Clinical trials
Frail Elderly Patients clinical trials
Below are recruiting frail elderly patients clinical trials, each written for real people, not researchers. We’re tracking 35 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06469437Recruiting
Geriatric check for older adults with type 2 diabetes
This study looks at how a full health check for older adults with type 2 diabetes can help doctors choose the best treatment plan. It aims to improve care for people 60 and older.
Porto Alegre, Rio Grande do SulAges 60 years+ - NCT07136935Recruiting
Integrating traditional Chinese and Western medicine for frail elderly recovery
This study tests a care model that combines traditional Chinese and Western medicine to help frail elderly patients recover function after a hospital stay for an acute illness. If you or a loved one is over 75, living with conditions like Parkinson's, COPD, mild dementia, or kidney disease, and recently lost strength or ability to do daily tasks, this may offer a supportive approach to regain independence.
TaichungAges 20 years+ - NCT07211334Recruiting
High-intensity vs. moderate exercise for frail older adults
This study compares two types of exercise programs for older adults who are frail. It tests whether short bursts of intense exercise (interval training) or steady moderate exercise improves their health and strength more.
GrenobleAges 70 years+ - NCT06202118Recruiting
Alpha radiation therapy for breast cancer in older or frail patients
This trial tests a new type of radiation therapy (DaRT) that uses tiny, implantable seeds to deliver targeted alpha radiation to breast tumors. It is designed for older patients (65+) or those who are too frail for surgery, offering a less invasive option for controlling the cancer.
JerusalemAges 65–120 - NCT06192082Recruiting
Heart risks during painless stomach scope in frail elderly
This study looks at whether older, frail patients have heart problems during a painless stomach scope (gastroscopy). It aims to find safer ways to give sedation for these patients.
Beijing, Beijing MunicipalityAges 65–100 - NCT05635877RecruitingPhase 4
Low-dose heart-rate medicine after surgery in frail older adults
This trial tests whether a low dose of esmolol (a short-acting heart-rate medicine) can reduce heart muscle injury after non-heart surgery in older, frail people. It may help lower the chance of heart-related complications around the time of surgery.
Jinan, ShandongAges 65–90 - NCT07086716Recruiting
Frailty study for hip or knee replacement patients
This study looks at frailty in people who have had a planned hip or knee replacement. It aims to understand how frailty affects recovery.
Rovato, BSAges 18 years+ - NCT06874413Enrolling by invitation
Exercise program for frail older adults before hernia surgery
This study tests whether a supervised exercise program before hernia repair surgery helps frail older adults recover better. The program includes physical exercises and breathing muscle training.
Greenville, South CarolinaAges 65 years+ - NCT06530511RecruitingPhase 2
PRO trial for elderly, frail patients with a type of lymphoma
This trial tests a combination of three drugs (Polatuzumab, Rituximab, and Orelabrutinib) for elderly patients who are frail or over 80 with a specific type of untreated diffuse large B-cell lymphoma (non-GCB DLBCL). The goal is to see if this drug combo is safe and effective for those who may not tolerate standard chemotherapy.
Nantong, JiangsuAges 60 years+ - NCT07441382Recruiting
Comparing treatments for frail older adults with atrial fibrillation
This study tests whether combining a heart procedure (catheter ablation) with a device to close the left atrial appendage (LAAO) is safer or better than blood thinners alone for frail patients 75 years or older with atrial fibrillation and high stroke risk. It aims to find a treatment that reduces stroke while lowering bleeding risks.
Guangzhou, GuangdongAges 75 years+ - NCT07463352Recruiting
Pre-surgery nutrition for frail seniors with hip fractures
This study tests if giving a special protein drink before surgery helps frail older adults with a broken hip recover better. It might reduce complications after surgery.
DüzceAges 65 years+ - NCT04436991Recruiting
Testing antibiotic doses in older adults in the emergency room
This study looks at how best to dose certain antibiotics in people age 75 and older who are admitted to a geriatric (older-adult) hospital unit. It aims to measure antibiotic levels in the body to see whether dosing can be improved for older patients.
