Clinical trials
Head and Neck clinical trials
Below are recruiting head and neck clinical trials, each written for real people, not researchers. We’re tracking 682 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07212036Recruiting
Ultrasound for elbow fractures in children
This study uses ultrasound, a sound-wave imaging tool, to diagnose elbow fractures in children. It aims to see if ultrasound works as well as X-rays, so your child might avoid radiation.
Orlando, FloridaAges Up to 18 years - NCT07104279Recruiting
Zimmer Biomet hip implant follow-up study
This study is for people who need a hip replacement for the first time. It is testing a specific hip implant system called the Z1 Hip System and will follow patients to see how well it works over time.
Charlotte, North CarolinaAges 18 years+ - NCT05617365RecruitingPhase 1/Phase 2
Study treatment for chronic neck-related head and neck pain
This early-stage study tests a new treatment for people (women) who have long-lasting headaches and pain coming from the neck. It may help reduce symptoms, but you must match specific safety and diagnosis requirements.
East Lansing, MichiganAges 18–65 - NCT07059221RecruitingPhase 1/Phase 2
New drug combo for advanced head and neck cancer
This trial tests a new combination of drugs (SHR-A2102 and Adebrelimab) with or without other anti-cancer therapies for head and neck cancer that has come back or spread. It aims to see if these treatments can shrink tumors or slow the disease.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06996015Recruiting
SNAGs and CBT for neck pain relief
This study tests whether combining two hands-on techniques (SNAGs and CBT) can reduce neck pain, improve head posture, and help you move better. It's for people with moderate neck pain that hasn't been treated recently.
Faisalabad, Punjab ProvinceAges 18–28 - NCT06016920RecruitingPhase 1/Phase 2
Study of VB10 with pembrolizumab for advanced head and neck cancer
This trial is testing a combination of two investigational drugs (VB10 and pembrolizumab) in patients with a specific type of head and neck cancer that has returned or spread. The goal is to see if this treatment is safe and effective.
MontpellierAges 18 years+ - NCT07139990RecruitingPhase 1
Personalized radiotherapy for lung, brain, sarcoma, or head and neck cancers
This trial tests whether giving personalized radiotherapy alongside standard treatments can better control several types of cancer: small cell lung cancer, brain metastases, soft tissue sarcoma, and head and neck cancer. It aims to see if this approach helps patients live longer without their cancer growing or coming back.
Dallas, TexasAges 18 years+ - NCT06912763RecruitingPhase 2
Reversing radiation side effects in head and neck cancer
This trial tests a combined treatment (a statin and a drug that helps blood flow) to reverse long-term swelling and tissue hardening caused by head and neck radiation. It may help people who have had these side effects for more than 6 months.
Houston, TexasAges Any age - NCT04166006RecruitingPhase 2
Vaccine made from your tumor cells after surgery for rare cancers
This trial tests a personalized vaccine made from your own tumor material, aiming to lower the chance cancer returns after surgery. It is for people whose rare cancers have been removed completely and who have no standard treatment available after surgery.
Meldola, FCAges 18 years+ - NCT05878964Recruiting
Study of skin health and quality of life during cancer treatment
This trial looks at how cancer treatments (anti–PD-1/PD-L1/CTLA-4 medicines or CDK inhibitors) affect your skin and overall quality of life. You may fill out questionnaires during the study to help researchers understand changes over time.
RomaAges 18 years+ - NCT05933889Recruiting
Study of robotic throat surgery for early oropharyngeal cancer
This study looks at how well different robotic surgery approaches work for people with early oropharyngeal squamous cell carcinoma (throat cancer). You may be asked for consent for extra tissue and imaging analysis to help researchers understand patterns related to outcomes.
LondonAges 18 years+ - NCT07341737RecruitingPhase 1/Phase 2
SL-28 for advanced solid tumors that haven’t responded to treatment
This trial tests a new drug, SL-28, for people with advanced solid tumors that haven’t responded to or cannot be treated with standard therapies. It aims to find a safe dose and see if the drug can help shrink or slow the growth of your cancer.
Adelaide, South AustraliaAges 18 years+ - NCT06998342RecruitingPhase 2
Mohs surgery plus short radiation for head and neck skin cancer
This trial studies a combination of Mohs surgery and a short course of radiation therapy for people with squamous cell skin cancer of the head and neck. The goal is to see if this approach is effective with fewer side effects.
