Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,799 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06990399RecruitingPhase 3
Testing KSI-101 eye injections for swelling from inflammation
This trial tests a new injected medicine (KSI-101) for people with swelling in the back of the eye caused by inflammation. The medicine is given directly into the eye to see if it can reduce the swelling and improve vision.
Phoenix, ArizonaAges 18 years+ - NCT06994845RecruitingPhase 3
Testing iptacopan for children with IgA nephropathy
This study tests a new medicine called iptacopan to see if it helps children with IgA nephropathy (a kidney disease). Kids who join will receive the study treatment and be monitored for safety and effectiveness.
Aurora, ColoradoAges 2–18 - NCT06996080RecruitingPhase 3
Study of KSI-101 for swelling caused by eye inflammation
This trial tests a new medicine called KSI-101 given as an injection into the eye to treat swelling in the center of the retina caused by inflammation. It may help people whose vision has gotten worse due to this type of swelling.
Phoenix, ArizonaAges 18 years+ - NCT06998745Recruiting
Anticoagulant therapy support for colorectal cancer patients with blood clots
This trial tests whether a medication therapy management (MTM) model helps make blood thinner treatment safer and more effective for colorectal cancer patients who have also developed dangerous blood clots. It aims to improve how well patients stick to their medication and reduce complications.
Guangzhou, GuangdongAges 18–100 - NCT07000383Recruiting
Gelsectan for diarrhea-predominant IBS
This trial tests if Gelsectan, a dietary supplement, can safely reduce diarrhea and abdominal pain in people with diarrhea-predominant irritable bowel syndrome (IBS-D). It may be a new option for managing your symptoms.
Ho Chi Minh City, District 5Ages 18 years+ - NCT07001540RecruitingPhase 2
Targeted drug combo for relapsed DLBCL
This trial tests a combination of targeted antibody drugs (polatuzumab vedotin and rituximab) plus two chemo drugs (gemcitabine and oxaliplatin) for people with DLBCL whose cancer returned after their first treatment and who cannot have a stem cell transplant. The goal is to see if this combination works better as a second-line treatment.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07002034RecruitingPhase 2
RE104 for adjustment disorder related to cancer or other serious illnesses
This trial is testing a new medication (RE104) for people who have adjustment disorder with depressed mood or anxiety because of a serious medical condition like cancer, ALS, MS, Parkinson's, or lung fibrosis. It's a study to see if the drug is safe and reduces symptoms.
Birmingham, AlabamaAges 18–80 - NCT07007962RecruitingPhase 3
Oral pill for immune thrombocytopenia after first treatment fails
This trial tests an oral medicine called rilzabrutinib for adults with immune thrombocytopenia (ITP) whose first treatment stopped working or who need steroids long-term. The goal is to see if it helps raise platelet counts and reduce bleeding risk.
Clovis, CaliforniaAges 18 years+ - NCT07008456RecruitingPhase 2
Testing a new sugar-bead treatment for weight loss in obesity
This study tests a new treatment—small beads of sugar that release in the lower intestine—to help people with obesity and related health conditions lose weight. It compares two different doses of the beads plus a gel to a placebo (inactive treatment).
Tbilisi, K'alak'i T'bilisiAges 18–75 - NCT07009067Recruiting
Exercise after surgery for aortic dissection: a safety study
This study tests whether a supervised exercise program is safe and helpful for people who have had surgery for a type of aortic tear (type B aortic dissection). It aims to see if exercise can improve recovery without causing complications.
Guangzhou, GuangdongAges 18–75 - NCT07009171RecruitingPhase 2
Testing KDS2010 for weight loss in overweight or obese adults
This study tests a new medication called KDS2010 for people who are overweight or have obesity. The goal is to see if it helps with weight loss when combined with diet and exercise.
Suwon, Gyeonggi-doAges 18 years+ - NCT07009236Recruiting
MINIject S+ for open angle glaucoma
This trial tests a tiny implant called MINIject S+ to lower eye pressure in people with open angle glaucoma that isn't well controlled with eye drops. It may be done alone or with cataract surgery.
