Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,474 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06710418Recruiting
Comparing two red blood cell transfusion thresholds for people with high-grade myeloid neoplasms, AML or B-ALL
This study compares two different strategies for when to give red blood cell transfusions to people receiving intensive chemotherapy or stem cell transplant for high-grade myeloid neoplasms, AML or B-ALL. The goal is to see which approach better improves quality of life and daily function.
Seattle, WashingtonAges 18 years+ - NCT06705816Recruiting
Cognitive function in Rett syndrome during trofinetide treatment
This study looks at how trofinetide (a medicine for Rett syndrome) affects thinking and memory in people with Rett syndrome. It will follow participants who are starting this treatment through a specific clinic.
Minneapolis, MinnesotaAges 18–99 - NCT06694272Recruiting
Visual function tests for early age-related macular degeneration
This study looks at how well the eyes function in people with early or intermediate age-related macular degeneration (AMD). It uses imaging and vision tests to help doctors better understand the condition.
ParisAges 18 years+ - NCT06697314Recruiting
Clot removal for acute pulmonary embolism with heart strain
This study tests a new device (AlphaVac) that removes blood clots from the lungs using a thin tube inserted through a vein. It may be an option for people with acute pulmonary embolism who have signs of heart strain or low blood pressure.
PoznanAges 18 years+ - NCT06703736Recruiting
Understanding leg function in multiple osteochondromas
This study aims to understand how multiple osteochondromas (bony growths that can form near joints) affect walking and leg function. It compares people with the condition to healthy volunteers, using motion analysis and imaging.
BolognaAges 6–40 - NCT06704074Recruiting
Virtual Reality Training for Arm Recovery After Stroke
This trial tests whether virtual reality (VR) games and tasks can help improve arm and hand movement after a stroke. It is for people who had a first stroke 1 to 6 months ago and have some arm weakness but can sit up for 30 minutes.
Jinan, ShangdongAges 18–80 - NCT06699030Recruiting
Diet therapy to pass tiny gallstones
This trial tests whether a special diet can help pass tiny gallstones (smaller than 2 mm) out of your gallbladder without surgery. It might be a good option if you have very small stones and want to avoid more invasive treatments.
Lanzhou, GansuAges 18–70 - NCT06701422Recruiting
Neck Spinal Cord Stimulation for Recovery After Surgery
This study tests if electrical stimulation of the spinal cord in the neck can help you recover function after cervical spine surgery. It is for people who need neck surgery and do not already have a stimulator device in their neck or chest.
New York, New YorkAges 18 years+ - NCT06694519Recruiting
Radiofrequency and exercise for pelvic floor issues after breast cancer
This trial tests whether radiofrequency therapy combined with exercise can help with pelvic floor problems like pain, urgency, or incontinence that some women have after breast cancer treatment.
Elche, Spain / ValenciaAges 18 years+ - NCT06700187Recruiting
Does reducing sitting time improve thinking?
This study looks at whether taking short breaks from sitting can help your brain work better. You will visit a lab 4 times and will be asked to sit or take short breaks while your thinking is tested.
MaastrichtAges 18–35 - NCT06693674RecruitingPhase 3
Sacubitril-valsartan for heart health in congenital heart disease
This trial tests if a drug called sacubitril-valsartan can improve heart structure and function in adults with congenital heart disease. You will take the drug and have heart imaging to see changes.
Rochester, MinnesotaAges 18 years+ - NCT06688916Recruiting
Body awareness after spinal cord injury
This study examines how people with spinal cord injury experience their body and sense of self. You will answer questionnaires and may have an MRI scan of your brain while parts of your body are touched, to see how your brain reacts.
Nottwil, Canton of LucerneAges 18–65 - NCT06682741Enrolling by invitation
Comparing exercise programs for brain health in women
This study tests whether different types of exercise training can improve thinking and memory in women. It may help find the best workout for keeping your mind sharp.
Poznan, PolandAges 50 years+ - NCT06690684Enrolling by invitation
Finding new blood markers for heart disease
This study is looking for people who have had a heart attack or have heart failure to discover new markers in your blood that could help doctors better understand and treat heart disease. By collecting samples and health data, researchers hope to find clues that improve care for future patients.
Shanghai, Jing 'an DistrictAges 30 years+ - NCT06682481Recruiting
Pancreas-Liver Communication in Teens with Obesity
This study looks at how the pancreas and liver talk to each other in teens with obesity. It may help understand why some teens develop diabetes or fatty liver.
Geneva, Canton of GenevaAges 12–16 - NCT06687564Recruiting
Study of ACTG2 gene changes in children with intestinal blockage
This study looks at how changes (mutations) in a gene called ACTG2 affect the muscles that move food through the gut in children and adults with a rare condition called pediatric intestinal pseudo-obstruction (PIPO). It may help researchers understand the condition better and find new ways to help patients.
MontpellierAges 4 years+ - NCT06692686Recruiting
Testing ankle braces to improve walking after stroke
This trial is studying how different types of ankle braces (AFOs) affect walking ability in people who have had a stroke. It may help find the best brace to improve mobility.
Downey, CaliforniaAges 18 years+ - NCT05982730Recruiting
Segway training for balance and thinking in Parkinson's
This study tests whether practicing balance on a Segway can improve walking and thinking for people with moderate Parkinson's. You will train on a Segway while getting special sensory cues, and researchers will see if it helps your motor skills and cognitive function.
Dallas, TexasAges 50–85 - NCT06415721Recruiting
TMS guided by brain scans for alcohol use disorder
This study uses a brain stimulation technique called TMS combined with MRI scans to treat alcohol use disorder. It aims to see if targeting specific brain connections can help reduce drinking.
Palo Alto, CaliforniaAges 25–75 - NCT05482022Recruiting
Test speaking valve effects for people with tracheostomy and brain injury
This study checks whether a speaking valve changes breathing, swallowing, and voice in people who have a tracheostomy after a brain injury. It may help doctors find safer ways to improve communication and function for people who are in a minimal conscious or unresponsive state.
RaananaAges 18 years+ - NCT06675955RecruitingPhase 3
Extension study to keep taking ocrelizumab for multiple sclerosis
This extension study continues treatment with ocrelizumab for people with multiple sclerosis who are already taking it as part of a parent trial, to see how MS affects physical function over a longer time. It helps ensure you can keep receiving ocrelizumab even if it's not available where you live.
Amiens Cedex1Ages 18 years+ - NCT06672952Recruiting
Citrus compound for exercise, blood flow, and stress in overweight adults
This study looks at whether a natural citrus compound called glucosyl-hesperidin (CitraPeak) can boost your exercise performance, improve blood flow, reduce stress, and sharpen thinking. Researchers want to see if it works differently for people who are moderately overweight or mildly obese.
Saint Charles, MissouriAges 18–50 - NCT06669494Enrolling by invitation
Study on ICU muscle weakness detection and monitoring
This study aims to find better ways to detect and track muscle weakness that can happen during an ICU stay. If you or your loved one is in the ICU, this research could help improve early diagnosis and care.
Seoul, SeoulAges 18 years+ - NCT06677515Recruiting
Using VR to improve social skills in people with substance use and mental health issues
This study tests whether virtual reality (VR) training can help people with substance use and mental health disorders improve their social functioning. If you are getting treatment for substance use and can attend VR sessions twice a week for 5 weeks, you may be able to join.
BrumunddalAges 18–70
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,474 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.