Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06772168RecruitingPhase 3
New combo pill for diabetes and high cholesterol
This trial tests a new combination pill for people with type 2 diabetes and high cholesterol who are already on metformin. It aims to see if the new drug helps control both blood sugar and cholesterol better than current treatments.
AnyangAges 19–80 - NCT06778447Recruiting
Trial of disc tissue injection for degenerative disc disease
This study tests an experimental treatment that injects donated disc tissue (called an allograft) into damaged discs in your lower back. It's designed for people with chronic low back pain from disc degeneration who haven't found relief from non-surgical treatments.
Napa, CaliforniaAges 22–85 - NCT06776861Recruiting
Radiation plus immunotherapy for advanced breast cancer
This study looks at combining radiation therapy with immunotherapy for advanced breast cancer that has spread or cannot be surgically removed. The goal is to see if adding radiation after treatment helps improve outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06766357RecruitingPhase 3
Cyclosporin gel for moderate to severe dry eye
This study tests a gel form of cyclosporine for people with moderate to severe dry eye that hasn't improved with other treatments. The gel is applied to the eye to help reduce inflammation and increase tear production.
Xiamen, FujianAges 18 years+ - NCT06763965Enrolling by invitationPhase 1/Phase 2
BioTTT001 for recurrent high-grade glioma
This trial tests a new drug called BioTTT001 for people whose high-grade brain tumor has come back after standard treatment. The drug is given through a small device placed in the head to deliver it directly to the tumor area.
Beijing, Chaoyang DistrictAges 18 years+ - NCT06761066Enrolling by invitation
Testing NVP-NK4146 for mild cognitive impairment due to Alzheimer's
This study tests a new medicine, NVP-NK4146, for people with mild cognitive impairment (MCI) due to Alzheimer's disease. The goal is to see if it can help slow down memory and thinking problems.
SeoulAges 60 years+ - NCT06769152RecruitingPhase 2
HLX43 for advanced gynecological cancers
This trial tests a new drug, HLX43, that targets a protein called PD-L1 found on some cancer cells. It is for people with advanced cervical or ovarian cancer that has stopped responding to standard treatments.
Ji'nan, ShandongAges 18–75 - NCT06762431RecruitingPhase 1/Phase 2
CAR T-cell therapy plus lenalidomide for CLL
This trial tests a combination of two treatments—CAR T-cells (your own immune cells reprogrammed to attack cancer) and lenalidomide (a pill that boosts the immune system)—for people with chronic lymphocytic leukemia (CLL) that has not responded to or returned after at least one prior treatment. It aims to see if this combination is safe and works better than either alone.
Vitebsk, Select A StateAges 18 years+ - NCT06290661Recruiting
Nerve stimulation for shingles-related nerve pain
This study tests a treatment called peripheral nerve stimulation (using a small device to send mild electrical pulses) for people with nerve pain after shingles. It's designed for those whose pain is not well managed by usual treatments.
Wuhan, HubeiAges 18 years+ - NCT04699305Recruiting
Test of ActiGraft for draining skin wounds
This trial studies whether ActiGraft helps heal draining (exuding) skin wounds safely and effectively. If you join, the researchers may use your wound photos and health data to analyze results and publish findings.
Las Vegas, NevadaAges 18 years+ - NCT06760169Recruiting
Laser combined with cataract and glaucoma surgery
This study tests a new laser device (ELIOS) during combined cataract and glaucoma surgery. It may help people who need both cataract removal and glaucoma treatment, aiming to lower eye pressure safely.
AvranchesAges 18–80 - NCT06758544RecruitingPhase 1/Phase 2
VRT106 plus chemo for resectable pancreatic cancer
This trial tests a new drug called VRT106 combined with chemotherapy for people with pancreatic cancer that can be surgically removed. The goal is to see if the combination works better than standard treatment alone.