Burlington, VermontAges 18 years+ - NCT07189871RecruitingPhase 1/Phase 2
177Lu-BetaBart for advanced solid tumors
This trial tests a new radioactive drug, 177Lu-BetaBart, for people with certain advanced solid tumors that have stopped responding to other treatments. The goal is to see if it can shrink tumors or slow their growth.
Dothan, AlabamaAges 18 years+ - NCT07192068RecruitingPhase 2
Zanidatamab for HER2-altered solid tumors
This trial tests a drug called zanidatamab in people with certain cancers (endometrial, colorectal, head & neck, non-small cell lung, or sarcoma) that have a specific change in the HER2 gene. It's for those whose cancer has spread or can't be removed and who have tried at least one prior treatment.
AngersAges 18 years+ - NCT07217938RecruitingPhase 2
Testing statins for swallowing problems after radiation
This study tests whether a common cholesterol-lowering drug (pravastatin, a type of statin) can reduce swallowing problems caused by past radiation for head and neck cancer. If you have had radiation at least 2 years ago and still have trouble swallowing, this trial may help find a new way to ease those symptoms.
Melbourne, VictoriaAges 18 years+ - NCT07292168RecruitingPhase 1/Phase 2
Study of a new antibody for advanced tumors with FGFR1 protein
This trial tests an experimental antibody, OM-RCA-01, in people with advanced solid tumors that have high levels of a protein called FGFR1. It aims to see if the drug is safe and effective for those who have already tried other treatments.
Kazan'Ages 18 years+ - NCT07310758RecruitingPhase 2/Phase 3
Using ultrasound contrast to detect sentinel nodes in cancer
This trial tests whether contrast-enhanced ultrasound can help find sentinel lymph nodes (the first nodes cancer may spread to) in people with melanoma, breast, or head and neck cancer. It may reduce the need for a radioactive tracer injection.
Amsterdam, North HollandAges 18 years+ - NCT07353723RecruitingPhase 2
Combination therapy for advanced tonsil cancer
This trial tests a combination of two targeted drugs (nimotuzumab and toripalimab) with chemotherapy for people with advanced tonsil cancer that can be surgically removed. The goal is to see if this approach works better than standard treatment.
Shanxi, ProvinceAges 18–80 - NCT01788410Recruiting
MRI-guided freezing treatment for neck, head, and spine pain
This trial studies an MRI-guided procedure that “freezes” targeted nerves or joints to reduce pain in the head, neck, or spine. It may help if your pain comes from a joint problem or a compressed/damaged nerve and you can safely have MRI scans before and after the treatment.
Boston, MassachusettsAges 18 years+ - NCT07508319Recruiting
Immune system’s role in preventing laryngeal cancer
This trial studies how the immune system helps prevent laryngeal cancer. It focuses on people with a precancerous condition called laryngeal dysplasia to see if the immune response can stop cancer from developing.
Milan, MIAges 18–99 - NCT07510321Recruiting
A study of FL-261 imaging for cancer diagnosis
This trial tests a new imaging agent called FL-261 to help doctors see and stage cancers more clearly. If you have a known or suspected cancer like lung, colon, or head and neck cancer, this study may improve how your cancer is evaluated.
Wuhan, HubeiAges 18 years+ - NCT04688528Recruiting
Radiation planning to spare the opposite neck in head cancer
This trial tests a safer radiation plan that may reduce dose to the opposite (other) side of the neck while still treating the cancer spread risk. It uses special mapping to guide treatment and looks at patients whose cancer is already in an involved lymph node on one side.
Genk, LimburgAges 18 years+ - NCT01365169Recruiting
How activity level and daily function relate to cancer survival
This study looks at how physical activity (movement during the day) and a clinician-rated “day-to-day function” score relate to overall survival in people with certain cancers. It may help doctors understand who benefits most from activity-focused care and better monitoring.
Houston, TexasAges 18 years+
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Common questions
- Are there clinical trials for head and neck?
- Yes. Clin2 currently lists 682 recruiting head and neck studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a head and neck trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a head and neck trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.