Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,799 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07269782RecruitingPhase 2
Pre-surgery treatment for stage II-III lung cancer
This study tests two investigational drugs (HLX43 and serplulimab) given before surgery to people with stage II to III non-small cell lung cancer (NSCLC). The goal is to see if these drugs can shrink the tumor and make it easier to remove completely during surgery.
ShanghaiAges 18–75 - NCT07270003Recruiting
Ivarmacitinib for palmoplantar pustulosis
This trial tests a new oral medication, ivarmacitinib, for adults with palmoplantar pustulosis (PPP) who haven't gotten better with standard treatments. It aims to see if the drug is safe and effective for reducing the painful pustules on the palms and soles.
Xi'an, ShaanxiAges 18 years+ - NCT07270705Recruiting
OROXID® mouth rinse for gum disease
This trial tests an oral rinse called OROXID® for people with gingivitis (gum disease). It looks at whether the rinse helps reduce gum bleeding and swelling. You may join if you are generally healthy, have at least 20 natural teeth, and have mild gum inflammation but not severe gum disease.
LjubljanaAges 18 years+ - NCT07271225Recruiting
Ear acupuncture for nausea from TB drugs
This study tests whether ear acupuncture can help reduce nausea and vomiting caused by tuberculosis medications. It is for people who are at least 17 years old, have drug-sensitive or certain types of drug-resistant TB, and feel sick after taking their TB pills.
Jakarta, Jakarta TimurAges 17 years+ - NCT07273721RecruitingPhase 2
Testing BT200 in type 2B von Willebrand disease
This trial tests a new medicine called BT200 (rondaptivon pegol) to see if it can safely help people with type 2B von Willebrand disease who have low platelets and recent bleeding problems.
Vienna, State of ViennaAges 18 years+ - NCT07276581RecruitingPhase 2
Testing AZD1163 for active rheumatoid arthritis
This study tests a new medication called AZD1163 for people with rheumatoid arthritis (RA) that hasn't responded well enough to standard treatments. It aims to see if the drug can safely reduce joint swelling and pain.
Glendale, ArizonaAges 18 years+ - NCT07276789RecruitingPhase 2
Single-dose dye imaging for lung cancer surgery
This trial tests a single dose of a special dye (LS301-IT) that helps surgeons see lung cancer cells more clearly during surgery. It aims to make lung cancer removal more precise and complete.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07279194RecruitingPhase 3
Study of HDM1005 for weight loss in Chinese adults without diabetes
This trial tests a new medication, HDM1005, to help people with obesity or overweight who do not have diabetes lose weight. It is for Chinese adults who have a high body mass index (BMI) or a BMI above 24 with weight-related health problems like high blood pressure or fatty liver.
ShanghaiAges 18 years+ - NCT07279493RecruitingPhase 2
Testing KPCXM18 injection for acute ischemic stroke within 12 hours
This trial tests an investigational injection called KPCXM18 for people having an acute ischemic stroke. It is given within 12 hours of symptom onset, in addition to standard clot-dissolving treatment, to see if it improves recovery and safety.
Beijing, Beijing MunicipalityAges 18–80 - NCT07282028RecruitingPhase 2/Phase 3
Spectacle hearing aid study for adults with mild to moderate hearing loss
This study tests a new hearing aid built into glasses for people who have mild to moderate hearing trouble, especially in noisy places. It aims to see if the glasses help you hear better without needing a traditional hearing aid.
Tel AvivAges 18 years+ - NCT07282743RecruitingPhase 2
Study of GL0034 for overweight or obese adults with type 2 diabetes
This trial tests a new medication, GL0034, to see if it helps with weight loss and blood sugar control in people with type 2 diabetes who are overweight. Participants must already be taking metformin and not using other diabetes drugs.
Little Rock, ArkansasAges 18 years+ - NCT07285460RecruitingPhase 3
Fitusiran for young boys with hemophilia A or B
This trial tests if fitusiran, given as a shot, can help prevent bleeding in boys ages 1 to 12 with severe hemophilia (factor VIII under 1% or factor IX at 2% or lower). It includes boys with or without inhibitors and aims to understand safety and how well it works.
