Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07186751Recruiting
Pregabalin and venlafaxine for fibromyalgia pain
This trial tests a combination of two medicines (pregabalin and venlafaxine) for people with fibromyalgia whose pain is moderate to severe and has not been helped enough by non-drug treatments. The goal is to see if the combination works better and is safe.
BeijinAges 18 years+ - NCT07187193RecruitingPhase 2
Low-dose chemo plus thalidomide for untreated LCH
This trial tests a combination of two drugs, low-dose cytarabine and thalidomide, for adults with Langerhans cell histiocytosis (LCH) that has not been treated before with systemic therapy. The goal is to see if this treatment is safe and effective for people with LCH in multiple body areas or multiple spots in one system.
BeijingAges 18–70 - NCT07184801RecruitingPhase 3
Comparing two sedatives for medical thoracoscopy
This trial tests if dexmedetomidate or midazolam is safer and works better for sedation during a medical thoracoscopy, a procedure to look inside the chest. It may help you if you need this procedure for an unclear pleural effusion.
Chandigarh, ChandigarhAges 12–90 - NCT07187206RecruitingPhase 3
Fetoscopic surgery for severe diaphragmatic hernia
This trial tests if a special surgery (FETO) done while the baby is still in the womb can improve survival for babies with a severe form of congenital diaphragmatic hernia (CDH). The surgery places a small balloon in the baby's windpipe to help the lungs grow. We are looking for pregnant women whose baby has a left-sided CDH with a lung-to-head ratio (LHR) less than 30%, or a right-sided CDH with LHR less than 45%, and whose liver is herniated into the chest.
Cincinnati, OhioAges 18–50 - NCT06947707Recruiting
Blood thinners for brain blood clot in Chinese patients
This trial tests two blood thinner medicines, edoxaban and rivaroxaban, in Chinese patients with a blood clot in a brain vein (cerebral venous thrombosis). It aims to see if these medicines are safe and work well.
Beijing, Beijing MunicipalityAges 18–80 - NCT06948357RecruitingPhase 2
Eye drops for presbyopia in Chinese adults
This trial tests two eye drops, BRIMOCHOL PF and CARBACHOL PF, to see if they improve near vision in people with presbyopia (age-related difficulty seeing up close). The study is for Chinese adults aged 45-75 who have trouble reading even with glasses or contacts.
Wenzhou, ZhejiangAges 45–75 - NCT07179159Recruiting
14-day stomach infection treatment study
This study compares two treatments for an H. pylori stomach infection: taking two medicines (vonoprazan and amoxicillin) versus taking four medicines. Both treatments are given for 14 days.
Jinan, ShandongAges 18–70 - NCT07183761RecruitingPhase 2
Stem cell therapy for diabetic nerve pain
This study tests whether umbilical cord stem cells can help people with diabetic nerve damage in their legs who haven't gotten enough relief from standard treatments. It aims to improve symptoms like numbness, pain, and tingling.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT07175519Recruiting
Safety of devices used to treat aneurysms
This study looks at how safe and effective different devices are when used to repair aneurysms through a minimally invasive procedure called endovascular treatment. It may help doctors choose the best treatment for you.
LondonAges Any age - NCT07181135Enrolling by invitationPhase 3
Finerenone for kidney disease without certain blood pressure drugs
This trial tests if finerenone can protect kidneys in people with chronic kidney disease who are not taking common blood pressure medications called ACE inhibitors, ARBs, or renin inhibitors. It may help slow kidney damage.
BarcelonaAges 18 years+ - NCT07178769Recruiting
Testing a supplement for lowering cholesterol
This trial tests a nutritional supplement with bergamot, artichoke, and other natural ingredients to see if it can safely lower cholesterol in people with moderately high LDL. It may be an option for those not currently on other cholesterol treatments.
Madrid, MadridAges 18 years+ - NCT07179055RecruitingPhase 2
A study of VSJ-110 for dry eye disease
This trial tests a new eye drop called VSJ-110 to see if it is safe and effective for treating dry eye, compared to a placebo (inactive drops). It lasts 8 weeks and may help if you have dry eye symptoms.
