Clinical trials
Gut Microbiome clinical trials
Below are recruiting gut microbiome clinical trials, each written for real people, not researchers. We’re tracking 139 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06710574RecruitingPhase 4
Probiotics for sleep problems in Parkinson's disease
This study tests whether taking probiotics can improve REM sleep behavior disorder (RBD) in people with Parkinson's disease. You will receive either a probiotic supplement or a placebo, and researchers will use brain scans to see how it affects your symptoms.
BeijingAges 40–85 - NCT06799351RecruitingPhase 2/Phase 3
Gut bacteria and nerve pain after chemo
This study looks at how bacteria in your gut (microbiome) might be linked to nerve pain from chemotherapy. It is for people who are already in the OzoParQT trial and will provide a stool sample to help understand this connection.
Las Palmas, Las PalmasAges 18 years+ - NCT06799481Recruiting
Home-based exercise to help brain tumor survivors with thinking and memory
This study tests whether a virtual home-based exercise program can improve thinking and memory problems caused by brain tumor treatment in teens and young adults. It also looks at how exercise affects gut health.
Atlanta, GeorgiaAges 15–39 - NCT06803706Recruiting
Gut bacteria changes during smoking quit attempt
This study looks at how quitting smoking changes your body's gut bacteria and metabolism. It is for people with a substance use disorder who want to stop smoking.
FehringAges 18 years+ - NCT06831539RecruitingPhase 1
How bowel prep affects gut bacteria recovery
This study looks at how the bowel preparation medicine (PEG) used before a colonoscopy affects the bacteria living in your gut and how well they recover afterward. Healthy volunteers will take the bowel prep and provide stool samples to help researchers understand this process.
Montreal, QuebecAges 18–70 - NCT06929364Recruiting
Probiotics for endometriosis – a crossover trial
This study tests whether taking a probiotic supplement can help with endometriosis symptoms. It's for women 35 or younger with moderate to severe endometriosis, and involves a crossover design where everyone gets both the probiotic and a placebo at different times.
ZagrebAges Up to 35 years - NCT06959043Recruiting
Diet and exercise for type 2 diabetes
This study tests if a plant-based diet and exercise program can improve blood sugar control in people with type 2 diabetes. Participants will live in a hospital for 4 weeks to follow the program closely.
São Paulo, São PauloAges 45–70 - NCT06977113Recruiting
High-fiber fermented foods for breastfeeding moms and babies
This study tests if a diet rich in high-fiber fermented foods for breastfeeding mothers can improve the gut health of their exclusively breastfed infants. It is designed for healthy mothers and babies without chronic conditions or recent antibiotic use.
Glasgow, ScotlandAges 2 months–45 years - NCT06986265Recruiting
Kidney failure, weight loss, and gut health study
This study looks at how gut bacteria might affect weight loss in people with kidney failure who are on dialysis. It may help find new ways to prevent or treat weight loss in this condition.
BrusselsAges 18 years+ - NCT07069751Recruiting
Plant-based diet study for smoldering myeloma
This study tests whether a high-fiber plant-based diet can improve gut health in people with smoldering multiple myeloma. It aims to see if diet changes can slow or prevent the disease from progressing.
Milan, MilanoAges 18–75 - NCT07093346Recruiting
Pectin supplement for fatty liver disease
This study tests whether a pectin supplement (a fiber found in fruits) can reduce inflammation and improve liver and metabolic health in people with fatty liver disease (MASLD). You might be eligible if you have MASLD, a healthy weight range, and can avoid certain medications and foods.
NottinghamAges 18 years+ - NCT07162337Recruiting
Diet education to lower colon cancer risk after polyp removal
This study tests whether a diet education program can change the balance of gut bacteria and bile acids to lower the risk of colorectal cancer in people who have had polyps removed.
Boston, MassachusettsAges 18–80 - NCT07173062Recruiting
Algae supplement for heart health and gut bacteria
This study tests whether a supplement made from algae can help improve markers of heart health and affect the bacteria in your gut. It is for people age 50 and older who already have a condition like heart disease, kidney disease, or diabetes.
PortoAges 50 years+ - NCT07225153Recruiting
Goat milk formula vs. undiluted goat milk for infant growth
This trial tests whether a goat milk-based formula helps infants who cannot breastfeed grow as well as those who drink undiluted goat milk. It focuses on babies living in the Matiari District whose families have access to goat milk.
Matiāri, SindhAges 2 months–2 months - NCT07351175Recruiting
Can a special cheese lower cholesterol by changing gut bacteria?
This study tests whether eating a type of aged cheese can help lower cholesterol by affecting the good bacteria in your gut. It is for people who regularly eat cheese, have slightly high cholesterol, and are generally healthy.
ReadingAges 18–65 - NCT07280091Recruiting
Skin and gut bacteria in Netherton syndrome
This study looks at the bacteria on the skin and in the gut of people with Netherton syndrome, a condition that affects the skin barrier and often causes allergies. It also compares these findings to healthy volunteers to understand how the microbiome might be different.
Paris, Île-de-France RegionAges 10 years+ - NCT07477470Recruiting
Fiber supplement for stress and mood
This study tests whether a daily fiber supplement can improve mood, memory, and gut health in stressed adults. It lasts a few weeks and involves questionnaires and samples.
LondonAges 18–50 - NCT07517029Recruiting
Gut Bacteria Study in Post-Infectious IBS
This study looks at how gut bacteria may change in people who developed irritable bowel syndrome (IBS) after a stomach infection. Researchers hope to understand why some people recover completely while others develop ongoing digestive problems.
RomeAges 18 years+ - NCT07636850Recruiting
How almonds affect gut bacteria in children
This study looks at whether eating almonds changes the helpful bacteria in kids' stomachs and intestines. Researchers will give some children almonds to eat and study how it affects their digestive health.
Tallahassee, FloridaAges 6–13 - NCT07650149Recruiting
Genetic and Lifestyle Factors in Weight Management
This study explores how genetics, gut bacteria, and behaviors influence weight gain and obesity. Researchers will examine these factors in adults who are overweight or obese to better understand what drives weight changes.
KrakowAges 18–60 - NCT07515430Enrolling by invitation
Gut Bacteria and Cancer Symptoms in Children With Leukemia
This study looks at how the bacteria living in your child's gut may affect cancer-related symptoms (like nausea, fatigue, or pain) during leukemia treatment. Researchers will collect stool samples and track symptoms to understand this connection better.
Guangzhou, GuangdongAges 5–18 - NCT06846138Enrolling by invitation
Herbal supplement to help metformin work better and cause fewer side effects
This study tests a special herbal blend added to metformin to see if it helps reduce stomach problems and improves blood sugar control in people with type 2 diabetes. Researchers want to understand how the herbs affect the bacteria in your gut.
RigaAges 25–80 - NCT06361524Enrolling by invitation
Gut bacteria study in chronic heart failure
This study looks at the bacteria in your gut (your 'gut microbiome') and how it relates to chronic heart failure. It may help doctors understand why some people with heart failure do better than others and could lead to better treatments in the future.
Stanford, CaliforniaAges 18–75 - NCT04885959Enrolling by invitation
Study how an Asian diet affects gut bacteria and allergy risk in pregnancy
This study looks at whether eating a traditional Asian diet during pregnancy changes gut bacteria and body chemistry in a way that may lower (or change) a baby’s risk of developing allergies. You would follow the diet during pregnancy and be tracked after delivery.
Kota Bharu, KelantanAges 18–40
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Common questions
- Are there clinical trials for gut microbiome?
- Yes. Clin2 currently lists 139 recruiting gut microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gut microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gut microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.