Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,799 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07035925Recruiting
Testing a hydrogel for treating anal fistulas
This trial tests a hydrogel made from natural materials to help heal a specific type of anal fistula. It may be an option if you have a single high transsphincteric fistula with a seton in place for at least four weeks.
Lebanon, New HampshireAges 18 years+ - NCT07036848Recruiting
Surgery for type IVa bile duct cyst
This study tests how well and safely a surgery works for treating a certain type of bile duct cyst (Todani type IVa). It aims to improve outcomes for people who need this operation for the first time.
Beijing, Beijing MunicipalityAges Up to 80 years - NCT07037199RecruitingPhase 2
A new drug combo for HR+ advanced breast cancer
This trial tests a sequence of three drugs: first trastuzumab rezetecan (a targeted therapy), then a CDK4/6 inhibitor plus hormone therapy. It's for people with a type of breast cancer called HR-positive, HER2-low or ultra-low that has spread or come back and has already progressed on a CDK4/6 inhibitor and hormone therapy.
Guangzhou, GuangdongAges 18 years+ - NCT07037576Recruiting
Breast reconstruction study for patients needing radiation after mastectomy
This study compares two types of breast reconstruction for women who need radiation therapy after their mastectomy: one-stage reconstruction using a permanent implant placed in front of the chest muscle, versus the standard two-stage approach where a tissue expander is used first and replaced with a permanent implant later. The goal is to see which method works better and is safer for patients who require post-mastectomy radiation.
Henan, HenanAges 18–70 - NCT07037862RecruitingPhase 1/Phase 2
Study of ENTR-601-44 for Duchenne muscular dystrophy (exon 44 skipping)
This trial tests a new medicine called ENTR-601-44 for people with Duchenne muscular dystrophy whose genetic mutation can be treated by skipping a part of the gene called exon 44. The goal is to see if it is safe and helps with muscle function.
GhentAges 4–20 - NCT07038824RecruitingPhase 1/Phase 2
A study of ENTR-601-45 for Duchenne MD (exon 45 skipping)
This trial tests an experimental drug called ENTR-601-45 for people with Duchenne muscular dystrophy that can be treated with 'exon 45 skipping.' The goal is to see if it's safe and helps improve muscle function. It's for males between 4 and 20 who can still walk and have enough arm strength.
GhentAges 4–20 - NCT07039396Recruiting
NeoThelium FT for diabetic foot ulcers
This trial tests a new treatment called NeoThelium FT for diabetic foot ulcers. It aims to see if the treatment is safe and helps heal the ulcer. You may join if you have a diabetic foot ulcer that is not infected.
Alexandria, LouisianaAges 18 years+ - NCT07047339RecruitingPhase 2/Phase 3
Probiotic 6600 for colitis patients
This trial tests whether adding Probiotic 6600 to your usual treatment can help manage colitis, including ulcerative colitis or Crohn's disease. It aims to see if the probiotic improves symptoms and is safe to use.
ShanghaiAges 18–75 - NCT07049159RecruitingPhase 2
Testing a new oral vaccine to prevent shigella and ETEC infection
This trial tests an oral vaccine designed to protect against two common causes of severe diarrhea: shigella and ETEC bacteria. Healthy adults aged 18 to 50 will receive the vaccine and later be exposed to the bacteria to see if it works.
Baltimore, MarylandAges 18–50 - NCT07051707Recruiting
Study of a new lung treatment for people with COPD
This trial tests a device called dNerva that targets nerves in the lungs to help people with COPD breathe easier. It is designed for those who have moderate to severe COPD and are not currently smoking.
Birmingham, AlabamaAges 40–80 - NCT07051811Recruiting
Blood vessel treatment for hard-to-control high blood pressure
This trial tests a new device that uses ultrasound to treat nerves in the kidney arteries that may be overactive and raising your blood pressure. It's for people whose blood pressure stays high despite taking at least two medications.
