Clinical trials · California
Health clinical trials in California
We’re tracking 341 recruiting health studies with a site in California — including Phase 2 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07552311Recruiting
Fitbit AI Care Planning Study
This study tests a new artificial intelligence tool designed to help create personalized health plans using your Fitbit data and Google account. Researchers want to learn if this AI-powered planning tool can help you better manage your health.
Mountain View, CaliforniaAges 18 years+ - NCT07561541RecruitingPhase 4
Extended Antibiotics for Diabetic Leg Fracture Surgery
This study tests whether taking antibiotics for a longer time helps prevent infections in people with poorly controlled diabetes who need surgery for a lower leg or foot fracture. Since diabetes makes infections more likely after surgery, extra antibiotics might reduce that risk.
Los Angeles, CaliforniaAges 18 years+ - NCT07580222Recruiting
Using Mobile Technology to Track Knee Arthritis Health
This study uses smartphone or tablet technology to measure how your knee osteoarthritis (wear-and-tear arthritis) changes over time. You'll be helping researchers understand how well a previous arthritis treatment works by tracking your knee health at home.
Palo Alto, CaliforniaAges 30 years+ - NCT07606625RecruitingPhase 4
Nasal spray for dry eye disease and tear film stability
This study tests whether a nasal spray can improve dry eye symptoms and tear production in people with mild to moderate meibomian gland dysfunction (a common cause of dry eye). You'll use the spray daily while the research team monitors your eye health and comfort over several weeks.
Berkeley, CaliforniaAges 18 years+ - NCT07609394Recruiting
Duchenne and Becker Muscular Dystrophy Health Records Study
This study collects electronic health records (medical information already in your doctor's computer system) from people with Duchenne or Becker muscular dystrophy, or female carriers of these conditions. Researchers will use this data to better understand the diseases and improve care over time.
Sacramento, CaliforniaAges Any age - NCT07641413Recruiting
How lungs and heart change over a lifetime of health
This study follows healthy adults over decades to understand how lung and heart function naturally change with age. Researchers will measure your breathing and heart health to help them spot early warning signs of disease in future patients.
San Francisco, CaliforniaAges 24–68 - NCT07642414Recruiting
Digital program combining exercises and mindfulness for migraines
This 12-week online program uses exercises, mindfulness, and digital tracking to help reduce migraines. You'll work with the app on your smartphone while staying on your current migraine medications.
San Francisco, CaliforniaAges 18 years+ - NCT07650656RecruitingPhase 2
Fluorescence-Guided Surgery to Improve Sarcoma Tumor Removal
This trial tests a special dye and imaging technique to help surgeons see and remove sarcoma tumors more completely. The goal is to reduce the chance that cancer cells are accidentally left behind during surgery.
Duarte, CaliforniaAges Any age - NCT07657988Recruiting
Tirbanibulin for actinic keratosis on the face
This study tests a cream called tirbanibulin (Klisyri) for adults with 4 to 12 actinic keratosis (AK) spots on their face. It aims to see how well the treatment works when applied to a larger area of the face in everyday medical practice.
Manhattan Beach, CaliforniaAges 18 years+ - NCT07631442Enrolling by invitation
Digital Health Monitoring for Primary Biliary Cholangitis
This study uses a smartphone app or digital platform to track how you're feeling day-to-day if you have primary biliary cholangitis (PBC), a liver condition where your immune system damages bile ducts. Researchers want to see if this digital monitoring helps them better understand and manage PBC symptoms.
Redwood City, CaliforniaAges 18 years+ - NCT07336615Enrolling by invitation
Study of CLB101 for gut health in overweight adults
This study tests an investigational probiotic called CLB101 to see if it can improve gut health and ease digestive symptoms in people who are overweight. You will take a daily capsule or a placebo, collect stool and blood samples, and track what you eat.
Los Angeles, CaliforniaAges 18–65 - NCT07197216Enrolling by invitation
Tap trust program for water security and drinking
This trial tests a program called Tap Trust to see if it can help families in certain childcare centers feel more secure about their water and drink more water. If you are a parent or caregiver of a preschooler from a specific study group, this might be for you.
