Clinical trials
Gut Microbiota clinical trials
Below are recruiting gut microbiota clinical trials, each written for real people, not researchers. We’re tracking 145 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05000996Recruiting
Gut microbiome study for people having metabolic surgery
This study looks at your gut bacteria (your “microbiome”) around the time of metabolic surgery. It may help researchers understand how surgery affects gut health and related conditions like diabetes, blood pressure, and cholesterol.
Nashville, TennesseeAges 21–65 - NCT05975541Recruiting
Infection risk in obesity and type 2 diabetes
This study looks at how obesity and type 2 diabetes affect your body's ability to fight infections. By joining, you'll help researchers understand why some people with these conditions get more infections, which could lead to better prevention and treatment.
Novara, NovaraAges 18–65 - NCT05319067Recruiting
Gut bacteria study in toddlers on long-term reflux antibiotics
This study compares gut bacteria (microbiome) in toddlers who take an antibiotic to prevent urine infections for vesicoureteral reflux, versus other similar children. It may help researchers understand how long-term antibiotic use and reflux affect gut health and future risk.
MontpellierAges 1–3 - NCT05054361Recruiting
Study gut immunity changes in children with type 1 diabetes
This study looks at how a type of immune cell (MAIT cells) and the gut (microbiota and gut lining) change around the time type 1 diabetes starts in children. It may help researchers understand why type 1 diabetes begins and how the gut and immune system are connected.
AntonyAges 1–15 - NCT04809688Enrolling by invitation
Study how berries affect metabolism and gut bacteria
This study looks at whether eating Saskatoon berries changes how your body uses energy (metabolism) and how your gut bacteria behave. It’s done in healthy people and may help researchers understand how foods could support overall health.
Winnipeg, ManitobaAges 18–75 - NCT04730622Recruiting
Studying muscle and bone changes after a hip fracture
This study looks at how bone health and muscle strength (“osteosarcopenia” — loss of both bone and muscle) change after a hip fracture in older adults. It may help doctors understand who is at higher risk and how to better support recovery after hip surgery.
BolognaAges 65 years+ - NCT02653001Enrolling by invitation
Testing samples in healthy people near Norwich Research Park
This study collects bowel-related samples from healthy people to help researchers test a “colon model” in the lab. You may be eligible if you live or work close by and you don’t have ongoing stomach/bowel conditions or recent major changes.
Norwich, NorfolkAges 18 years+ - NCT07686835RecruitingPhase 2
High-fiber diet to help immunotherapy work better in advanced melanoma
This trial tests if adding extra dietary fiber before and during immunotherapy can change gut bacteria to make the treatment more effective. It is for people with advanced melanoma who are about to start their first immunotherapy.
Nijmegen, GelderlandAges 18 years+ - NCT07313007Recruiting
Gut bacteria chemicals in fatty liver disease
This study looks at whether the natural chemicals made by your gut bacteria from the food you eat could affect liver fat and health. If you have MASLD (a fatty liver condition), researchers want to measure these gut-produced substances to better understand the disease.
Pierre-BéniteAges 18–80 - NCT06546020Recruiting
Haskap berries for gut and metabolic health
This study tests whether a berry called Haskap can improve your gut health and how that might affect your overall health. Researchers are looking for people with and without certain metabolic risk factors to see who benefits most from adding these berries to their diet.
Bozeman, MontanaAges 35–65 - NCT06139224Recruiting
Gut Bacteria and Inflammation in HIV and Heavy Drinking
This study looks at how gut bacteria and inflammation interact in people with both HIV and heavy alcohol use. It aims to find new ways to improve health by understanding these connections.
Chicago, IllinoisAges 45–75 - NCT05646901Recruiting
Study how gut bacteria may affect loss of eating control
This study looks at how gut bacteria and the brain may be involved when people struggle to control eating. It may help researchers understand the body’s signals behind eating control problems.