Guangzhou, GuangdongAges 18–75 - NCT06759636RecruitingPhase 3
Comparing two drugs for low platelets from cancer treatment
This trial tests if a new drug called Romiplostim N01 works better than the standard drug Interleukin-11 for raising low platelet counts caused by cancer treatments like chemotherapy or radiation. If you have low platelets from your cancer therapy, you may be able to join.
Nanjing, JiangsuAges 18–75 - NCT05750628RecruitingPhase 2
Testing malaria medicines in uncomplicated falciparum malaria
This trial studies how well and how safely different anti-malaria medicines work for people who have uncomplicated malaria caused by Plasmodium falciparum. You may be eligible if you have a confirmed infection with a certain parasite level and do not have signs of severe disease or major health conditions.
BanforaAges 2–100 - NCT06742996RecruitingPhase 3
Sonrotoclax plus zanubrutinib for relapsed mantle cell lymphoma
This trial tests a new combination of two targeted therapies for people with mantle cell lymphoma that has come back or hasn't responded to prior treatment. It aims to see if adding sonrotoclax to zanubrutinib works better than zanubrutinib alone.
Birmingham, AlabamaAges 18 years+ - NCT06742723RecruitingPhase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure
This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.
Fairhope, AlabamaAges 18 years+ - NCT06739031Recruiting
Testing pulsed electric field ablation for small lung tumors
This trial tests a new treatment that uses short electrical pulses (pulsed electric field ablation) to destroy small lung tumors. It may be an option for people with limited, early-stage non-small cell lung cancer who can tolerate a minimally invasive procedure.
ShanghaiAges 18 years+ - NCT06739720RecruitingPhase 2/Phase 3
Test of CP003 for chronic fatigue or long COVID tiredness
This study tests a new supplement called CP003 to see if it helps reduce tiredness in people with chronic fatigue syndrome or long COVID fatigue.
Hong KongAges 40–60 - NCT06742437Recruiting
Study of a new sperm preparation method
This study tests a new method for preparing sperm to help with fertility treatments. It is for men who can provide a semen sample and have no active infections or history of certain viruses.
Barcelona, BarcelonaAges 18–60 - NCT06735755RecruitingPhase 1/Phase 2
Study of BEAM-301 for glycogen storage disease type Ia
This study tests an experimental medicine called BEAM-301 for people with a specific form of glycogen storage disease type Ia (GSDIa). The goal is to see if it can help reduce dangerous low blood sugar episodes.
Orange, CaliforniaAges 18 years+ - NCT06732648RecruitingPhase 2/Phase 3
Testing a new drug for severe brain swelling after a large stroke
This trial tests a new drug called HRS8179 to reduce severe brain swelling after a large stroke. If you have a major stroke on one side of the brain and can start treatment within 10 hours, this study may help prevent dangerous pressure buildup.
Beijing, Beijing MunicipalityAges 18–80 - NCT06737354Enrolling by invitationPhase 1
Study of IVB103 injection for wet age-related macular degeneration
This trial tests a new treatment called IVB103 for people with wet age-related macular degeneration (AMD). It aims to see if the injection is safe and effective for those who have already had anti-VEGF therapy. You may qualify if you have active disease and have had at least two prior anti-VEGF treatments.
Chengdu, SichuanAges 50 years+ - NCT06736288RecruitingPhase 4
Buccalin® tablets to prevent repeat lung infections
This trial tests whether Buccalin® tablets can help adults who get frequent lower respiratory infections (like bronchitis or COPD flare-ups). It's a phase 4 study collecting more data on safety and how well the medicine works to prevent these infections from coming back.
AlessandriaAges 18–99 - NCT06733246Recruiting
Ceretrieve Device for acute ischemic stroke treatment
This study tests a new device called Ceretrieve that is designed to remove blood clots from large arteries in the brain for people having a severe ischemic stroke. If you are eligible, you will receive the device treatment (a mechanical thrombectomy) within 24 hours of your first symptoms.
HeidelbergAges 18 years+
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.