Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,378 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05722873Recruiting
Study intermittent fasting and its effects on metabolism
This study looks at how intermittent fasting affects your body's “metabolism” (how you use food and manage blood sugar/fats). It may help researchers understand whether this eating pattern changes metabolic health in people at higher risk for type 2 diabetes.
Pittsburgh, PennsylvaniaAges 21–45 - NCT04838249Recruiting
Hormone therapy study on eating, energy, and heart health
This study looks at how cross-sex hormone therapy affects appetite (eating behavior), metabolism (how your body uses food), energy balance, and cardiovascular (heart and blood vessel) health. You may be included if you meet specific health and safety requirements and can follow study procedures.
Leipzig, SaxonyAges 18 years+ - NCT04885322Recruiting
Brain stimulation trial for attention and thinking control
This study tests whether a non-painful brain stimulation method (tDCS) can improve attention and “thinking control,” and how brain activity changes during tasks. It also uses brain imaging (MRI), so safety and comfort conditions must be met.
Sacramento, CaliforniaAges 18–50 - NCT05298748Recruiting
Audio recordings to help breathing control mature in preterm babies
This trial studies whether listening to special “womb” sounds can help a preterm baby’s breathing control develop as they grow. It may help babies who are already breathing on their own (with low or no extra oxygen support).
Cleveland, OhioAges 1 week–1 month - NCT05691491RecruitingPhase 1/Phase 2
Temozolomide plus M1774 for advanced metastatic cancers
This Phase 1/2 trial tests a combination of temozolomide and M1774 to see how safe it is and whether it can help shrink advanced cancers that have spread. It focuses on certain tumor types and specific biomarker results, and it may be an option if standard treatments have been tried or aren’t possible.
Irvine, CaliforniaAges 18 years+ - NCT05691465RecruitingPhase 2
Radiation drug for metastatic prostate cancer with neuroendocrine cells
This Phase 2 study tests whether a radioactive medicine called lutetium Lu 177 dotatate is safe and effective for metastatic prostate cancer that has neuroendocrine features. It also checks whether patients’ scans show the cancer absorbs the drug (a requirement to start treatment).
Duarte, CaliforniaAges 18 years+ - NCT05689372Enrolling by invitation
Ozempic safety and effectiveness after launch in type 2 diabetes
This study tracks how Ozempic works and whether it stays safe for people with type 2 diabetes in everyday clinic care in Korea. You join because your doctor decides you should start Ozempic, and the study mainly monitors outcomes.
Jeonlabuk-doAges 19 years+ - NCT05696561Recruiting
Testing a glaucoma procedure called canaloplasty device
This trial studies whether a canaloplasty device is safe and effective for people with open-angle glaucoma who are planning cataract surgery. It may help lower eye pressure when using eye drops is being reduced or stopped.
SantiagoAges 22 years+ - NCT05701982Recruiting
Walking plus Tai Chi coach via video for COPD and pain
This study tests whether a phone/computer program that combines walking training with Tai Chi improves physical function (how well you move) in people who have COPD and long-term body or muscle pain. It may help you build strength, balance, and safer movement—especially if pain makes activity hard.
Boston, MassachusettsAges 40–100 - NCT05678556Recruiting
Relationship education to help prevent HIV in gay and bisexual men
This trial tests a relationship education program to help reduce HIV risk by supporting safer sex choices. It is for people who are currently at higher risk and are HIV-negative.
Chicago, IllinoisAges 16–34 - NCT05678699Recruiting
How Medicaid programs affect serious pregnancy complications
This study looks at how Medicaid rules and programs affect serious health problems during pregnancy and after birth. It may include women on Medicaid and also doulas and health-plan leaders, to help improve care for mothers.
Pittsburgh, PennsylvaniaAges Any age - NCT05675332Recruiting
Study tests how stereotype stress affects brain and impulsivity
This study looks at how feeling judged or stereotyped can affect impulsivity (acting without thinking) and how that connects to alcohol use. You may do an MRI brain scan, and it helps researchers understand these effects in African Americans.
