Clinical trials
Gut Microbiota clinical trials
Below are recruiting gut microbiota clinical trials, each written for real people, not researchers. We’re tracking 158 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07306988RecruitingPhase 4
Treating H. pylori to improve metabolic syndrome
This trial tests whether treating H. pylori infection can help improve metabolic syndrome (a group of conditions like high blood sugar, abnormal cholesterol, and high blood pressure). It aims to understand how treatment changes your gut bacteria and overall health.
Nanjing, JiangsuAges 18–65 - NCT07329595Recruiting
Tracking gut bacteria changes after severe burns
This study looks at how severe burns change the bacteria in your gut and your immune system. It will track these changes to better understand recovery and find new ways to help healing.
Debrecen, Hajdú-BiharAges 18–65 - NCT07334210Recruiting
Gut bacteria in sarcopenia and probiotic development
This study looks at gut bacteria differences between older adults with muscle loss (sarcopenia), healthy older adults, and younger adults. Results may help develop probiotics to support muscle health.
Seongnam-si, Gyeonggi-doAges 20–90 - NCT07342621Recruiting
Testing a special formula for babies with cow's milk allergy
This study tests whether a special formula with added prebiotics, probiotics, and a human milk nutrient helps manage symptoms in infants with cow's milk protein allergy. If your baby is starting a hypoallergenic formula for the first time, this trial may be an option.
Valencia, ValenciaAges Up to 10 months - NCT07363551Recruiting
Omega-3 for depression in young people
This trial tests if omega-3 fatty acid supplements can improve depression in young people by reducing inflammation and changing gut bacteria. You may be eligible if you are a young person with a current major depressive episode.
Taichung, TaichungAges 13–18 - NCT07369830Recruiting
Probiotics for bowel function after rectal cancer surgery
This trial tests whether taking a probiotic supplement (Clostridium butyricum) can improve gut health and bowel function after surgery for very low rectal cancer. It may help patients who have a temporary ileostomy and are planning to have it reversed within 6 months.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07440147Recruiting
Akkermansia and Berberine for night shift workers' insulin sensitivity
This trial tests whether taking a probiotic called Akkermansia muciniphila and a natural plant compound called berberine can improve how your body uses insulin. If you work night shifts regularly, this study may help you find a way to support your metabolic health.
Graz, StyriaAges 21 years+ - NCT07450872Recruiting
Gut health and symptoms in childhood cancer survivors
This study looks at how cancer survivors' symptoms (like pain, fatigue, or mood) are connected to the bacteria living in their gut. It aims to understand why some children have different symptom patterns after treatment, which could help doctors provide better care.
Hangzhou, ZhejiangAges 8–18 - NCT07477522RecruitingPhase 1
High-fiber diet study for solid tumor patients
This trial tests whether eating a high-fiber diet can improve your gut health, metabolism, and immune system. It is for people with solid tumors who are able to eat or use a feeding tube.
Chengdu, SichuanAges 18–75 - NCT07497711RecruitingPhase 2/Phase 3
Virtual treatment for menstrual cramps
This study tests a virtual (app-based) approach to help manage menstrual cramps. It is for people with regular periods who have moderate to severe cramp pain and want to try a non-medication option.
SingaporeAges 16–35 - NCT07499414Recruiting
Bile acid supplement for gut health in adults
This study tests whether a bile acid supplement called 7-keto lithocholic acid can positively affect your gut bacteria and reduce disease risks. Healthy adults aged 18-65 are needed.
ReadingAges 18–65 - NCT07553936Recruiting
Alternative Proteins in Mediterranean Food Supply Chains
This study tests new plant-based and alternative protein foods (like those from legumes, insects, and algae) to see if they're safe, healthy, and practical for everyday use. You'll help researchers understand how these sustainable protein options can work in Mediterranean diets.
