Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,799 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07133308RecruitingPhase 3
Study of deuruxolitinib for teens with severe alopecia areata
This study tests an investigational oral medication (deuruxolitinib) for adolescents with severe alopecia areata (hair loss). It aims to see if it can help hair regrow safely.
Birmingham, AlabamaAges 12–17 - NCT07138755RecruitingPhase 2
PD-1, chemo, and adaptive radiation for stage 3 lung cancer
This study tests if adding an immunotherapy drug (PD-1 inhibitor) to chemotherapy and specially planned radiation works better for stage 3 lung cancer that cannot be surgically removed. It may be an option if you have not had previous treatment for this cancer.
Changsha, HunanAges 18–75 - NCT07140328RecruitingPhase 2
Testing a new inhaler for COPD symptoms
This trial tests two forms of a new medication (HSK39004) in people with COPD. The goal is to see if they help improve breathing and are safe. Eligible participants must be between 40 and 80, have moderate to severe COPD, and be able to stop other COPD treatments during the study.
Nanchang, JiangsuAges 40–80 - NCT07140523RecruitingPhase 2
Testing a new blood thinner for knee replacement surgery
This study tests a new injection called SRSD107 to see if it prevents blood clots after knee replacement surgery, compared to a standard blood thinner (enoxaparin). It might be an option if you are having a planned knee replacement and are otherwise healthy.
Nové Město na MoravěAges 60–80 - NCT07140913RecruitingPhase 3
Testing KarXT for bipolar I mania with mood stabilizers
This study tests whether adding KarXT to lithium, valproate, or lamotrigine helps calm manic episodes in people with bipolar I disorder. It aims to see if the combination is safe and works better than the mood stabilizer alone.
Bentonville, ArkansasAges 18–65 - NCT07145229RecruitingPhase 2
Testing a new drug for acute gout flares
This trial tests a new medication, ABP-745, for people having an acute gout flare. It aims to see if the drug is safe and helps reduce pain and inflammation.
Peoria, ArizonaAges 18–70 - NCT07146022RecruitingPhase 3
Study of VDPHL01 for women with hair thinning
This trial tests whether a new oral treatment, VDPHL01, can help women with mild to moderate pattern hair loss. It also checks for side effects and how the drug works in the body.
Birmingham, AlabamaAges 18–65 - NCT07149857RecruitingPhase 2
A study of CAR-T therapy for newly diagnosed multiple myeloma
This trial tests a one-time cell therapy called ciltacabtagene autoleucel (a CAR-T treatment) in people who have newly diagnosed multiple myeloma and are not eligible for a stem cell transplant. It aims to see if this treatment is safe and effective as an early therapy.
San Francisco, CaliforniaAges 18–80 - NCT07150000Recruiting
Rheumatic disease research study for patients and healthy volunteers
This study is for people with certain rheumatic conditions (like arthritis, lupus, or vasculitis) and for healthy volunteers. It aims to learn more about these diseases and improve how they are treated.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT07150013RecruitingPhase 1
Vorinostat for Rett syndrome safety study
This trial tests whether vorinostat is safe and helpful for girls and young women with Rett syndrome. Participants must have a confirmed MeCP2 mutation and be in a stable phase of the condition.
MedellínAges 6–21 - NCT07150052Recruiting
Testing an AI tool for carb counting in type 1 diabetes
This study tests an AI-powered tool (called Tiabete) that helps you count carbohydrates more easily. If you have type 1 diabetes and use insulin, the tool may help you manage your blood sugar better.
São Paulo, São PauloAges 6 years+ - NCT07150975RecruitingPhase 3
Study comparing new weekly injection vs. Wegovy for weight loss
This trial tests a new weekly injection called GZR18 against the existing drug Wegovy for weight loss in adults who are overweight or obese. It aims to see which is more effective and safe for helping people lose weight and improve related health conditions.
