Clinical trials
Frail clinical trials
Below are recruiting frail clinical trials, each written for real people, not researchers. We’re tracking 90 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07643064Recruiting
Exercise and health checks for frail older adults
This study tests whether a combination of tailored exercise classes and comprehensive health assessments can improve strength, function, and overall well-being in older adults who are frail or at risk of becoming frail. You would attend supervised exercise sessions and receive personalized health evaluations at a primary care center.
Tacoronte, Santa Cruz de TenerifeAges 70 years+ - NCT06729502Recruiting
Frailty Scale for Older Adults in the ICU
This study uses a simple picture-based scale to measure frailty in older adults (60+) who were admitted to the intensive care unit. It aims to better understand how frailty affects recovery in this setting.
Petah TikvaAges 60 years+ - NCT07839247RecruitingPhase 2
Two oral drugs for brain lymphoma in older adults
This trial tests a combination of two oral medications (zanubrutinib and lenalidomide) for older adults with a certain type of brain lymphoma. The goal is to see if this treatment can help control the disease with manageable side effects.
Beijing, Beijing MunicipalityAges 70 years+ - NCT07564076Enrolling by invitation
Exercise Programs for Frail Older Adults
This study compares different exercise programs designed specifically for frail older adults to see which approach works best. If you're experiencing weakness and slowness, this trial may help you regain strength and function.
IstanbulAges 65 years+ - NCT07292428Recruiting
Cognitive-motor rehab for frail older adults
This trial tests a combined cognitive and physical training program for frail individuals aged 65 to 90. It aims to improve both thinking and movement abilities to help you stay active and independent.
Rome, ItalyAges 65–90 - NCT07211334Recruiting
High-intensity vs. moderate exercise for frail older adults
This study compares two types of exercise programs for older adults who are frail. It tests whether short bursts of intense exercise (interval training) or steady moderate exercise improves their health and strength more.
GrenobleAges 70 years+ - NCT07136935Recruiting
Integrating traditional Chinese and Western medicine for frail elderly recovery
This study tests a care model that combines traditional Chinese and Western medicine to help frail elderly patients recover function after a hospital stay for an acute illness. If you or a loved one is over 75, living with conditions like Parkinson's, COPD, mild dementia, or kidney disease, and recently lost strength or ability to do daily tasks, this may offer a supportive approach to regain independence.
TaichungAges 20 years+ - NCT06849557Recruiting
Chair exercises for frail older adults in nursing homes
This trial tests if chair-based video games (exergaming) can help improve strength and mobility in older adults who are frail or pre-frail and live in nursing homes. It is designed for people who can sit on a chair or wheelchair without help.
KowloonAges 60 years+ - NCT06127563Recruiting
Better vaccine care for frail patients
This trial tests whether offering vaccines more carefully to frail patients in certain hospital departments improves their health. It is open to adults living in Lazio who are being treated in one of five specific departments.
Rome, LazioAges 18 years+ - NCT06027554RecruitingPhase 2
MitoQ for frailty, walking, memory, and blood flow in older adults
This trial tests whether a supplement called MitoQ can improve blood vessel health, walking speed, and thinking skills in older adults who are frail or have mild memory problems. It aims to see if MitoQ helps maintain independence and quality of life.
Farmington, ConnecticutAges 65–80 - NCT04366388Recruiting
Testing a new way to check frailty in hospitalized seniors
This trial studies a new tool that helps doctors measure “frailty” in older adults who are hospitalized. It may help hospitals identify risks earlier and tailor care for seniors who are more vulnerable.
Vancouver, British ColumbiaAges 65 years+ - NCT04518423Recruiting
Study frailty and fitness changes in older adults living at home
This study looks at how “frailty” (lower strength and resilience) and “pre-frailty” change over time in older adults who live at home. It may help researchers understand what factors affect aging and strength, so future care can start earlier.
OpoleAges 65 years+ - NCT05635877RecruitingPhase 4
Low-dose heart-rate medicine after surgery in frail older adults
This trial tests whether a low dose of esmolol (a short-acting heart-rate medicine) can reduce heart muscle injury after non-heart surgery in older, frail people. It may help lower the chance of heart-related complications around the time of surgery.
Jinan, ShandongAges 65–90 - NCT03209414Recruiting
Study of frailty in heart patients receiving heart care
This trial looks at “frailty,” meaning reduced strength and resilience, in older adults with coronary artery disease who are getting heart care. It may help doctors better understand which patients are more at risk and how care decisions could be improved.
Zabrze, Upper SilesiaAges 65 years+ - NCT04087031Recruiting
Tech-based rehab for early Parkinson’s symptoms in older adults
This trial tests an innovative, technology-supported rehabilitation program to help older adults with early-stage Parkinson’s disease improve daily function. It may be helpful if your symptoms are mild and your treatments have been stable for at least a month.
AnconaAges 65 years+ - NCT06444321Recruiting
Integrated care for frail patients with heart failure
This trial tests a special care program for people with both frailty (being weak or vulnerable) and heart failure (when the heart doesn't pump well). The program brings together different types of support to help you manage your health better after a hospital stay.
Drammen, AkershusAges 18 years+ - NCT07828847Recruiting
Exercise and muscle health in older adults with diabetes
This study looks at how exercise affects muscle cell function in older adults with type 2 diabetes and frailty. It may help find ways to improve strength and independence in aging.
ValenciaAges 18–83 - NCT07824700Recruiting
Prehabilitation for frail patients before heart surgery
This program helps mildly or moderately frail patients get physically stronger before their heart surgery or procedure. It is designed to improve recovery and outcomes by starting exercises and support during the waiting period.
Hong KongAges 18 years+ - NCT07732530Recruiting
Acupoint Stimulation and Exercise for Pre-Frail Older Adults
This study tests whether combining acupoint stimulation (a type of pressure on specific body points) with exercise can help older adults who are starting to become frail. It aims to improve strength and daily function.
TainanAges 50 years+ - NCT04461301Recruiting
Exercise training before surgery for older adults with low fitness
This study tests a pre-surgery “exercise and health training” program for older adults who are having major surgery and are already less fit than expected. It aims to help people tolerate surgery better and reduce complications by improving fitness beforehand.
Bern, Canton of BernAges 65 years+ - NCT06617806Recruiting
Preventing falls in very old, active adults
This trial tests if advanced practice nurses can help prevent falls in robust adults aged 80 and older. It may help you stay independent and avoid injuries.
Nantes, Loire-AtlantiqueAges 80 years+ - NCT07642765Recruiting
Frailty Score and Blood Pressure Changes During Surgery
This study looks at a simple scoring system (EASIX) that predicts whether older or frail patients will experience dangerous blood pressure drops when anesthesia is given before surgery. Understanding this risk might help doctors better protect vulnerable patients during their operations.
KonyaAges 18 years+ - NCT07637383Recruiting
Exercise Program to Improve Daily Function in Hospital Care
This study tests whether a structured exercise program can help patients in intermediate care hospitals regain their ability to do everyday activities like walking and self-care. The program is designed for people recovering from illness or injury.
Manresa, BarcelonaAges 65 years+ - NCT06671353Recruiting
Video decision support for advance care planning in frail older adults
This trial tests if watching a video helps older adults with frailty make informed decisions about future medical care. You may be able to join if you are 65 or older, have been diagnosed with frailty, and can watch a video and sign a consent form.
TaipeiAges 65 years+
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Common questions
- Are there clinical trials for frail?
- Yes. Clin2 currently lists 90 recruiting frail studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a frail trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a frail trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.