Beijing, Beijing MunicipalityAges 18–75 - NCT07052383RecruitingPhase 1
DIT309 for advanced bone and soft tissue sarcomas
This trial tests a new cell therapy called DIT309 for people with advanced bone or soft tissue sarcoma that hasn't responded to standard treatments. It aims to see if this therapy is safe and effective.
Shanghai, Shanghai MunicipalityAges 8 years+ - NCT07056010Recruiting
Minimally invasive surgery for advanced stomach cancer after chemoimmunotherapy
This trial tests a minimally invasive surgery for stomach cancer that has spread to lymph nodes near the main blood vessels (para-aortic area). The surgery is done after a combination of chemotherapy and immunotherapy to shrink the tumor. It aims to see if this approach is safe and effective.
Nanjing, JiangsuAges 18–80 - NCT07057414RecruitingPhase 2
Testing GMDTC for removing excess cadmium
This trial tests an injectable medicine called GMDTC to help remove extra cadmium (a heavy metal) from the body. It is for people with high cadmium levels and decent kidney function, to see if the drug is safe and effective.
Guangzhou, GuangdongAges 18–70 - NCT07060456RecruitingPhase 3
New drug for type 2 diabetes with insulin
This trial tests a new medicine called HRS9531 for people with type 2 diabetes who already use basal insulin. It aims to see if adding this drug helps control blood sugar better.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07061613Recruiting
Study of NeoThelium FT for venous leg ulcers
This trial tests a new wound dressing called NeoThelium FT for healing venous leg ulcers. It looks at how safe and effective it is.
Metairie, LouisianaAges 18 years+ - NCT07064434Recruiting
Nerve block for safer blood pressure control during hip replacement
This trial tests a type of nerve block (sacral canal block) to help manage blood pressure during hip replacement surgery. It aims to see if it can safely lower blood pressure on purpose, which may reduce bleeding and improve recovery.
Yinchuan, NingxiaAges 45 years+ - NCT07065968RecruitingPhase 2
Teriflunomide and steroids for new immune thrombocytopenia
This trial tests if adding teriflunomide to high-dose dexamethasone helps adults newly diagnosed with immune thrombocytopenia (ITP) who have low platelets or bleeding. It aims to find a safer, more effective way to raise platelet counts.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07068165RecruitingPhase 2/Phase 3
Lenalidomide for active IgG4-related disease
This study tests a drug called lenalidomide to see if it can help control active IgG4-related disease, a condition that causes inflammation and swelling in organs. The drug is taken by mouth, and the study compares it to a placebo (a pill with no medicine).
BeijingAges 18–75 - NCT07068490Recruiting
Potassium blocker study for heart stent patients
This study looks at whether a type of stomach acid medication called PCAB can help people who have had a heart stent and take blood thinners. It checks if PCAB is safe and reduces stomach bleeding.
SeoulAges 18 years+ - NCT07071948Recruiting
Study of VISOR for kidney stone treatment
This trial tests a new device called VISOR to help break up kidney stones using a flexible tube and laser. It's for adults aged 18–80 with stones between 1 and 3 cm who haven't had previous kidney surgery.
Hangzhou, ZhejiangAges 18–80 - NCT07072468RecruitingPhase 2
Test of a gel for nerve pain after chemotherapy
This study tests a new gel (VMD-3866) applied to the skin to treat moderate nerve pain, numbness, or tingling caused by previous chemotherapy. It aims to see if the gel can safely reduce pain for people whose symptoms have been stable for at least 8 weeks.
London, UKAges 18–80 - NCT07073040Recruiting
Cold plasma therapy for diabetic foot ulcers with blocked arteries
This trial tests whether adding cold atmospheric plasma (a gentle gas treatment) to a standard procedure that opens blocked leg arteries can help diabetic foot ulcers heal better and faster.
Anshan, LiaoningAges 18–80 - NCT07075718RecruitingPhase 2/Phase 3
Evaluating a new travoprost eye implant for glaucoma
This trial tests a newer version of a tiny implant placed inside the eye to lower pressure in people with open-angle glaucoma or ocular hypertension. It may offer a treatment option that doesn't require daily eye drops.
Grand Junction, ColoradoAges 18 years+
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,799 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.