BeijingAges 18 years+ - NCT07152392RecruitingPhase 4
Testing IBI311 for inactive thyroid eye disease symptoms
This trial tests a medication called IBI311 for people with inactive thyroid eye disease that still causes bothersome symptoms like double vision or trouble closing the eyes. The goal is to see if it helps improve these problems safely.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07152366RecruitingPhase 4
Hormone and tetuzumab for active thyroid eye disease
This trial tests a new sequence of hormone therapy followed by a targeted drug (tetuzumab) for people with moderate to severe thyroid eye disease that is still active after steroid treatment didn't help enough.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07152340RecruitingPhase 4
Sequential hormone and IBI311 therapy for active TAO
This trial tests a two-step treatment for active, moderate-to-severe thyroid eye disease (TAO). You will first receive hormone therapy, followed by a drug called IBI311. The goal is to see if this sequence works better for people who have not had steroid treatment before.
Changhua, Shanghai MunicipalityAges 18–80 - NCT07152639RecruitingPhase 3
New skin test for tuberculosis in people 3 and older
This trial tests a new skin test (EEC) to see if it can accurately detect tuberculosis infection in people aged 3 and older. It compares the test's results in healthy people, people with TB, and people with other lung diseases to check how well it works.
Beijing, Beijing MunicipalityAges 3 years+ - NCT07156175RecruitingPhase 2
Study of new treatment for microscopic colitis in remission
This study tests whether a new medication (SAR444336) can help adults with microscopic colitis stay in remission longer. It may be an option if you are already taking budesonide and have had flares in the past 8 months.
GhentAges 18 years+ - NCT07156773RecruitingPhase 2
Nasal spray for Parkinson's off episodes
This study tests a new nasal spray called XJN010 for people with Parkinson's who have 'off' episodes—times when their regular medication wears off and symptoms come back. The goal is to see if the spray can safely and effectively help during those periods.
Guangzhou, GuangdongAges 30–85 - NCT07157033RecruitingPhase 1/Phase 2
Testing XER-001 with radiation for advanced pancreatic cancer
This trial tests a new way to deliver a drug called amifostine (XER-001) alongside intense radiation therapy (SBRT) for people with locally advanced pancreatic cancer that can't be surgically removed. The goal is to see if it's safe and effective at protecting healthy tissue while targeting the tumor.
Duarte, CaliforniaAges 18 years+ - NCT07157254RecruitingPhase 2
Study of GTX-102 for People with Angelman Syndrome
This study tests an experimental drug called GTX-102 for people with Angelman syndrome. It aims to see if the drug is safe and can help with symptoms. The trial includes different age groups and genetic types of Angelman syndrome.
Los Angeles, CaliforniaAges 1–64 - NCT07157631Recruiting
Tranexamic acid for adults having liver transplant
This trial tests if tranexamic acid, a medicine that helps blood clot, can safely reduce bleeding during adult liver transplant surgery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07157852Recruiting
Testing pregabalin vs mirogabalin for fibromyalgia pain
This study tests two medications, pregabalin and mirogabalin, for people with fibromyalgia who have not yet tried prescription drugs. It aims to see which one works better for pain relief.
BeijingAges 18 years+ - NCT07158658Recruiting
Study of a new skin graft for pressure sores
This trial tests a new skin graft called NeoThelium FT for stage 2 or 3 pressure ulcers on the pelvis or lower leg. It’s for adults whose wounds are not infected and who can use a wound vacuum to help healing.
Bossier City, LouisianaAges 18 years+ - NCT07158775RecruitingPhase 1/Phase 2
BS01 gene therapy for dry age-related macular degeneration
This trial tests a new gene therapy, BS01, given as an eye injection. It is for people with advanced dry age-related macular degeneration (AMD) that has caused geographic atrophy—damage to the central part of the retina. The study aims to see if the treatment is safe and can help slow vision loss.
Edison, New JerseyAges 50–85
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,799 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.