Santa Rosa de CopánAges 20 years+ - NCT07012304RecruitingPhase 1/Phase 2
Testing gecacitinib for chronic graft-versus-host disease after 2 or more treatments
This trial tests a new drug, gecacitinib, for patients with moderate to severe chronic graft-versus-host disease (cGVHD) that has not improved after 2 to 5 prior treatments. It aims to see if the drug is safe and effective.
BeijingAges 18 years+ - NCT07013201RecruitingPhase 2
Testing a new cream for palmoplantar pustulosis
This trial tests a cream called delgocitinib for people with mild to severe palmoplantar pustulosis (PPP), a skin condition with pustules on the palms and soles. The cream is applied daily for 16 weeks to see if it improves symptoms and is safe.
Fountain Valley, CaliforniaAges 18 years+ - NCT07014163Recruiting
Testing Embella injection for lipomas
This trial tests a new injection called Embella (deoxycholic acid) to treat small, stable lipomas (fatty lumps) on your trunk, arms, or legs. The goal is to see if it safely shrinks the lumps without needing surgery.
Tehran, Tehran ProvinceAges 18–65 - NCT07015242RecruitingPhase 2
Liso-cel for newly treated primary CNS lymphoma
This trial tests a new cancer immunotherapy called liso-cel (a CAR T-cell treatment) as a first treatment for people with primary CNS lymphoma who cannot have a stem cell transplant. If you've already received some high-dose methotrexate and your tumor responded, this study may offer a more targeted therapy to try to improve results.
Aurora, ColoradoAges 18 years+ - NCT07017634RecruitingPhase 3
Novosis Putty for spine fusion in lumbar disc disease
This trial tests a new bone graft putty (Novosis Putty) used during a specific type of spine fusion surgery (TLIF) to treat a worn-out disc causing low back and leg pain. The goal is to see if it works as well as or better than current options.
Baton Rouge, LouisianaAges 21–80 - NCT07017725RecruitingPhase 1/Phase 2
Testing a new drug for chronic low platelets
This trial tests an investigational drug called CID-103 for adults with chronic immune thrombocytopenia (ITP), a condition where the immune system destroys platelets. It aims to find the right dose and see if it can safely increase platelet counts to reduce bleeding risk.
Tangshan, HebeiAges 18–65 - NCT07018648Recruiting
Testing a wearable heart monitor for rhythm problems
This trial tests a chest belt that works with your smartphone to track heart rhythms. It may help if you have or might have an irregular heartbeat.
Olomouc, CzechiaAges 18 years+ - NCT07021508Recruiting
Testing a new brain stimulation for bipolar depression
This trial tests a new type of brain stimulation called temporal interference stimulation to see if it can safely and effectively improve symptoms of bipolar depression. It may be an option for people who are not taking medication or who are willing to stop their current medication for a short time.
Hangzhou, ZhejiangAges 18–45 - NCT07022197RecruitingPhase 1/Phase 2
BAFF-R CAR T cells for severe nerve and immune diseases
This trial tests a new treatment using your own immune cells (called BAFF-R CAR T cells) for people with severe nerve and immune diseases that have not improved with standard medicines. These cells are designed to target and destroy certain immune cells that may be causing your illness.
Tianjin, Tianjin MunicipalityAges 18–60 - NCT07023614RecruitingPhase 2
Study of Ninerafaxstat for Non-Obstructive Hypertrophic Cardiomyopathy
This trial tests an investigational drug (ninerafaxstat) for people with a specific type of thickened heart muscle called non-obstructive hypertrophic cardiomyopathy. The goal is to see if the drug can improve symptoms and exercise ability.
La Jolla, CaliforniaAges 18 years+ - NCT07027072RecruitingPhase 2
Testing KDS2010 for early Alzheimer's memory loss
This study tests a new drug called KDS2010 for people with early Alzheimer's or mild memory loss. It aims to see if the drug can slow thinking and memory decline. You will need a caregiver to help with visits and must have a special brain scan showing amyloid plaques.
Gwangju, GwangjuAges 50–85 - NCT07030907RecruitingPhase 1
Testing OPB-101 for platinum-resistant ovarian cancer
This trial tests a new treatment called OPB-101 for people with a type of ovarian, peritoneal, or fallopian tube cancer that has stopped responding to platinum chemotherapy. The goal is to see if it is safe and if it can help shrink or slow the cancer.
Detroit, MichiganAges 18 years+
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,799 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.