Clinical trials
Endometrial clinical trials
Below are recruiting endometrial clinical trials, each written for real people, not researchers. We’re tracking 364 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05231122RecruitingPhase 2
Pembrolizumab and bevacizumab for recurrent ovarian cancer
This trial studies whether adding pembrolizumab to bevacizumab (and sometimes an anti-CD40 drug) can help control recurrent ovarian, fallopian tube, or primary peritoneal cancer. It also looks at whether the treatment can shrink tumors and keep them from growing for longer.
Buffalo, New YorkAges 18 years+ - NCT05349227Recruiting
After-cancer digital coaching and wearable tracking outcomes study
This study tests a digital health coaching program (using phone/tablet check-ins and wearable data) to understand health and quality-of-life outcomes after cancer treatment. It may help you learn healthy habits and track progress over time.
Gainesville, FloridaAges 18 years+ - NCT05366881Recruiting
Blood test study to spot early cancer signal and cancer leftovers
This observational study checks whether a blood test (a “cfDNA” test) can detect early signs of cancer or small amounts of cancer left after treatment. It may help doctors use a simple blood sample to improve cancer detection and follow-up.
Duarte, CaliforniaAges 40 years+ - NCT05410717RecruitingPhase 1
CAR-NK cell therapy for certain solid tumors
This early-phase trial tests a lab-made immune cell treatment for advanced solid tumors that show specific targets (including Claudin 6, GPC3, Mesothelin, or AXL). It may help the immune system better recognize and kill tumor cells, but eligibility depends on test results and your overall health.
Guangzhou, GuangdongAges 18–75 - NCT05421364Recruiting
Boosting your own immune cells to improve the uterine lining
This study gives a small amount of your own immune cells into the uterus to change the immune environment in the uterine lining. It aims to improve how the uterine lining supports implantation, especially for people trying to conceive with embryo transfer of normal (euploid) embryos.
Sofia, SofiaAges 20–50 - NCT05463796Recruiting
Prevention and early detection for people at high cancer risk
This study looks at surveillance (watching closely), prevention, and early “interception” steps to lower the chance that cancer will develop or be found later. It is for people with genetic risk, past cancer treatment exposures, strong family history, or certain early pre-cancer or high-risk conditions.
Boston, MassachusettsAges Any age - NCT05489211RecruitingPhase 2
Testing a cancer drug for advanced solid tumors
This Phase 2 study tests the drug Dato-DXd (alone or with other cancer medicines) in people with advanced solid tumors. It looks for tumor shrinkage and how safely the treatment can be given.
Los Angeles, CaliforniaAges 18–130 - NCT05559879RecruitingPhase 1/Phase 2
Cabozantinib and dostarlimab for recurrent gynecologic carcinosarcoma
This trial tests the combination of cabozantinib and dostarlimab to treat recurrent (coming back) gynecologic carcinosarcoma, after standard chemotherapy has already been tried. It aims to shrink tumors and improve outcomes by targeting cancer pathways.
Birmingham, AlabamaAges 18 years+ - NCT05579366RecruitingPhase 1/Phase 2
Study drug for advanced ovarian and other solid cancers
This Phase 1/2 trial studies Rinatabart Sesutecan to treat advanced cancers, with special focus on certain ovarian cancer types. It’s meant for people whose cancer has come back or has not responded to prior treatments.
Phoenix, ArizonaAges 18 years+ - NCT05610501Recruiting
Ultrasound-guided biopsy for pelvic masses
This study looks at how well an ultrasound-guided needle biopsy (Tru-Cut) can safely collect tissue samples from pelvic masses. It may help doctors confirm diagnoses and guide treatment by improving how biopsies are done in real-world care.
LeuvenAges 18 years+ - NCT05635123Recruiting
Study of newly diagnosed cervical or endometrial cancer
This study follows women who are newly diagnosed with cervical or endometrial (uterine lining) cancer at a health check-up. It helps doctors learn more about these cancers and how they behave, which may improve future care.
Hangzhou, ZhejiangAges 20–75 - NCT05669430RecruitingPhase 1/Phase 2
Testing an anti-cancer drug alone and with pembrolizumab
This early-phase study tests GV20-0251 (an anti-cancer treatment) by itself and combined with pembrolizumab, to see how well it works and how safe it is. It is for adults with advanced solid tumors that have grown despite standard treatments, or where standard treatments aren’t an option.
