Clinical trials
Glioblastoma clinical trials
Below are recruiting glioblastoma clinical trials, each written for real people, not researchers. We’re tracking 315 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07387666RecruitingEarly Phase 1
Imaging a common drug in glioblastoma
This trial uses a special imaging technique to see how the drug Acetadote (often used for acetaminophen overdose) behaves in glioblastoma tumors. It may help doctors learn more about the tumor and could guide future treatments.
Dallas, TexasAges 18 years+ - NCT07375992Recruiting
Music therapy for newly diagnosed glioblastoma
This trial tests whether attending virtual music therapy sessions can help people with newly diagnosed glioblastoma feel better after chemoradiation. It aims to improve quality of life and emotional well-being.
Baltimore, MarylandAges 18 years+ - NCT07364786RecruitingPhase 2
Testing Salovum for glioblastoma: oxygen and pressure
This trial tests if Salovum, a special egg yolk product, can improve oxygen levels and reduce pressure and inflammation in the brain for people with a suspected glioblastoma. It involves a biopsy before treatment starts.
LundAges 18–75 - NCT07356973RecruitingPhase 2
Irinotecan chemotherapy seeds for glioblastoma
This trial tests a new way to deliver chemotherapy directly into the brain after surgery for glioblastoma. Tiny seeds containing irinotecan are placed in the tumor cavity during surgery, aiming to kill remaining cancer cells while reducing side effects.
BirminghamAges 18 years+ - NCT05565326Recruiting
Testing MR-guided radiation checks for glioblastoma
This study tests how best to measure and track glioblastoma treatment while using MRI (a body scanner) to guide radiation. It may help improve how doctors assess the radiation response during therapy.
Zurich, Canton of ZurichAges 18 years+ - NCT07343986RecruitingPhase 1
Ultrasound and Immunotherapy for Newly Diagnosed Brain Cancer
This trial tests whether a special ultrasound (LIFU) can open the blood-brain barrier to help an immunotherapy drug (cetuximab) reach glioblastoma tumors better. It is for people with a specific type of glioblastoma that has not been treated yet and that has a certain protein called EGFR.
Charlottesville, VirginiaAges 18–70 - NCT05769660RecruitingPhase 1
Study BEY1107 plus temozolomide for recurrent glioblastoma
This Phase 1 study tests the safety and early effectiveness of BEY1107 combined with temozolomide in adults whose glioblastoma has come back or kept growing after standard treatment. If you qualify, you may be able to receive this combination while the researchers closely monitor side effects and tumor response.
SeoulAges 19 years+ - NCT07318818RecruitingPhase 1/Phase 2
Revised cell therapy for recurrent brain cancer
This trial tests a new cell therapy (P134 cells) for people whose glioblastoma has come back after standard treatments like radiation or chemotherapy. The therapy uses a patient's own immune cells (PBMCs) to target cancer cells that have specific markers (CD44 or CD133). It also requires a small procedure to place a reservoir under the scalp for drug delivery.
BeijingAges 18–70 - NCT05941234Recruiting
Studying stem cells and blood patterns in glioblastoma
This study analyzes tissue and health-related biological data from people with glioblastoma to learn what’s happening in the tumor. The results may help improve future ways to understand and treat glioblastoma using advanced computer analysis.
RomeAges 18 years+ - NCT07297212RecruitingPhase 2
Testing the drug pumitamig for recurrent glioblastoma
This trial tests an investigational drug called pumitamig (also known as BNT327) in people whose glioblastoma has come back after standard treatment with radiation and temozolomide. The goal is to see if the drug is safe and whether it can help slow or stop tumor growth.
BeijingAges 18–75 - NCT07284069RecruitingEarly Phase 1
Senicapoc and perampanel for newly diagnosed glioblastoma
This trial tests two drugs, senicapoc and perampanel, added to standard treatment for people with newly diagnosed glioblastoma. The goal is to see if they can help slow tumor growth or improve outcomes.
Aarhus, DenmarkAges 18 years+ - NCT07284628RecruitingPhase 2
Vortioxetine for newly diagnosed glioblastoma
This trial tests whether the antidepressant vortioxetine can help people with newly diagnosed glioblastoma when added to standard radiation and chemotherapy. The goal is to see if it improves mood, quality of life, and possibly treatment outcomes.