Stanford, CaliforniaAges 18 years+ - NCT07167875Enrolling by invitation
Digital coaching trial to improve toothbrushing habits
This study tests if personalized coaching through a smartphone app helps people stick to better toothbrushing habits. Participants use an electric toothbrush and app for 19 weeks to see if coaching improves oral hygiene.
Santa Cruz, CaliforniaAges 18–80 - NCT07064070Enrolling by invitation
Teen sexual health services study
This study tests a technology-based program to help teens access sexual health services. It may help if you have a teen who is 11–17 and has a check-up coming up.
San Francisco, CaliforniaAges 11–17 - NCT07030322Enrolling by invitation
Using a personal exoskeleton at home: health and cost study
This study looks at how using a wearable robotic exoskeleton in your home and community affects your health and finances. If eligible, you would use the device with a trained support person to see if it helps with daily mobility.
San Rafael, CaliforniaAges 18 years+ - NCT06999369Enrolling by invitation
Heart failure nutrition app study
This study tests a digital nutrition tool to help people with heart failure improve their health. It is for patients recently hospitalized or seeing their doctor regularly.
Walnut Creek, CaliforniaAges 18–89 - NCT06976502Enrolling by invitation
Health eHeart Biobank
This trial collects blood and tissue samples from people with and without heart disease to study heart health. If you are 18 or older and either a UCSF patient, a family member of a heart patient, or have no heart disease, you may be able to help.
San Francisco, CaliforniaAges 18 years+ - NCT06952491Enrolling by invitation
Study on substance use and well-being
This trial tests a program to help people who use substances like cannabis, tobacco, or prescription drugs for nonmedical reasons. It aims to improve well-being and confidence in managing health.
San Mateo, CaliforniaAges 21 years+ - NCT06906653Enrolling by invitation
Proactive care for newly diagnosed type 2 diabetes
This trial tests a new, proactive approach to help people newly diagnosed with type 2 diabetes manage their condition through better initial care and support. If you’re a Kaiser Permanente Northern California member, you may get extra resources and guidance right from the start.
Pleasanton, CaliforniaAges 18–74 - NCT06835582Enrolling by invitation
Checking Methadone and Its Breakdown Levels
This study is checking the levels of methadone and its breakdown products in your blood. It helps make sure the medication is working safely for conditions like opioid use disorder or chronic pain.
Lemon Grove, CaliforniaAges 18–70 - NCT06763770Enrolling by invitation
Digital support for young adult cancer survivors
This trial tests a digital program that combines self-management tools and peer mentoring to help young adults who had childhood cancer transition to long-term follow-up care.
Los Angeles, CaliforniaAges 18–25 - NCT06454019Enrolling by invitation
Phone reminders to help start your new health plan
This study tests whether phone calls or reminders can help people who lost Medi-Cal and were automatically enrolled into a Covered California silver plan but haven't started using it. They want to see if a simple phone nudge makes it easier to get coverage.
Sacramento, CaliforniaAges Any age - NCT06430853Enrolling by invitation
Pregnancy support study for moms with anxiety or depression
This study tests if a mental health program during pregnancy can help mothers with past or current anxiety or depression. You'll get support and you may feel better and have a healthier pregnancy.
Stanford, CaliforniaAges 18 years+ - NCT06262282Enrolling by invitation
Phage therapy for stubborn NTM infection in cystic fibrosis
This trial tests whether a special virus therapy (phage) can help clear stubborn NTM lung infections in people with cystic fibrosis who have been on antibiotics for over a year without success. Participants will continue their antibiotics while receiving the phages.
Los Angeles, CaliforniaAges 6 years+
Where these studies are running in California
Institutions with a site for the recruiting health studies listed above.
- Stanford University · 3 studies
- University of California, San Francisco · 2 studies
- University of Southern California · 2 studies
- 2121 N. California Blvd., Suite 310
- Ablon Skin Institute and Research Center
- Children's Hospital Los Angeles
- City of Hope Comprehensive Cancer Center
- Covered California
What taking part in a health study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Common questions
- Are there health clinical trials in California?
- Yes. We're currently tracking 341 recruiting health studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a health study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a health trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New health studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.