Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,577 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04381663Enrolling by invitation
Tracking symptoms in degenerative neck spine narrowing
This study follows adults with degenerative narrowing in the neck spine to see how symptoms and function change over time. It may help doctors better understand which patients improve or worsen, and why.
BaselAges 18 years+ - NCT04393181Recruiting
Study how donor heart function affects transplant outcomes
This study looks at how well donor hearts work and how that affects outcomes after heart transplantation. It may help transplant teams choose and use donor hearts more effectively.
Gothenburg, Västra Götaland CountyAges 18 years+ - NCT04030650Recruiting
Study of walking expectations on slopes and stairs after limb amputation
This study looks at how people with a leg amputation think about and perform walking on stairs and up/down slopes. It may help researchers understand what supports safer, more confident mobility.
DijonAges 18 years+ - NCT05869812RecruitingPhase 2
HMB supplement study to help recovery after surgery
This trial tests whether taking an HMB supplement after surgery can help improve muscle size and function during recovery. It may be helpful if you are a female athlete planning rehab at a specific physical therapy clinic.
Overland Park, KansasAges 18–45 - NCT03662776Enrolling by invitation
How past eye-cancer treatment affects survivors’ well-being
This study looks at how different treatments for one affected eye retinoblastoma may affect survivors’ emotional and social functioning. It may help doctors understand which treatment approaches are linked with better day-to-day well-being over time.
New York, New YorkAges 8–17 - NCT05874102Enrolling by invitation
Testing how body position affects swallowing in infants
This study checks whether changing an infant’s body position (for example, side-lying or more upright) changes how safely they swallow. It focuses on infants who have swallowing difficulty seen during a special swallow test with imaging.
Hartford, ConnecticutAges 9 months–1.1 years - NCT05689866Recruiting
Study of bladder and sphincter symptoms in functional neurological disorders
This study looks at bladder and sphincter (urine control) symptoms in people with functional neurological disorders. It may help doctors understand what causes these symptoms and how to better treat them.
BobignyAges 18 years+ - NCT03981653Recruiting
Placenta study around normal third-trimester pregnancy
This study looks at how the placenta is working in pregnancies that are planned for cesarean delivery after at least 37 weeks. Researchers compare different pregnancy situations (including some common complications) and check placenta function to better understand placental health.
CréteilAges 18 years+ - NCT04498806Enrolling by invitation
Using activity trackers to measure function in neck myelopathy
This study uses a wearable activity tracker (Fitbit app on your phone) to track how your physical function changes around the time of neck decompression surgery. It may help doctors better measure recovery and day-to-day movement after surgery.
Salt Lake City, UtahAges 18–90 - NCT04165746Recruiting
Early care program for very young children in foster systems
This study looks at how an early support program affects the development of infants who are newly entering institutional care or foster care in the São Paulo area. It may help families and caregivers support healthy growth during a critical first period.
São Paulo, São PauloAges Up to 2 years - NCT04253379Recruiting
Study of social understanding in children with epilepsy
This study looks at how children with epilepsy understand social cues, compared with other children the same age. You may be asked to complete simple thinking and social tasks to see what differences exist and what they might mean.
ReimsAges 6–12 - NCT04045600Recruiting
Refining communication training for kids with behavior challenges
This study tests an improved version of functional communication training for children ages 3 to 17 whose destructive behavior (like hitting or yelling) happens often and is fueled by social attention. It aims to help children learn better ways to get attention instead of using hard-to-manage behaviors.
Somerset, New JerseyAges 3–17 - NCT04628429Recruiting
Study CGRP blocker effects on migraine and body nerve function
This study tests a CGRP-blocking antibody to see how it affects migraine symptoms and the body’s automatic (involuntary) nerve functions. It may help people with migraine who have already tried several preventive medicines.
ViennaAges 18–64 - NCT04474106Recruiting
Shock wave therapy for new spinal cord injuries
This study tests whether extracorporeal shock wave therapy (non-surgical shock waves delivered from outside the body) can improve movement and sensation after a recent spinal cord injury. It may help people recover motor (movement) and sensory (feeling) function within months after injury.
Innsbruck, TyrolAges 18–99 - NCT04246138Recruiting
Robot-assisted knee replacement alignment: best function
This trial compares two types of robot-guided knee replacement alignment to see which one helps people do everyday activities better after surgery. If you have “wear-and-tear” knee arthritis, you may be offered one of the two surgical alignment approaches as part of a study.
Hull, East YorkshireAges 18–90 - NCT04458584Recruiting
Thumb surgery trial comparing treatments for basal joint arthritis
This study looks at how well different thumb (basal joint) surgery approaches restore strength and function. You would be having planned (non-replacement) thumb surgery, and your chosen surgeon would care for you while researchers compare outcomes.
Lebanon, New HampshireAges 21 years+ - NCT02924818Recruiting
Research study for adults with long-term breathing lung diseases
This study enrolls adults with chronic lung conditions like COPD, cystic fibrosis, bronchiectasis, or interstitial lung disease. It’s designed to learn more about these illnesses and to develop better ways to study or improve care.
ReimsAges 18 years+ - NCT05593627RecruitingPhase 4
Lithium to improve sleep and thinking after heart surgery
This trial tests whether lithium carbonate can improve sleep and thinking (cognitive function) after heart valve surgery that uses a heart-lung machine. It may help some people who have trouble sleeping or thinking after surgery, but it excludes people with significant sleep or thinking problems before surgery.
Shenyang, LiaoningAges 18–65 - NCT03137095Recruiting
Study how chemotherapy affects brain function in breast cancer
This study looks at changes in thinking and brain function in people with early to locally advanced breast cancer before and during chemotherapy. You may also be offered a brain MRI in a separate optional part of the research to learn more about brain changes.
Rochester, New YorkAges 21 years+ - NCT02382601Recruiting
Study of pregnancies with slow fetal growth
This study follows pregnancies where the baby appears smaller than expected on ultrasound. It may help researchers better understand why this happens and how to monitor care over time.
Aurora, ColoradoAges 18–45 - NCT07667985Recruiting
Cognitive Reserve and Recovery from Fatigue in Older Adults
This study looks at how life experiences and education (cognitive reserve) help older adults bounce back from mental fatigue. Researchers want to find out if higher cognitive reserve leads to faster recovery after tiredness, which could improve quality of life.
Uşak, UşakAges 65–90 - NCT02855827Recruiting
Monitoring patients who may receive ovarian tissue back
This study follows people who have saved their own ovarian tissue (cryopreserved tissue) and may receive it back to try to restore ovarian function. It’s mainly for people with premature ovarian insufficiency and plans for tissue autograft, with monitoring for safety and outcomes.
BesançonAges 11–43 - NCT03763864Enrolling by invitation
Testing patient skin cells to check gene-related disease causes
This trial builds lab tests using a patient’s own skin cells to see whether the disease’s underlying gene problem can be shown in the lab. If you have a rare inherited (genetic) disease with no good treatment, this could help researchers find clearer, functional ways to measure the disease and test future therapies.
LilleAges Any age - NCT07108920Recruiting
Balance and Botox for Stiff Knee Gait
This study tests whether botulinum toxin (Botox) injections into the rectus femoris thigh muscle can improve balance and walking in people with a stiff knee gait (a common problem after stroke, brain injury, or multiple sclerosis).
Héricourt, Nord Franche-ComtéAges 18 years+
Hear when a new Functionality trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,577 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.