Clinical trials · California
Health clinical trials in California
We’re tracking 341 recruiting health studies with a site in California — including Phase 1, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06796686RecruitingPhase 1
HIV vaccine safety and immune response study for healthy adults
This trial tests a new two-part HIV vaccine regimen in healthy adults without HIV. The goal is to see if it is safe and produces an immune response that could help prevent HIV.
San Francisco, CaliforniaAges 18–55 - NCT06797245Recruiting
App-based treatment for overactive bladder in women
This trial tests a prescription digital app to help women with overactive bladder (OAB) symptoms. It may be a good fit if you are a woman over 22 with bothersome OAB and are willing to use the app instead of other treatments for 8 weeks.
Palo Alto, CaliforniaAges 22 years+ - NCT06837181Recruiting
Understanding diabetes complications in cystic fibrosis
This study looks at how long-term diabetes affects people with cystic fibrosis. It helps researchers understand complications and improve care.
Los Angeles, CaliforniaAges 12 years+ - NCT06854198Recruiting
Glaucoma screening for at-risk Californians
This study tests whether offering eye exams at a health center helps find glaucoma early in people who are at higher risk. It may help you catch vision problems before they get worse.
Oakland, CaliforniaAges 50 years+ - NCT06870136Recruiting
Lion's Mane supplement for memory and focus
This study tests a Lion's Mane supplement to see if it helps with memory, focus, and overall thinking. If you are between 40 and 75 and have mild concerns about your thinking, you may be able to take part.
Los Angeles, CaliforniaAges 40–75 - NCT06872190Recruiting
CDS tool for opioid use disorder in the ED
This trial tests a clinical decision support tool for emergency department providers at UCSF. It helps doctors give better care that considers social needs alongside opioid use treatment. The study will ask providers and patients about how well this tool works.
San Francisco, CaliforniaAges 18 years+ - NCT06891755Recruiting
Lung deflation procedure for severe emphysema
This study tests a bronchoscopic treatment to release trapped air in severely hyperinflated lungs caused by emphysema. It may help you breathe easier if you have advanced COPD and meet specific lung function and imaging criteria.
Sacramento, CaliforniaAges 40–84 - NCT06910761RecruitingPhase 2
Radiation for cancer spread to brain lining
This trial tests whether a precise type of radiation to the brain and spine (craniospinal irradiation) can help control cancer that has spread to the lining of the brain and spinal cord (leptomeningeal disease) in people with breast cancer or non-small cell lung cancer. The goal is to improve symptoms and slow disease progression.
Irvine, CaliforniaAges 18 years+ - NCT06941519Recruiting
Addressing social needs to improve health in adults with chronic conditions
This program helps adults with multiple health conditions who also face social challenges like food or housing problems. It connects you with support to improve your health and close gaps in your care.
Pleasanton, CaliforniaAges 18 years+ - NCT06943599Recruiting
Improving Eye Care After Screening
This study looks at better ways to help people get follow-up eye care after a screening. If you were in the VIEW II study and were referred to an eye hospital, this trial may offer strategies to support you in getting that care.
San Francisco, CaliforniaAges 60 years+ - NCT06999356Recruiting
Salud Diabetes: Lifestyle Changes and Glucose Monitoring Study
This study tests if combining lifestyle coaching with a continuous glucose monitor (CGM) helps people with type 2 diabetes improve their blood sugar control. You'll track your glucose levels using a study device and see how daily habits affect them.
Santa Barbara, CaliforniaAges 18–89 - NCT07011914Recruiting
MS care study for young adults
This study looks at how to improve care for young adults with relapsing-remitting MS. It focuses on people who are Black, Hispanic, or have limited income.
San Francisco, CaliforniaAges 18 years+ - NCT07046260Recruiting
Blood test study for early cancer detection
This study is testing a new blood test to help doctors find cancer earlier. If you are 45 or older and have symptoms that might be cancer, or were recently diagnosed with cancer, you may be able to join.
