Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,374 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05988385Recruiting
Treating sleep apnea to protect memory in older adults
This study tests whether treating sleep apnea can help protect memory and brain health in older adults. It involves using a CPAP machine or other treatments for sleep apnea and may include memory tests and brain scans over 2 years.
Tucson, ArizonaAges 55–85 - NCT05979168Recruiting
Text message program to help control high blood pressure in Nepal
This study tests whether receiving text messages on your phone can help Nepali adults with high blood pressure better control their condition. The program supports medication use and healthy habits through simple mobile messages.
Kathmandu, BagmatiAges 18–70 - NCT05975593Recruiting
Study how radiation affects tumor biology in cervical or pancreatic cancer
This study looks at how radiotherapy changes the tumor environment, using lab samples collected during treatment. It may help researchers understand why radiation works differently for different people and could improve future treatment planning.
St Louis, MissouriAges 18 years+ - NCT05987410Recruiting
Nordic walking for weight and heart health after a cardiac event
This trial tests if a nordic walking program helps people with diabetes who are overweight or obese recover after a heart attack or heart procedure. If you had a heart event or stent/bypass in the last 3 months, this program could help you get stronger and manage your weight.
MilanAges 18 years+ - NCT05997979RecruitingPhase 3
Capsaicin patch for nerve pain in children after surgery or injury
This trial tests whether a capsaicin 8% skin patch can safely reduce nerve pain in children ages 12 to 17 who have had pain for more than 3 months after surgery or an injury. The patch is applied to the painful area and may offer relief without daily pills.
AmiensAges 12–17 - NCT05982795Recruiting
How CF modulators affect lung bacteria
This study looks at how highly effective CF modulator therapies change the bacteria living in the lungs of people with cystic fibrosis. Understanding these changes may help improve future treatments.
Lebanon, New HampshireAges 18–99 - NCT05973461Recruiting
Exercise and virtual reality study for depression
This study looks at whether doing regular exercise and using virtual reality can help with depression symptoms, compared to not doing them. You may be included even if you do not currently have depression symptoms, as long as you meet the safety and participation requirements.
Arlington, TexasAges 18–65 - NCT05954130Enrolling by invitation
Sexual health education for early pregnancy
This study tests whether a web-based course about sexual health during pregnancy can improve your sexual wellbeing. It focuses on people who are in their first trimester and have not already received similar sexual health education.
AdanaAges 18–35 - NCT05955066RecruitingPhase 4
Testing a JAK inhibitor to help RA joint erosion heal
This Phase 4 study tests whether a JAK inhibitor (baricitinib) can improve how RA-related bone erosion heals. You might be eligible if you have rheumatoid arthritis that is still active despite methotrexate treatment, and you meet the specific safety and medication history rules.
Hong Kong, Hong KongAges 18–65 - NCT05945043Recruiting
Study breathing signals during fluid drain in pleural effusion
This trial looks at how a breathing control system (called neural respiratory drive) changes when doctors remove lung lining fluid using a thoracocentesis, chest drain, or an indwelling pleural catheter. It may help improve how safe breathing measurements are taken during these common procedures.
London, LondonAges 18 years+ - NCT05953948Enrolling by invitation
Smartphone case management program for liver transplant patients
This trial studies whether an “intelligent” phone-based case management program can help people after a liver transplant. You may be able to participate if you’re a liver transplant recipient and can use a smartphone, but not if you have liver-related confusion.
Taoyuan, TYAges 20 years+ - NCT05959551Recruiting
Brain stimulation study to change brain connections
This study tests whether a non-surgical brain stimulation technique (placing a gentle electrical current through the scalp) can change how different parts of the brain communicate. It may help researchers understand treatments for brain function—if you’re eligible and don’t have certain safety concerns.
Winnipeg, ManitobaAges 18 years+ - NCT05957523Recruiting
Remote ischemic preconditioning and blood markers in healthy adults
This study tests whether a simple, non-invasive procedure on your arm can change certain substances in your blood. It may help researchers understand how to protect the body from injury.
