Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,871 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03494374Recruiting
Foot brace and exercise for flat feet
This trial looks at whether using a foot brace (an orthosis) plus exercises can improve symptoms from flat feet. It may help by changing how your foot and heel work when you stand or walk.
Seongnam-si, Bundang-guAges 3–10 - NCT03498326RecruitingPhase 2
Gemcitabine plus celecoxib after pancreatic surgery
This trial tests whether adding celecoxib to gemcitabine chemotherapy after complete (R0) pancreatic tumor removal can lower the chance the cancer comes back. It may help people who have had successful surgery but still need anti-cancer treatment.
Hangzhou, ZhejiangAges 18–90 - NCT03544489Recruiting
Exercise program after ICD implant
This trial studies whether adding a structured exercise program after an ICD implant is safe and helpful for people with certain heart rhythm problems. You may qualify if you can comfortably walk daily and can follow the study schedule for several months.
Seattle, WashingtonAges 18 years+ - NCT03557619RecruitingPhase 1
Venetoclax test in women with specific non-Hodgkin lymphomas
This Phase 1 study tests how venetoclax affects certain hormone pills (ethinyl estradiol and levonorgestrel) in women with different non-Hodgkin lymphomas. It’s mainly looking at safety and drug interactions, which could help guide treatment for people who need hormone-based contraception.
Detroit, MichiganAges 18 years+ - NCT03574103Recruiting
Testing how fasting affects health in women with excess weight
This study looks at the long-term effects of fasting on the body in women who have a higher-than-average weight. It may help researchers understand potential benefits and risks of fasting, but it also requires you to meet several health and medication rules.
Belo Horizonte, Minas GeraisAges 18–59 - NCT03587701RecruitingPhase 2
Anakinra for steroid-resistant inner ear inflammation
This trial tests an anti-inflammatory drug (anakinra) in people whose inner-ear hearing problems have not improved with steroid treatment. It aims to reduce worsening hearing caused by autoimmune inner ear disease or difficult-to-control Meniere’s disease.
New Hyde Park, New YorkAges 18–75 - NCT03589729RecruitingPhase 2
Dexrazoxane to help protect the heart during blood-cancer chemo
This Phase 2 study tests dexrazoxane, a heart-protecting medicine, to reduce heart side effects from chemotherapy in people with certain blood cancers. If you qualify, you would receive dexrazoxane along with chemotherapy, and the team will monitor your heart function closely.
Houston, TexasAges 12 years+ - NCT03642002Recruiting
Music therapy for adults on breathing machines in the ICU
This trial tests whether music therapy can improve comfort and recovery for adults who need a breathing machine (mechanical ventilation) in the ICU for at least 48 hours. It may help with stress, mood, and other ICU-related symptoms while you are in critical care.
New York, New YorkAges 18 years+ - NCT03663790Recruiting
Gait retraining for knee osteoarthritis movement patterns
This trial tests whether a structured walking retraining program can improve how your leg moves if you have knee osteoarthritis. It may help reduce strain on your lower body during walking by changing walking technique.
Manassas, VirginiaAges 18–80 - NCT03685890RecruitingPhase 1/Phase 2
Testing nivolumab for melanoma spread to the limb skin
This trial studies nivolumab, an immune medicine, for melanoma that has spread to the skin along a limb (called in-transit metastases). It’s given after a procedure that delivers higher treatment levels to the affected limb, with the goal of shrinking the melanoma and improving outcomes.
AmsterdamAges 18 years+ - NCT03713424RecruitingPhase 2
Brain scan study of an antibiotic for drug addiction
This study uses an MRI brain scan to see how taking clavulanic acid affects brain activity related to drug addiction. It may help researchers understand whether this medicine could change how addiction-related cues affect the brain.
Columbia, MissouriAges 18–65 - NCT03718403RecruitingPhase 4
Theophylline trial for pseudohypoparathyroidism
This Phase 4 study tests whether the medicine theophylline can help people with pseudohypoparathyroidism type 1A or 1B. It may be considered if you’re trying to improve how your body uses parathyroid hormone and manage related calcium levels.