Newport Beach, CaliforniaAges 18 years+ - NCT07179380RecruitingPhase 3
Inhaled treprostinil for pulmonary hypertension related to interstitial lung disease
This study tests an inhaled powder medication called TPIP (treprostinil palmitil inhalation powder) to see if it can improve symptoms and exercise ability in people who have both interstitial lung disease and pulmonary hypertension. The study will compare TPIP against a placebo (a dummy treatment without the active drug) to understand how well it works and if it is safe.
Phoenix, ArizonaAges 18 years+ - NCT07181837RecruitingPhase 1/Phase 2
Testing MVX-220 for Angelman Syndrome
This study tests an experimental medicine called MVX-220 to see if it is safe and effective for people with Angelman Syndrome. It includes both children (ages 4-8) and adults (ages 18-50) who can walk independently and have stable seizure medications.
Los Angeles, CaliforniaAges 4–50 - NCT07177911RecruitingPhase 1
Study of CC312 for moderate to severe lupus
This trial tests a new medicine called CC312 for people with moderate to severe lupus (SLE) that hasn't improved with standard treatments. The goal is to see if it is safe and can help control the disease.
Chengdu, SichuanAges 18–65 - NCT07177339RecruitingPhase 3
Testing depemokimab for COPD with type 2 inflammation
This study tests an early treatment called depemokimab for people with moderate to severe COPD who have a type of inflammation linked to high eosinophils. It aims to reduce flare-ups and improve breathing.
Newport Beach, CaliforniaAges 40–75 - NCT06752486RecruitingPhase 1
Gabapentin for pain after laser eye surgery
This study tests if a medicine called gabapentin can safely reduce pain after a type of laser eye surgery called surface ablation. It's looking for adults with stable vision who are generally healthy and have not had previous eye procedures.
GizaAges 18–65 - NCT06952413RecruitingPhase 2
Rituximab for chronic fatigue syndrome (ME/CFS) trial
This trial tests if rituximab, a drug that affects the immune system, can help people with ME/CFS. You'll receive the drug in the hospital and be monitored for safety and improvement.
Kodaira, TokyoAges 18–65 - NCT07172347RecruitingPhase 2
VC005 tablets for non-segmental vitiligo
This trial tests an oral tablet called VC005 to see if it can help treat non-segmental vitiligo. It may be an option for adults with vitiligo patches that are not limited to one area of the body.
Beijing, BeijngAges 18–75 - NCT07174115RecruitingPhase 2
Testing a new tablet for chronic sinusitis without nasal polyps
This trial tests an experimental tablet (HTMC0658) for people with chronic sinusitis that hasn't improved with standard nasal spray. You may join if your symptoms are moderate to severe and you've been using a stable dose of mometasone spray for at least 4 weeks.
Luoyang, HenanAges 18–75 - NCT07171099RecruitingPhase 3
Cough medicine for young children with viral colds
This trial tests if a new cough syrup (Rengalin) helps children ages 6 months to 3 years with a dry cough from a viral cold. It aims to reduce cough severity and improve comfort for your child.
GatchinaAges 6 months–3 years - NCT07166263RecruitingEarly Phase 1
Natural killer cell therapy for advanced stomach and colorectal cancer
This trial studies an experimental cell therapy called NK510 for people with advanced stomach or colorectal cancer that has not responded to standard treatments. The therapy uses natural killer cells, a type of immune cell, to attack the cancer. It may help slow or stop the cancer's growth.
Nanjing, JiangsuAges 18 years+ - NCT07168720RecruitingPhase 2
Dexmedetomidine patch for calming children before surgery
This study tests a skin patch that helps children relax before surgery. The patch contains a medicine that is absorbed through the skin to reduce anxiety, so the child may need less anesthesia.
Guangzhou, GuangdongAges 2–6 - NCT07172360RecruitingPhase 3
Study of VC005 tablets for active ankylosing spondylitis
This trial tests a new tablet called VC005 to see if it helps reduce pain and stiffness in people with active ankylosing spondylitis. It's a phase 3 study, meaning it's one of the final steps before the drug may be approved for wider use.
Beijing, Beijing MunicipalityAges 18–70
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.