Clinical trials
Heart Diseases clinical trials
Below are recruiting heart diseases clinical trials, each written for real people, not researchers. We’re tracking 749 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06049420Recruiting
Lifestyle medicine for rural patients with chronic disease
This trial tests whether exercise therapy can help people with two or more chronic conditions like obesity, diabetes, or heart disease. It's designed for rural patients and requires a referral from your doctor.
Lewisburg, West VirginiaAges 18–64 - NCT03011697Recruiting
Heart valve disease registry for adults
This study enrolls adults in the hospital with certain heart valve problems to track their health over time. It may help doctors better understand how valve disease behaves and what outcomes look like in real life.
Hangzhou, ZhejiangAges 18 years+ - NCT07252310Enrolling by invitationPhase 4
Smartphone app to find best beta blocker dose for heart failure
This study uses a smartphone app to test how different beta blocker doses work best for you. It's for older adults with stable heart failure who want to fine-tune their treatment.
New York, New YorkAges 65 years+ - NCT06927739RecruitingPhase 2
Orticumab for heart artery inflammation after a heart attack
This trial tests a drug called orticumab to see if it can reduce inflammation in the arteries of the heart after a heart attack. It may help prevent future heart problems.
Los Angeles, CaliforniaAges 18 years+ - NCT06409585Recruiting
Heart muscle disease imaging study for scarring
This study uses advanced imaging (PET/MR or PET/CT) to look at scarring (fibrosis) in the heart muscle. It is for people with various heart muscle diseases, including heart failure with preserved pumping, thickened heart muscle, high blood pressure-related heart damage, heart inflammation, and others.
Edinburgh, ScotlandAges 30–90 - NCT06559332Recruiting
Heart artery checks during aortic valve replacement
This study tests different ways to check for blocked heart arteries in patients getting a new aortic valve through a tube in the leg. It aims to find the best approach to guide treatment.
BernAges 70 years+ - NCT06909682Recruiting
AI monitoring with wearables for chronic heart failure
This trial tests an AI system that uses wearable devices and mini-invasive tools to monitor people with chronic heart failure. The goal is to detect changes early and help manage the condition at home.
SalernoAges 19 years+ - NCT07525843Recruiting
Well-being education program for teens with heart disease
This study tests whether a special education program about managing emotions and stress helps teenagers with moderate-to-severe congenital heart disease (a heart condition from birth) feel better and cope with their condition. Participants attend sessions and complete surveys over time.
Stanford, CaliforniaAges 12–17 - NCT07029230Recruiting
Blood test during heart surgery to predict heart failure in kids
This study looks at a substance called sST2 in the blood of children having heart surgery. The goal is to see if sST2 levels can help doctors predict heart failure after surgery.
Zurich, Canton of ZurichAges Up to 18 years - NCT06788275Recruiting
Can exercise improve blood vessel health after a heart attack?
This study looks at whether aerobic exercise can improve blood vessel health in people who have had a heart attack or chest pain (angina). If you qualify, you'll join a monitored exercise program.
Alicante, AlicanteAges 45–75 - NCT03217006Recruiting
Compare one vs multiple heart artery grafts for bypass
This study looks at whether using one artery graft or multiple artery grafts during heart bypass surgery works better for people with specific coronary artery disease. You may be randomized to one approach, and the trial team will follow outcomes after surgery.
Boulder, ColoradoAges 18–70 - NCT05367297Recruiting
Registry study of heart plaque in South Asian adults
This study tracks coronary plaque (fatty deposits in heart arteries) in South Asian adults and compares them with people of other backgrounds. You may be asked to have a special heart CT scan and basic measurements to help researchers understand differences in heart disease risk.
Dallas, TexasAges 18 years+ - NCT06307262Recruiting
European registry for tricuspid valve repair
This trial is a registry that collects information on patients who have had a minimally invasive procedure to fix a leaky tricuspid valve. By joining, you help doctors learn more about how well these devices work over time.
Munich, BavariaAges 18 years+ - NCT06570902Recruiting
Heart monitor vest after first bypass surgery
This study tests a wearable heart monitor vest (WCD) for people who have had their first coronary bypass surgery and have a weakened heart pump (ejection fraction below 35%). The vest watches for dangerous heart rhythms and can shock the heart back to normal if needed.
Bad Nauheim, HesseAges 18 years+ - NCT06634121Recruiting
Comparing MitraClip and PASCAL for mitral valve repair
This trial compares two devices (MitraClip and PASCAL) for repairing a leaky mitral valve (mitral regurgitation). The goal is to see which device works better in a wide range of patients who need this type of repair.
Munich, BavariaAges 18 years+ - NCT04073420Recruiting
Cardiac surgery registry to track Medtronic device outcomes
This registry collects real-world information from people who have had—or plan to have—an eligible Medtronic cardiac surgery device. It aims to better understand how these treatments do over time and help guide future care.
Marietta, GeorgiaAges Any age - NCT07092644Recruiting
Preeclampsia and baby heart defects: mother's heart study
This study looks at the link between preeclampsia (a pregnancy complication with high blood pressure) and a mother's heart health when her baby has a heart problem. The goal is to understand how the mother's heart adapts during pregnancy in these cases.
RomaAges 18 years+ - NCT06083168Recruiting
Heart disease in chronic kidney disease study
This study is looking at the link between kidney disease and heart disease. It aims to understand how heart problems affect people with chronic kidney disease. The trial does not test a new drug, but rather follows patients to learn more about their health.
OlsztynAges 18 years+ - NCT07095634Enrolling by invitation
Heart risk study for Crohn's and colitis patients
This study looks at heart health in people with Crohn's disease or ulcerative colitis. It aims to understand the risk of heart problems over 2 years.
San Donato Milanese, MilanAges 16 years+ - NCT07118930RecruitingPhase 2
Testing sivelestat sodium for heart bypass patients
This trial tests if an anti-inflammatory drug called sivelestat sodium can help people recover after heart bypass surgery. It is for patients having planned bypass surgery on at least two heart arteries.
Nantong, JiangsuAges 18–75 - NCT05979870Enrolling by invitation
AI-enhanced heart MRI for valve disease
This study uses artificial intelligence to improve MRI scans for people with aortic or pulmonary valve disease who are scheduled for valve surgery or a non-surgical valve procedure. It aims to help doctors better assess heart function before treatment.
Gothenburg, GothenburgAges 1 week–18 years - NCT05416385Recruiting
Stress echo scan with special contrast to study carotid plaque
This study uses a heart stress ultrasound test, plus a contrast dye, to look for new blood vessel growth inside carotid plaque (the buildup in neck arteries). It may help doctors better judge the risk of stroke and determine which people need closer care.
Calgary, AlbertaAges 18 years+ - NCT06625073RecruitingPhase 4
SGLT2i for heart transplant recipients
This trial is testing a medication called SGLT2i (a type of diabetes drug that also helps the heart and kidneys) in people who have received a heart transplant. It aims to see if this drug can improve health after transplant.
Palo Alto, CaliforniaAges 18 years+ - NCT05208567Recruiting
Testing heart ultrasound in older adults with weak heart pumping
This trial uses a heart ultrasound test to find people who may have weak heart pumping function, especially in a multi-ethnic community. It may help improve how doctors detect this condition earlier using ultrasound images.
LondonAges 65 years+
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Common questions
- Are there clinical trials for heart diseases?
- Yes. Clin2 currently lists 749 recruiting heart diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.