Bologna, BOAges 18–65 - NCT07585669Recruiting
Omega-3 Supplements for New Celiac Disease Patients
This study tests whether omega-3 fatty acids (a type of fish oil supplement) can reduce inflammation and improve gut health in people newly diagnosed with celiac disease. Participants will follow a gluten-free diet while taking the supplement to see if it helps their body heal.
Santiago, Metropolitan RegionAges 18–65 - NCT07618000Recruiting
Gut Health Formula Study for Adults with Extra Weight
This study tests a special formula designed to improve your gut bacteria and body composition. Researchers will track how it affects your digestive health and weight distribution over time.
Taipei, TaiwanAges 18–65 - NCT06895018Enrolling by invitation
Grape Drink Trial for Diabetes and Fatty Liver
This study tests a drink made from grape pomace (a natural byproduct) that is rich in polyphenols—compounds that may help the liver and heart. Participants have type 2 diabetes and mild fatty liver, and researchers want to see if the drink improves liver health, blood sugar, and gut bacteria over several months.
NaplesAges 35–70 - NCT06136793Enrolling by invitation
Healthy home habits for Chinese-heritage adults
This study tests a program to help Chinese-heritage adults with heart or diabetes conditions adopt healthier eating and lifestyle habits at home. It includes online resources and support to make lasting changes.
New Brunswick, New JerseyAges 30–70 - NCT06133530Enrolling by invitation
Human milk sugars for gut health in Antarctica
This study tests whether natural sugars found in human milk (called HMOs) can improve gut health and the immune system. Researchers are looking for healthy adults who are willing to travel to Antarctica for the study.
ErfurtAges 18–65 - NCT04809688Enrolling by invitation
Study how berries affect metabolism and gut bacteria
This study looks at whether eating Saskatoon berries changes how your body uses energy (metabolism) and how your gut bacteria behave. It’s done in healthy people and may help researchers understand how foods could support overall health.
Winnipeg, ManitobaAges 18–75 - NCT07313007Recruiting
Gut bacteria chemicals in fatty liver disease
This study looks at whether the natural chemicals made by your gut bacteria from the food you eat could affect liver fat and health. If you have MASLD (a fatty liver condition), researchers want to measure these gut-produced substances to better understand the disease.
Pierre-BéniteAges 18–80 - NCT07686835RecruitingPhase 2
High-fiber diet to help immunotherapy work better in advanced melanoma
This trial tests if adding extra dietary fiber before and during immunotherapy can change gut bacteria to make the treatment more effective. It is for people with advanced melanoma who are about to start their first immunotherapy.
Nijmegen, GelderlandAges 18 years+ - NCT05646901Recruiting
Study how gut bacteria may affect loss of eating control
This study looks at how gut bacteria and the brain may be involved when people struggle to control eating. It may help researchers understand the body’s signals behind eating control problems.
Girona, GironaAges 30–65 - NCT06139224Recruiting
Gut Bacteria and Inflammation in HIV and Heavy Drinking
This study looks at how gut bacteria and inflammation interact in people with both HIV and heavy alcohol use. It aims to find new ways to improve health by understanding these connections.
Chicago, IllinoisAges 45–75 - NCT06546020Recruiting
Haskap berries for gut and metabolic health
This study tests whether a berry called Haskap can improve your gut health and how that might affect your overall health. Researchers are looking for people with and without certain metabolic risk factors to see who benefits most from adding these berries to their diet.
Bozeman, MontanaAges 35–65 - NCT06560840Recruiting
Diet study for healthy aging in people with HIV
This study tests whether a special diet aimed at improving gut health can help reduce the risk of heart disease in older adults living with HIV. If you are 40 or older, have certain heart risk factors, and are interested in making dietary changes, this study might be a good fit for you.
ShenzhenAges 40 years+
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Common questions
- Are there clinical trials for gut microbiota?
- Yes. Clin2 currently lists 158 recruiting gut microbiota studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gut microbiota trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gut microbiota trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.