Los Angeles, CaliforniaAges 1–11 - NCT07285590RecruitingPhase 2
Testing pirtobrutinib and rituximab for mantle cell lymphoma
This trial tests a new drug combination (pirtobrutinib plus rituximab) for people with mantle cell lymphoma who have not yet received any treatment and do not have symptoms. The goal is to see if the combination is safe and effective.
Lisbon, Lisbon DistrictAges 18 years+ - NCT07285629RecruitingEarly Phase 1
Klotho and follistatin gene therapy safety study
This trial tests a one-time gene therapy that may help slow or reverse signs of aging. It is for healthy adults aged 50 to 80 who are open to possible visible body changes.
Austin, TexasAges 50–80 - NCT07285941RecruitingPhase 2
New targeted drug plus chemo for advanced ovarian cancer
This study tests whether a new targeted drug (distamab vedotin) combined with standard chemo (carboplatin) works better than chemo alone for women with advanced ovarian cancer that has high levels of HER2. It is for women who have not had chemotherapy yet and have already had surgery to remove the tumor.
Zhejiang, ZhejiangAges Any age - NCT07286214RecruitingPhase 4
Study of sarilumab for early polymyalgia rheumatica
This trial tests whether the drug sarilumab can help people with newly diagnosed or early relapsing polymyalgia rheumatica (PMR) reduce their need for prednisone. It aims to see if the combination is safer and more effective than prednisone alone.
Denver, ColoradoAges 50 years+ - NCT07286747RecruitingPhase 2
Nicotinic Acid for Reversing Prediabetes
This trial tests whether a controlled-release form of nicotinic acid (a type of vitamin B3) can help people with prediabetes get their blood sugar back to normal. It also looks at how the treatment affects liver health.
KielAges 18–79 - NCT07287943Recruiting
Medtronic pump study for diabetes and gastroparesis
This study tests whether the Medtronic 780G insulin pump helps people with type 1 diabetes and gastroparesis (slowed stomach emptying) control their blood sugar better than their usual care. It requires continuous glucose monitoring and certain blood sugar levels.
Indianapolis, IndianaAges 18 years+ - NCT07290010RecruitingPhase 2
Iparomlimab plus chemotherapy for advanced esophageal cancer
This trial tests a combination of two immunotherapy drugs (Iparomlimab and Tuvonralimab) with chemotherapy as a first treatment for advanced esophageal squamous cell carcinoma. It aims to see if this combination is safe and effective for people whose cancer cannot be removed by surgery or has spread.
Shijiazhuang, HebeiAges 18 years+ - NCT07292168RecruitingPhase 1/Phase 2
Study of a new antibody for advanced tumors with FGFR1 protein
This trial tests an experimental antibody, OM-RCA-01, in people with advanced solid tumors that have high levels of a protein called FGFR1. It aims to see if the drug is safe and effective for those who have already tried other treatments.
Kazan'Ages 18 years+ - NCT07295275Recruiting
Fluorescence-guided surgery for liver cancer
This trial tests a new way to remove liver cancer during surgery. A special dye called ICG is injected into the artery leading to the liver, which makes the tumor glow under a special camera, helping the surgeon remove just the right area. This study checks if this technique is both safe and effective for people with a common type of liver cancer (hepatocellular carcinoma).
Beijing, Beijing MunicipalityAges 18–80 - NCT07297329RecruitingPhase 3
Newly diagnosed multiple myeloma trial for transplant-ineligible patients
This trial tests a new drug called SCTC21C combined with standard treatments (bortezomib, lenalidomide, and dexamethasone) for people newly diagnosed with multiple myeloma who cannot have a stem cell transplant. The goal is to see if this combination is safe and works better than current options.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07297602RecruitingPhase 2
Oral roflumilast for moderate to severe eczema in teens and adults
This study tests an oral medicine called roflumilast to see if it helps treat moderate to severe eczema in people aged 12 and up who haven't used other systemic treatments recently. It's a pilot study to check both safety and how well it works.
Al Mansurah, Dakahlia GovernorateAges 12 years+ - NCT07301749Recruiting
Study of VCFix device for spine fractures
This trial tests a new device called VCFix to treat a single broken vertebra in the mid-to-lower back. It aims to see if the device is safe and effective for relieving pain and restoring spine function.
ChambéryAges 21–85
Hear when a new Efficacy and Safety trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,799 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.