ZurichAges 18 years+ - NCT07274397Recruiting
Early brain scan study after glioblastoma surgery
This study tests whether it is safe and possible to do a special brain scan (nuclear imaging) within the first 3 days after surgery for glioblastoma. It may help doctors understand how well the tumor was removed and guide future treatments.
CréteilAges 18 years+ - NCT07263438RecruitingPhase 2
Trimipramine, atezolizumab, and bevacizumab for recurrent glioblastoma
This trial tests a combination of three drugs—trimipramine (an antidepressant), atezolizumab (an immunotherapy), and bevacizumab (a targeted therapy)—in people whose glioblastoma has come back after initial treatment. The goal is to see if this mix can help shrink the tumor or slow its growth.
Basel, BaselAges 18 years+ - NCT07225621RecruitingPhase 2
Light and sound therapy for newly diagnosed glioblastoma
This trial tests a new approach that uses a light-sensitive drug and low-intensity ultrasound to make standard chemotherapy more effective for glioblastoma. If you have completed initial treatment with radiation and temozolomide without the tumor growing, you may be eligible.
Boston, MassachusettsAges 18–80 - NCT07193654RecruitingPhase 2
Combined stupp therapy and spinal chemo for advanced glioblastoma
This trial tests adding a chemotherapy drug (thiotepa) directly into the spinal fluid for people with a newly diagnosed glioblastoma that has spread to the brain's lining or ventricles. It aims to see if this extra treatment can help control the cancer.
Hangzhou, ZhejiangAges 18–75 - NCT07173829Recruiting
Study of why glioblastoma comes back
This trial collects tumor samples to study what causes glioblastoma to return. It may help scientists find better treatments.
BordeauxAges 18 years+ - NCT07145112RecruitingPhase 1
Laser therapy and lomustine for recurrent glioblastoma
This trial combines laser heat therapy (LITT) with the chemotherapy drug lomustine (CCNU) for people whose glioblastoma has returned. It aims to see if the combination is safe and effective.
Sacramento, CaliforniaAges 18 years+ - NCT07145047RecruitingPhase 1/Phase 2
Oncolytic virus trial for recurrent glioblastoma
This trial tests a virus-based treatment for glioblastoma that has come back after standard therapies. The virus is designed to infect and destroy cancer cells while leaving healthy cells alone.
Mianyang, SichuanAges 18–70 - NCT06598787RecruitingPhase 2
Study of a new drug for recurrent glioblastoma
This trial tests a new drug called BL-B01D1 for people whose glioblastoma has come back after standard treatment. The goal is to see if the drug can help control the tumor.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07134842RecruitingPhase 1
Immunotherapy before standard brain cancer treatment
This trial tests giving the immunotherapy drug ipilimumab before the usual treatment for newly diagnosed glioblastoma (a type of brain cancer). The goal is to see if this approach is safe and possible, and whether it might help the immune system fight the tumor better.
London, Greater LondonAges 18 years+ - NCT07130149Enrolling by invitationPhase 2
Sonodynamic therapy plus chemoradiation for glioblastoma
This trial combines a new therapy (sonodynamic therapy) with standard radiation and chemotherapy for glioblastoma. It aims to see if this approach is safe and how well it works for people who have just been diagnosed and had surgery.
Zhengzhou, HenanAges Up to 75 years - NCT07121842Recruiting
New MRI scan to track glioblastoma growth during treatment
This study is testing a new type of MRI called APTw-CEST to see if it can better detect tumor progression in people with glioblastoma. It may help doctors monitor your tumor more accurately during radiation or chemoradiation therapy.
AmsterdamAges 18 years+ - NCT07119294Recruiting
FAPI PET/MR imaging for glioblastoma
This study uses a special PET/MR scan to look at certain cells called cancer-associated fibroblasts in glioblastoma brain tumors. It aims to see if this imaging approach can better detect tumors or their recurrence, helping guide treatment decisions.
BrusselsAges 18 years+
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Common questions
- Are there clinical trials for glioblastoma?
- Yes. Clin2 currently lists 315 recruiting glioblastoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a glioblastoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a glioblastoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.