Clinical trials
Heart Diseases clinical trials
Below are recruiting heart diseases clinical trials, each written for real people, not researchers. We’re tracking 749 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05873881RecruitingPhase 3
Colchicine and vitamin B1 for ischemic heart failure
This study tests whether colchicine and thiamine (vitamin B1) can improve outcomes in people with heart failure caused by blocked or narrowed heart arteries. It’s mainly for people with moderate-to-severe symptoms and reduced heart pumping ability.
Hamilton, OntarioAges 45 years+ - NCT05868616Recruiting
Checking heart resynchronization timing with a noninvasive test
This trial evaluates a noninvasive way to assess who should get Cardiac Resynchronization Therapy (CRT), and to check results after implantation. If you fit the heart rhythm and heart pump criteria, the approach may help confirm whether CRT is appropriate for you.
OsloAges 18–80 - NCT06670768Recruiting
Comparing two heart imaging tests for blocked arteries
This trial compares two heart imaging tests (SPECT and coronary CTA) to see if a newer method gives a clearer picture of blood flow. If you have been referred for one of these tests, you may be able to help by also having the other test done at no extra risk.
Budapest, BudapestAges 18 years+ - NCT04604418Recruiting
Tracking outcomes during non-heart procedures in children with heart defects
This study looks at how children with congenital heart disease do during routine non-heart procedures, including medical or minor treatments that are not heart-related. It also measures how much health care they use afterward, which may help improve care planning for families.
Los Angeles, CaliforniaAges Up to 21 years - NCT04217421RecruitingPhase 3
Allopurinol for newborns needing heart surgery with bypass
This trial tests whether the medicine allopurinol can protect the brain and heart in newborns with serious congenital heart disease who need heart surgery soon after birth. It may help reduce injury during and around surgery that uses a heart-lung machine (cardiopulmonary bypass).
GroningenAges Up to 1 month - NCT06712862Recruiting
Testing heart muscle health with PET/MR scan
This study uses a special imaging test (PET/MR) to check if damaged heart muscle is still alive and can recover. It is for people with severe blocked arteries and weak heart pumping function who are planning bypass surgery or stem cell treatment.
Shanghai, Shanghai MunicipalityAges Up to 80 years - NCT07449325Recruiting
Heart sinus reducer for chest pain from small vessel disease
This trial tests a device placed in a heart vein (the coronary sinus) to improve blood flow and reduce chest pain in people with coronary microvascular dysfunction (small blood vessel disease). It aims to help those who still have symptoms despite taking heart medications.
New Haven, ConnecticutAges 18 years+ - NCT06644742Recruiting
PKP2 heart condition natural history study
This study is for people with a specific genetic heart condition (PKP2-related arrhythmogenic cardiomyopathy) who already have an ICD. It does not test a new treatment but instead follows participants over time to learn more about the condition.
Boston, MassachusettsAges 12 years+ - NCT07119424Recruiting
SGLT2 inhibitor study for older adults
This study looks at how a class of diabetes and kidney drugs called SGLT2 inhibitors affect older adults. It aims to understand the benefits for your kidneys and metabolism.
Milan, MilanAges 65 years+ - NCT01280825Recruiting
Testing how to use genetic medicine results in routine care
This study looks at how to put genetic testing results (pharmacogenomics) into regular doctor care. It aims to see whether using the results helps doctors choose safer, better-matched medications.
Chicago, IllinoisAges 18 years+ - NCT06374277Recruiting
Pharmacy Coaching to Help After Hospital Stay
This study tests a program where a pharmacist helps you manage your medications after you leave the hospital. It is for people with long-term health conditions who want to stay on track with their medicines.
Knoxville, TennesseeAges 18 years+ - NCT06603363Recruiting
Statin effects on heart artery plaques seen on CT scans
This trial studies how short-term statin therapy changes plaque buildup in heart arteries. It uses CT scans to see if statins can make plaques more stable and reduce heart risks.
