Clinical trials · California
Health clinical trials in California
We’re tracking 341 recruiting health studies with a site in California — including Early Phase 1, Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07227259Recruiting
How pecans affect health
This trial studies how eating pecans every day affects health, including blood sugar and gut health. You may qualify if you are generally healthy and willing to eat pecans and provide blood and stool samples.
Davis, CaliforniaAges 45–75 - NCT07059884Recruiting
Exercise program to help people with cancer stay active
This trial tests a distance-based exercise program designed to help people on chemotherapy maintain their physical function and prevent disability. It is for patients with certain cancers who are working full-time and can participate in moderate physical activity.
Dublin, CaliforniaAges 18 years+ - NCT07259746Recruiting
Student well-being study
This trial tests a program to help students feel better and thrive in school. It may be a good fit if you are a college student looking for ways to improve your well-being.
Orange, CaliforniaAges 18 years+ - NCT07285707Recruiting
Acupuncture and herbs for long COVID
This small study tests whether acupuncture and Chinese herbal medicine can help relieve common long COVID symptoms like fatigue, cough, brain fog, and pain. It might be a good fit if you are struggling with ongoing symptoms after COVID and are looking for a treatment approach that isn't just more medication.
Whittier, CaliforniaAges 18 years+ - NCT05751473Recruiting
Reducing PTSD symptoms for first responders and frontline health workers
This study tests a way to help reduce PTSD symptoms in first responders and frontline healthcare workers. You may join a main treatment study, and some participants may also take part in follow-up questions to learn what helped.
San Diego, CaliforniaAges 18 years+ - NCT07364799Recruiting
Sound therapy for stress in detained teens
This trial tests a multi-sensory therapy called SoundHeal for teens in juvenile detention. It uses sound and vibration to help with stress, anxiety, depression, or substance use.
San Luis Obispo, CaliforniaAges 12–18 - NCT00061828Recruiting
Tracking Liver Disease in Newborns and Young Infants
This study follows babies under 6 months old who have early signs of liver disease (cholestasis) to better understand what causes it and how it progresses. Researchers will collect medical information over time to improve diagnosis and treatment.
San Francisco, CaliforniaAges Up to 6 months - NCT01327690RecruitingEarly Phase 1
Group therapy for mental health in veterans and families
This early-stage study looks at mental health outcomes for active-duty service members, veterans, and their family members after participating in group therapy sessions. If you can follow instructions and complete consent forms, this trial may help researchers understand how group therapy affects well-being in these communities.
Santa Rosa, CaliforniaAges 18–80 - NCT02016248Recruiting
Radiation “boost” for higher-risk prostate cancer
This trial studies whether adding a stronger “boost” dose of targeted radiation (SBRT) can better control higher-risk prostate cancer. It may help by increasing radiation coverage to the prostate while trying to limit treatment to surrounding areas.
Long Beach, CaliforniaAges 18 years+ - NCT00345553Recruiting
Study for children with biliary atresia
This study enrolls children and young adults with biliary atresia (a condition where bile can’t flow properly from the liver) to learn from their care and outcomes over scheduled visits. It may help researchers understand the disease better and improve future treatment.
Los Angeles, CaliforniaAges 6 months–20 years - NCT02620852Recruiting
Wisdom Study: Women’s breast cancer screening decisions
This study looks at how to decide the best breast cancer screening (like mammograms) based on your personal risk. It may help by testing a smarter way to match screening to your risk level.
Los Angeles, CaliforniaAges 30–74 - NCT02920788Recruiting
Rehab program study for mild traumatic brain injury symptoms
This trial studies whether a specific rehabilitation program (“GOALS”) helps veterans with mild traumatic brain injury (TBI) who still have thinking or memory problems. It compares the program to usual care, using regular assessments and training over time.
San Francisco, CaliforniaAges 18 years+ - NCT03380221Recruiting
Watermelon eating study for fullness and heart health markers
This study tests whether eating fresh watermelon changes how full you feel and affects markers related to heart and metabolic health. It’s aimed at adults who fit certain age and body-size ranges and can follow the study’s food rules.