Girona, GironaAges 30–65 - NCT05996016Recruiting
Gut and vaginal bacteria in HIV-positive women
This study looks at the types of bacteria living in the gut and vagina of women with HIV, including pregnant women. It aims to understand how these bacteria might affect health.
Beijing, Beijing MunicipalityAges 14 years+ - NCT07450443RecruitingPhase 2/Phase 3
Gut health and autism: a study on the gut barrier and bacteria
This trial is looking at the connection between the gut and autism. It tests whether certain gut bacteria and the gut's protective barrier are different in children with autism and gastrointestinal issues. This could help find new ways to improve symptoms.
Milan, MIAges 3–8 - NCT03325855Recruiting
Fecal transplant registry for patients and donors
This study is a national “registry” that collects information from people who get fecal microbiota transplant (a stool-based treatment) and from people who donate stool. It helps researchers understand who receives these treatments and how they do over time.
Phoenix, ArizonaAges Any age - NCT07198984Recruiting
Boosting gut bacteria to improve digestive health
This study tests whether boosting certain gut bacteria can improve your gut health. If you're a healthy adult who exercises regularly or eats a flexitarian diet, this trial may be for you.
Jouy-en-JosasAges 20–80 - NCT06423508Recruiting
Testing stool storage methods and gut bacteria differences
This trial will study how different storage methods affect stool samples for gut bacteria analysis. It aims to understand differences in gut bacteria between people over time. Participation involves providing stool samples.
Vienna, State of ViennaAges 18–70 - NCT05067595RecruitingPhase 1
Fecal transplant and fiber for gut graft-versus-host disease
This study tests whether a fecal microbiota transplant (a procedure that puts healthy donor bacteria into your gut) combined with a dietary fiber supplement can help treat gut graft-versus-host disease, a common complication after a stem cell transplant. It may help reduce diarrhea and other gut symptoms.
Seattle, WashingtonAges 18 years+ - NCT07460856Recruiting
Can Cranberries Improve Your Gut and Metabolic Health?
This study tests if eating cranberries can improve your gut health and metabolism. It’s for people who are overweight and have early signs of metabolic problems, like high blood sugar or high triglycerides.
Québec, QuebecAges 25–70 - NCT03148743Recruiting
Fecal transplant for gut graft-versus-host disease
This study tests whether a fecal transplant (FMT) can help treat gut graft-versus-host disease (gut GVHD), a condition where donated immune cells attack the intestines. If you have gut GVHD and meet age requirements, you may be eligible to receive this treatment in the trial.
Suzhou, JiangsuAges 10–60 - NCT04117321Recruiting
Study of mother-to-baby gut germs and baby health
This study looks at how germs in a mother can be passed to her baby and whether that affects the baby’s health. If you join, your baby (and the other parent or legal guardian) may be asked to share consent so researchers can follow the pregnancy and early life.
Hong Kong, Hong KongAges Any age - NCT06481852RecruitingPhase 1
Gut bacteria transplant for pulmonary arterial hypertension
This trial tests whether a special combination of antibiotics, fecal transplant (gut bacteria from healthy donors), and a fiber supplement can help people with pulmonary arterial hypertension (PAH). It aims to see if improving gut health can improve PAH symptoms and overall well-being.
Minneapolis, MinnesotaAges 18–75 - NCT05024188Recruiting
Gut bacteria and exercise performance study
This study looks at how the bacteria in your gut might affect your physical fitness and exercise ability. You would need to be a regular exerciser and take some antibiotics as part of the study.
RehovotAges 20–55 - NCT04444362Enrolling by invitation
Probacine to protect organs after cardiovascular surgery
This study tests whether a medicine called Probacine can help protect your gut and organs after cardiovascular surgery. If you qualify, you may be asked to take part and follow the study plan to see if complications are reduced.
Beijing, Beijing MunicipalityAges 18–90
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Common questions
- Are there clinical trials for gut microbiota?
- Yes. Clin2 currently lists 145 recruiting gut microbiota studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gut microbiota trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gut microbiota trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.