versus a different liver resection) improves outcomes for some patients with T2 or T3 gallbladder cancer. It may help decide the best surgical approach after the gallbladder has already been removed.
SuwonAges 19–80 - NCT03275194RecruitingPhase 2
HIPEC during interval surgery for advanced ovarian cancer
This trial looks at whether a heated chemotherapy treatment given in the abdomen during a planned second surgery (HIPEC) can improve outcomes for certain advanced ovarian cancers. It is for people who have already had initial chemotherapy and partially responded, with enough health to safely undergo surgery.
Mexico CityAges 18–70 - NCT03375866Recruiting
Mixed nuts trial to help you feel full and manage weight
This trial tests whether eating a mix of nuts helps people feel full longer (satiety) and manage weight. It may be most helpful if you are trying to improve weight control and can safely eat nuts.
San Diego, CaliforniaAges 18–55 - NCT02923011RecruitingPhase 3
MR-guided ultrasound vs radiofrequency heat for osteoid osteoma pain
This trial compares two non-surgical treatments that heat a small bone tumor to stop pain: MR-guided focused ultrasound and radiofrequency heat. It aims to find which option works better and has fewer problems for people whose osteoid osteoma pain is not well controlled.
Palo Alto, CaliforniaAges 8 years+ - NCT03320304Recruiting
VNS for long-term depression that hasn’t improved with treatment
This trial studies how well and how efficiently VNS therapy works for people with long-lasting or repeated major depression that hasn’t responded to enough antidepressant treatments. It may help patients who are already receiving depression treatment but are still struggling.
ViennaAges 18 years+ - NCT02947503RecruitingPhase 3
Metformin for gestational diabetes in pregnancy outcomes
This study tests whether taking metformin during pregnancy improves outcomes for people with gestational diabetes. It may help with pregnancy health and baby outcomes compared with the study’s other diabetes care plan.
GroningenAges 18–45 - NCT03303586Recruiting
Compression stockings to improve nighttime asthma symptoms
This study tests whether wearing compression stockings at night can reduce asthma symptoms during sleep. It may help some people notice fewer nighttime breathing problems.
Toronto, OntarioAges 20–75 - NCT03380221Recruiting
Watermelon eating study for fullness and heart health markers
This study tests whether eating fresh watermelon changes how full you feel and affects markers related to heart and metabolic health. It’s aimed at adults who fit certain age and body-size ranges and can follow the study’s food rules.
San Diego, CaliforniaAges 18–55 - NCT03240328RecruitingPhase 1
CAR-T therapy study for rebuilding HIV immune defenses
This early-stage study tests whether CAR-T cells can help rebuild the immune system’s ability to fight HIV. You may be a candidate if your HIV is well controlled on standard treatment and you don’t have certain serious infections or organ problems.
Guangzhou, GuangdongAges 18–60 - NCT03161652RecruitingPhase 2
Levosulpiride for diabetic eye swelling and retinopathy
This Phase 2 study tests whether levosulpiride can improve changes in the retina in people with diabetic retinopathy and diabetic macular edema (eye swelling that can affect vision). It may help by targeting chemicals in the body that could affect eye tissue and inflammation.
Querétaro City, QuerétaroAges 40–69 - NCT03295981RecruitingPhase 3
Bisphosphonate treatment to prevent giant cell tumor return
This study looks at whether taking a bone-strengthening medicine called a bisphosphonate after surgery can lower the chance that a giant cell tumor in a leg or arm comes back. It may help prevent recurrence after removing the tumor from the bone.
Los Angeles, CaliforniaAges 18 years+ - NCT03321045RecruitingEarly Phase 1
PET scan to predict benefit from HER2-targeted breast cancer therapy
This early-phase study uses a special PET scan with a drug tagged for imaging to predict how well HER2-targeted treatments will work. It may help doctors choose the most effective therapy for HER2-positive breast cancer.
Birmingham, AlabamaAges 18 years+ - NCT07676773Recruiting
Remote exercise study for type 2 diabetes
This trial tests if a remote exercise program can help control blood sugar and improve fitness in people with type 2 diabetes. It is for those who are newly diagnosed or have had diabetes for up to 5 years and are not taking diabetes medication.
Chengdu, SichuanAges 18–69 - NCT07675200Recruiting
Miricell study on healthy aging and cell cleanup
This study tests whether a supplement called Miricell can improve markers of healthy aging and help your cells clean out damaged parts. If you are healthy, between 40 and 70 years old, and willing to follow a specific diet and visit schedule, you may be able to join.
Canfield, OhioAges 40–70
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,873 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.