Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,474 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02504788Recruiting
Protect the brain’s memory area during whole-brain radiation
This study tests whether avoiding the hippocampus (a part of the brain important for memory) during whole-brain radiotherapy can slow down thinking and memory decline. It may help some people preserve neurocognitive function while still treating brain metastases.
TaoyuanAges 18–84 - NCT04006561Recruiting
Brain lymphoma study using targeted whole-brain radiation
This trial studies how newly diagnosed primary central nervous system (brain) non-Hodgkin lymphoma responds to a specific type of radiation to the whole brain, and it also looks at changes in thinking, mood, and behavior. It may help doctors understand how this treatment affects day-to-day brain function.
TaoyuanAges 18–80 - NCT05848609Recruiting
Quality of life study for older adults having robotic colon surgery
This study looks at how older people feel and function after robotic surgery for colorectal cancer. It may help doctors understand what to expect and how to better support quality of life during recovery.
BrusselsAges 70 years+ - NCT04019548RecruitingPhase 3
Test swallowing and quality of life during chemo-radiation for throat cancer
This study looks at how well people swallow and how their quality of life changes during standard chemo-radiation for newly diagnosed throat (oropharyngeal) cancer. The goal is to better understand swallowing side effects so care can improve.
BrusselsAges 18 years+ - NCT05865093Recruiting
Check early vision changes in infants at risk for brain vision problems
This pilot study looks at early vision (what babies can see and how their eyes respond) in children who have risk factors for future “cerebral visual impairment,” meaning vision problems caused by the brain. It may help doctors spot issues earlier and better understand which early visual signs matter.
RomeAges 2 days–3 years - NCT03002272Recruiting
Long-term follow-up after TAVR or surgical valve replacement
This study checks how well an aortic valve replacement works many years after the procedure. It may help doctors understand long-term valve function and identify people who might need closer monitoring.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05921422Recruiting
Study of thinking skills in children with cerebral palsy
This study looks at how children’s and teens’ thinking and learning work in everyday school life. It may help researchers better understand strengths and challenges in cerebral palsy to improve support.
CopenhagenAges 11–15 - NCT05937334Recruiting
Long-term study of asthma in adults in China
This study follows adults with asthma over about 2 years to learn more about asthma and how people do over time. If you qualify, you’ll be asked to join regular visits and follow the study plan.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05963126Recruiting
Fetuin A test to predict kidney function decline
This study looks at a blood protein called fetuin A to see if it can forecast worsening kidney function over time in people with treated high blood pressure. It may help identify who is at higher risk for kidney decline so care can be adjusted earlier.
Ostrava, Czech RepublicAges 18–100 - NCT05962190Recruiting
Short-term extra fat intake to study liver metabolism
This study tests what happens to the liver and fat metabolism when you eat extra fat for a short time. It may help researchers understand how diet affects liver function and metabolism in otherwise stable adults.
OxfordAges 18–65 - NCT05983107RecruitingPhase 2
Chidamide/Everolimus for advanced breast cancer
This trial tests a combination of two drugs, chidamide and everolimus, for people with advanced HR+/HER2- breast cancer. It aims to see if the combination works for tumors with or without a PIK3CA gene mutation. You may be able to join if you've had previous treatment with CDK4/6 inhibitors and up to two prior chemotherapies.
Beijing, Beijing MunicipalityAges 18–75 - NCT05985447Recruiting
Menopause and blood cell function study
This study looks at how menopause affects blood cells and platelets in people with heart or lung conditions. It may help understand why risks change after menopause.
DüsseldorfAges 18 years+ - NCT05988879Recruiting
Functional cure for hepatitis B in HIV/HBV co-infection
This trial tests whether people with both HIV and hepatitis B can achieve a functional cure for hepatitis B. It aims to see if current treatment can be stopped safely after the hepatitis B virus is no longer active.
Guangzhou, GuangdongAges 18–65 - NCT05689866Recruiting
Study of bladder and sphincter symptoms in functional neurological disorders
This study looks at bladder and sphincter (urine control) symptoms in people with functional neurological disorders. It may help doctors understand what causes these symptoms and how to better treat them.
BobignyAges 18 years+ - NCT05825092RecruitingPhase 2
Early testosterone gel for people on breathing machines
This Phase 2 study tests whether starting testosterone gel soon after ICU admission can improve physical performance in critically ill adults who need a breathing machine for more than 48 hours. It’s also designed to check safety in this setting.
BordeauxAges 18–79 - NCT06082648Recruiting
Brain and bowel recovery after ultra-low rectal cancer surgery
This trial studies how a noninvasive brain stimulation technique (TMS) and brain scans (fMRI) might help improve bowel function and quality of life after surgery for ultra-low rectal tumors. It is for patients who have had a specific surgery (intersphincteric resection) and a temporary ileostomy.
ShanghaiAges 18–75 - NCT06104696Recruiting
Comprehensive Geriatric Assessment in Kidney Transplant Patients Over 60
This study looks at how a full health review (geriatric assessment) can help older adults who are getting or have gotten a new kidney. It aims to improve care and outcomes for patients aged 60 and over.
PragueAges 60 years+ - NCT05048862Recruiting
Brain scan and tests for neuromuscular conditions
This study compares people with neuromuscular disorders to healthy people using questionnaires and brain/neurological tests. It may help researchers understand how these conditions affect the brain and nervous system.
TaipeiAges 20 years+ - NCT06137196Recruiting
Lung function risks after severe pneumonia in AIDS patients
This study looks at why some people with AIDS who recover from severe pneumonia later have trouble breathing. Researchers want to find risk factors so they can help prevent lung damage.
Guangzhou, GuangdongAges 18–65 - NCT02023060Recruiting
Improving function and quality of life after heart valve repair
This study looks at how a less invasive heart valve procedure affects your day-to-day functioning and overall quality of life. If you’re already being considered for a transcatheter (catheter-based) valve replacement, you may be able to join to help understand what improvements patients experience.
JerusalemAges 18–110 - NCT04792892Recruiting
Study of quality of life after new anal cancer diagnosis
This study looks at how people’s day-to-day functioning and quality of life change after an anal cancer diagnosis. It mainly enrolls adults recently diagnosed to understand outcomes early on.
GothenburgAges 18 years+ - NCT05892133Recruiting
Exercise program before knee replacement to improve recovery
This trial studies whether doing a structured exercise or “prehab” program before total knee replacement can improve knee function and patient satisfaction after surgery. It may help you recover better and feel more confident in your outcome.
Molde, Møre og RomsdalAges 50–80 - NCT07863219Recruiting
Cognitive effects of a 10-week exercise program for Parkinson's disease
This trial tests whether a 10-week program combining exercise and other activities can improve thinking and memory in people with Parkinson's disease.
Ghent, Oost-VlaanderenAges 18 years+ - NCT07855029Recruiting
Quality of life after hepatitis B treatment outcomes
This study looks at how different outcomes of chronic hepatitis B treatment affect patients' quality of life. It includes people who have been functionally cured, those still on treatment, those who relapsed, and healthy controls to compare.
GuangzhouAges 18–65
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,474 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.