Clinical trials
Heart Failure With Mildly Reduced Ejection Fraction clinical trials
Below are recruiting heart failure with mildly reduced ejection fraction clinical trials, each written for real people, not researchers. We’re tracking 37 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07204834Enrolling by invitation
Physical activity program for heart failure
This study tests a home-based physical activity program for people with heart failure. The program is designed to be safe and easy to follow, using a smartphone app to guide you, and may help you feel stronger and more active.
GranadaAges 18 years+ - NCT06937320Enrolling by invitationPhase 2
Testing ketone supplements for heart failure with preserved ejection fraction (HFpEF)
This study tests whether a special dietary supplement (ketone esters) can improve exercise ability and heart function in people with a type of heart failure where the heart pumps well but is stiff (HFpEF). You might join if you have stable symptoms, an ejection fraction of 50% or higher, and signs of fluid buildup in the heart.
Durham, North CarolinaAges 18 years+ - NCT06195982Enrolling by invitationPhase 2
Ketone supplement for heart failure with reduced pumping ability
This trial tests whether a ketone supplement can improve heart function and exercise ability in people with heart failure and a reduced ejection fraction. It may help you feel better during daily activities.
Durham, North CarolinaAges 18 years+ - NCT06809686Recruiting
ECG and patient experience study for heart failure
This study collects detailed ECG data and feedback from people with heart failure to better understand the condition and improve care. It involves noninvasive monitoring and a discussion of your symptoms and daily life.
London, LondonAges 45–80 - NCT07552142Recruiting
Heart Failure Check-In: Using Questionnaires to Spot Early Warning Signs
This study asks heart failure patients who recently were hospitalized to answer regular questionnaires about how they're feeling. Researchers want to see if these questions can detect when heart failure is getting worse before a patient needs emergency care.
Moscow, Non-US/Non-CanadianAges 18 years+ - NCT06586008Recruiting
Heart failure ultrasound and recovery study
This trial uses a special ultrasound scoring system to see how well people with a certain type of heart failure (weak heart pumping) are doing. It looks at whether this score can predict how their recovery goes.
Semarang, Central of JavaAges 18–70 - NCT06927440Enrolling by invitation
Registry for children with severe heart failure in China
This study is creating a registry to learn more about children with advanced heart failure. It will help doctors understand who can benefit from treatments like medicine, devices, or transplants.
Shanghai, Shanghai MunicipalityAges Up to 18 years - NCT07650474Recruiting
Mobile app for heart failure management and quality of life
This study tests whether using a mobile phone app to monitor and manage chronic heart failure improves how you feel and function day-to-day. Researchers will check in with you regularly through your phone to track your symptoms and health.
Addis AbabaAges 18–65 - NCT07492498Recruiting
Atrial fibrillation care program to prevent heart failure in rural China
This trial tests a new way of caring for older adults with atrial fibrillation (irregular heartbeat) in rural villages to help prevent heart failure. Trained village doctors will use telemedicine (remote healthcare) to manage your condition.
Yancheng, DongtaiAges 65–80 - NCT07492524Recruiting
Better care for older adults with AF and heart failure in rural China
This trial tests a new way to manage care for older patients with atrial fibrillation and heart failure living in rural areas. It uses village doctors and telemedicine to help monitor and treat these conditions together.
Yancheng, DongtaiAges 65–80 - NCT07076615RecruitingPhase 4
Dapagliflozin for acute heart failure
This trial tests if a medicine called dapagliflozin (Farxiga) helps people with acute heart failure. You may qualify if you are in the hospital or ER for heart failure and need IV water pills.
CairoAges 18 years+ - NCT05235685Recruiting
Testing muscle fatigue during exercise in COPD and heart failure
This study looks at how tired your muscles get during a controlled cycling exercise test in people who have COPD, and—if applicable—heart failure at the same time. It may help researchers understand exercise limits and how to better support you with these conditions.
Échirolles, Auvergne-Rhône-AlpesAges 18 years+ - NCT05672836RecruitingPhase 4
Enavogliflozin after TAVR for heart narrowing with mild heart weakness
This trial tests enavogliflozin (a diabetes medication that may help the heart) in people who have had a TAVR procedure for severe aortic stenosis. It looks at whether the medicine can improve outcomes for people with symptoms and mildly reduced or preserved pumping function.
Bucheon-siAges 19 years+
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Common questions
- Are there clinical trials for heart failure with mildly reduced ejection fraction?
- Yes. Clin2 currently lists 37 recruiting heart failure with mildly reduced ejection fraction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure with mildly reduced ejection fraction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure with mildly reduced ejection fraction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.