Clinical trials
Head and Neck clinical trials
Below are recruiting head and neck clinical trials, each written for real people, not researchers. We’re tracking 691 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04119024RecruitingPhase 1
Gene-edited immune cells for advanced melanoma or solid tumors
This Phase 1 study tests a gene-modified immune cell treatment for advanced cancers that don’t have standard curative options. It may help by attacking cancer cells that show a specific marker called IL13Rα2 after patients receive “conditioning” chemotherapy to prepare the immune system.
Duarte, CaliforniaAges 18–75 - NCT04003051RecruitingPhase 2
Online program to help throat cancer patients swallow and cope
This trial tests a web-based program meant to help people with throat (head and neck) cancer follow swallowing exercises and use coping strategies during curative radiation treatment. It may help improve comfort and how well you can keep up with exercises while you’re getting treatment.
Fort Worth, TexasAges 18 years+ - NCT03875716Recruiting
De-intensified radiation after surgery for HPV throat cancer
This trial studies a lower-intensity (less aggressive) course of radiation therapy after curative surgery for HPV-related tonsil or base-of-tongue cancer. The goal is to see if patients can still be treated successfully while reducing side effects from radiation.
Boston, MassachusettsAges 18 years+ - NCT03740256RecruitingPhase 1
HER2-targeted oncolytic virus plus custom immune cells for solid cancers
This Phase 1 study tests a treatment plan that combines a virus designed to attack cancer with your own custom immune cells that target HER2. It aims to shrink advanced HER2-positive solid tumors (and make future options safer/more effective).
Houston, TexasAges 18 years+ - NCT03526835RecruitingPhase 1/Phase 2
Study of MCLA-158 for advanced solid tumors
This trial tests a new experimental drug called MCLA-158 (petosemtamab) for people with advanced solid tumors, especially head and neck cancer or colorectal cancer, that have not responded to standard treatments. The study aims to see if this drug can shrink tumors or slow their growth.
La Jolla, CaliforniaAges 18 years+ - NCT03702309Recruiting
Banking and testing blood samples to study cancer
This study collects blood samples to “test and store” (bank) information that may help doctors understand cancer in the future. You might be able to join if you’re an adult with confirmed cancer or a higher-than-usual risk for cancer.
Toronto, OntarioAges 18 years+ - NCT02906943Recruiting
Testing cancer tissue to guide targeted treatment choices
This trial studies advanced solid tumors by using stored tumor samples to look for molecular clues. The goal is to help doctors better choose cancer treatments that may work for your specific tumor.
Hamilton, OntarioAges 18 years+ - NCT03017573Recruiting
Cancer biobank study linking tumor, immune system, and environment
This study collects tumor and related samples from people with certain newly diagnosed cancers. Researchers use these samples to better understand how cancer cells, the surrounding tissue, and the immune system interact, which may guide better future treatments.
BordeauxAges 18 years+ - NCT02507141Recruiting
Check oral cancer images during surgery using a special camera
This study tests whether a special in-mouth imaging tool can capture clear images of oral cancer before surgery, compared with the final lab diagnosis from tissue (pathology). If the images match the pathology, it could help doctors better assess tumors using real-time imaging.
Basking Ridge, New JerseyAges 18 years+ - NCT01473784Recruiting
Robot-assisted mouth and throat surgery for head and neck tumors
This trial studies using a robot-assisted operation through the mouth to diagnose or treat certain non-cancer (benign) and cancer (malignant) tumors in the head and neck. It may help some people avoid more invasive surgery by using an approach that reaches the throat and voice box area through the mouth.
Columbus, OhioAges 18 years+ - NCT01612949Recruiting
Photos to help predict difficult breathing tube placement
This trial looks at pictures of the face and neck to help classify which people are harder to place a breathing tube. It may help anesthesiology teams prepare and choose safer steps if a tube is difficult to insert.
Winston-Salem, North CarolinaAges 18–99 - NCT00991094Recruiting
Study follow-up after proton radiation treatment
This study collects information about both short-term and long-term side effects in people who receive proton radiation. It may help doctors better understand what happens to normal tissues over time and improve follow-up care.
Houston, TexasAges 18 years+ - NCT07879313Recruiting
Smartphone use and neck pain study for university students
This study looks at how heavy smartphone use might be linked to ongoing neck pain in university students. If you have neck pain that has lasted at least three months, you may be able to help researchers understand this connection.
CairoAges 18–25 - NCT07828080Recruiting
Hip replacement using a newer stem design
This study looks at how well a newer type of hip replacement stem (called the Actis stem) works for people having their first hip replacement. It aims to see if this stem provides good outcomes for various hip conditions.
Seongnam-si, Gyeonggi-doAges 18 years+ - NCT06565910RecruitingPhase 4
Pain relief after hip surgery: long-acting vs standard numbing medicine
This study tests if a long-acting numbing medicine (bupivacaine liposome) combined with a standard numbing medicine works better for pain control after hip fracture surgery. It compares two different combinations to see which provides more effective pain relief.
Wuhan, HubeiAges 18–60 - NCT07866040Recruiting
Biofeedback exercises versus Mulligan method for neck pain
This trial compares two non-surgical treatments for ongoing neck pain: biofeedback exercises, which use sensors to help you learn to relax and strengthen neck muscles, and the Mulligan method, a hands-on technique that improves movement and posture. It aims to see which is better for reducing pain, improving mobility, and correcting posture in women.
Badr, Cairo GovernorateAges 18–45 - NCT07289789Recruiting
Breathing and Neck Exercises for Asthma with Forward Head Posture
This study tests whether Buteyko or Pilates breathing, combined with neck exercises, can improve lung function and chest expansion in people with asthma and forward head posture. It may help you breathe better if your asthma is under control and you have that posture issue.
IslamabadAges 18–40 - NCT05227924Recruiting
Testing safety and performance of a hip implant device type
This study checks how safe and well a specific brand of hip implant (SYMBOL range) works in people getting a total hip replacement. It may help by confirming the device performs as expected for primary or revision surgeries.
BeaumontAges 18 years+ - NCT07627542Recruiting
Smartphone use and neck posture in arthritis patients
This study looks at how much time people with rheumatoid arthritis or ankylosing spondylitis spend on smartphones and how it affects their neck posture, balance, and disability. Understanding this connection may help doctors give better advice about phone use and neck health.
Konya, MeramAges 18–65
Hear when a new Head and Neck trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for head and neck?
- Yes. Clin2 currently lists 691 recruiting head and neck studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a head and neck trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a head and neck trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.