Clinical trials
Endometrial Cancer clinical trials
Below are recruiting endometrial cancer clinical trials, each written for real people, not researchers. We’re tracking 297 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07610798RecruitingPhase 1/Phase 2
Testing INV-8989 for Advanced Cancers With KRAS G12D Mutation
This early-stage trial tests a new drug called INV-8989 designed to target a specific genetic mutation (KRAS G12D) found in some advanced solid cancers. The study will evaluate whether the drug is safe and if it can help shrink tumors in patients who haven't responded to standard treatments.
Guangzhou, GuangdongAges 18 years+ - NCT07593820RecruitingPhase 1
CAR-T Cell Study for Advanced HER2-Positive Cancers
This early-stage trial tests a new type of immune cell therapy called CAR-T cells, which are designed to recognize and attack cancer cells that have a protein called HER2. The cells are made from your own immune cells, trained in the laboratory, and given back to you. The study evaluates how safe the treatment is and whether it can shrink tumors.
Barcelona, CataloniaAges 18 years+ - NCT04590326RecruitingPhase 1/Phase 2
Study of REGN5668 with or without immunotherapy in ovarian cancer
This Phase 1/2 study tests how safe REGN5668 is and how well it works in adult women with advanced gynecologic cancers. It compares REGN5668 given with cemiplimab alone, or cemiplimab plus fianlimab, and looks for responses in tumors that meet specific criteria.
Duarte, CaliforniaAges 18 years+ - NCT02012699Recruiting
Cancer registry for people with or at risk of cancer
This trial collects health information and samples (a “cancer repository”) to help researchers study cancer and cancer risk. You may be able to join if you’ve had cancer before or if you’re at higher risk or have concerning findings.
Greenwood Village, ColoradoAges 19–110 - NCT04774419RecruitingPhase 2
Radiation plus dostarlimab for post-surgery endometrial cancer
This Phase 2 study tests whether adding dostarlimab (an immunotherapy medicine) to radiation after surgery can lower cancer returning and improve outcomes. It’s for people with certain endometrial cancers found to have specific genetic/molecular changes and who have stage III/IVA disease after surgery.
Basking Ridge, New JerseyAges 18 years+ - NCT06680791Recruiting
Endometrial cancer study on recurrence prevention and lifestyle
This study looks at how your cancer type and daily habits might help prevent endometrial cancer from coming back. It only requires that you've had endometrial cancer and a hysterectomy.
PragueAges Any age - NCT06995833Recruiting
Durvalumab with or without Olaparib for endometrial cancer
This trial collects safety information on the standard use of Durvalumab (with or without Olaparib) in people with endometrial cancer in Korea. It helps doctors confirm the real-world effects of these approved treatments.
SeoulAges Any age - NCT06952504RecruitingPhase 3
Comparing two drug combos for advanced endometrial cancer
This trial tests a new drug combination (sacituzumab tirumotecan plus pembrolizumab) against pembrolizumab alone for people with a specific type of advanced or recurrent endometrial cancer that has normal mismatch repair function. It aims to see which treatment works better.
Mobile, AlabamaAges 18 years+ - NCT05255653RecruitingPhase 3
Adjuvant treatment for high-risk endometrial cancer based on tumor genetics
This trial tests whether adding an immunotherapy drug called durvalumab to the usual treatment can improve outcomes for people with a specific genetic type of endometrial cancer that is at high risk of returning. It is designed for people who have already had surgery to remove the cancer.
AntwerpAges 18 years+ - NCT05049538Recruiting
Liquid blood tests to predict endometrial cancer return
This trial studies whether blood “liquid biopsies” and tumor genetic testing can help predict whether endometrial cancer will come back after treatment. Results may help doctors plan follow-up and additional care based on a person’s recurrence risk.
Houston, TexasAges 18 years+ - NCT06515613RecruitingPhase 1
Testing CTIM-76 for recurrent ovarian and other advanced cancers
This trial tests a new drug, CTIM-76, in people whose ovarian, testicular, or endometrial cancer has come back and is not responding to standard treatments. It aims to see if the drug can shrink tumors or stop them from growing.
Little Rock, ArkansasAges 18 years+ - NCT05990426Recruiting
Alternate day fasting during chemo for gynecologic cancers
This trial tests whether alternating between a fasting day and a normal eating day can help people recovering from gynecologic cancer surgery while they receive chemotherapy. It aims to see if this eating pattern is safe and helpful during treatment.
