Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,864 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06026904Enrolling by invitation
Testing vagus nerve stimulation for motivation in depression
This trial tests if a gentle nerve stimulation device can improve motivation and interest in people with depression and a lack of pleasure or drive. You keep taking your usual antidepressant pill during the study.
Hefei, AnhuiAges 18–60 - NCT05987735Enrolling by invitation
Blame-Less program for trauma-related shame and guilt
This study tests a 7-week psychoeducation program called BLAME-LESS to help people who feel guilt or shame after a traumatic event. It aims to reduce these feelings by providing clear information on trauma responses.
Almelo, OverijsselAges 12–18 - NCT05975437Enrolling by invitation
Personalized follow-up care after breast cancer treatment
This trial tests whether a personalized follow-up plan after breast cancer surgery (instead of a fixed schedule) can improve care and support after treatment. It may help people know what follow-up is best for them as they move into survivorship.
Apeldoorn, GelderlandAges 40 years+ - NCT05961501Enrolling by invitationPhase 2/Phase 3
CBD and CBN for long-lasting facial pain and muscle headaches
This trial tests whether CBD and CBN can reduce facial pain and headaches caused by muscle-related problems that have lasted more than 3 months. It may help people who have ongoing symptoms find a new treatment option.
WroclawAges 18 years+ - NCT05932615Enrolling by invitation
Testing a new transcatheter valve for aortic valve narrowing
This trial studies how safe and effective the NAVITOR valve is for treating narrowed aortic valves placed through a catheter (no open-heart surgery). It may be an option if you’re at intermediate-to-low surgical risk and meet heart ultrasound/CT measurements.
Birmingham, AlabamaAges 18 years+ - NCT05869734Enrolling by invitation
Conservative care to improve urinary symptoms and sleep in diabetes
This study looks at a non-surgical (“conservative”) approach to help women with diabetes who have bladder-related urinary symptoms and poor sleep. It aims to see whether these symptoms improve at the same time, helping quality of life.
New Taipei CityAges 20–79 - NCT05806112Enrolling by invitation
Improve staff well-being programs for residential care workers
This trial tests whether specific programs can reduce burnout and improve resiliency (coping strength) among staff who work in behavioral health group homes. It may help workers feel better and handle stressful work days.
Boston, MassachusettsAges 18 years+ - NCT05740462Enrolling by invitation
Does hydroponic fortified food improve iron and B12 levels
This study tests whether eating specially grown, vitamin- and mineral-fortified salad greens helps improve nutrient levels—especially iron—in people who follow vegetarian or vegan diets. You may also be asked to use a diet app during the study.
NorwichAges 18–60 - NCT05703412Enrolling by invitation
Text or app check-ins after discharge for serious mental illness
This study tests an mHealth (phone-based) program that helps people with serious mental illness after leaving the hospital. It may help you stay connected to care and support in the community after discharge.
Providence, Rhode IslandAges 18 years+ - NCT05689372Enrolling by invitation
Ozempic safety and effectiveness after launch in type 2 diabetes
This study tracks how Ozempic works and whether it stays safe for people with type 2 diabetes in everyday clinic care in Korea. You join because your doctor decides you should start Ozempic, and the study mainly monitors outcomes.
Jeonlabuk-doAges 19 years+ - NCT05688579Enrolling by invitationPhase 4
Testing an aldosterone-blocking medicine in hard-to-control hypertension
This trial studies whether a medicine that blocks aldosterone (called an MRA) can improve cardiovascular outcomes in people with high aldosterone levels and high blood pressure. You may be asked to take the study medicine and have blood pressure, heart, and lab tests monitored over time.
Ürümqi, XinjiangAges 30–75 - NCT05641987Enrolling by invitation
School staff well-being program survey study
This study tests an “educator well-being program” to see how it affects staff well-being. You may be able to participate if you work as school staff and are 18 or older when the survey is given.