Los Angeles, CaliforniaAges 18 years+ - NCT05743517Recruiting
Exercise program for older women with gynecologic cancer
This trial tests a physical activity (exercise) program for women over 60 who are being treated for cancers of the uterus, ovaries, cervix, or vulva/vagina. It may help improve strength and daily functioning during treatment.
Chicago, IllinoisAges 60 years+ - NCT05758688RecruitingPhase 2
Proton radiation after surgery for uterine or cervical cancer
This trial studies whether proton beam radiation after surgery can better treat certain uterine (endometrial) or cervix (cervical) cancers. It may help by targeting the pelvic area while limiting radiation to nearby organs.
Voorhees Township, New JerseyAges 18 years+ - NCT05770102RecruitingPhase 2/Phase 3
Atezolizumab for cancers with high mutation or immune markers
This trial tests atezolizumab, a cancer immunotherapy, for people whose tumors have high mutation levels (TMB), or are “MSI-high,” or have CMMRD. It may help shrink cancer or slow its growth by boosting the immune system’s ability to recognize the tumor.
BelfastAges Any age - NCT05793749Recruiting
Prevent leg swelling after gynecologic cancer treatment
This study tests an early approach to help prevent lower-limb lymphedema (chronic leg swelling) after lymph node surgery and radiotherapy for gynecologic cancer. If you’re at risk, it may help your legs stay less swollen and reduce complications.
Chongqing, Chongqing MunicipalityAges 18–60 - NCT05833321Recruiting
Testing a way to detect low muscle in women with certain cancers
This study looks at whether doctors can spot “low muscle” (sarcopenia) in everyday clinic care for people with ovarian or endometrial cancer who are planning to start chemotherapy. It may help your care team identify muscle loss early and potentially support better treatment planning.
Chambéry, SavoieAges 18 years+ - NCT05855941Recruiting
Imaging tests to better predict and diagnose gynecologic cancers
This trial studies how well medical imaging (especially MRI) can help predict outcomes and improve diagnosis in people newly diagnosed with certain gynecologic cancers. It may help doctors make more accurate treatment decisions by comparing imaging results to the final cancer type and stage.
UmeåAges 18 years+ - NCT05856981RecruitingPhase 1
Testing ADU-1805 for advanced solid tumors safety
This early study tests whether ADU-1805 is safe in people with advanced solid tumors and checks how the body processes the drug. Depending on your cancer type, it may also be looking specifically at certain cancers that have not yet received PD-(L)1 immunotherapy.
Detroit, MichiganAges 18 years+ - NCT05856838Recruiting
Endometrial ablation for heavy periods when medicines don’t work
This study looks at an outpatient procedure that removes part of the uterine lining to reduce very heavy menstrual bleeding. It may help you if birth control or medicines haven’t worked (or you can’t take them) and your uterus tests come back normal.
Ghent, East FlandersAges 35–50 - NCT05862805RecruitingPhase 1/Phase 2
Testing treatments affecting uterine bleeding during periods
This early-stage study tests medicines that may help control heavy uterine bleeding by changing how blood clots work in the uterus. If you have regular periods and meet the setup rules, you may be asked to provide menstrual tracking and undergo an endometrial (uterine lining) biopsy.
Portland, OregonAges 18–45 - NCT05867251RecruitingPhase 1/Phase 2
AVZO-021 for advanced breast and ovarian cancers
This early-stage study tests AVZO-021, a new anti-cancer medicine, in people with advanced solid tumors like specific types of breast and ovarian (or related) cancers. It’s meant to find the safest dose and look for signs the medicine can shrink tumors, especially in cancers with certain gene changes.
New Haven, ConnecticutAges 18 years+ - NCT05912972Recruiting
Registry study for women with gynecologic cancers
This is a research study that builds a registry (a record) of women in Korea with cervical, endometrial, or ovarian cancer. It may help researchers better understand these cancers and plan future studies.
SeoulAges 18 years+ - NCT05914974Recruiting
Tracking inflammation changes during immunotherapy in gynecologic cancer
This trial looks at how a blood inflammation marker (CRP) changes when people with metastatic gynecologic cancers receive immunotherapy, sometimes together with palliative chemotherapy. The goal is to see patterns that may help doctors better understand and manage treatment responses to immunotherapy.
TübingenAges 18 years+
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Common questions
- Are there clinical trials for endometrial?
- Yes. Clin2 currently lists 364 recruiting endometrial studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a endometrial trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a endometrial trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.