Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,871 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03810794Recruiting
Acupuncture study for people with Alzheimer’s memory problems
This trial tests whether acupuncture can improve symptoms in people with Alzheimer’s disease. You may qualify if you have memory and thinking changes consistent with Alzheimer’s and meet imaging and brain-scan score requirements.
Shanghai, Shanghai MunicipalityAges 50–85 - NCT03818178Recruiting
Study of gut-delivered fats and insulin resistance
This study looks at how sending certain fats through the intestine affects “insulin resistance,” a condition where the body doesn’t use insulin as well. If you qualify, you may receive a controlled lipid (fat) delivery as part of measuring body fat handling and related body chemistry.
Rochester, MinnesotaAges 18–55 - NCT03821857RecruitingPhase 4
Study of hormone disruption effects on aging and Alzheimer’s
This trial studies how hormone (endocrine) disruption may affect aging and Alzheimer’s disease in women. It may help researchers understand why these effects can differ by sex and how to better assess or track risk over time.
Jacksonville, FloridaAges 60 years+ - NCT03845036Recruiting
Diet and exercise study for leg circulation problems
This study looks at how diet changes and an exercise program may improve walking and leg symptoms in people with peripheral artery disease (PAD). You may be eligible if you have a history of claudication (leg pain with walking) and tests or treatment history show PAD.
Oklahoma City, OklahomaAges 40 years+ - NCT03851627RecruitingPhase 4
Testosterone for fatty liver in overweight men with diabetes
This trial compares testosterone undecanoate versus a placebo (inactive pill) to see if it lowers fat in the liver measured by MRI. It focuses on overweight or obese men who have prediabetes or type 2 diabetes and low testosterone confirmed by blood tests.
ViennaAges 18–75 - NCT03865290RecruitingPhase 2
Ondansetron for stomach nerve and motion problems in diabetes
This trial tests whether ondansetron can improve stomach “sensorimotor” problems—how the gut senses food and moves it—especially in people with diabetes and troubling indigestion. It may help reduce symptoms like early fullness, nausea, and discomfort after eating.
Rochester, MinnesotaAges 18–75 - NCT03878706Recruiting
Testing diabetes medicines on heart risk and heart failure
This trial studies how diabetes medicines (GLP-1 and SGLT2, alone or together) affect the heart in people with type 2 diabetes who are at higher cardiovascular risk and have heart failure with preserved pumping function. It may help find safer or more effective ways to reduce heart problems.
Athens, AtticaAges 45–80 - NCT03883269RecruitingPhase 4
Tests topical antibiotics’ anti-inflammatory effect in acne
This trial studies whether putting antibiotic creams on mild-to-moderate facial acne reduces inflammation. It may help answer whether topical erythromycin or clindamycin can improve acne-related redness and swelling.
LeidenAges 18–45 - NCT03886961Recruiting
Reflux band device trial for lung transplant recipients
This trial tests whether a Reflux Band™ placed around the upper swallowing tube area can reduce reflux (stomach acid coming up) in people who have had a lung transplant. If reflux is causing discomfort or lung irritation, reducing it may help you stay stable after transplant.
Gainesville, FloridaAges 18–80 - NCT03902912RecruitingPhase 3
Prednisolone treatment to help women after repeated miscarriages
This trial tests whether taking prednisolone, a steroid medicine, can improve immune cell activity in the uterus in women who have had 3 or more miscarriages. If it works, it could help reduce the chance of future pregnancy loss.
Hong KongAges 18–40 - NCT03906253Recruiting
Laser treatment to prevent skin growth in older adults
This trial tests whether a type of laser treatment can help protect older adults’ skin from turning actinic keratosis (a sun-related precancer) into more serious skin problems. It focuses on the forearms and may help reduce future skin damage while checking safety and comfort.
Dayton, OhioAges 60 years+ - NCT03914378Recruiting
Study how radiation and cisplatin affect hearing in head and neck cancer
This study looks at how radiotherapy, and possibly cisplatin chemotherapy, affect hearing in people treated for head and neck cancer. It may help doctors better predict hearing side effects and plan hearing monitoring or prevention.
