Clinical trials
Gut Microbiome clinical trials
Below are recruiting gut microbiome clinical trials, each written for real people, not researchers. We’re tracking 141 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06100211Recruiting
HIV, gut health, and switching HIV meds study
This study looks at how changing your HIV medication affects the bacteria in your gut. You'll provide two stool samples so researchers can see what changes happen.
Manchester, Greater ManchesterAges 18 years+ - NCT06831539RecruitingPhase 1
How bowel prep affects gut bacteria recovery
This study looks at how the bowel preparation medicine (PEG) used before a colonoscopy affects the bacteria living in your gut and how well they recover afterward. Healthy volunteers will take the bowel prep and provide stool samples to help researchers understand this process.
Montreal, QuebecAges 18–70 - NCT06545123Recruiting
How different exercises affect gut health in older adults with muscle loss
This study looks at how different types of exercise can change the bacteria in your gut for older adults who have muscle loss (sarcopenia). You will be assigned to one of two exercise programs to see which one helps your muscles and gut health the most.
PortoAges 60 years+ - NCT07351175Recruiting
Can a special cheese lower cholesterol by changing gut bacteria?
This study tests whether eating a type of aged cheese can help lower cholesterol by affecting the good bacteria in your gut. It is for people who regularly eat cheese, have slightly high cholesterol, and are generally healthy.
ReadingAges 18–65 - NCT06495190Recruiting
Blueberries, exercise, and memory in older adults
This study tests whether eating blueberries and doing regular exercise can help with mild memory decline. You will be assigned to one of four groups (blueberries + walking, blueberries + stretching, or similar combos) for 12 weeks.
Kannapolis, North CarolinaAges 65–85 - NCT07280091Recruiting
Skin and gut bacteria in Netherton syndrome
This study looks at the bacteria on the skin and in the gut of people with Netherton syndrome, a condition that affects the skin barrier and often causes allergies. It also compares these findings to healthy volunteers to understand how the microbiome might be different.
Paris, Île-de-France RegionAges 10 years+ - NCT07259681Recruiting
A study on gut health, pelvic side effects, and ozone therapy
This study looks at the bacteria in your gut (gut microbiome) to see how it is affected by pelvic side effects from cancer treatment, and whether ozone therapy might help. It compares patients who have chronic pelvic side effects and are treated with ozone (cases) to those who do not have these side effects (controls).
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT07225153Recruiting
Goat milk formula vs. undiluted goat milk for infant growth
This trial tests whether a goat milk-based formula helps infants who cannot breastfeed grow as well as those who drink undiluted goat milk. It focuses on babies living in the Matiari District whose families have access to goat milk.
Matiāri, SindhAges 2 months–2 months - NCT06929364Recruiting
Probiotics for endometriosis – a crossover trial
This study tests whether taking a probiotic supplement can help with endometriosis symptoms. It's for women 35 or younger with moderate to severe endometriosis, and involves a crossover design where everyone gets both the probiotic and a placebo at different times.
ZagrebAges Up to 35 years - NCT07173062Recruiting
Algae supplement for heart health and gut bacteria
This study tests whether a supplement made from algae can help improve markers of heart health and affect the bacteria in your gut. It is for people age 50 and older who already have a condition like heart disease, kidney disease, or diabetes.
PortoAges 50 years+ - NCT07162337Recruiting
Diet education to lower colon cancer risk after polyp removal
This study tests whether a diet education program can change the balance of gut bacteria and bile acids to lower the risk of colorectal cancer in people who have had polyps removed.
Boston, MassachusettsAges 18–80 - NCT07093346Recruiting
Pectin supplement for fatty liver disease
This study tests whether a pectin supplement (a fiber found in fruits) can reduce inflammation and improve liver and metabolic health in people with fatty liver disease (MASLD). You might be eligible if you have MASLD, a healthy weight range, and can avoid certain medications and foods.
Nottingham, United KingdomAges 18 years+ - NCT06959043Recruiting
Diet and exercise for type 2 diabetes
This study tests if a plant-based diet and exercise program can improve blood sugar control in people with type 2 diabetes. Participants will live in a hospital for 4 weeks to follow the program closely.
São Paulo, São PauloAges 45–70 - NCT07069751Recruiting
Plant-based diet study for smoldering myeloma
This study tests whether a high-fiber plant-based diet can improve gut health in people with smoldering multiple myeloma. It aims to see if diet changes can slow or prevent the disease from progressing.
Milan, MilanoAges 18–75 - NCT06986265Recruiting
Kidney failure, weight loss, and gut health study
This study looks at how gut bacteria might affect weight loss in people with kidney failure who are on dialysis. It may help find new ways to prevent or treat weight loss in this condition.
BrusselsAges 18 years+ - NCT07052409Enrolling by invitation
Protecting HIV-exposed infants from severe infections
This trial studies ways to protect babies who were exposed to HIV before birth but are not infected themselves. It aims to find better interventions to prevent severe infections in these infants.
JohannesburgAges 6 months–45 years - NCT06977113Recruiting
High-fiber fermented foods for breastfeeding moms and babies
This study tests if a diet rich in high-fiber fermented foods for breastfeeding mothers can improve the gut health of their exclusively breastfed infants. It is designed for healthy mothers and babies without chronic conditions or recent antibiotic use.
Glasgow, ScotlandAges 2 months–45 years - NCT06951477Recruiting
Gut health and knee replacement revision study
This study looks at how the bacteria in your gut might affect recovery after a second knee replacement surgery. Researchers want to learn more about the connection between gut health and surgical outcomes.
London, OntarioAges Any age - NCT06448546Recruiting
Gut bacteria in Huntington's disease
This study looks at how gut bacteria are different in people with Huntington's disease who have unusual weight changes. You'll provide stool and blood samples to help researchers understand gut health in HD.
Orlando, FloridaAges 18 years+ - NCT06846138Enrolling by invitation
Herbal supplement to help metformin work better and cause fewer side effects
This study tests a special herbal blend added to metformin to see if it helps reduce stomach problems and improves blood sugar control in people with type 2 diabetes. Researchers want to understand how the herbs affect the bacteria in your gut.
RigaAges 25–80 - NCT06833593Recruiting
Antibiotic combinations for enterococcus blood infection
This study looks at whether using two or more antibiotics together works better than one alone for a specific type of blood infection caused by Enterococcus faecalis bacteria. The goal is to find the safest and most effective way to treat this infection and improve outcomes for patients.
Bologna, BolognaAges 18 years+ - NCT06799351RecruitingPhase 2/Phase 3
Gut bacteria and nerve pain after chemo
This study looks at how bacteria in your gut (microbiome) might be linked to nerve pain from chemotherapy. It is for people who are already in the OzoParQT trial and will provide a stool sample to help understand this connection.
Las Palmas, Las PalmasAges 18 years+ - NCT06799481Recruiting
Home-based exercise to help brain tumor survivors with thinking and memory
This study tests whether a virtual home-based exercise program can improve thinking and memory problems caused by brain tumor treatment in teens and young adults. It also looks at how exercise affects gut health.
Atlanta, GeorgiaAges 15–39 - NCT06536881Recruiting
Diet and gut health during breast cancer chemo
This study looks at how changing your diet during chemotherapy affects side effects and your body's energy use. It involves providing stool samples to study gut bacteria.
Washington D.C., District of ColumbiaAges 18 years+
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Common questions
- Are there clinical trials for gut microbiome?
- Yes. Clin2 currently lists 141 recruiting gut microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gut microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gut microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.