GhentAges 75 years+ - NCT05952024RecruitingPhase 2
Acalabrutinib plus rituximab for older untreated DLBCL
This trial studies the combination of acalabrutinib and rituximab in older or frail people with newly diagnosed DLBCL (a type of lymphoma). It aims to see how well this treatment works and how safe it is for people who may not be able to tolerate standard chemotherapy.
Berkeley, CaliforniaAges 65–99 - NCT06552234RecruitingPhase 2
Study of repotrectinib for older or frail patients with ROS1-positive lung cancer
This trial tests an oral targeted therapy called repotrectinib in people with advanced non-small cell lung cancer (NSCLC) that has a change in the ROS1 gene. It is designed for patients who are either 70 or older, or have a lower performance status (ECOG 2 or higher), meaning they may be more frail or have more symptoms. The goal is to see if repotrectinib can help shrink or control the cancer.
Aix-en-Provence, Bouches Du RhôneAges 18 years+ - NCT07015112Recruiting
Medication check for older adults with multiple conditions
This trial tests a team-based approach to review and improve medication use for older adults (65+) who have three or more chronic conditions and are staying in an intermediate care hospital. The goal is to make sure your medicines are as safe and effective as possible.
Barcelona, BarcelonaAges 65 years+ - NCT04765514RecruitingPhase 2
Chemo with radiation versus chemo alone for older brain tumor patients
This trial compares two standard treatments for newly diagnosed glioblastoma (a serious brain cancer) in older and frail patients: chemo plus radiation versus chemo alone. It may help determine which approach works best and is safest for people in your age and health group.
Calgary, AlbertaAges 65 years+ - NCT06671353Recruiting
Video decision support for advance care planning in frail older adults
This trial tests if watching a video helps older adults with frailty make informed decisions about future medical care. You may be able to join if you are 65 or older, have been diagnosed with frailty, and can watch a video and sign a consent form.
TaipeiAges 65 years+ - NCT06616129Recruiting
Geriatric risk assessment for older heart surgery patients
This study tests whether a special geriatric risk assessment and shared decision-making conversation helps older patients (70+) and their doctors choose the best treatment for heart surgery. It aims to improve quality of life by tailoring decisions to each person's health risks.
Groningen, Provincie GroningenAges 70 years+ - NCT07259499Recruiting
Predictors of emergency visits in frail older adults
This study looks at why frail older adults go to the emergency room. Researchers want to see if blood tests and brain scans can help predict who needs emergency care. Participation involves one interview and having had a recent brain scan and blood work.
Pisa, PisaAges 65 years+ - NCT04461301Recruiting
Exercise training before surgery for older adults with low fitness
This study tests a pre-surgery “exercise and health training” program for older adults who are having major surgery and are already less fit than expected. It aims to help people tolerate surgery better and reduce complications by improving fitness beforehand.
Bern, Canton of BernAges 65 years+ - NCT06444321Recruiting
Integrated care for frail patients with heart failure
This trial tests a special care program for people with both frailty (being weak or vulnerable) and heart failure (when the heart doesn't pump well). The program brings together different types of support to help you manage your health better after a hospital stay.
Drammen, AkershusAges 18 years+ - NCT05993754Recruiting
Preventing confusion after surgery in frail older adults
This study tests whether a special nursing care plan can help prevent confusion after surgery in older adults who are frail. If you are 65 or older, having planned surgery, and generally healthy enough, this trial may be an option.
Santiago, Santiago MetropolitanAges 65 years+ - NCT04087031Recruiting
Tech-based rehab for early Parkinson’s symptoms in older adults
This trial tests an innovative, technology-supported rehabilitation program to help older adults with early-stage Parkinson’s disease improve daily function. It may be helpful if your symptoms are mild and your treatments have been stable for at least a month.
AnconaAges 65 years+ - NCT06857981Recruiting
Prepare for Your Surgery: A Program for Frail Patients
This trial is for people who are frail and planning to have elective surgery in at least 4 weeks. It focuses on a program to help you prepare for your surgery, so you may have a better recovery.
Santiago, Santiago MetropolitanAges 18 years+
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Common questions
- Are there clinical trials for frail elderly patients?
- Yes. Clin2 currently lists 35 recruiting frail elderly patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a frail elderly patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a frail elderly patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.