Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06646354Enrolling by invitationPhase 3
Study of two experimental drugs for high blood pressure and cholesterol
This trial tests whether taking two experimental drugs together can safely lower both high blood pressure and high cholesterol. It may be an option if you have both conditions and your blood pressure is not extremely high.
SeoulAges 19 years+ - NCT06650319RecruitingEarly Phase 1
Testing LY-M003 injection for Wilson disease
This study tests an injection called LY-M003 for people with Wilson disease who have already been treated with standard medicines. The goal is to see if it is safe and works for them.
Hangzhou, ZhejiangAges 10–60 - NCT06643130RecruitingPhase 3
Testing a combo treatment for high blood pressure and cholesterol
This study tests whether adding two medications together helps people who have both high blood pressure and high cholesterol. It aims to see if the combination works better and is safe.
SeoulAges 19 years+ - NCT06639828RecruitingPhase 4
Safety study of Sonazoid for liver ultrasound in children
This trial tests a contrast agent called Sonazoid, which is used during an ultrasound to get clearer pictures of the liver. It is for children and teens who have one or more spots in the liver that need to be checked. The goal is to see if Sonazoid is safe and works well for children.
MünchenAges Up to 18 years - NCT06643819RecruitingPhase 3
Testing a new blood pressure drug
This trial tests a new combination blood pressure medicine called CKD-202A. It is for adults with high blood pressure who have not had other treatments or conditions that could affect the results.
WŏnjuAges 19 years+ - NCT06640998Enrolling by invitation
Matrix pro for eyebrow and neck lift
This trial tests a radiofrequency microneedling device called Matrix Pro to lift droopy eyebrows and tighten loose skin under the chin and neck. It may help if you have mild to moderate skin laxity and are willing to avoid other cosmetic treatments during the study.
Marlborough, MassachusettsAges 18–75 - NCT06637254Enrolling by invitationPhase 2
Testing an oral tablet for hard-to-control asthma
This study tests an oral tablet (HSK31858) to see if it helps control asthma in people whose asthma is not well managed with current inhalers. It focuses on those with a specific type of asthma where certain blood cells are low.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06639256RecruitingPhase 1/Phase 2
Testing a new drug for advanced solid tumors
This trial is testing a new drug called HY07121 for people with advanced solid tumors that have not responded to standard treatments. The goal is to see if the drug is safe and effective.
JinanAges 18–80 - NCT06638710RecruitingPhase 2
Testing oral midazolam for care in elderly with dementia who refuse care
This trial tests if giving a medication called midazolam by mouth can help older adults with memory problems who refuse care to accept it more calmly. It is for people in certain hospital or long-term care units, with moderate to severe memory loss and a history of resisting care.
Grenoble, IsereAges 60 years+ - NCT06620809RecruitingPhase 1
New treatment for neuromyelitis optica flare-ups
This trial tests a new medicine (NouvSoma001) for people with neuromyelitis optica (NMOSD) who are having a flare-up. The goal is to see if the treatment is safe and if it helps reduce symptoms like pain and trouble moving.
Wuhan, HubeiAges 18–65 - NCT06620328Recruiting
Comparing two tools for bile duct drainage when ERCP fails
This study tests two ways of opening a blocked bile duct when standard methods fail: one using a special balloon and the other using heat. It looks at which is safer and works better for people who cannot get the usual ERCP or PTCD drainage.
TaipeiAges 18 years+ - NCT06625970RecruitingPhase 3
Darolutamide and high-dose radiation for high-risk prostate cancer
This trial tests a combination of a hormone therapy pill (darolutamide) and a high-dose, precise form of radiation for men with localized prostate cancer that has high-risk features of coming back. The goal is to see if this approach is more effective than standard treatment.
BrestAges 18–80 - NCT06630091RecruitingPhase 2
Golidocitinib for newly diagnosed peripheral T-cell lymphoma
This study tests a new pill called golidocitinib for people newly diagnosed with certain types of peripheral T-cell lymphoma who have not been treated before. The goal is to see if it is safe and effective in shrinking or controlling the lymphoma.
Houston, TexasAges 18 years+ - NCT06630806RecruitingPhase 1
Study of an injection for relapsed or refractory myeloma
This trial tests a new injected drug for people with multiple myeloma that has returned or stopped responding to at least 3 prior treatments. The goal is to see if the drug is safe and works against the cancer.
Phoenix, ArizonaAges 18 years+ - NCT06625385Recruiting
Testing a new vacuum dressing for wound healing
This trial tests a new vacuum dressing (3M V.A.C. Peel and Place) to see how safe and well it works for different types of wounds. The dressing helps wounds heal by gently pulling fluid and dirt out, and this study wants to make sure it works well for you.
Indianapolis, IndianaAges 22 years+ - NCT06631989RecruitingPhase 1/Phase 2
Study of WSD0922-FU for advanced EGFR-mutant lung cancer
This trial tests a new drug called WSD0922-FU for people with advanced non-small cell lung cancer that has a specific EGFR gene change. It aims to see if the drug can help when previous EGFR treatments have stopped working.
Hefei, AnhuiAges 18–75 - NCT06628908RecruitingPhase 3
Study of suzetrigine for painful diabetic nerve damage
This trial tests an experimental medicine called suzetrigine to see if it can safely reduce pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It might be an option if you have had daily pain in both legs and current treatments haven't worked well enough.
Anniston, AlabamaAges 18–80 - NCT06619860RecruitingPhase 2
VX-993 for diabetic nerve pain
This trial tests a new medicine called VX-993 for people with diabetes who have had nerve pain in both feet or legs for at least a year. The goal is to see if it reduces pain and is safe.
Cullman, AlabamaAges 18–80 - NCT06627699Recruiting
Study of the Freedom Total Knee System for knee replacement
This study is for people getting a total knee replacement for the first time. It looks at how well the Freedom Total Knee System works in everyday life.
Leawood, KansasAges 18 years+ - NCT06204991RecruitingPhase 1
T-cell therapy for advanced melanoma
This trial tests a new treatment called ADP-TILIL7 for people with advanced melanoma. It uses your own immune cells (T-cells) that are taken from a tumor, multiplied in a lab, and then given back to you to fight the cancer. The goal is to see if this treatment is safe and works better than standard options.
HerlevAges 18–75 - NCT05695261RecruitingPhase 2
Oral microbiome capsules for peanut allergy in teens
This Phase 2 study tests whether taking capsules made from donor gut microbes is safe and can reduce allergic reactions to peanuts. It involves peanut allergy testing and close follow-up with stool samples and check-ins.
Boston, MassachusettsAges 12–17 - NCT06615479RecruitingPhase 3
New treatment vs standard care for relapsed multiple myeloma
This trial tests a new treatment called BMS-986393 (a type of CAR T-cell therapy) compared to standard treatments for adults with multiple myeloma that has come back or is not responding to therapy, and who have already been treated with lenalidomide (Revlimid). The goal is to see if the new treatment works better.
Birmingham, AlabamaAges 18 years+ - NCT06616727Enrolling by invitationPhase 1
CAR-T cell therapy for recurrent glioblastoma
This trial tests a new CAR-T cell treatment (SNC-109) for people with glioblastoma that has come back after initial treatment. The therapy uses your own immune cells, modified in a lab, to try to attack the tumor.
BeijingAges 18 years+ - NCT06607627RecruitingPhase 3
Testing gefurulimab in children with generalized myasthenia gravis
This study tests a new drug called gefurulimab in children and teens with generalized myasthenia gravis (a disease that causes muscle weakness). It looks at how safe and effective the drug is, and how it works in the body.
Washington D.C., District of ColumbiaAges 6–17
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.