Clinical trials
Genetics clinical trials
Below are recruiting genetics clinical trials, each written for real people, not researchers. We’re tracking 696 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03412877RecruitingPhase 2
Personalized immune-cell therapy for advanced metastatic cancers
This trial tests a personalized cell therapy made from your own immune cells, changed to recognize “neoantigens” on cancer cells. It’s designed for people with metastatic (advanced spread) solid cancers or certain other cancers who have tried standard treatments but cancer is still growing.
Bethesda, MarylandAges 18–72 - NCT03305835Recruiting
Genetic testing for inherited kidney stone causes
This study uses genetic testing to look for inherited (“monogenic”) reasons some people get kidney stones. It may help explain the cause of stones and calcium-related problems, which can guide future care for you or your family.
Rochester, MinnesotaAges Any age - NCT03301038RecruitingPhase 2
Rifampin for high blood calcium
This study tests if rifampin, a medicine usually used for infections, can lower high calcium levels in people with a rare genetic condition affecting vitamin D. It might help reduce symptoms like kidney stones or bone pain.
Philadelphia, PennsylvaniaAges 6 months–70 years - NCT03310879RecruitingPhase 2
Abemaciclib for advanced tumors with cyclin or CDK4/6 gene changes
This Phase 2 study tests abemaciclib, a targeted cancer medicine, in people with advanced solid tumors that have specific gene changes related to cyclin D or CDK4/6. The goal is to see how well it controls tumors when standard treatments don’t work or aren’t available.
Boston, MassachusettsAges 18 years+ - NCT03294460RecruitingPhase 1
Genetic study of smoking and alcohol response in healthy adults
This Phase 1 study tests whether certain genes linked to nicotine receptors affect how people feel and respond to alcohol. It also compares alcohol responses in smokers versus non-smokers using brain imaging (MRI) and alcohol-earning/reward tasks, aiming to better understand why some people may crave alcohol more than others.
Bethesda, MarylandAges 21–60 - NCT03275610Enrolling by invitation
Genetic study in people with past lung blood clots after knee or hip surgery
This study looks at genetic (inherited DNA) markers in people who have had a lung blood clot (pulmonary embolism) after having a hip or knee replacement. The goal is to understand why blood clots may happen again and help improve future risk prediction and care.
Los Angeles, CaliforniaAges 18–70 - NCT03029325Recruiting
Boston lung cancer genetic study
This study looks at tissue samples from people with lung cancer to learn more about the genes and molecules that cause it. By participating, you may help doctors better understand lung cancer and improve future treatments.
Boston, MassachusettsAges 18 years+ - NCT03056794Recruiting
Study of genetic and natural history of PDC deficiency
This study looks at how pyruvate dehydrogenase complex (PDC) deficiency affects people over time and what genes are involved. It mainly helps by building genetic and health data, which may improve future care and understanding of the condition.
Pittsburgh, PennsylvaniaAges Any age - NCT03094026Recruiting
Practice cognitive training after a transplant
This study tests whether a structured cognitive training program can help people think and remember better after an allogeneic stem cell transplant. It may also explore how people feel about genetics and genetic testing.
Birmingham, AlabamaAges 21 years+ - NCT03291392Recruiting
CUHK stroke biobank for blood, fluid, and tissue samples
This study builds a research bank using samples from people with stroke, their family members, and some people without narrowing in their blood vessels. Your samples help researchers study stroke and related brain and vessel changes.
Hong KongAges 18 years+ - NCT03054584Recruiting
Study the genetics behind common skin moles
This study looks at why some people develop melanocytic nevi (common skin moles) by examining genetic factors. It may help researchers understand the causes of moles and could guide future skin health research.
Sacramento, CaliforniaAges 18 years+ - NCT03059420Recruiting
Genetic study of strabismus and certain birth eye-movement disorders
This study looks for genetic (inherited DNA) causes of strabismus (eyes that don’t line up) and certain birth conditions that affect eye movement and brainstem/cranial nerves. Your participation may help researchers better understand these conditions and guide future testing and care.
Boston, MassachusettsAges 1 day+ - NCT03087253Recruiting
Study of what causes and affects lipodystrophy
This study observes people with lipodystrophy to better understand how the condition develops and affects the body over time. It may help researchers learn who is most affected and guide future treatments.
Bethesda, MarylandAges Any age - NCT03062085Recruiting
Study for people with cataracts in Shanghai
This study looks at people who have been diagnosed with cataracts. It checks whether participants can safely and reliably complete eye examinations that the study needs.
Shanghai, Shanghai MunicipalityAges 20–100 - NCT02890641Recruiting
Study of brain signals and genes in hard-to-treat epilepsy
This study looks at genetic factors and brain electrical activity in children whose seizures are difficult to control with standard medicines. It also involves exams like MRI and possibly procedures under anesthesia, to better understand seizure causes and help future care.
ParisAges 3 months–25 years - NCT03000244Recruiting
Long-term follow-up after stem cell or gene therapy
This study checks how people do long-term after stem cell transplant, cellular therapy, or gene therapy. It may help doctors track longer-term health effects and recovery and improve future care.
Bethesda, MarylandAges 4–120 - NCT02692885Recruiting
Study body fat tissue to learn how it affects metabolism
This study looks at samples of body fat to understand what controls metabolism (how your body uses energy). You may be asked for a fat tissue sample during surgery or through a special biopsy scan, depending on your situation.
Bethesda, MarylandAges 18–90 - NCT02829619Recruiting
Eating at Set Times to Help with Weight Loss
This study looks at whether changing when you eat, along with looking at your genes, can help people lose weight. It’s mainly for adults who are above a healthy weight range and don’t have certain health conditions or medicines.
Murcia, MurciaAges 18 years+ - NCT02747888Recruiting
Study of inherited risk for thyroid cancer
This study looks at whether thyroid cancer or thyroid lumps can run in families due to inherited (genetic) risk. It may help researchers better identify who is at higher risk and guide future screening or prevention.
Boston, MassachusettsAges Any age - NCT02878408Recruiting
Study of immune and genetics factors in bipolar or schizophrenia
This study looks at how the immune system, genetics, inflammation, and past exposures may relate to bipolar disorder or schizophrenia. It may help researchers understand the cause and find better ways to support people with these conditions.
Créteil, FranceAges 16 years+ - NCT02720679Recruiting
Study genetics behind blood disorders in children and families
This study looks at genetic (DNA) factors that may contribute to certain blood disorders. You may be invited if you or a close family member is receiving care for a blood condition like MDS or MPN, and the study also includes related relatives.
Memphis, TennesseeAges Any age - NCT02775461Recruiting
Registry for people at high risk for pancreatic cancer
This study is a registry (a way to track health over time) for people with a strong family history or certain inherited genetic risks for pancreatic cancer. It may help doctors learn how best to monitor and protect high-risk people, and to see who benefits most from follow-up.
New York, New YorkAges 18 years+ - NCT02927158Recruiting
Genetic testing study for Amish and Mennonite community members
This study uses genetic testing to learn more about the causes of health conditions in Amish and Mennonite people. It may help researchers understand patterns in this community and improve future care.
Pittsburgh, PennsylvaniaAges Up to 100 years - NCT02958462Recruiting
Clinic study for early blood or bone marrow warning signs
This study follows people who may have early, unclear blood count problems or certain genetic/immune patterns that can later lead to bone marrow failure or blood cancers. It may help doctors better understand risks over time and guide earlier care.
Scottsdale, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for genetics?
- Yes. Clin2 currently lists 696 recruiting genetics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genetics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genetics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.