Clinical trials
Extremity Injury clinical trials
Below are recruiting extremity injury clinical trials, each written for real people, not researchers. We’re tracking 50 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05267951Recruiting
Closed-loop spinal stimulation to improve hand use after spinal injury
This trial tests a smart form of spinal stimulation that responds to your body’s signals to help improve upper-extremity (arm/hand) function after a spinal cord injury. If it works, it may make everyday hand tasks like dressing, grooming, or feeding easier.
Seattle, WashingtonAges 21–70 - NCT06489106Enrolling by invitation
Spinal stimulation to improve hand function in kids with spinal cord injury
This study tests a noninvasive spinal stimulation device to help children with spinal cord injury regain hand strength and control. It may improve grip and daily activities.
Louisville, KentuckyAges 7–12 - NCT06903962Recruiting
Mind-body program for chronic arm or hand pain
This trial tests whether a mind-body program can help people with long-term pain in their upper arm, forearm, or hand that is not caused by a clear physical injury. It focuses on retraining how your brain responds to pain triggers.
Boston, MassachusettsAges 18–60 - NCT07402655Recruiting
Study on nerve injuries in the arm and their long-term effects
This study looks at people who have had a recent nerve injury in their arm, hand, or wrist that needed treatment. It aims to understand how the injury affects movement, feeling, and quality of life over time.
IspartaAges 18–80 - NCT04545502Recruiting
Study of aortic grafts and heart patches after aortic surgery
This study looks at how well certain aortic grafts and cardiovascular patches work after surgery. It may help by improving care for people who need these devices, and by collecting safety and outcome information over time.
Aurora, ColoradoAges 18 years+ - NCT05780502Recruiting
Orthotic and rehab program for lower-limb musculoskeletal problems
This study tests an integrated brace (an exoskeletal orthosis) plus a rehabilitation plan for problems in the legs/lower limbs. It may help improve how you move and function while using a custom brace.
Charlotte, North CarolinaAges 18 years+ - NCT04789044RecruitingPhase 2
PEG treatment to improve nerve repair after upper-arm injury
This Phase 2 study tests a PEG-based approach meant to help damaged peripheral nerves heal and regain movement and feeling after an upper-arm/hand nerve injury. You may be screened quickly after injury to see if the nerve pattern and your health situation fit the study plan.
Baltimore, MarylandAges 18–80 - NCT00623389Recruiting
Testing a leg neuroprosthesis for walking and leg control
This trial tests an advanced device that helps control and use your legs and trunk muscles for movement. It may help people with certain types of paralysis or weakness to improve function, while closely monitoring safety and comfort.
Cleveland, OhioAges 21–75 - NCT06616025RecruitingPhase 3
Study of NTX-001 for nerve repair in arm injuries
This trial tests a surgical glue-like product (NTX-001) to help mend cut nerves in the arm or hand. If successful, it could improve recovery of movement and feeling after nerve injury.
Los Angeles, CaliforniaAges 18–80 - NCT01459107RecruitingPhase 2
Upper arm transplant study using immune treatment
This trial tests replacing a missing or non-working lower arm/hand with a donated upper limb (transplant). It also uses a special immune treatment plan and bone marrow infusion to help the body accept the new limb, aiming to improve hand function and quality of life.
Baltimore, MarylandAges 18–69 - NCT06903416RecruitingPhase 2/Phase 3
Nerve stimulation for arm and hand function after spinal cord injury
This study tests a non-invasive, painless nerve stimulation technique to see if it can improve arm and hand function after a spinal cord injury. It may help people who have had a neck-level injury more than 9 months ago.
Edmonton, AlbertaAges 18–75 - NCT07303582RecruitingPhase 4
Freezing nerves to ease pain from muscle tightness
This study tests if freezing specific nerves (cryoneurolysis) can reduce pain caused by muscle tightness (spasticity) after a brain or spinal cord injury, or from multiple sclerosis. It is for people who already get Botox injections for this pain.