Farmington, ConnecticutAges 18 years+ - NCT05626374Enrolling by invitation
Remote check-in tool to reduce dropout in training
This study tests whether adding a remote, self-report tool for distress (how overwhelmed or unwell someone feels) improves how many people complete a vocational training program. It’s meant to support people using the usual case management, but with extra remote check-ins.
Barrie, OntarioAges 18–49 - NCT05606991Enrolling by invitation
Testing how CPAP affects brain waste clearance during sleep
This study looks at how stopping CPAP for 14 nights affects “brain waste clearance,” a process your brain uses to clear byproducts during sleep. It is testing whether using CPAP versus stopping it changes this brain cleanup in adults with severe obstructive sleep apnea (OSA).
Macquarie Park, New South WalesAges 35–65 - NCT05602181Enrolling by invitation
ALL app to help kids who use AAC learn reading
This study tests an iPad app (ALL) designed to improve early reading skills in children who use AAC to communicate. It may help children build letter sounds, word skills, and spelling, with school support helping the app be used consistently.
State College, PennsylvaniaAges 3–10 - NCT05600868Enrolling by invitation
Testing dual attention during EMDR therapy for PTSD
This study tests whether adding “dual attention” to EMDR therapy helps people with high PTSD symptoms. If you have significant PTSD symptoms, this approach may improve how well the therapy works, but it depends on safety and recent treatment history.
Pozuelo de Alarcón, MadridAges 18–65 - NCT05591326Enrolling by invitation
Injectable platelet-rich fibrin to close gum recession
This trial tests whether an injectable healing material called platelet-rich fibrin can help cover exposed tooth root in front teeth with gum recession. If it works, it may reduce tooth sensitivity and improve appearance for people with suitable, healthy teeth and gums.
KütahyaAges 18–65 - NCT05551559Enrolling by invitation
How bariatric surgery changes liver metabolism in fatty liver disease
This study looks at how bariatric (weight-loss) surgery affects how your liver processes nutrients in people with non-alcoholic fatty liver disease. It may help researchers understand what changes in the body after surgery and whether that could guide better future care.
HelsinkiAges 18–75 - NCT05453240Enrolling by invitation
Check long-term safety of an LVIS brain stent
This study looks at how safe and effective the LVIS device is over the long term. It mainly includes adults who had an LVIS stent placed for certain types of brain aneurysms within the past 5 years, using the approved indications.
Aliso Viejo, CaliforniaAges 18 years+ - NCT05448768Enrolling by invitation
Testing brain stimulation in people with mild memory problems
This study tests a brain stimulation approach (TBS) to see if it can improve thinking and memory in people with mild cognitive impairment. It may also explore why it works by looking at brain-related measurements after TBS.
TaoyuanAges 50–90 - NCT05407415Enrolling by invitation
Using a phone ECG monitor to improve care for atrial fibrillation
This trial studies whether sending heart rhythm recordings from a phone (using the KardiaMobile ECG device) can improve health care use and patient experience for people with atrial fibrillation. It may help your care team monitor you more smoothly—if you meet the study requirements.
Chicago, IllinoisAges 18–90 - NCT05374291Enrolling by invitationPhase 3
Dapagliflozin trial for kidney and heart outcomes in severe CKD
This study tests whether dapagliflozin can improve kidney and heart-related outcomes in people with severe chronic kidney disease (CKD). You would take the study medicine (or a comparison treatment) and be followed to see how your kidneys and heart do over time.
Canberra, Australian Capital TeritoryAges 18 years+ - NCT05313464Enrolling by invitation
Parental feeding by tube to improve parent-child interaction
This study looks at whether giving a child nutrition through a tube affects how parents and children interact. The goal is to see if the feeding approach helps parent-child connection and daily interaction.
Créteil, Val-deMarneAges 7 months–7 months - NCT05215886Enrolling by invitation
Bariatric surgery and memory problems in people with obesity
This study looks at how bariatric (weight-loss) surgery may affect memory and thinking in people with obesity who already have memory decline or dementia. It may help doctors understand which patients benefit most and what changes to expect.
Sacramento, CaliforniaAges 18–75
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,864 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.