Fracture Fixation, Internal clinical trials

Open Reduction and Internal Fixation of Humeral Midshaft Fracture: Anterior Versus Posterior Plate Fixation

Heel bone fusion for severe fractures

This trial tests whether fusing the joint just below the ankle (subtalar joint) during heel bone fracture repair helps people with severe fractures heal better. You may qualify if you have a specific type of broken heel bone and can return for follow-up visits for one year.

Surgery comparison for unstable pelvic and hip socket fractures

This study looks at how to best surgically fix unstable pelvic and acetabular (hip socket) fractures, comparing different operative approaches. You might benefit if your goal is stable healing with a less invasive internal fixation method, but the study requires specific fracture types and long follow-up time.

Robot-assisted surgery for thigh bone fractures

This trial tests whether a robot can help doctors fix a broken thigh bone (femur) near the knee. It may lead to more precise surgery and potentially better recovery.

Robot-assisted surgery for hip fracture repair

This study tests whether using a robot to help fix a broken hip (specifically a type of fracture called intertrochanteric) leads to better recovery. The robot assists the surgeon in placing a metal nail inside the bone to hold it together while it heals.

Hip screws or hip replacement for small hip fractures

This study compares two treatments for certain small, stable hip fractures in older adults: using hip screws versus replacing part or all of the hip. It may help find which option works best for healing and returning to movement.

Three vs four screws to fix a broken hip bone

This trial compares using three versus four screws to hold a femoral neck fracture (a break in the hip bone near the joint). It aims to see which method works better for healing and recovery after internal fixation surgery.

Compare two antibiotic routes for infected broken bones after surgery

This Phase 3 trial tests whether giving antibiotics by mouth (PO) works as well as giving antibiotics through a vein (IV) for an infected fracture that has not healed after prior surgery. It may help you understand which approach is safer and more effective for getting the bone to heal.

Comparing two bandages after wrist fracture surgery

This study compares two ways to support the wrist after surgery for a broken distal radius. One uses a compression bandage, the other uses a splint. The goal is to see which helps you heal and return to daily activities faster.

Hip surgery comparison for nondisplaced femoral neck fracture

This trial compares two types of surgery—plates and screws versus hip replacement—for a specific type of hip fracture that is not shifted out of place. The goal is to see which option helps people recover better.

Surgery vs. early rehab for pelvic fractures in older adults

This study compares two treatments for a specific type of pelvic fracture (LC1) in people 60 and older: surgery to fix the bone early, or non-surgical care with early rehabilitation. The goal is to see which approach leads to better recovery.

Fracture healing after hip surgery in younger adults

This trial tests whether a new surgical method helps hip fractures heal better in adults aged 18 to 64. It uses special X-rays to track how the bone moves over time.

Lidocaine infusion to reduce opioid use in arm fracture surgery

This study tests whether giving a pain-relieving medication called lidocaine through an IV during arm fracture surgery can reduce how much opioid pain medication (like morphine) children need after surgery. The goal is to help manage pain better while using fewer opioids.

Extended Antibiotics for Diabetic Leg Fracture Surgery

This study tests whether taking antibiotics for a longer time helps prevent infections in people with poorly controlled diabetes who need surgery for a lower leg or foot fracture. Since diabetes makes infections more likely after surgery, extra antibiotics might reduce that risk.

Compare hip surgery methods for new pelvic bone fractures

This study compares two ways of fixing a recently broken acetabulum (the hip socket): one method keeps/repairs the socket (ORIF) and the other replaces it (THA). It aims to find which surgery approach leads to better outcomes for people who can have surgery soon after the injury.

Non-opioid pain control after fracture surgery

This trial tests a combination of non-opioid medications to manage pain after surgery for a broken bone, aiming to reduce or avoid the use of opioids. It may help you control pain without the risks of strong painkillers.

Robot-assisted surgery for thigh bone fractures

This trial tests whether a robot can help doctors fix a broken thigh bone (femur) more precisely than standard surgery. If you have a recent, closed thigh bone fracture, this study might help improve your recovery and alignment.

Bleeding study for hip fracture patients on blood thinners

This trial looks at patients with a broken hip who take a type of blood thinner called a NOAC. It measures bleeding during surgery to fix the hip, without stopping or delaying the surgery. The goal is to see if it is safe to operate right away.

Hip Replacement vs. Screws for Hip Fracture Recovery

This study compares two types of surgery for a specific hip fracture in older adults: hip replacement versus inserting screws to hold the bone in place. It aims to see which helps patients recover faster and get back to moving around sooner.

Home light therapy for wrist fracture recovery

This study tests a special light device you can use at home to see if it helps reduce pain and improve recovery after surgery for a broken wrist (distal radius fracture). It compares the light treatment to a placebo (sham) device, so you won't know which one you get.

Knee Injection During Kneecap Fracture Surgery

This trial tests adding a pain-relieving injection (a 'cocktail' of medicines) into the knee joint during surgery to fix a broken kneecap. The goal is to see if this extra injection helps reduce pain and improve recovery after the operation.

Surgery for thigh bone cancer: reconstruction vs. repair

This trial compares two types of surgery to fix the top part of the thigh bone that has been weakened or broken by cancer that spread from another part of the body. One surgery replaces the damaged area with an artificial joint, and the other repairs it using metal plates and screws.

Casting vs surgery for elbow bone fractures in children

This study compares two treatments—casting or an operation—for a specific elbow fracture in children. It aims to see which approach works best for healing and recovery after a recent fracture.

Comparing two surgeries for complex ankle breaks in older adults

This trial tests two ways to fix complicated ankle and lower leg fractures in people over 65. It compares using a nail through the heel versus plates and screws to see which helps you heal and move better.