ManchesterAges 18 years+ - NCT03918408RecruitingPhase 1
Platinum eye drops and light to slow keratoconus
This Phase 1 study tests whether a specific corneal cross-linking system (called PXL-Platinum 330) is safe and effective for people with progressive keratoconus, a condition that makes the cornea thin and bulge. The goal is to slow vision changes and see how well the treatment works in the short term.
Eugene, OregonAges 12–45 - NCT03935646RecruitingPhase 2
Test of Adderall’s short-term effects in college students with ADHD
This study measures how stimulant medication (Adderall) affects college students with ADHD in the short term. It compares people with ADHD to students without ADHD to see what changes you may notice during the study.
Laramie, WyomingAges 18–29 - NCT03949400Recruiting
Exercise therapy and a soft knee brace for knee arthritis
This study tests whether an exercise program plus education, along with a soft brace, helps improve symptoms and function in adults with knee osteoarthritis. It may help people who have knee pain by combining movement training with daily support.
Aalborg, NothernAges 18 years+ - NCT03973268RecruitingPhase 1
Ketamine study to understand treatment response in hard-to-treat depression
This early-stage study tests ketamine and looks at what brain changes may explain why it helps people with major depression that hasn’t improved with usual treatments. You may be asked to stay in the hospital and complete detailed interviews, mood rating scales, and brain imaging.
Bethesda, MarylandAges 18–70 - NCT03979235Recruiting
Rehab effectiveness programs for people after stroke
This trial is testing rehabilitation programs by studying how well they work for people with movement problems after a stroke. You may be able to join if you can complete the rehab assessment and follow testing instructions.
BeijingAges 18–80 - NCT03980457Recruiting
Exoskeleton walking therapy for stroke recovery
This trial studies whether assisted walking training with an exoskeleton can improve recovery after stroke, especially for walking and daily function. You may be offered therapy once you are medically stable, able to stand, and able to participate safely.
Oklahoma City, OklahomaAges 18–90 - NCT03997643RecruitingPhase 2
Radiation plan trial to help protect swallowing after mouth cancer
This Phase 2 study tests whether changing the “radiation volume” (how much area is treated) can better preserve swallowing after surgery for oral cavity squamous cell cancer. It may help reduce swallowing problems while still treating the cancer safely.
Miami, FloridaAges 18 years+ - NCT07652398Recruiting
Comparing passive recovery after intense cycling
This study compares different ways to recover after a very hard cycling workout—like rest, massage, or special tape. It looks at which method helps you bounce back fastest.
DenizliAges 18–30 - NCT07703722RecruitingPhase 3
Psilocybin and therapy for depression with trauma
This trial tests psilocybin (a compound from certain mushrooms) combined with a structured therapy to see if it helps people with depression linked to trauma. It focuses on how the treatment affects the connection between the gut and brain.
Islamabad, CapitalAges 18–60 - NCT07702487Recruiting
Warming before kidney surgery study
This trial tests if warming the body before kidney surgery can lower lactate levels, which may help recovery. It is for adults scheduled for a planned (not emergency) kidney removal.
Istanbul, SisliAges 18–90 - NCT07542600Recruiting
Spa therapy to help women with infertility after embryo transfer
This study tests whether spa-based rehabilitation—including thermal water treatments and relaxation therapies—may improve fertility outcomes in women who have had unsuccessful embryo transfers. Researchers hope it might help prepare the body for pregnancy.
Františkovy Lázně, Carlsbad RegionAges 20–40 - NCT07703371Recruiting
Kodo millet porridge and its effect on gut health and metabolic syndrome
This study tests whether eating Kodo millet porridge every day for 12 weeks can improve gut health and reduce risk factors for metabolic syndrome (like being overweight). If you are between 20 and 60 years old, are overweight or obese, and are willing to eat the porridge daily without changing your diet or exercise, you may be able to join.
Mysore, KarnatakaAges 20–60
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,871 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.