Chicago, IllinoisAges 18 years+ - NCT07584161Recruiting
Radiation therapy comparison after cervical or endometrial cancer surgery
This trial compares two types of radiation therapy (a newer technique called MH-ART versus a standard technique called CF-IMRT) given after surgery for cervical or endometrial cancer. The goal is to see which approach works better and causes fewer side effects.
Beijing, Beijing MunicipalityAges 18–75 - NCT07316361Enrolling by invitationEarly Phase 1
Personalized vaccine for high-risk endometrial cancer
This trial tests a personalized vaccine made from your tumor's unique proteins to help your immune system fight high-risk or advanced endometrial cancer. It is given along with your regular cancer treatments.
Thessaloniki, ThessalonikiAges Any age - NCT07109726RecruitingPhase 1/Phase 2
Testing TER-2013 for advanced tumors with AKT/PI3K/PTEN changes
This trial tests a new drug called TER-2013, alone or combined with another drug (fulvestrant), for people with advanced solid tumors that have specific genetic changes in the AKT/PI3K/PTEN pathway. It aims to see if the drug is safe and effective.
Duarte, CaliforniaAges 18 years+ - NCT07048327Recruiting
Study of uterine disease diagnosis
This study observes patients who need a scope exam or scraping of the uterus to look for conditions like polyps, fibroids, or cancer. It aims to gather information to improve care.
Wuhan, HubeiAges 18–80 - NCT06795009RecruitingPhase 1
Zanzalintinib plus paclitaxel for recurrent uterine cancer
This trial combines an experimental pill called zanzalintinib with a standard chemotherapy (paclitaxel) for people with advanced or recurrent high-grade uterine cancer who have already tried platinum-based chemotherapy. The goal is to see if this combination can help shrink or control the cancer better than standard options alone.
San Francisco, CaliforniaAges 18 years+ - NCT06834204Enrolling by invitation
Better care coordination for cancer survivors
This study tests a program to improve communication between your cancer team and your regular doctor. If you have heart or diabetes risks and you're being treated for breast, prostate, bladder, or endometrial cancer, this trial may help coordinate your care.
New Brunswick, New JerseyAges 18 years+ - NCT07371663RecruitingPhase 1/Phase 2
TCC1727 combination therapy for advanced solid tumors
This trial tests a new drug, TCC1727, combined with other treatments for people with advanced solid tumors that have stopped responding to standard therapy. It aims to see if these combinations can help shrink or control the cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05579366RecruitingPhase 1/Phase 2
Study of rinatabart sesutecan for advanced solid tumors
This trial tests an investigational drug called rinatabart sesutecan (also known as Rina-S) for people with advanced solid tumors, including ovarian, endometrial, lung, breast, and other cancers. The drug is designed to target and kill cancer cells, and the study aims to see if it is safe and effective.
Phoenix, ArizonaAges 18 years+ - NCT05559879RecruitingPhase 1/Phase 2
Cabozantinib and dostarlimab for recurrent gynecologic carcinosarcoma
This trial tests the combination of cabozantinib and dostarlimab to treat recurrent (coming back) gynecologic carcinosarcoma, after standard chemotherapy has already been tried. It aims to shrink tumors and improve outcomes by targeting cancer pathways.
Birmingham, AlabamaAges 18 years+ - NCT05857631Recruiting
After-surgery radiation schedule for cervical or uterine cancers
This trial studies a shorter, focused radiation schedule given after surgery for certain higher-risk cervical or endometrial (uterine) cancers. It may help reduce cancer recurrence while checking side effects in the bladder and bowel area.
Navi Mumbai, MaharahstraAges 18–80 - NCT05123482RecruitingPhase 1/Phase 2
Study of an experimental drug for advanced solid tumors
This trial tests a new drug, called AZD8205, alone or with other medicines, for people with advanced or metastatic solid tumors that have not responded to standard treatment. It aims to see if the drug can shrink tumors or slow their growth.
Duarte, CaliforniaAges 18 years+ - NCT04504006Recruiting
Tracking surgery choices for lymph node spread in endometrial cancer
This is an observational study that follows people with endometrial cancer who have had surgery to check and remove pelvic (and sometimes paraaortic) lymph nodes. It looks at how different surgical approaches and any added treatment affect local control (keeping cancer from coming back in the pelvis/nearby areas).
Essen, North Rhine-WestphaliaAges 18 years+
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Common questions
- Are there clinical trials for endometrial cancer?
- Yes. Clin2 currently lists 297 recruiting endometrial cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a endometrial cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a endometrial cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.