Xi'an, ShaanxiAges 18–45 - NCT05972356Recruiting
How heart relaxation affects outcomes in heart surgery
This study looks at whether a measurement of how well the heart relaxes helps predict outcomes after heart surgery. It focuses on patients treated in Amsterdam UMC and uses care data to understand who may be at higher or lower risk.
Amsterdam, North HollandAges 18 years+ - NCT05945199Recruiting
Brain stimulation to reduce cravings in chemsex users
This trial tests a non-painful brain stimulation method (tDCS) to help reduce cravings related to chemsex. If you qualify, you’ll be randomly assigned to real stimulation or a sham (placebo) and complete study visits and questionnaires.
DijonAges 18 years+ - NCT05964387Recruiting
Silver fluoride treatment and local numbing for tooth cavities
This study tests whether applying silver diamine fluoride (a cavity-stopping liquid) changes how well local numbing works during dental treatment for certain tooth defects. It may help determine the safest and most comfortable way to treat weak, cavity-prone molars in children.
Ann Arbor, MichiganAges 6–11 - NCT05945212Recruiting
Vibration therapy to help leg recovery after subacute stroke
This study tests whether a program using local vibrations on the muscles in the front of your ankle can improve leg nerve and movement recovery after stroke. It may help people who have weak ankle lifting during the weeks to months after stroke.
Le Chambon-FeugerollesAges 18–80 - NCT05957913Enrolling by invitationPhase 2
Testing antiviral drugs to control Epstein-Barr virus in MS
This Phase 2 study tests whether certain antiviral medicines can reduce Epstein-Barr virus (EBV) activity. If you have multiple sclerosis and evidence of EBV infection, the results may help clarify new ways to target EBV-related disease activity.
Boston, MassachusettsAges 18 years+ - NCT05969457RecruitingPhase 3
Local pain-numbing injection before surgery for hysterectomy
This Phase 3 study tests whether a preventive numbing medicine injection before a vaginal hysterectomy (using the vNOTES approach) can reduce pain afterward. It may help with comfort and recovery after surgery for non-cancer reasons.
Le HavreAges 18–70 - NCT05967819Recruiting
Study stress and exercise effects on missing periods
This study looks at how physical and stress load from exercise may affect hormone signals that help bring on regular menstrual periods in exercising women. You might benefit by learning more about your hormone and cycle patterns while being monitored through exercise, stress, and at-home measurements.
Colorado Springs, ColoradoAges 18–35 - NCT05961501Enrolling by invitationPhase 2/Phase 3
CBD and CBN for long-lasting facial pain and muscle headaches
This trial tests whether CBD and CBN can reduce facial pain and headaches caused by muscle-related problems that have lasted more than 3 months. It may help people who have ongoing symptoms find a new treatment option.
WroclawAges 18 years+ - NCT05972564RecruitingPhase 1/Phase 2
SGLT2 inhibitor for metabolic syndrome and heart health
This study tests whether a diabetes medication called an SGLT2 inhibitor can reduce inflammation in body fat and improve blood vessel function in people with metabolic syndrome. It may help prevent heart disease and other complications.
Nashville, TennesseeAges 18 years+ - NCT05955846Recruiting
Testing a new cataract lens with a virtual aperture
This trial tests a specific cataract replacement lens to see how safe it is and how well it improves vision. If you have cataracts in both eyes and are good candidate for cataract surgery, this lens may help you see more clearly after surgery.
CoimbraAges 40–75 - NCT05377216RecruitingEarly Phase 1
Testing nerve stimulation effects during heart ablation
This trial studies how a type of nerve stimulation affects the heart’s electrical signals during a procedure to treat a dangerous fast heart rhythm (ventricular tachycardia). It may help doctors better understand safety and effects during planned ablation.
Philadelphia, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,374 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.