Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,378 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05635175Recruiting
Hip abductor training for women with stress urine leakage
This trial tests whether specific hip muscle exercises can reduce stress urinary incontinence (urine leaks with activities like coughing or exercise). If it works, it could improve bladder control using perineal (pelvic-area) rehabilitation plus hip-focused training.
CaenAges 18 years+ - NCT05563766RecruitingPhase 2
Itraconazole with standard treatment for esophageal cancer
This trial tests whether adding the antifungal drug itraconazole to the usual chemotherapy and radiation before surgery can improve the chance of no cancer cells remaining at surgery. It is for patients with esophageal or gastroesophageal junction cancer that can be surgically removed.
Palo Alto, CaliforniaAges 18 years+ - NCT05585411Recruiting
Pacemaker type test to reduce heart worsening and death risk
This study compares two pacemaker pacing strategies—left-sided “bundle branch area” pacing versus right-sided ventricular pacing. It aims to see which approach better prevents heart failure getting worse and reduces abnormal timing between heart chambers over time.
Bucheon-siAges 19 years+ - NCT05584046Recruiting
Herbal patch for heel pain
This trial tests a new herbal patch for treating heel pain (plantar fasciitis). The patch is applied to the skin, and the study aims to see if it helps reduce pain.
ShatinAges 18–70 - NCT05591326Enrolling by invitation
Injectable platelet-rich fibrin to close gum recession
This trial tests whether an injectable healing material called platelet-rich fibrin can help cover exposed tooth root in front teeth with gum recession. If it works, it may reduce tooth sensitivity and improve appearance for people with suitable, healthy teeth and gums.
KütahyaAges 18–65 - NCT05586360RecruitingPhase 2
Testing how a statin may change immune markers in prostate cancer
This Phase 2 study tests whether taking simvastatin can change “immune regulation” markers in men with intermediate- to high-risk localized prostate cancer. It also looks at whether this could help lower the risk of cancer coming back after planned prostate surgery.
Atlanta, GeorgiaAges 18 years+ - NCT05588115Recruiting
Test blood biomarkers to help diagnose concussion
This study checks whether a blood test can accurately and quickly identify an uncomplicated concussion. It may help doctors confirm concussion sooner and more reliably, and potentially reduce time and cost of diagnosis.
Calgary, AlbertaAges 18–65 - NCT05557864Recruiting
Brain scan study for Parkinson’s patients with deep brain stimulators
This study looks at how the location of a deep brain stimulator in Parkinson’s disease affects movement problems. It mainly uses advanced 7T brain imaging to compare brain activity and motor symptoms.
Minneapolis, MinnesotaAges 21–89 - NCT05554107Recruiting
Physical activity study for POTS symptoms
This study looks at how physical activity affects symptoms in people with POTS (a condition where heart rate rises when standing). If you have POTS, you may be asked to participate and help the researchers understand whether exercise changes how you feel.
MalmöAges 18 years+ - NCT05550415RecruitingPhase 2
Simvastatin with chemotherapy for triple-negative breast cancer
This trial studies whether adding simvastatin (a cholesterol medicine) can slow or change how breast cancer spreads in triple-negative breast cancer. It compares outcomes while you receive planned chemotherapy, and you may or may not be taking simvastatin as part of the study treatment.
Jakarta Pusat, DKI JakartaAges 18 years+ - NCT05555485Recruiting
Check if ear stimulation can help chronic pain and reduce opioids
This study tests whether a device that stimulates the ear (through the skin) can reduce chronic pain and help people lower their opioid pain medicine. It may help you manage pain with less opioid use if you meet their safety and medication criteria.
Galveston, TexasAges 18–65 - NCT05556655Recruiting
Brain stimulation and how it changes memory task performance
This study tests how a brain stimulation method affects how well you do thinking and memory tasks. You would complete cognitive testing before and after the stimulation, and the researchers look at whether your performance changes.
