Clinical trials · California
Health clinical trials in California
We’re tracking 342 recruiting health studies with a site in California — including Early Phase 1, Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT04604418Recruiting
Tracking outcomes during non-heart procedures in children with heart defects
This study looks at how children with congenital heart disease do during routine non-heart procedures, including medical or minor treatments that are not heart-related. It also measures how much health care they use afterward, which may help improve care planning for families.
Los Angeles, CaliforniaAges Up to 21 years - NCT04540107RecruitingPhase 1
MRI scan study to characterize lower-grade brain tumors
This Phase 1 study uses special MRI scans (including a form of MR spectroscopy) to better understand lower-grade gliomas. It is designed to test how well the imaging can “characterize” the tumor and to improve understanding for treatment planning.
San Francisco, CaliforniaAges 18 years+ - NCT04543461Recruiting
Lung health study for young adults in the U.S.
This study follows young adults to learn about lung health and risk factors. It may help researchers better understand how breathing symptoms and exposures affect future lung outcomes.
Los Angeles, CaliforniaAges 25–35 - NCT04410302Recruiting
Personalized tumor research for bladder, lung, stomach, and liver cancers
This study uses a small sample of your tumor to grow it in the lab, which may help researchers understand your cancer better and find treatments that work for you.
Orange, CaliforniaAges 21–100 - NCT04378790RecruitingPhase 3
Patch one eye by itself or together with glasses
This study tests whether children with amblyopia (lazy eye) should start patching one eye after glasses first, or start patching at the same time as glasses. The goal is to find the best approach to improve vision.
Berkeley, CaliforniaAges 3–13 - NCT04485559RecruitingPhase 1
Trametinib and everolimus for recurrent gliomas
This trial tests two drugs, trametinib and everolimus, for children and young adults with recurrent or progressive gliomas (a type of brain tumor). The goal is to see if this drug combination is safe and effective in treating these tumors.
San Diego, CaliforniaAges 1–25 - NCT04390009RecruitingEarly Phase 1
Whole-body PET scans in people with multiple sclerosis
This early study tests how whole-body PET-CT scans can be used in people with multiple sclerosis (and compares with healthy volunteers). It may help researchers understand what the scan can show in MS throughout the body.
Ladera Ranch, CaliforniaAges 25–55 - NCT04297020Recruiting
Checking brain health in breast cancer survivors
This study looks at differences in brain function in people who have had breast cancer, compared with certain people without that history. It’s testing how brain health changes after breast cancer and relates to mood, thinking, and daily functioning.
Los Angeles, CaliforniaAges 35–65 - NCT04356274Enrolling by invitation
Improving access to addiction and mental health care at VA clinics
This study tests an approach to help VA clinics reach more Veterans with proven treatments for addiction and mental health conditions. It focuses on clinic-level processes (not individual medications) to increase how widely evidence-based care is delivered.
Palo Alto, CaliforniaAges 18 years+ - NCT04248127Recruiting
Honey yogurt to improve gut health and mild inflammation
This study tests whether honey-flavored yogurt can improve gut health and “low-grade” inflammation in middle-aged and older women after menopause. You may be asked to follow a yogurt-focused plan and avoid certain foods or supplements to see the effect.
Davis, CaliforniaAges 45–65 - NCT04181138Recruiting
Study of childhood primary sclerosing cholangitis types
This study follows children and young adults with primary sclerosing cholangitis (PSC) to understand the condition and how it shows up on scans or biopsy. It may help doctors better recognize PSC and choose the best next steps for care.
Los Angeles, CaliforniaAges 2–25 - NCT03957928Recruiting
Mango pulp study for hunger and heart-health markers
This study tests whether eating fresh mango pulp can make you feel fuller (less hungry) and improve “heart-health” measurements. It may help people who are interested in diet changes, especially those with higher body weight and related health risks.
San Diego, CaliforniaAges 18–55 - NCT04096586Recruiting
Study tests how watermelon affects fullness and digestion
This study looks at whether eating watermelon changes how full you feel and how your digestion works. It’s for generally healthy people and skips those with certain health factors or who can’t eat watermelon safely.
