Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07429266RecruitingPhase 3
Study of sapablursen for phlebotomy-dependent polycythemia vera
This trial tests an investigational drug called sapablursen for people with polycythemia vera who still need frequent phlebotomies. The goal is to see if the drug can reduce the need for blood removal and help control the disease safely.
Miami, FloridaAges 18 years+ - NCT07426120RecruitingPhase 3
Coumarin cream for psoriasis: a research study
This study tests a cream made from a natural plant compound (coumarin) to see if it can help treat plaque psoriasis. If you have mild-to-moderate psoriasis and haven't used certain other treatments recently, this trial may be an option for you.
New York, New YorkAges 18–70 - NCT07428538RecruitingPhase 3
Testing larsucosterol for severe alcohol-related hepatitis
This trial tests a new medicine called larsucosterol to see if it helps people with severe alcohol-related hepatitis (liver inflammation from heavy drinking). If you qualify, the study will monitor your safety and recovery over 90 days.
Birmingham, AlabamaAges 18 years+ - NCT07430917RecruitingPhase 2
Testing J147 for recent stroke from blocked artery
This trial tests a new drug, J147, for people who recently had a stroke caused by a blocked artery and have already had a procedure to reopen that artery. It aims to see if the drug can improve recovery.
Long Beach, CaliforniaAges 18–90 - NCT07431177RecruitingPhase 2
Study of an investigational drug for non-segmental vitiligo
This study tests an investigational drug (GIA632) in people with non-segmental vitiligo. It aims to see if different doses can safely and effectively restore color to white patches.
Birmingham, AlabamaAges 18–99 - NCT07435142Recruiting
Urine-derived cells for corneal eye disease
This trial tests if using special cells from your own urine can help repair the inner layer of your cornea (the clear front part of your eye). It may be an option if you have damage to these cells and have already had at least one cornea transplant.
Jinan, ShandongAges 18–85 - NCT07434518Recruiting
Study of adebrelimab for advanced small cell lung cancer
This study looks at how well adebrelimab works and how safe it is in real-world settings for people with advanced small cell lung cancer that has spread. It may help doctors understand if this treatment is a good option for patients like you.
ShanghaiAges 18–100 - NCT07432711Recruiting
Liposomal bupivacaine for pain after lung surgery
This trial tests if a long-acting numbing medicine called liposomal bupivacaine can reduce pain after video-assisted lung surgery. It aims to help patients feel better after the procedure with less need for other painkillers.
Beijing, Beijing MunicipalityAges 18–64 - NCT07434427RecruitingPhase 4
Buprenorphine vs. oxycodone for pain after lung surgery
This study compares two common pain medicines given through a patient-controlled pump after lung surgery done with small incisions. The goal is to see which one works better and has fewer side effects.
Zabrze, Silesian VoivodeshipAges 18–75 - NCT06295328RecruitingPhase 1/Phase 2
Terbinafine for chronic hepatitis B: safety and effect
This study tests whether a fungus-fighting drug, terbinafine, can help treat chronic hepatitis B. It is for people with stable disease who are not on other antivirals or are only on tenofovir.
Amsterdam, North HollandAges 18–60 - NCT06353334RecruitingPhase 4
Butylphthalide for brain recovery after cardiac arrest
This trial tests if butylphthalide can improve brain function in people who have been resuscitated after a cardiac arrest. It may help reduce brain damage and improve recovery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06345898RecruitingEarly Phase 1
Gene therapy for X-linked retinoschisis in young males
This trial tests a single gene therapy injection under the retina for boys with X-linked retinoschisis, a condition that causes vision loss. It aims to see if the treatment is safe and can improve vision.
Chengdu, SichuanAges 5–18 - NCT06349174Recruiting
Lung valve treatment for severe COPD
This study tests whether placing tiny valves in the airways can help people with severe COPD breathe easier. It is for people who still have trouble breathing despite quitting smoking and completing pulmonary rehab.
Beijing, Beijing MunicipalityAges 40–85 - NCT07423533RecruitingPhase 2
GenSci120 injection for moderate to severe rheumatoid arthritis
This trial tests a new injection called GenSci120 for people with moderate to severe rheumatoid arthritis who haven't improved enough after trying at least one standard arthritis medication. The goal is to see if this treatment can help reduce joint pain and swelling.
Beijing, Beijing MunicipalityAges 18–70 - NCT07419828RecruitingPhase 3
Study of HRS-1780 for chronic kidney disease
This trial tests an investigational drug called HRS-1780 in people with chronic kidney disease. It aims to see if the drug can help slow kidney decline and is safe to use.
Nanjing, JiangsuAges 18–80 - NCT07420816RecruitingPhase 2
Testing a new drug for insomnia
This trial tests a new medication, APSTZD, to see how well it works and how safe it is for people with insomnia, especially those who have trouble staying asleep through the night.
Bragança Paulista, São PauloAges 18–64 - NCT06816771RecruitingPhase 2
Pazopanib plus TGI/CIV for recurrent/refractory rhabdomyosarcoma in children
This trial tests a combination of two drugs (pazopanib and TGI/CIV) for children and teens whose rhabdomyosarcoma has come back or hasn't responded to standard treatment. The goal is to see if this combination can shrink tumors or slow the disease.
Jinan, ShandongAges 2–18 - NCT07423390RecruitingPhase 3
Vitamin B12 to prevent nerve damage from chemo
This trial tests if taking mecobalamin (a form of vitamin B12) can prevent or reduce nerve pain and numbness caused by taxane chemotherapy. It may help people getting chemo for several types of cancer.
Xining, QinghaiAges 18 years+ - NCT07418190RecruitingPhase 2
Combination therapy for relapsed follicular lymphoma
This trial tests a combination of three targeted drugs (zanubrutinib, rituximab, lenalidomide) plus an immunotherapy drug (tislelizumab) for people with follicular lymphoma that has returned or not responded to at least two prior treatments. The goal is to see if this combination is safe and effective.
Nanjing, JiangsuAges 18–75 - NCT07418112RecruitingPhase 4
Laser vs other device for hard bile or pancreas stones
This study compares two types of lithotripsy (stone-breaking) devices, holmium laser and electrohydraulic lithotripsy, for treating difficult stones in the bile or pancreatic ducts. If you have a bile or pancreas stone that is large, stuck, or could not be removed with standard procedures, this trial may help determine which method works best.
Chicago, IllinoisAges 19–85 - NCT07423013Recruiting
Teprotumumab treatment for active thyroid eye disease
This trial tests a new version of an antibody treatment (teprotumumab) for people with active thyroid eye disease. It aims to reduce bulging and inflammation of the eyes, and you must have had symptoms for less than 9 months to join.
BeijingAges 18–80 - NCT06375005RecruitingPhase 2
Telitacicept for early diffuse scleroderma
This trial tests a new drug called telitacicept for people with recently diagnosed, rapidly progressing systemic sclerosis (scleroderma). It aims to see if the drug can slow down skin thickening and other symptoms.
Yangzhou, JiangsuAges 18–70 - NCT06819410Recruiting
Comparing antifungal treatments for invasive fungal disease
This trial studies two types of antifungal medicines (amphotericin B and azoles) to see which works better for people with invasive fungal disease. It aims to help doctors choose the safest and most effective treatment.
Chengdu, SichuanAges Any age - NCT06658145Recruiting
New tool for vaginal hysterectomy for fibroids
This trial tests a new tool that helps doctors see better during vaginal hysterectomy (removing the uterus through the vagina). It is for women with uterine fibroids who need this surgery, and aims to see if it is safe and works well.
Beijing, Beijing MunicipalityAges Up to 60 years
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.