Clinical trials
Frail clinical trials
Below are recruiting frail clinical trials, each written for real people, not researchers. We’re tracking 95 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07643064Recruiting
Exercise and health checks for frail older adults
This study tests whether a combination of tailored exercise classes and comprehensive health assessments can improve strength, function, and overall well-being in older adults who are frail or at risk of becoming frail. You would attend supervised exercise sessions and receive personalized health evaluations at a primary care center.
Tacoronte, Santa Cruz de TenerifeAges 70 years+ - NCT06729502Recruiting
Frailty Scale for Older Adults in the ICU
This study uses a simple picture-based scale to measure frailty in older adults (60+) who were admitted to the intensive care unit. It aims to better understand how frailty affects recovery in this setting.
Petah TikvaAges 60 years+ - NCT06849557Recruiting
Chair exercises for frail older adults in nursing homes
This trial tests if chair-based video games (exergaming) can help improve strength and mobility in older adults who are frail or pre-frail and live in nursing homes. It is designed for people who can sit on a chair or wheelchair without help.
KowloonAges 60 years+ - NCT06127563Recruiting
Better vaccine care for frail patients
This trial tests whether offering vaccines more carefully to frail patients in certain hospital departments improves their health. It is open to adults living in Lazio who are being treated in one of five specific departments.
Rome, LazioAges 18 years+ - NCT06363942Recruiting
Video exercise program for fall prevention in frail older adults
This trial tests a personalized video-based exercise program to help older adults who are frail or pre-frail prevent falls. It may be a good fit if you are relatively healthy aside from frailty concerns.
Montreal, QuebecAges 70 years+ - NCT07292428Recruiting
Cognitive-motor rehab for frail older adults
This trial tests a combined cognitive and physical training program for frail individuals aged 65 to 90. It aims to improve both thinking and movement abilities to help you stay active and independent.
Rome, ItalyAges 65–90 - NCT04366388Recruiting
Testing a new way to check frailty in hospitalized seniors
This trial studies a new tool that helps doctors measure “frailty” in older adults who are hospitalized. It may help hospitals identify risks earlier and tailor care for seniors who are more vulnerable.
Vancouver, British ColumbiaAges 65 years+ - NCT06027554RecruitingPhase 2
MitoQ for frailty, walking, memory, and blood flow in older adults
This trial tests whether a supplement called MitoQ can improve blood vessel health, walking speed, and thinking skills in older adults who are frail or have mild memory problems. It aims to see if MitoQ helps maintain independence and quality of life.
Farmington, ConnecticutAges 65–80 - NCT07136935Recruiting
Integrating traditional Chinese and Western medicine for frail elderly recovery
This study tests a care model that combines traditional Chinese and Western medicine to help frail elderly patients recover function after a hospital stay for an acute illness. If you or a loved one is over 75, living with conditions like Parkinson's, COPD, mild dementia, or kidney disease, and recently lost strength or ability to do daily tasks, this may offer a supportive approach to regain independence.
TaichungAges 20 years+ - NCT07211334Recruiting
High-intensity vs. moderate exercise for frail older adults
This study compares two types of exercise programs for older adults who are frail. It tests whether short bursts of intense exercise (interval training) or steady moderate exercise improves their health and strength more.
GrenobleAges 70 years+ - NCT07564076Enrolling by invitation
Exercise Programs for Frail Older Adults
This study compares different exercise programs designed specifically for frail older adults to see which approach works best. If you're experiencing weakness and slowness, this trial may help you regain strength and function.
IstanbulAges 65 years+ - NCT07275216RecruitingPhase 2
A study of pembrolizumab plus chemo for frail Hodgkin lymphoma patients
This trial tests a combination of the immunotherapy drug pembrolizumab with chemotherapy for people with newly diagnosed Hodgkin lymphoma who are too frail for standard treatment. The goal is to find a safer, effective option for patients who are older or have other health issues.
Duarte, CaliforniaAges 18 years+ - NCT05946109Recruiting
Exercise program for frail older adults over 70
This trial studies whether a structured exercise program can improve health and function in frail adults age 70 and older. It may help you build strength, energy, and mobility if you meet frailty and safety requirements.
Brussels, Brussels CapitalAges 70 years+ - NCT02339012Recruiting
Genetic study of healthy and frail aging
This study looks at genes and aging by comparing healthy people, those who are not healthy or frail, and those who are frail. You'll provide blood samples and get MRI scans to help researchers understand aging better.
Baltimore, MarylandAges 20–120 - NCT05875038Recruiting
Smart fall-monitoring video with telealerts versus alerts alone
This study tests whether a smart video monitoring system with emergency-style alerts works better than alerts alone for preventing or responding to falls at home. It focuses on older adults who have recently fallen and may find returning home unsafe.
Amiens, PicardieAges 75 years+ - NCT06616129Recruiting
Geriatric risk assessment for older heart surgery patients
This study tests whether a special geriatric risk assessment and shared decision-making conversation helps older patients (70+) and their doctors choose the best treatment for heart surgery. It aims to improve quality of life by tailoring decisions to each person's health risks.
Groningen, Provincie GroningenAges 70 years+ - NCT06192082Recruiting
Heart risks during painless stomach scope in frail elderly
This study looks at whether older, frail patients have heart problems during a painless stomach scope (gastroscopy). It aims to find safer ways to give sedation for these patients.
Beijing, Beijing MunicipalityAges 65–100 - NCT05635877RecruitingPhase 4
Low-dose heart-rate medicine after surgery in frail older adults
This trial tests whether a low dose of esmolol (a short-acting heart-rate medicine) can reduce heart muscle injury after non-heart surgery in older, frail people. It may help lower the chance of heart-related complications around the time of surgery.
Jinan, ShandongAges 65–90 - NCT05107947Recruiting
Dynamic room lighting to improve sleep and daily body rhythm
This study tests whether changing the light in a hospital room can improve sleep and help your body clock work better in older adults. It may be most helpful if sleep problems or irregular daily rhythms are affecting you in the hospital.
MalmöAges 65 years+ - NCT07637383Recruiting
Exercise Program to Improve Daily Function in Hospital Care
This study tests whether a structured exercise program can help patients in intermediate care hospitals regain their ability to do everyday activities like walking and self-care. The program is designed for people recovering from illness or injury.
Manresa, BarcelonaAges 65 years+ - NCT07642765Recruiting
Frailty Score and Blood Pressure Changes During Surgery
This study looks at a simple scoring system (EASIX) that predicts whether older or frail patients will experience dangerous blood pressure drops when anesthesia is given before surgery. Understanding this risk might help doctors better protect vulnerable patients during their operations.
KonyaAges 18 years+ - NCT07086716Recruiting
Frailty study for hip or knee replacement patients
This study looks at frailty in people who have had a planned hip or knee replacement. It aims to understand how frailty affects recovery.
Rovato, BSAges 18 years+ - NCT07572851Enrolling by invitation
Exercise Program for Preventing Falls in Older Adults
This study looks at how an exercise and wellness program helps older adults stay stronger and reduce their risk of falling. Researchers will track changes in your physical function and balance over time.
A Lama, PontevedraAges 70 years+ - NCT06628895Recruiting
Modified Poco-Poco exercise for pre-frailty
This study tests whether a special exercise routine called Modified Poco-Poco can improve frailty and certain biological markers (DNA changes, GDF15, and Lamin A). It may help people who are beginning to feel weaker and want to try a gentle exercise program.
Bandung, West JavaAges 60 years+
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Common questions
- Are there clinical trials for frail?
- Yes. Clin2 currently lists 95 recruiting frail studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a frail trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a frail trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.