Fort Collins, ColoradoAges 18–65 - NCT05551559Enrolling by invitation
How bariatric surgery changes liver metabolism in fatty liver disease
This study looks at how bariatric (weight-loss) surgery affects how your liver processes nutrients in people with non-alcoholic fatty liver disease. It may help researchers understand what changes in the body after surgery and whether that could guide better future care.
HelsinkiAges 18–75 - NCT05578300Recruiting
Translating thrombectomy care into real-world practice in Asia-Pacific
This study aims to help endovascular thrombectomy for certain severe strokes work well in everyday hospital care across Asia-Pacific. You may be considered if you’re an adult with a specific type of stroke blocked in a major brain blood vessel.
Linyi, ShandongAges 18 years+ - NCT05561361Recruiting
Test treatment for primary aldosteronism and blood vessel function
This trial studies whether a specific treatment (related to spironolactone/aldosterone support) can improve how well your blood vessels work in people with primary aldosteronism. It may help reduce blood pressure risk by improving blood vessel health.
NanchangAges 18–75 - NCT05568719RecruitingPhase 3
Testing gene therapy for hemophilia A or B
This Phase 3 trial is checking how safe and effective two gene therapies are for people with hemophilia A or hemophilia B. It only includes people who already received the study medicines through specific Pfizer studies, so it’s mainly for that existing participant group.
Rancho Cordova, CaliforniaAges 18 years+ - NCT05556460Recruiting
Device trial for fixing severe tricuspid valve leakage without surgery
This trial tests the DragonFly-T system to improve symptoms and heart function in people with severe tricuspid regurgitation (a leaky heart valve) using a catheter-based repair. It may help reduce valve leak–related symptoms when standard medication isn’t enough and surgery risk is higher.
Chengdu, SichuanAges 18 years+ - NCT05183074Recruiting
MRI-guided focused radiation for prostate cancer
This trial tests a newer way to plan and deliver radiation for prostate cancer using real-time MRI guidance. It may help by aiming high-dose treatment precisely while treating nearby disease and (in some cases) limited metastatic spots.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05224934Recruiting
Radiation before surgery for retroperitoneal soft-tissue sarcoma
This trial tests giving a shorter, lower-dose radiation treatment before surgery for a retroperitoneal (deep belly/back space) soft-tissue sarcoma. The goal is to shrink or control the tumor and make surgery more effective and safe.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05545306Recruiting
Study tests how extra calories change your daily energy use
This study looks at how eating more calories affects your body’s natural heat production and total energy use over a full day. It may help researchers better understand how the body manages weight and energy.
Phoenix, ArizonaAges 18–60 - NCT05536076Recruiting
Breathing treatment to help recovery after spinal cord injury
This study tests whether a breathing-support treatment (for abnormal breathing during sleep) can improve breathing recovery in people living with a spinal cord injury. It aims to see if treating higher carbon dioxide levels and sleep-breathing problems leads to better breathing and recovery.
Detroit, MichiganAges 18–89 - NCT05512169Recruiting
Genetic study in Indian children with newly diagnosed leukemia
This study looks at genetic (DNA) differences to understand acute lymphoblastic leukemia (ALL) in Indian children and how treatments may fit better. You may be able to join if your child is newly diagnosed, meets the study’s treatment plan rules, and provides consent.
New DelhiAges 1–18 - NCT05527548RecruitingPhase 4
Alendronate for knee recovery after ACL surgery
This trial tests whether alendronate, a drug commonly used for bone health, can improve knee function and recovery after ACL surgery. It is for people having their first ACL repair.
ShatinAges 14 years+ - NCT05514899RecruitingPhase 2
Cannabidiol and THC study for gut health and brain inflammation in HIV
This Phase 2 study tests whether cannabidiol (CBD) and tetrahydrocannabinol (THC) change the gut microbiome and brain-related inflammation in people with HIV. It may help researchers understand new ways to reduce inflammation, but you would need strict cannabis and CBD/THC avoidance during the study.
San Diego, CaliforniaAges 21–70
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,378 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.