Coronado, CaliforniaAges 45 years+ - NCT07095894RecruitingPhase 3
Glasses or eye drops for slowing nearsightedness in kids
This study tests whether special glasses or low-dose atropine eye drops can slow down worsening nearsightedness in children. It compares four groups: glasses alone, eye drops alone, both together, or a placebo (no active treatment).
Fullerton, CaliforniaAges 5–11 - NCT07107386Recruiting
Study on health changes in older adults
This study looks at how different parts of your health—like activity, sleep, and biology—change over time in healthy older adults. You'll wear some devices and use a smartphone app to help researchers learn more about aging.
Novato, CaliforniaAges 55 years+ - NCT07116876Recruiting
Placental membrane vs standard care for diabetic foot ulcers
This study tests a special wound covering made from donated placental tissue to see if it helps diabetic foot ulcers heal better than usual care. It may be an option for people with diabetes who have a foot sore that hasn't healed after 30 days.
Castro Valley, CaliforniaAges 21–80 - NCT07148245Recruiting
Study of immunotherapy side effects in melanoma
This study looks at how people with advanced melanoma (a serious skin cancer) feel during treatment with immunotherapy. It aims to better understand the symptoms they experience, so doctors can help manage them.
San Francisco, CaliforniaAges 18 years+ - NCT07176793Recruiting
Breastfeeding support after gestational diabetes
This study tests a breastfeeding support program for people who had gestational diabetes during pregnancy. The goal is to see if this support helps them breastfeed longer and stay healthy.
Sacramento, CaliforniaAges 18 years+ - NCT07189234RecruitingPhase 2
Time-restricted eating for better heart health
This trial tests if eating all your meals within a shorter window each day can improve blood sugar, blood pressure, and cholesterol. You may qualify if you have prediabetes or metabolic syndrome and eat over 12 hours daily.
La Jolla, CaliforniaAges 18–75 - NCT07218510RecruitingPhase 2
Venetoclax, obinutuzumab, then epcoritamab for untreated CLL/SLL
This trial tests a new combination of three drugs for people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have not had treatment yet. The goal is to see if this approach helps control the disease with fewer side effects.
Irvine, CaliforniaAges 18 years+ - NCT07219251Recruiting
Veterans with lung cancer needed for study
This study wants to learn more about the experiences of veterans with lung cancer. If you are receiving cancer treatment or recently finished it, you may be able to join.
Palo Alto, CaliforniaAges 18 years+ - NCT07220343Recruiting
Using phones and watches to check on teens and young adults with cancer
This study uses your smartphone and a smartwatch to track your daily activity and mood, helping researchers learn how to better support teens and young adults with cancer. It may help improve mental health care for people your age dealing with cancer.
Palo Alto, CaliforniaAges 10–25 - NCT07220681Recruiting
Integrated Care for PTSD
This study tests whether combining different treatments can help Veterans with PTSD. It focuses on those who can receive Cognitive Processing Therapy (CPT) at a VA site.
San Diego, CaliforniaAges 18 years+ - NCT07221370RecruitingPhase 2/Phase 3
Vancomycin to prevent C. diff infection in ICU patients
This trial tests whether giving vancomycin through a tube into the stomach can prevent a serious gut infection called C. diff in people who are very sick in the ICU and taking antibiotics. If you qualify, you might receive this medicine to lower your risk.
Moreno Valley, CaliforniaAges 18 years+
Where these studies are running in California
Institutions with a site for the recruiting health studies listed above.
- University of California, San Francisco · 5 studies
- Stanford University · 4 studies
- City of Hope Comprehensive Cancer Center · 2 studies
- City of Hope Orange County Lennar Foundation Cancer Center · 2 studies
- University of California, Davis Medical Center · 2 studies
- Altman Clinical and Translational Research Institute
- Bay Area Foot Care
- Baywell Health
What taking part in a health study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Common questions
- Are there health clinical trials in California?
- Yes. We're currently tracking 341 recruiting health studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a health study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a health trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New health studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.