New York, New YorkAges 21–35 - NCT05703425RecruitingPhase 2
Sulfasalazine in pregnancy to change stress hormone levels
This Phase 2 study tests whether sulfasalazine, a medicine taken by mouth, can lower a pregnancy stress hormone called CRH in pregnant people. It’s aimed at people at higher risk for preterm birth, to see if the hormone change might be helpful.
New Brunswick, New JerseyAges 18 years+ - NCT05708508RecruitingPhase 3
Immune-guided vs universal medicine to prevent CMV after kidney transplant
This study compares two strategies to prevent a viral infection called CMV after kidney transplant. It tests whether an “immune-guided” approach (using your immune test results) can prevent CMV as well as or better than giving preventive antiviral medicine to everyone.
RouenAges 18–75 - NCT05701969RecruitingEarly Phase 1
Melatonin for sleep during night shifts in residents
This early study tests whether melatonin can improve sleep patterns for doctors-in-training during overnight “night float” shifts. It may help you feel more rested and adjust to night work.
Charlottesville, VirginiaAges 18 years+ - NCT05703412Enrolling by invitation
Text or app check-ins after discharge for serious mental illness
This study tests an mHealth (phone-based) program that helps people with serious mental illness after leaving the hospital. It may help you stay connected to care and support in the community after discharge.
Providence, Rhode IslandAges 18 years+ - NCT05675345Recruiting
Negative pressure breathing device for sudden low-oxygen breathing failure
This trial studies a continuous negative external pressure device (a “cuirass” that helps breathing) for people with sudden, severe low oxygen levels. It aims to see whether the device improves breathing and oxygen levels without needing immediate intubation.
Brooklyn, New YorkAges 18 years+ - NCT05707871RecruitingEarly Phase 1
Testing how low-nicotine cigarettes affect heart measurements
This early study checks whether very low-nicotine cigarettes change heart-related measurements during a lab visit. It may help researchers understand how lowering nicotine could affect cardiovascular (heart and blood vessel) function.
Winston-Salem, North CarolinaAges 21 years+ - NCT05681299RecruitingPhase 4
Testing growth hormone and liraglutide effects on hunger hormones
This study tests how growth hormone (GH) and liraglutide affect a hunger-related hormone system called AgRP. It compares effects in healthy people (lean or overweight) and in people with isolated GH deficiency, aiming to understand how these treatments change appetite and metabolism.
New York, New YorkAges 18–45 - NCT05699174RecruitingPhase 3
Compare two antibiotic routes for infected broken bones after surgery
This Phase 3 trial tests whether giving antibiotics by mouth (PO) works as well as giving antibiotics through a vein (IV) for an infected fracture that has not healed after prior surgery. It may help you understand which approach is safer and more effective for getting the bone to heal.
Indianapolis, IndianaAges 18 years+ - NCT05688579Enrolling by invitationPhase 4
Testing an aldosterone-blocking medicine in hard-to-control hypertension
This trial studies whether a medicine that blocks aldosterone (called an MRA) can improve cardiovascular outcomes in people with high aldosterone levels and high blood pressure. You may be asked to take the study medicine and have blood pressure, heart, and lab tests monitored over time.
Ürümqi, XinjiangAges 30–75 - NCT05708443Recruiting
Exercise training to improve walking and daily activities in COPD
This trial studies whether doing a combination of endurance exercises can help people with COPD walk better and do everyday activities with less limitation. It compares an exercise approach aimed at improving walking function and daily movement.
Lumezzane, BresciaAges Any age - NCT05681572RecruitingPhase 3
Sedation before surgery to help kids feel better after anesthesia
This study tests whether giving a calming medicine before general anesthesia improves how children feel and experience anesthesia afterward. The goal is to see which pre-surgery approach works best and is comfortable for kids.
Montpellier, MontpellierAges 7–18 - NCT05706155Recruiting
Switching some animal protein to plant protein for Type 2 diabetes
This study tests whether replacing part of your animal protein with plant-based protein can improve Type 2 diabetes control. It may help your blood sugar and weight management without changing everything about your diet.
Porto Alegre, Rio Grande do SulAges 18–65
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,378 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.