Clinical trials
Gut Microbiota clinical trials
Below are recruiting gut microbiota clinical trials, each written for real people, not researchers. We’re tracking 158 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06527326Recruiting
Gut bacteria and central serous chorioretinopathy study
This study looks at the link between gut bacteria and central serous chorioretinopathy (CSC), a condition where fluid builds up under the retina. It may help us understand why some people get CSC and find better ways to treat it.
Hanzhou, ZhejiangAges Any age - NCT06528041Recruiting
Chicory fiber and gut health study
This study tests whether a natural fiber from chicory root can change and keep changes in your gut bacteria. It may help improve digestion and overall health.
West Lafayette, IndianaAges 18–45 - NCT06539832Recruiting
Gut bacteria and immunity in people with an abnormal blood protein
This study looks at how your gut bacteria (intestinal flora) and immune system relate to a condition called monoclonal gammopathy, where an abnormal protein is found in the blood. The trial will check samples from your blood, plasma, and stool to understand these connections.
Guanzhou, GuangdongAges 45 years+ - NCT06562842Recruiting
Exercise, Gut Health, and Type 2 Diabetes Study
This study looks at how exercise affects gut bacteria in people with type 2 diabetes. It may help explain why physical activity improves diabetes control.
TrikalaAges 45–65 - NCT06585982Recruiting
Synbiotics for MAFLD: gut health and liver fat study
This trial tests whether taking a synbiotic (a mix of helpful bacteria and fiber) can improve insulin levels and reduce inflammation in people with Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD). It may help by changing the balance of bacteria in your gut.
Semarang, SemarangAges 25–55 - NCT06631937Recruiting
How infant feeding affects gut health and immunity
This study looks at how different feeding methods (like breast milk or formula) affect the development of healthy bacteria in a baby's gut and their immune system. It may help us understand what helps babies stay healthy.
AarhusAges birth–4 weeks - NCT06690593Recruiting
Gut Microbiome Study for Healthy Adults Age 45+
This study compares the gut bacteria of healthy adults (age 45+) with those who have a blood condition called monoclonal gammopathy. The goal is to see if gut bacteria patterns differ between the two groups.
Guanzhou, GuangdongAges 45 years+ - NCT06704321Recruiting
Effects of TOTUM-448 on liver fat and heart health
This trial tests a supplement called TOTUM-448 to see if it can reduce liver fat and improve heart health in people with a fatty liver condition (MASLD). If you have excess liver fat and are overweight, this study could help find new ways to manage your condition.
Québec, QuebecAges 18–75 - NCT06714903Recruiting
Gut bacteria and immunotherapy for advanced colon cancer
This study looks at how the bacteria in your gut might affect how well immunotherapy works for advanced colorectal cancer that has spread. It aims to find out if certain gut bacteria can help make treatment more effective.
Changchun, JilinAges 35–75 - NCT06724536Recruiting
Study of gut bacteria and TKIs in chronic myeloid leukemia
This trial looks at how gut bacteria affect the way chronic myeloid leukemia (CML) patients respond to tyrosine kinase inhibitor (TKI) medications. It may help doctors understand why some people have better outcomes than others.
TorinoAges 18 years+ - NCT06828159Recruiting
Can wild blueberries improve joint health?
This study tests whether eating wild blueberries can improve joint health in people with arthritis. You would eat blueberries or a placebo daily for several weeks to see if they help with pain and stiffness.
Oklahoma City, OklahomaAges 40–75 - NCT06867198Recruiting
Peanuts for heart, brain, and gut health
This study tests whether eating peanuts can improve health markers like blood sugar, brain function, and digestion in adults with prediabetes (higher than normal blood sugar levels). You may qualify if you are between 20-59 years old, have prediabetes, and a BMI in the overweight to obese range.
Atlanta, GeorgiaAges 20–59 - NCT06929845Recruiting
Organoid models for liver cancer study
This study uses tumor samples to create lab-grown mini-livers (organoids) to better understand liver cancer. It may help researchers learn more about the disease and develop new treatments.
RomaAges 18 years+ - NCT07009223Recruiting
Lifestyle changes to prevent memory issues in depression
This study tests whether healthy lifestyle changes—like diet, exercise, or stress management—can help prevent memory and thinking problems in people with depression. It aims to find ways to protect your brain health as you age.
BresciaAges 50–80 - NCT07065942Recruiting
Lactulose for gut health in diabetes with constipation
This study tests if a common stool softener called lactulose can improve gut health and metabolism in people with type 2 diabetes and long-term constipation. It aims to see if changing gut bacteria can help both digestion and blood sugar control.
BeijingAges 18–70 - NCT07110311Recruiting
How pet cats affect nose and gut bacteria in cat allergy patients
This study looks at how living with a pet cat might affect the bacteria in your nose and gut if you have dust mite and cat allergies. It could help us understand if cats actually change your allergy symptoms or the balance of bugs in your body.
Nanjing, JiangsuAges 18–65 - NCT07182500RecruitingPhase 2
Can probiotics protect your gut while traveling?
This trial tests whether taking a probiotic supplement can help keep your gut bacteria healthy during a short trip abroad. It's a good fit if you are generally healthy and planning a vacation or business trip under a week.
Huangpu, Shanghai MunicipalityAges 18–65 - NCT07211321Recruiting
Diet, inflammation, and muscle loss in older adults
This study looks at how diet and gut health relate to muscle loss (sarcopenia) in adults 60 and older. It aims to understand links between inflammation, gut bacteria, and muscle strength so we can find better ways to prevent frailty.
Lanzhou, GansuAges 60 years+ - NCT07229521Recruiting
Nattokinase for heart, gut, sleep, and brain health in metabolic syndrome with sleep issues
This study tests whether a supplement called nattokinase can improve heart health, sleep, thinking, and gut bacteria in people with metabolic syndrome and mild-to-moderate sleep apnea. If you have a larger waist, blood pressure or blood sugar issues, or imbalanced cholesterol, and have been diagnosed with mild or moderate sleep apnea, you may be eligible.
TaipeiAges 18 years+ - NCT07247838Recruiting
Gut bacteria changes in first-time stroke patients
This study looks at how gut bacteria change right after a first-time ischemic stroke. It aims to understand if these changes are linked to recovery or other health factors.
Nantong, JiangsuAges 18 years+ - NCT07252427Recruiting
Gut bacteria in IBD with or without depression
This study looks at how the bacteria in your gut (gut microbiome) may differ between people with IBD who also have depression and those who don't. It aims to help understand the link between gut health and mood.
Jinan, ShandongAges 18 years+ - NCT07264998Recruiting
Gut bacteria study in breast cancer patients on Abemaciclib
This study looks at how gut bacteria changes in people taking Abemaciclib (a breast cancer drug) and whether that relates to diarrhea. It may help find ways to prevent or manage this side effect.
Wuhan, HubeiAges 18–75 - NCT07287306Recruiting
Probiotic study on gut health in healthy adults
This trial tests two probiotics, BLa80 and LRa05, to see how they affect the gut's natural bacteria and related substances. It may help understand how these probiotics support overall health.
Guangzhou, GuangdongAges 18–60 - NCT07300553RecruitingPhase 2
Gut bacteria and energy metabolism in health and IBD
This study looks at how the bacteria living in your gut affect your body's energy use. It includes both healthy volunteers and people with inactive Crohn's disease or ulcerative colitis.
ParisAges 18–50
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Common questions
- Are there clinical trials for gut microbiota?
- Yes. Clin2 currently lists 158 recruiting gut microbiota studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gut microbiota trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gut microbiota trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.