OxfordAges 18 years+ - NCT07432685Enrolling by invitation
Can movement predict chronic pain after combat limb injuries?
This study is looking for people with combat-related arm or leg injuries to see if how they move can predict long-term pain. Researchers hope to better understand who might develop chronic pain and help improve treatment.
LvivAges 18–50 - NCT06153121Recruiting
Arm and shoulder tests for healthy tennis players and swimmers
This study is for healthy tennis players and swimmers. It tests a set of physical performance tests for the upper body (arms, shoulders, hands) to see how well they measure athletic ability. If you are a competitive tennis player or swimmer and have no arm or shoulder problems, you may be eligible.
GhentAges 12–40 - NCT03400345Recruiting
Follow-up for transplanted arm patients
This study follows people who received a transplanted arm (or both arms) to learn from their ongoing care. You may be asked for small tissue samples (biopsies) and to continue an immunotherapy plan to help protect the transplant.
Baltimore, MarylandAges 18–100 - NCT03610763Recruiting
Training brain recovery after arm nerve repair
This study tests a way to help your brain and nerves work better after an arm/hand nerve repair that is already in the long-term (chronic) recovery stage. It may help improve hand and arm function by targeting “neuroplasticity,” meaning the brain’s ability to adapt after injury.
Louisville, KentuckyAges 18 years+ - NCT06743607Recruiting
Spinal stimulation to improve arm and hand function at home
This trial tests whether using a special device that sends small electrical currents to the spinal cord can help people recovering from a recent spinal cord injury regain movement in their arms and hands. The treatment happens in your home with the help of a caregiver.
Englewood, ColoradoAges 18 years+ - NCT07241572Recruiting
Heart injury risk during below-knee surgery
This trial checks for heart muscle injury during surgery on the lower leg (below the knee). It helps doctors understand how to better protect patients having this type of operation.
AnkaraAges 18 years+ - NCT05191121Enrolling by invitation
Rehab program to improve arm and trunk control after spinal injury
This trial helps people with recent traumatic spinal cord injury improve arm movement and trunk (upper body) stability using a training program that includes electrical stimulation. If you’re early after injury and can safely use stimulation, you may benefit from more controlled movement for daily tasks.
Englewood, ColoradoAges 18 years+ - NCT05243966Recruiting
Registry for soft tissue repair using a special matrix
This study is a registry that collects information from people who had soft tissue repair using a specific matrix and/or morcell material. It may help researchers understand how this approach performs in real-world care and patient outcomes over time.
Phoenix, ArizonaAges 18 years+ - NCT06156904Recruiting
Study of b.Bone bone graft for defects in arms, legs, pelvis
This trial is following patients who receive a bone graft using a product called b.Bone to treat bone defects in the arms, legs, or pelvis. Researchers will collect information during your regular follow-up visits to see how well the bone heals.
BerlinAges 18 years+ - NCT05699174RecruitingPhase 3
Compare two antibiotic routes for infected broken bones after surgery
This Phase 3 trial tests whether giving antibiotics by mouth (PO) works as well as giving antibiotics through a vein (IV) for an infected fracture that has not healed after prior surgery. It may help you understand which approach is safer and more effective for getting the bone to heal.
Indianapolis, IndianaAges 18 years+ - NCT06065384Recruiting
Arm training for recovery after recent spinal cord injury
This trial tests a type of arm and hand exercise training to see if it helps the brain and nerves recover after a recent spinal cord injury in the neck. It may help people who have some movement left in their arms or hands.
AntwerpAges 16–90 - NCT05521958Enrolling by invitation
Gene activity study in severe leg muscle swelling after fracture
This study looks at gene activity (what genes are “turned on or off”) in the lower leg in people with acute compartment syndrome after a tibia (shin bone) injury. The goal is to better understand what is happening in the body and potentially guide future treatment decisions.
Salt Lake City, UtahAges 18–90
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Common questions
- Are there clinical trials for extremity injury?
- Yes. Clin2 currently lists 50 recruiting extremity injury studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a extremity injury trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a extremity injury trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.