Budapest, BudapestAges 45–75 - NCT07478354Recruiting
Heart Tissue and Blood Study for Pediatric Heart Disease
This study collects samples (blood, tissue, and other specimens) from people of all ages who have or are at risk for pediatric heart disease. The goal is to build a research bank to better understand these conditions and develop new treatments.
Cincinnati, OhioAges Any age - NCT05610787Enrolling by invitation
Testing a device that helps move an EXCOR pediatric heart pump
This trial studies an “active driving” system that controls the EXCOR pediatric heart pump. It’s meant for children who need a heart pump as a bridge to heart transplantation, to help the pump work more safely and effectively.
Los Angeles, CaliforniaAges Up to 21 years - NCT06434207Recruiting
Heart defect study in newborns to understand blood clots
This study looks at tiny particles from cells in newborns with heart defects to understand blood clot risks. It aims to find ways to prevent clots after heart surgery.
Boston, MassachusettsAges 1 day–1 week - NCT00573027Recruiting
Study of heart pain from small artery heart disease
This trial studies people who have chest pain (angina) due to problems with the heart’s small arteries, not a big blockage. It aims to test whether treatment approaches can help these patients by better understanding the cause of their heart-related symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT07569458Recruiting
Online therapy for heart disease patients with depression or anxiety
This trial tests an online program designed to help people with heart disease who are also experiencing depression or anxiety. The program is personalized to your needs and delivered through a computer or tablet over several weeks.
AalborgAges 18 years+ - NCT06675448Recruiting
Best practices for heart failure with leaky mitral valve
This trial compares two treatment approaches for people with heart failure and a leaky mitral valve (mitral regurgitation). It aims to find which strategy leads to better outcomes. You may be eligible if your heart function is reduced and you have symptoms despite standard treatments.
Falls Church, VirginiaAges 18–99 - NCT07268170Enrolling by invitationPhase 2/Phase 3
Heart rate control before heart CT scan
This trial tests two medicines to lower heart rate before a cardiac CT scan in adults who need the scan. It is for people whose heart rate is naturally a bit fast (over 65 beats per minute) but not too fast (under 100 bpm).
HerningAges 30–80 - NCT04706481Recruiting
Use of stored, de-identified samples for research
This trial is for people who already agreed to let researchers use their stored biological samples and medical information that has been removed of personal identifiers. It may help future studies by allowing researchers to analyze existing samples without using new samples from you.
Hong KongAges Any age - NCT07351656Recruiting
AI heart checks for young adults, adults, and pregnant women
This study uses artificial intelligence (AI) to look at heart signals (electrocardiography or ECG) and ultrasound images of the heart to check for heart disease. It aims to better understand heart health in different groups of people.
Rochester, MinnesotaAges 18 years+ - NCT06006819Recruiting
Acute heart failure with chronic kidney disease study
This trial studies how certain markers in the blood can predict outcomes in people with acute heart failure who also have chronic kidney disease. If you qualify, researchers will follow your health during this hospital stay.
Taipei, Baitou DistrictAges 20–90 - NCT06003023Recruiting
Physical activity study for teens with congenital heart disease
This study looks at how teens and young adults with moderate to complex congenital heart disease can improve their physical activity. You might be eligible if you're between 15 and 25, have a heart condition, and get care at Nationwide Children's Hospital or Ohio State University.
Columbus, OhioAges 15–25 - NCT07259512RecruitingPhase 4
Ramipril once or twice a day for kidney and heart health
This trial tests whether taking ramipril once or twice daily better protects kidney function in people with both chronic kidney disease (stages 3-5, not on dialysis) and heart failure with low pumping strength. It aims to find the best dosing schedule to help both organs.
Kartasura, Central JavaAges 18 years+
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Common questions
- Are there clinical trials for heart diseases?
- Yes. Clin2 currently lists 749 recruiting heart diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.