Boston, MassachusettsAges 5–21 - NCT03725527Recruiting
Nerve block test to improve breathing after belly surgery
This trial studies whether a numbing injection near the abdominal muscle (rectus sheath block) helps your breathing and diaphragm function after elective upper belly surgery. If you qualify, you may receive or not receive this pain/nerve block as part of the study.
Asyut, Assiut GovernorateAges 18–50 - NCT03736382Recruiting
Study how mild low-oxygen affects sleep apnea and blood pressure
This trial studies whether mild, controlled low oxygen during sleep can change sleep apnea symptoms and related blood pressure issues. It mainly looks at people with newly diagnosed, untreated sleep apnea and early high blood pressure.
Detroit, MichiganAges 18–60 - NCT03742687Recruiting
Testing a shorter, stronger radiation schedule for lung cancer
This trial studies a different way to deliver radiation to people with locally advanced, non-operable non-small cell lung cancer. It may help by aiming to treat the tumor effectively with a different radiation timing and dose pattern.
AarhusAges 18 years+ - NCT03753555RecruitingPhase 4
High-intensity statin treatment for certain stroke artery plaque cases
This trial tests whether a higher-dose statin can help after an ischemic stroke in people who have specific plaque patterns in brain blood vessels. It may help lower the risk of another stroke by targeting the artery plaque process.
ShenyangAges 18–80 - NCT03756961Recruiting
Opioid-free care plan for people having weight-loss surgery
This trial studies whether an opioid-free or opioid-sparing care pathway can improve comfort and outcomes for adults undergoing laparoscopic weight-loss surgery. It may help people avoid side effects from opioid pain medicines while still managing pain safely.
Lindesberg, Region ÖrebroAges 18 years+ - NCT03767426Recruiting
Study how sleep loss affects memory and emotions
This study looks at how losing sleep—and then getting recovery sleep—changes emotional memory and emotional reactions. It may help researchers understand why sleep affects mood and thinking, and what could improve these effects.
Boston, MassachusettsAges 18–35 - NCT03770923RecruitingPhase 3
Testing medicines for rheumatoid arthritis activity
This trial studies whether certain medicines can improve how active rheumatoid arthritis is. If you have rheumatoid arthritis and do not have significant liver or kidney problems, you may be able to join.
TantaAges 18 years+ - NCT03770936RecruitingPhase 3
Drugs to reduce liver scarring in chronic hepatitis C
This Phase 3 study tests medicines to see whether they can reduce liver scarring (fibrosis) in people with long-term hepatitis C. If you qualify, you may receive the study treatment and be monitored over time to see how your liver is affected.
TantaAges 20 years+ - NCT03775837Recruiting
Ginseng extract to improve abnormal liver blood tests
This trial studies whether a Panax ginseng extract can improve liver-related blood test results in adults. It may help people with mildly to moderately elevated liver enzymes, while carefully excluding people with other liver causes.
YangsanAges 19–75 - NCT03789552RecruitingPhase 3
Testing T89 to prevent chest pain during stable angina
This Phase 3 trial tests whether T89 reduces angina (chest pain caused by heart-related reduced blood flow) in people with stable angina. You may help confirm the treatment’s benefit by completing symptom tracking and exercise heart tests over several weeks.
Naples, FloridaAges 18–90 - NCT03797690Recruiting
Needle procedure for Dupuytren’s hand contracture
This trial looks at whether a minimally invasive needle procedure can improve hand stiffness caused by Dupuytren’s disease. It may help reduce finger bending that affects how you use your hand.
ParisAges 18 years+ - NCT03808337RecruitingPhase 2
SBRT radiation plus standard treatment for spread cancer
This trial looks at adding a focused radiation treatment called SBRT to standard care for cancers that have spread to a limited number of spots. It aims to control those spread-out tumors while still using the usual cancer treatment plan.
San Carlos, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,871 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.