San Diego, CaliforniaAges 18–55 - NCT07675590RecruitingPhase 1
Safety study of TIX100 in healthy volunteers
This study tests a new oral medication called TIX100 in healthy people to see if it is safe and how the body handles it. It is the first step in human testing, so it focuses on safety and side effects.
Chula Vista, CaliforniaAges 18–70 - NCT07675109Recruiting
Extended therapy for restless legs syndrome
This study tests a device that delivers nerve stimulation to help with restless legs syndrome (RLS). It aims to see if using the device for a longer period each night can reduce RLS symptoms and improve sleep.
Pleasanton, CaliforniaAges 21 years+ - NCT02402426Enrolling by invitation
Online brain health registry for adults
This study is building an online registry where adults can share information to help researchers find people for future brain research. Joining may help future studies get the people they need.
San Francisco, CaliforniaAges 18 years+ - NCT07410585Recruiting
Matching body clock to daily life for student well-being
This study tests if an app that helps match your daily schedule to your body's natural sleep-wake clock can improve well-being and happiness in college students. If you are a UCSD undergraduate with an Apple device, you may be able to join.
La Jolla, CaliforniaAges 18 years+ - NCT07420400Recruiting
Detecting heart shunts without needles
This trial uses a specialized ultrasound test (TEE with bubble study) to find a small opening in the heart called a PFO. It may help people who need this test to check for causes of certain health problems.
La Jolla, CaliforniaAges 18 years+ - NCT07435831Recruiting
Kimchi and gut health study
This trial tests whether eating kimchi every day for 3 weeks can improve gut health in people who are overweight. You'll be asked to eat study food daily and follow the study plan.
Davis, CaliforniaAges 19–70 - NCT07461948RecruitingPhase 3
Advanced imaging study for glioblastoma patients
This trial uses special MRI scans and a contrast agent to look at the immune environment of glioblastoma tumors. It may help doctors learn more about how the tumor responds to treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT07475702Recruiting
Brothers of the Moon and Sun: A prevention program for Latino men
This study tests a community program called Hermanos de Luna y Sol (Brothers of the Moon and Sun) designed to lower HIV risk and support Latino men who have sex with men. If you join, you'll take part in group sessions and activities in Spanish to build health and connection.
San Francisco, CaliforniaAges 18 years+ - NCT05952804RecruitingPhase 2
IVIG to help prevent infections after CAR-T treatment
This Phase 2 study tests whether IVIG (a blood product that helps fight infections) can lower infection risk after you receive CD19 CAR-T therapy. It’s meant to help protect you during the vulnerable period after CAR-T treatment.
Duarte, CaliforniaAges 18 years+ - NCT07505797Recruiting
Ultrasound imaging study for suspicious breast lesions
This study is testing a new ultrasound device (ATUSA) to see how well it can image breast lesions that have been classified as suspicious (BI-RADS 4 or 5). If you have a recent finding that needs further evaluation, this research might help improve detection methods.
Sacramento, CaliforniaAges 18–94 - NCT07528014Recruiting
Tracking Depression Treatment Outcomes Over Time
This study follows adults receiving depression treatment (esketamine, TMS, or SAINT) to understand how these therapies work and their effects over time. Researchers will assess mood, functioning, and other factors to help improve future treatment.
La Jolla, CaliforniaAges 18 years+
Where these studies are running in California
Institutions with a site for the recruiting health studies listed above.
- University of California, San Francisco · 3 studies
- Children's Hospital Los Angeles · 2 studies
- Ragle Human Nutrition Research Center · 2 studies
- University of California, Davis Medical Center · 2 studies
- BrainHealthRegistry.org
- Chapman University
- City of Hope Comprehensive Cancer Center
- Foothill College
What taking part in a health study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Common questions
- Are there health clinical trials in California?
- Yes. We're currently tracking 341 recruiting health studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a health study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a health trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New health studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.