Clinical trials
Esophagectomy clinical trials
Below are recruiting esophagectomy clinical trials, each written for real people, not researchers. We’re tracking 40 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05706558Recruiting
Study of esophageal cancer surgery records
This study looks back at past patients’ medical and pathology records from esophageal cancer surgeries. It may help improve how doctors understand which advanced tumors should be treated, by reviewing outcomes in specific tumor stages.
New York, New YorkAges 18 years+ - NCT05865743RecruitingPhase 3
Antibiotic cloth before surgery to prevent esophagus infection
This Phase 3 trial tests whether using an antibiotic decolonization treatment around the time of esophagus surgery can reduce serious infections afterward. It may help you lower the risk of postoperative infectious complications after curative esophagectomy or esophagus reconstruction.
LeuvenAges 18 years+ - NCT05877300RecruitingPhase 1
Test a new esophagus implant to rebuild a short esophagus segment
This Phase 1 study tests the safety and feasibility of a new esophagus implant for people who need only a short (about 6 cm or less) section of their esophagus rebuilt after serious injury or scarring. If it does not work, you must be willing to have a planned “rescue” surgery later.
Los Angeles, CaliforniaAges 18 years+ - NCT05906134RecruitingPhase 1/Phase 2
Pain control plan after minimally invasive esophagus surgery
This trial tests a pain-control method (using an epidural/nerve pain-block through the back, called neuraxial anesthesia) for people having minimally invasive esophagus removal surgery. It may help reduce pain after surgery and improve comfort during recovery.
Seattle, WashingtonAges 18 years+ - NCT06067438RecruitingPhase 2
Amiodarone to Prevent Irregular Heartbeat After Esophageal Cancer Surgery
This trial tests if amiodarone, a medication that helps keep your heart rhythm steady, can prevent a type of irregular heartbeat called atrial fibrillation after surgery to remove part of your esophagus. If you are having this surgery (called minimally invasive esophagectomy or MIE) for cancer or other esophagus problems, you may be able to join.
Portland, OregonAges 18 years+ - NCT06136845Recruiting
Esophageal cancer microbiome and leak after surgery
This study looks at bacteria in esophageal cancer tumors and whether certain bacteria are linked to leaks that can happen after surgery to remove the esophagus. It may help doctors understand how to prevent these leaks in the future.
HaifaAges 18–85 - NCT06576973RecruitingPhase 2
Adalimumab combo therapy for esophageal cancer before surgery
This trial tests a combination of an immunotherapy drug (adalimumab), chemotherapy, and a targeted therapy pill (apatinib) before surgery for esophageal cancer that can be removed. The goal is to see if this mix helps shrink the tumor and improve outcomes.
Hangzhou, ChinaAges 18–75 - NCT06897501Recruiting
Comparing breathing tubes for voice box protection during esophagectomy
This trial compares two types of breathing tubes used during robot-assisted esophageal cancer surgery. One tube blocks one lung (double-lumen tube) and the other tube uses a smaller blocker (bronchial blocker); researchers want to see which causes fewer voice box nerve injuries after surgery.
SeoulAges 19 years+ - NCT07004634Recruiting
Comparing Drain Types After Minimally Invasive Esophageal Cancer Surgery
This study compares two different ways of placing drains after minimally invasive surgery for esophageal cancer. It aims to find which method helps you recover better and with fewer complications.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07043491Recruiting
Comparing scopes and X-rays after esophagus surgery
This trial compares two ways doctors check the surgical connection (anastomosis) after removing a cancerous part of the esophagus. It looks at whether a flexible tube with a camera (endoscopy) or a special X-ray (esophagram) is better for routine follow-up.
Guangzhou, GuangdongAges 18 years+ - NCT07187154Recruiting
Symptom management after esophagus cancer surgery
This trial tests a symptom management program using a WeChat mini program for people recovering from esophagus cancer surgery. It aims to help you track and manage your symptoms based on your own reports after the operation.
BeijingAges 18 years+ - NCT07317609RecruitingPhase 1
Immunotherapy plus chemo before endoscopic resection for esophageal cancer
This trial tests a treatment plan that combines immunotherapy with chemotherapy before possible endoscopic surgery. It is for people with a specific type of esophageal cancer that has not been treated before and is either potentially removable or not suitable for standard surgery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT02530983Recruiting
Survey study for people after esophagus surgery
This study is a survey. It asks people about their experiences after esophagus surgery (either removing part of the esophagus or rebuilding it). It may help doctors understand what happens to patients over time and improve future care.
Rochester, MinnesotaAges 18 years+ - NCT02634645Recruiting
Treatment study for Barrett’s pre-cancer or esophageal cancer
This study looks at treatment options for people with Barrett’s esophagus that has progressed to abnormal cell growth (dysplasia) or cancer. It may help doctors compare approaches that use procedures to remove and/or destroy abnormal tissue in the esophagus.
Los Angeles, CaliforniaAges 18–100 - NCT07519486RecruitingPhase 2
Nutrition support during cancer treatment before surgery
This trial tests whether intensive nutritional support helps patients with advanced esophageal cancer (a type of squamous cell carcinoma) respond better to treatment before surgery. The goal is to improve how well the cancer shrinks and prepare the body for a successful operation.
Chengdu, SichuanAges 18–80 - NCT07567716Enrolling by invitation
Study of How Advanced Esophageal Cancer Spreads After Surgery
This research examines tissue samples from patients who had surgery to remove advanced esophageal cancer in the neck or chest area. The study aims to understand how the cancer invaded surrounding tissues, which may help doctors better treat similar patients in the future.
ShanghaiAges Any age
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Common questions
- Are there clinical trials for esophagectomy?
- Yes. Clin2 currently lists 40 recruiting esophagectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a esophagectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a esophagectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.