Clinical trials
Femoropopliteal Artery Disease clinical trials
Below are recruiting femoropopliteal artery disease clinical trials, each written for real people, not researchers. We’re tracking 23 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05307263Recruiting
Atherectomy plus drug balloon versus drug balloon alone
This study compares two ways to treat complex blockages in the thigh/knee artery: using atherectomy followed by a medicated balloon versus using a medicated balloon by itself. It may help your care team learn which approach works best to open the artery and improve leg symptoms.
SeoulAges 19–85 - NCT03791970Recruiting
Compare stent post-dilation using drug balloon or regular balloon
This study looks at whether using a drug-coated balloon (DCB) versus a regular balloon (POBA) right after placing a stent works better in artery blockages in the thigh/knee area. It may help improve blood flow and reduce the chance the artery narrows again.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT04511234Recruiting
Sirolimus-coated balloon vs standard balloon for leg artery narrowing
This trial compares two balloon treatments used during a procedure to open blocked or narrowed arteries in the thigh and behind the knee. It tests whether the sirolimus-coated balloon works better at keeping the artery open than a standard balloon.
SingaporeAges 21 years+ - NCT04584632Recruiting
Stent-like device for blocked leg arteries in the thigh or knee
This trial studies a new stent-like vascular scaffold to improve blood flow in people with symptomatic blockage in the thigh/knee artery. It may help reduce symptoms from narrowed or blocked arteries, but you must meet several artery and health requirements.
Sydney, New South WalesAges Any age - NCT05780359Recruiting
Testing a drug-coated stent for leg artery blockages
This study tests whether a special “drug-eluting” stent placed in a leg artery works safely and improves blood flow for people with peripheral artery disease. It may help reduce re-narrowing and improve walking, depending on your blockage details and overall health.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05894863Recruiting
Smart stent for severe leg artery blockages
This trial studies a new “smart” stent placed in the thigh-to-knee artery to treat significant blockages. It may help improve blood flow to the foot, and you would be followed closely to see how well the stent works over time.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06082466Recruiting
Comparing two types of leg bypass surgery
This study compares two types of bypass surgery for blocked leg arteries. One uses a standard vein from your own body, and the other uses a vein supported by a special metal frame. The goal is to see which works better and lasts longer.
SalzburgAges 18 years+ - NCT06539689Recruiting
Sperstent for remaining blockages after balloon treatment in leg arteries
This trial tests a special stent called Sperstent for people who still have blockages or tears in their leg arteries after balloon treatment. It is designed to help improve blood flow and reduce symptoms like leg pain or sores.
Beijing, Beijing MunicipalityAges 18–85 - NCT07122167Recruiting
Study of a drug-coated stent for blocked leg arteries
This study is testing a new drug-coated stent for blocked arteries in the thigh or behind the knee. It may help people with moderate to severe leg pain or wounds by improving blood flow without needing surgery.
Chrzanów, ChrzanowAges 18–80 - NCT07353905Recruiting
Ultrasound guidance for leg artery treatment
This trial tests whether using a special ultrasound probe inside the artery (intravascular ultrasound) helps doctors better treat blocked leg arteries. It may lead to more effective procedures for patients with leg pain or wounds due to poor blood flow.
Dallas, TexasAges 18 years+ - NCT07431437Enrolling by invitation
GENOSS paclitaxel balloon for leg artery disease
This trial tests a special balloon coated with paclitaxel (a drug that helps keep arteries open) in people with narrowed or blocked leg arteries. It aims to see how well the balloon works over one year.
SeoulAges 19–85 - NCT07399080Enrolling by invitation
Study of a drug-coated balloon for leg artery disease
This trial is testing a special balloon coated with a drug (paclitaxel) to treat narrowed or blocked arteries in the leg. It aims to see how well this balloon works to keep the artery open.
SeoulAges 19–85 - NCT07397390Enrolling by invitation
Study of a new scoring balloon for leg artery blockages with heavy calcium buildup
This study tests a new balloon device that scores the artery walls to treat leg artery blockages with heavy calcium deposits. It aims to see if the device helps prepare the vessel safely and effectively before placing a stent.
Dalian, LiaoningAges 18–85 - NCT06260488Recruiting
Using AI to study leg arteries before amputation
This trial uses artificial intelligence to analyze CT scans and microscope images of the main leg artery. It aims to improve understanding of artery structure. Participation is only for patients who are already scheduled for a leg amputation as part of their medical care.
Strasbourg, Bas-RhinAges 18 years+ - NCT05517291Recruiting
Compare two stent types for blocked thigh artery disease
This trial compares a special drug-coated balloon/stent strategy versus a standard stent approach for people with blocked thigh artery segments. It aims to improve how long the artery stays open and reduces repeat procedures.
BeijingAges 18–85 - NCT06315023Enrolling by invitation
A registry study for the DETOUR system
This study is collecting information from people who receive the DETOUR system, a treatment for blocked arteries. The goal is to see how well it works in real-world use.
Salinas, CaliforniaAges Any age - NCT05522218Recruiting
Eluvia stent for blocked or narrowed leg artery
This trial looks at using an Eluvia drug-coated stent to treat a blocked or severely narrowed artery in the upper leg/knee area. It may help improve blood flow to the leg, and the study will follow patients to see how they do over time.
Hangzhou, ZhejiangAges Any age - NCT06112171Recruiting
Comparing treatments for leg artery blockages with severe calcium
This trial tests a special preparation method (breaking up calcium) plus a Supera stent versus standard preparation plus stenting for people with severe calcium buildup and long blockages in the thigh or behind-the-knee artery. It aims to see which approach works better for opening the artery and keeping it open.
Leipzig, SaxonyAges 18 years+ - NCT06713850Recruiting
Balloon treatment for leg artery blockages with calcium
This trial uses a special balloon (Shockwave IVL) to break up calcium in leg artery blockages, improving blood flow and reducing pain. It's for people with moderate to severe calcium buildup in the femoropopliteal artery.
Wuhan, HubeiAges 18 years+ - NCT07427108Recruiting
Road map vs. ultrasound for retrograde leg angioplasty
This trial compares two imaging methods (road map vs. ultrasound) to guide a needle puncture from the ankle area during angioplasty for blocked leg arteries. It aims to see which method is safer and more effective for patients with severe leg wounds or ulcers that need this retrograde approach.
SohagAges 18 years+ - NCT07282301Recruiting
Filter to catch debris during leg artery cleaning
This trial tests a special filter that catches debris during a procedure to clear blockages in the leg artery (the one behind the knee). It aims to reduce the risk of debris traveling to smaller blood vessels, which can cause complications. If you have a hardened leg artery and plan to have plaque removal before a stent or balloon, this study may be for you.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07052435Recruiting
Measuring pressure and flow during leg artery treatment
This study looks at how well blood flows through leg arteries after using a balloon to open blockages. It uses special measurements to check if the treatment fully restores blood flow, which may help guide future treatments.
PátraiAges Any age - NCT04743180Recruiting
Registry of a drug balloon for leg artery blockages
This study follows people with blocked blood vessels in the thigh and behind the knee to see how well a drug-coated balloon (“Luminor”) works over 5 years. It’s designed to collect real-world results and track safety and outcomes long term.
Bordeaux, New AquitaineAges 18 years+
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Common questions
- Are there clinical trials for femoropopliteal artery disease?
- Yes. Clin2 currently lists 23 recruiting femoropopliteal artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a femoropopliteal artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a femoropopliteal artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.