San Diego, CaliforniaAges 10–55 - NCT03380221Recruiting
Watermelon eating study for fullness and heart health markers
This study tests whether eating fresh watermelon changes how full you feel and affects markers related to heart and metabolic health. It’s aimed at adults who fit certain age and body-size ranges and can follow the study’s food rules.
San Diego, CaliforniaAges 18–55 - NCT04005976Recruiting
Genetic study for inherited aortic disease
This trial is for people with inherited (family-run) aortic enlargement or aneurysm caused by a specific DNA gene change. It uses genetic information to guide more precise care, which may help tailor monitoring and treatment for you and your family.
Newport Beach, CaliforniaAges Any age - NCT03869814Recruiting
Blood test to study cancer signals without invasive procedures
This study looks at a non-invasive blood test to detect cancer-related “signal patterns” and see how well they match different types of cancer. It may help researchers learn better ways to find or understand cancer using less invasive testing.
San Diego, CaliforniaAges 21–80 - NCT03774758Recruiting
Blood tests to estimate lung cancer risk over 3 years
This study looks for blood “biomarkers” (measurable signs in blood) that may help predict who is at higher or lower risk related to lung cancer. You would have blood samples taken and then be followed with visits for up to 3 years.
San Francisco, CaliforniaAges 40 years+ - NCT03552705RecruitingPhase 2
Tranexamic acid to reduce knee inflammation after ACL injury
This Phase 2 study tests whether tranexamic acid can reduce swelling and protect knee cartilage after an ACL injury. It may help by limiting bleeding-related inflammation in the injured joint soon after injury.
Stanford, CaliforniaAges 18–30 - NCT03463954Recruiting
Laser treatment trial for small breast tumors
This trial tests a focused laser treatment (Novilase®) to destroy small, cancerous breast tumors while aiming to work with standard care. It may help people who have an early, localized tumor that can be clearly seen on imaging so doctors can guide the laser safely.
Rancho Mirage, CaliforniaAges 18 years+ - NCT03388606Recruiting
Studying adolescent depression and how to treat it
This study looks closely at how depression shows up in teens and tests approaches to treatment. It may help teens and families better understand depression and get access to structured care as part of research.
Los Angeles, CaliforniaAges 11–25 - NCT03380078Enrolling by invitation
Training programs to better support kids with autism
This study tests an organized training plan meant to help mental health programs and schools support children with autism. It involves leaders, therapists/providers, and parents who complete brief surveys and assessments to see what improves care and services.
Westwood, Los Angeles, CaliforniaAges 18 years+ - NCT03258658RecruitingPhase 1
Testing a personalized urethra repair made from your own tissue
This early study tests whether an engineered urethral patch made from your own body tissue is safe and workable for urethral strictures (narrowing that blocks urine flow). It is mainly looking for safety and how feasible the procedure and follow-up are, not proven cure yet.
San Francisco, CaliforniaAges 21–75 - NCT02920788Recruiting
Rehab program study for mild traumatic brain injury symptoms
This trial studies whether a specific rehabilitation program (“GOALS”) helps veterans with mild traumatic brain injury (TBI) who still have thinking or memory problems. It compares the program to usual care, using regular assessments and training over time.
San Francisco, CaliforniaAges 18 years+ - NCT02825654Enrolling by invitation
Deployed Veterans Study of Service and Health
This study looks at how military service and deployment experiences relate to health and wellbeing in veterans who served after 9/11. It may help researchers understand which factors affect long-term health.
San Diego, CaliforniaAges Any age
Where these studies are running in California
Institutions with a site for the recruiting health studies listed above.
- University of California, San Francisco · 6 studies
- University of California, Davis · 3 studies
- University of California, Los Angeles · 3 studies
- San Diego State University · 2 studies
- San Francisco VA Medical Center · 2 studies
- Stanford University · 2 studies
- Brain Health Alliance
- Children's Hospital Los Angeles
What taking part in a health study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Common questions
- Are there health clinical trials in California?
- Yes. We're currently tracking 342 recruiting health studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a health study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a health trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New health studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.