Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,863 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05179759Enrolling by invitation
School and teacher program for early grades in rural India
This study tests a school/teacher approach (rolled out in real school settings) to improve teaching for early primary students. It will include rural primary schools and the teachers and students in classrooms for grades 1–4.
Darjeeling, West BengalAges 5 years+ - NCT05110833Enrolling by invitation
Study dosing effects during monitored neck or chest spine surgery
This trial studies whether different medication dosing during monitored neck or upper chest spine surgery leads to better outcomes. You might help doctors figure out the most effective dosing approach for this type of surgery.
Minneapolis, MinnesotaAges 18 years+ - NCT05101746Enrolling by invitationPhase 2/Phase 3
Nitric oxide to protect brain and kidneys in babies during heart surgery
This trial studies whether giving nitric oxide during heart-lung bypass surgery can help protect a baby’s brain and kidneys. If you qualify, the study team will check outcomes after surgery to see if benefits happen compared with usual care.
Nashville, TennesseeAges birth–1 year - NCT05029115Enrolling by invitation
SGLT2 pill study for atrial fibrillation with type 2 diabetes
This trial tests whether an SGLT2 inhibitor pill can help people who have atrial fibrillation (an irregular heartbeat) and type 2 diabetes. You may be eligible if you’re in the right age range, on diabetes pills only, and meet specific heart and lab criteria.
Yangcheon, SeoulAges 20–80 - NCT04788628Enrolling by invitation
Sound stimulation study for sleep and memory in epilepsy
This trial studies whether carefully timed sound (“auditory stimulation”) can change sleep patterns and memory in people with epilepsy. It may help researchers understand how to improve thinking and memory by adjusting how the brain sleeps.
Boston, MassachusettsAges 12–65 - NCT04691518Enrolling by invitation
Testing intermittent low-oxygen sessions in healthy adults
This study tests whether breathing lower-oxygen air in short breaks changes how the brain and body respond. It is only for medically stable, healthy adults with specific safety screening.
Chicago, IllinoisAges 18–70 - NCT04684901Enrolling by invitation
AlloWrap to reduce inflammation during cervical spine fusion surgery
This trial tests whether AlloWrap® can lower inflammation during anterior cervical fusion surgery (ACDF). It may help improve healing and recovery by reducing the body’s inflammatory response after surgery.
San Diego, CaliforniaAges 18 years+ - NCT04619836Enrolling by invitation
Study of diabetes care plans and cost-effectiveness
This trial looks at how well a diabetes care plan works and how cost-effective it is for people with type 2 diabetes. You may be included if your diabetes care and self-management are arranged using a specific care-planning approach.
TampereAges 18–90 - NCT04504955Enrolling by invitation
Atopic dermatitis patient registry for medication safety and results
This study is a real-world registry that collects information from adults with atopic dermatitis (eczema) to track how newly started treatments work and how safe they are over time. It may help researchers and doctors better understand medication effects in everyday care.
Waltham, MassachusettsAges 18 years+ - NCT04504721Enrolling by invitation
Light therapy for fibromyalgia using blue-enriched white light
This study tests whether a specific type of light (blue-enriched white light) can reduce symptoms of fibromyalgia. It may help people feel better by changing how the body responds to light.
TaipeiAges 20–64 - NCT04451044Enrolling by invitation
Guided heart stent planning using an inside pressure sensor
This study tests whether using a tiny pressure sensor in heart arteries during a procedure can better guide where to place a stent. It may help doctors choose the safest and most effective stent plan by more accurately measuring artery narrowing.
Birmingham, AlabamaAges 18 years+ - NCT04444362Enrolling by invitation
Probacine to protect organs after cardiovascular surgery
This study tests whether a medicine called Probacine can help protect your gut and organs after cardiovascular surgery. If you qualify, you may be asked to take part and follow the study plan to see if complications are reduced.
Beijing, Beijing MunicipalityAges 18–90 - NCT04258774Enrolling by invitation
Breathing challenge during MRI to test brain blood-flow signals
This study uses a breathing challenge while you’re in an MRI to see how blood flow signals in the brain change. It may help researchers better understand how brain imaging signals respond to breathing and oxygen/carbon dioxide levels.
St Louis, MissouriAges 18 years+ - NCT04251429Enrolling by invitation
Healthy workplace program for public healthcare workers
This trial studies a workplace program delivered by trained peers to improve health in public-sector healthcare facilities. You may be able to join if you are a direct employee of the agency that runs the facility.
Ages 18 years+ - NCT04165460Enrolling by invitation
CBT programs for anxiety and coping in cervical cancer
This study tests two structured talk-therapy programs (cognitive-behavioral therapy) to help people with cervical cancer manage anxiety, depression symptoms, and unhelpful coping skills. It also looks at the role of a main caregiver during care planning and support.
Mexico City, TlalpanAges 18 years+ - NCT04085913Enrolling by invitationEarly Phase 1
Test shot to reduce opioid use after thyroid or parathyroid surgery
This early-phase study tests whether an injection given during thyroid or parathyroid surgery can lower how much opioid pain medicine you need afterward. It may help some people manage pain with less opioid medication.
Columbia, MissouriAges 18 years+ - NCT03984591Enrolling by invitationPhase 4
Compare spironolactone vs eplerenone for heart failure patients
This study uses Denmark’s heart failure registry to compare two common tablet medicines—spironolactone and eplerenone—for people with symptomatic systolic heart failure. It aims to see which one leads to better health outcomes over time.
CopenhagenAges Any age - NCT03692455Enrolling by invitation
Compare two weight-loss surgeries for reflux over 8 years
This study follows people for up to 8 years to see how two different weight-loss surgeries affect ongoing heartburn and acid reflux. You would join only if you were already enrolled in an earlier related study and can complete required follow-up visits and tests.
Passo Fundo, Rio Grande do SulAges 18–78 - NCT03687710Enrolling by invitation
Alzheimer’s registry for people with memory concerns or risk
This is a research registry that helps doctors compare how different memory and Alzheimer’s risk groups change over time. It may help researchers learn which people are more likely to develop Alzheimer’s and how to better track early changes.
New York, New YorkAges 18–99 - NCT03395509Enrolling by invitation
Free screening program for diabetes and heart risks
This study looks at how well and how cost-effective a combined health screening is for diabetes and cardiovascular (heart and blood vessel) risks. You may be invited to attend screening around your 67th birthday.
ViborgAges 67–67 - NCT03384927Enrolling by invitation
Dairy intake study for muscle stiffness in spasticity
This trial looks at whether eating dairy can reduce spasticity, or muscle stiffness/tightness. It’s testing dairy as an add-on by comparing your muscle symptoms and treatment goals during the study.
Glostrup MunicipalityAges Any age - NCT03101722Enrolling by invitation
Huperzine A for hearing loss, tinnitus, and mild memory issues
This trial tests whether huperzine A can improve hearing-related symptoms along with tinnitus (ringing) and mild cognitive (memory/thinking) problems. If you have mild-to-moderate hearing loss plus bothersome constant tinnitus and some cognitive decline, this study may help researchers see if the treatment makes a difference.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT03032601Enrolling by invitation
N-acetyl cysteine study for people with multiple sclerosis
This study tests whether N-acetyl cysteine (a supplement-like medicine) changes body and brain function in people with multiple sclerosis. It may help researchers understand how it affects brain chemistry and activity using special brain imaging.
Philadelphia, PennsylvaniaAges 18 years+
Hear when a new Effectiveness trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,863 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.