Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,474 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06676839Recruiting
Testing the ICOPE program to prevent age-related decline
This study tests a program called ICOPE, designed by the World Health Organization, to help older adults stay healthy and independent. It will check if the program can slow down age‐related declines in areas like mobility, memory, and nutrition.
Castres, FranceAges 65 years+ - NCT03909477Recruiting
Study of MRI brain scans in cannabis smokers over time
This study follows people who currently or used to smoke cannabis to see how cannabis use may change certain MRI scan signals in the brain over time. You may help researchers understand the effects of cannabis smoking and how brain imaging changes can be measured safely.
London, OntarioAges 18–85 - NCT06658522RecruitingPhase 4
Sotatercept for right heart function in pulmonary hypertension
This study tests a medicine called sotatercept to see if it can improve how the right side of your heart pumps in people with PAH. It may help you feel better and slow down the disease.
Amsterdam, North HollandAges 18–70 - NCT06666803Recruiting
Personalized profile of pancreatic tumors from biopsy samples
This study will take a close-up look at your pancreatic tumor by using a sample from a biopsy to create a personal profile. The goal is to understand your cancer better and maybe find the best treatment for you.
StrasbourgAges 18 years+ - NCT06657001Enrolling by invitation
Personalized nutrition study for gut health
This study uses information from your gut bacteria (microbiome) to create personalized nutrition advice. It is for people with gut conditions like IBD, IBS, or celiac disease, as well as healthy volunteers.
Rochester, MinnesotaAges 18 years+ - NCT06663891Recruiting
MRI study of anergic depression in older adults
This study uses MRI brain scans to look for differences between people whose anergic depression started before age 60 and those whose depression began later in life (after 60). It aims to help understand the root causes of this specific type of depression in older adults.
Strasbourg, Grand EstAges 60–90 - NCT06662955Recruiting
Exercise with sound cues after ACL reconstruction
This study tests if adding sounds (like a metronome beat) to your rehab exercises helps your leg muscles work better after ACL reconstruction. It is for athletes who had their ACL surgery within the past 2 weeks and are ready to start moving.
Salaya, Changwat Nakhon PathomAges 18–35 - NCT06658483Enrolling by invitation
Hand Scleroderma Experience Survey for People With Systemic Sclerosis
This study is testing a new scale to measure what it's like to live with hand problems caused by systemic sclerosis (scleroderma). By answering questions about your daily hand function, you can help doctors better understand your experience and improve care.
Malatya, MalatyaAges 18 years+ - NCT06667427Recruiting
Nerve transfer for facial paralysis in cancer patients
This study tests whether nerve transfer surgery can improve facial movement and quality of life in cancer patients with facial paralysis. Participants either receive the nerve transfer or are part of a control group that had past facial surgery without nerve repair.
Houston, TexasAges 18 years+ - NCT05847426Recruiting
Testing early hearing support using brain scans in babies
This study helps improve early hearing care by using a simple brain scan test (fNIRS) in babies with permanent hearing loss. It compares different early intervention approaches and aims to find better ways to support hearing development early on.
East Melbourne, VictoriaAges 24 years+ - NCT06652347Recruiting
Older adults' views on geriatric tests for cancer treatment planning
This study asks adults aged 65 and older about their views on geriatric and functional assessments to help plan cancer treatment. It tests whether these assessments are acceptable and useful to patients.
Philadelphia, PennsylvaniaAges 65 years+ - NCT06655441RecruitingPhase 4
Trehalose eye drops for dry eye disease
This study tests if a special sugar-based eye drop called trehalose can improve the protective layer of the eye in people with moderate to severe dry eye. It might help strengthen the cornea and reduce discomfort.
Fullerton, CaliforniaAges 18 years+ - NCT06641271Enrolling by invitation
Vagus nerve stimulation with hand exercises for MS
This study tests if vagus nerve stimulation (a mild electrical pulse on the ear) combined with hand exercises can help repair the protective coating of your nerves and improve hand function in multiple sclerosis.
Aurora, ColoradoAges 18–70 - NCT06636786RecruitingPhase 2
Medication to reduce stress symptoms after a car accident
This study tests whether a medication placed under the tongue can help prevent or reduce stress-related symptoms, like anxiety or post-traumatic stress, after a motor vehicle crash. It may help you feel better in the weeks following the accident.
Birmingham, AlabamaAges 18–55 - NCT06640894Recruiting
Power2Walk: strength training for kids with cerebral palsy
This study tests a type of strength training called functional power training for children with cerebral palsy. The goal is to see if it helps kids be more active and take part in daily activities.
Emmen, DrentheAges 4–12 - NCT06635863Enrolling by invitationPhase 4
Steroids versus standard heart medications for heart inflammation
This study compares two treatment strategies for people with unexplained heart failure and irregular heartbeats caused by inflammation: one group gets standard heart medications plus an immune-suppressing steroid (prednisone), and the other gets standard medications alone. Doctors want to see whether adding steroids helps improve heart function and control dangerous heart rhythms.
Phoenix, ArizonaAges 18 years+ - NCT05780021Recruiting
Support program for long-term low back pain after rehab
This trial tests whether a structured motivational support program can help people with long-term low back pain after they finish a rehab program. It may help you stay motivated and improve your day-to-day progress after treatment.
ParisAges 18 years+ - NCT05762952RecruitingPhase 1
Dapagliflozin study for heart micro-blood-flow symptoms in women
This early-phase study tests whether dapagliflozin can improve tiny blood-vessel function in women who have heart-ache-like symptoms but no major blockage on heart scans. If it works, it may help symptoms related to “microvascular” heart circulation problems.
Charlottesville, VirginiaAges 18–99 - NCT06554340Recruiting
Exercise study for multiple sclerosis with high blood pressure
This study tests if exercise can improve blood vessel health and daily function in people with multiple sclerosis (MS) who also have high blood pressure. It may help you move better and feel better.
Boston, MassachusettsAges 18 years+ - NCT06627543Enrolling by invitation
Enzyme replacement therapy for heart health in Gaucher type 3
This study looks at how enzyme replacement therapy affects heart function in children with Gaucher disease type 3. It aims to see if the therapy helps keep the heart healthy.
AsyutAges Any age - NCT06620835RecruitingPhase 2
Optimizing local treatments for ALK-positive lung cancer on brigatinib
This trial is for people with advanced ALK-positive lung cancer who are already taking the targeted therapy brigatinib and have a few remaining spots of cancer. It tests whether adding local treatments (like surgery, focused radiation, or ablation) to the remaining spots can improve outcomes.
BrestAges 18 years+ - NCT06627283Recruiting
Does breathing muscle training help tongue muscles?
This trial tests whether training the muscles you use to breathe can also improve your tongue muscle function. It looks for healthy adults between 18 and 65 who can follow instructions in French or Dutch.
LeuvenAges 18–65 - NCT06623630RecruitingPhase 1
Carvykti with special radiation and chemo for kidney patients
This trial tests adding total body radiation and a chemotherapy drug (cyclophosphamide) before the standard Carvykti cell therapy for multiple myeloma patients who have kidney problems. The goal is to see if this approach is safe and effective for people with reduced kidney function.
St Louis, MissouriAges 18 years+ - NCT06629428RecruitingEarly Phase 1
Study of ublituximab for walking and movement in multiple sclerosis
This trial tests if ublituximab can improve walking and other motor skills in people with active relapsing MS. You must be able to walk at least 25 feet and stand 30 seconds on your own.
Atlanta, GeorgiaAges 18–55
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,474 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.